PL217858B1 - Fragment apolipoproteiny B lub jego miejsce aktywne, zawierająca go kompozycja farmaceutyczna i szczepionka, zastosowanie tego fragmentu, szczepionka zawierająca przeciwciało przeciwko temu fragmentowi, sposób diagnozowania in vitro oraz zastosowanie tego przeciwciała - Google Patents
Fragment apolipoproteiny B lub jego miejsce aktywne, zawierająca go kompozycja farmaceutyczna i szczepionka, zastosowanie tego fragmentu, szczepionka zawierająca przeciwciało przeciwko temu fragmentowi, sposób diagnozowania in vitro oraz zastosowanie tego przeciwciałaInfo
- Publication number
- PL217858B1 PL217858B1 PL391615A PL39161502A PL217858B1 PL 217858 B1 PL217858 B1 PL 217858B1 PL 391615 A PL391615 A PL 391615A PL 39161502 A PL39161502 A PL 39161502A PL 217858 B1 PL217858 B1 PL 217858B1
- Authority
- PL
- Poland
- Prior art keywords
- fragment
- peptide
- mda
- antibodies
- antibody
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Marine Sciences & Fisheries (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0101232A SE0101232D0 (sv) | 2001-04-05 | 2001-04-05 | Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based elisa for determination of immune responses against oxidized low density liprotein |
| SE0103754A SE0103754L (sv) | 2001-04-05 | 2001-11-09 | Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL217858B1 true PL217858B1 (pl) | 2014-08-29 |
Family
ID=26655437
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL391615A PL217858B1 (pl) | 2001-04-05 | 2002-04-05 | Fragment apolipoproteiny B lub jego miejsce aktywne, zawierająca go kompozycja farmaceutyczna i szczepionka, zastosowanie tego fragmentu, szczepionka zawierająca przeciwciało przeciwko temu fragmentowi, sposób diagnozowania in vitro oraz zastosowanie tego przeciwciała |
| PL02367301A PL367301A1 (en) | 2001-04-05 | 2002-04-05 | Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein |
| PL400308A PL400308A1 (pl) | 2001-04-05 | 2002-04-05 | Terapia immunizacyjna w oparciu o peptydy do leczenia miazdzycy oraz w oparciu o peptydy do okreslania odpowiedzi odpornosci przeciwko utlenionym lipoproteinom o niskiej gestosci |
| PL385189A PL215401B1 (pl) | 2001-04-05 | 2002-04-05 | Fragment apolipoproteiny B lub jego miejsce aktywne, zawierajaca go kompozycja farmaceutyczna i szczepionka, zastosowanie tego fragmentu , szczepionka zawierajaca przeciwcialo przeciwko temu fragmentowi, sposób diagnozowania in vitro oraz zastosowanie tego przeciwciala |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL02367301A PL367301A1 (en) | 2001-04-05 | 2002-04-05 | Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein |
| PL400308A PL400308A1 (pl) | 2001-04-05 | 2002-04-05 | Terapia immunizacyjna w oparciu o peptydy do leczenia miazdzycy oraz w oparciu o peptydy do okreslania odpowiedzi odpornosci przeciwko utlenionym lipoproteinom o niskiej gestosci |
| PL385189A PL215401B1 (pl) | 2001-04-05 | 2002-04-05 | Fragment apolipoproteiny B lub jego miejsce aktywne, zawierajaca go kompozycja farmaceutyczna i szczepionka, zastosowanie tego fragmentu , szczepionka zawierajaca przeciwcialo przeciwko temu fragmentowi, sposób diagnozowania in vitro oraz zastosowanie tego przeciwciala |
Country Status (18)
| Country | Link |
|---|---|
| EP (42) | EP2305708A1 (https=) |
| JP (6) | JP2004529143A (https=) |
| CN (4) | CN101284874B (https=) |
| AT (2) | ATE415423T1 (https=) |
| AU (1) | AU2002246484B8 (https=) |
| BR (1) | BR0208685A (https=) |
| CA (3) | CA2443223C (https=) |
| CY (1) | CY1108817T1 (https=) |
| DE (1) | DE60230029D1 (https=) |
| DK (3) | DK1383526T3 (https=) |
| EE (2) | EE200300487A (https=) |
| ES (2) | ES2317999T3 (https=) |
| IL (4) | IL158285A0 (https=) |
| PL (4) | PL217858B1 (https=) |
| PT (1) | PT1383526E (https=) |
| RU (1) | RU2296582C2 (https=) |
| SE (1) | SE0103754L (https=) |
| WO (1) | WO2002080954A1 (https=) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0103754L (sv) * | 2001-04-05 | 2002-10-06 | Forskarpatent I Syd Ab | Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid |
| US20030105003A1 (en) | 2001-04-05 | 2003-06-05 | Jan Nilsson | Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein |
| PL372925A1 (en) | 2001-09-28 | 2005-08-08 | Esperion Therapeutics Inc. | Prevention and treatment of restenosis by local administration of drug |
| AU2003267905B2 (en) * | 2002-10-04 | 2009-02-05 | Biolnvent International Ab | Peptide-based passive immunization therapy for treatment of atherosclerosis |
| SE0302312D0 (sv) * | 2002-10-04 | 2003-08-27 | Forskarpatent I Syd Ab | Peptide-based passive immunization therapy for treatment of atherosclerosis |
| SE0302422D0 (sv) * | 2003-09-11 | 2003-09-11 | Forskarpatent I Syd Ab | Peptide-based immunization therapy for treatment of atherosclerosis |
| SE0400683D0 (sv) | 2004-03-19 | 2004-03-19 | Forskarpatent I Syd Ab | Use of modified extracellular matrix proteins in diagnosis and treatment of a atherosclerosis |
| JP2007531537A (ja) | 2004-04-06 | 2007-11-08 | セダーズ−シナイ メディカル センター | アポリポタンパク質a−iおよびアポリポタンパク質a−imilanoをコードする組換えアデノ随伴ウイルスベクターによる血管疾患の予防および処置 |
| ATE463254T1 (de) * | 2004-04-15 | 2010-04-15 | Athera Biotechnologies Ab | Antikörper gegen phosphorylcholinkonjugate |
| EP1676602A1 (en) * | 2005-01-04 | 2006-07-05 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Continuous administration of epitopes derived from protein present in atherosclerotic plaque for the treatment of atherosclerosis |
| GB0517878D0 (en) | 2005-09-02 | 2005-10-12 | Bioinvent Int Ab | Immunotherapeutic treatment |
| CA2669863A1 (en) * | 2006-12-22 | 2008-07-03 | Abbott Laboratories | Cardiovascular autoimmune disease panel and methods of using same |
| WO2008104194A1 (en) * | 2007-02-28 | 2008-09-04 | Bioinvent International Ab | Oxidized ldl and antibodies thereto for the treatment of atheroscleroti c plaques |
| CA2681162C (en) | 2007-03-15 | 2015-11-24 | Novartis Ag | Benzyl and pyridine derivatives as modulators of hedgehog pathway |
| ES2897492T3 (es) * | 2007-11-05 | 2022-03-01 | Nordic Bioscience Imaging As | Marcadores bioquímicos para la evaluación de riesgos de CVD |
| US20100041663A1 (en) | 2008-07-18 | 2010-02-18 | Novartis Ag | Organic Compounds as Smo Inhibitors |
| JP5742002B2 (ja) * | 2008-08-15 | 2015-07-01 | 藤倉化成株式会社 | 動脈硬化診断用ポリペプチドマーカー、及び該マーカー等を用いる動脈硬化の検出を補助する方法、並びに動脈硬化診断用キット |
| WO2011060329A1 (en) | 2009-11-14 | 2011-05-19 | Kuang-Yuh Chyu | Immunomodulatory methods and systems for treatment and/or prevention of atherosclerosis |
| US8506964B2 (en) | 2010-02-05 | 2013-08-13 | Cardiovax, Llc | Fusion proteins and related compositions, methods and systems for treatment and/or prevention of atherosclerosis |
| US20130142760A1 (en) | 2010-08-18 | 2013-06-06 | Cedars-Sinai Medical Center | Atherosclerosis inhibition via modulation of monocyte-macrophage phenotype using apo a-i milano gene transfer |
| RU2013126626A (ru) * | 2010-11-12 | 2014-12-20 | Седарс-Синаи Медикал Сентер | Иммуномодулирующие способы и системы для лечения и/или предотвращения гипертензий |
| CN103501806A (zh) * | 2010-11-12 | 2014-01-08 | 赛达斯西奈医疗中心 | 用于治疗和/或预防动脉瘤的免疫调节方法和系统 |
| EP2637686A2 (en) | 2010-11-12 | 2013-09-18 | Cedars-Sinai Medical Center | Immunomodulatory compositions, methods and systems comprising immunogenic fragments of apob100 |
| HUE045163T2 (hu) | 2011-08-09 | 2019-12-30 | Athera Biotechnologies Ab | Új ellenanyagok foszforilkolin ellen |
| CN103906532B (zh) | 2011-08-09 | 2018-01-26 | 阿瑟拉生物技术公司 | 结合磷酰胆碱(pc)和/或pc结合物的抗体 |
| RU2495048C1 (ru) * | 2012-04-18 | 2013-10-10 | Андрей Валентинович Исаев | Пептид, обладающий антиатеросклеротическим действием и композиция для профилактики и лечения атеросклероза сосудов |
| ES2859559T3 (es) * | 2012-11-06 | 2021-10-04 | Les Hopitaux Univ De Geneve | Péptidos miméticos |
| CN103520713B (zh) * | 2013-10-16 | 2015-10-28 | 西北农林科技大学 | 一种ApoB100酵母重组疫苗及其制备方法和应用 |
| CN103860470A (zh) * | 2014-03-05 | 2014-06-18 | 贵州中泰生物科技有限公司 | 一种口服高密度脂蛋白脂质体的制备方法 |
| CN105315364B (zh) * | 2014-06-17 | 2018-09-18 | 广州文瑞生物科技有限公司 | 胶原蛋白vi疫苗预防动脉粥样硬化 |
| CN114085283A (zh) | 2015-05-19 | 2022-02-25 | 拉·约拉过敏反应及免疫医学研究所 | 调节炎症应答及治疗不良心血管事件、病和粥样硬化的人apob100表位、方法和用途 |
| US10858422B2 (en) | 2016-05-31 | 2020-12-08 | Abcentra, Llc | Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody |
| CN108478817B (zh) * | 2018-03-16 | 2020-10-27 | 北京大学 | 一种动脉粥样硬化检测试剂及其制备方法 |
| JP7357646B2 (ja) | 2018-05-29 | 2023-10-06 | アブセントラ,エルエルシー | 乾癬の治療のための組成物及び方法 |
| WO2019232081A1 (en) | 2018-05-29 | 2019-12-05 | Abcentra, Llc | Compositions and methods for treatment of rheumatoid arthritis and accelerated atherosclerosis |
| CN115025210B (zh) * | 2021-03-05 | 2025-09-05 | 香港中文大学 | 减少动脉粥样硬化进展的肽疫苗组合物和药物制剂 |
| CN115025211A (zh) * | 2021-11-02 | 2022-09-09 | 南京理工大学 | 用于动脉粥样硬化治疗的纳米疫苗及其制备方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4970144A (en) | 1984-12-31 | 1990-11-13 | International Genetic Engineering | Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use |
| US5972890A (en) | 1988-05-02 | 1999-10-26 | New England Deaconess Hospital Corporation | Synthetic peptides for arterial imaging |
| WO1993018067A1 (en) * | 1992-03-06 | 1993-09-16 | Abbott Laboratories | Immunocapture assay for direct quantitation of specific lipoprotein cholesterol levels |
| WO1994000592A1 (en) * | 1992-06-26 | 1994-01-06 | Exocell, Inc. | Monoclonal antibodies against glycated low density lipoprotein |
| EP0671926B1 (en) * | 1992-08-11 | 2002-11-13 | President And Fellows Of Harvard College | Immunomodulatory peptides |
| KR0185334B1 (ko) | 1995-11-02 | 1999-04-01 | 김은영 | 인간 혈장 아포지단백질 비-100에 결합하는 생쥐 항체를 암호하는 씨디엔에이 |
| GB9609702D0 (en) * | 1996-05-09 | 1996-07-10 | Royal Free Hosp School Med | Anticoagulant peptides |
| GB9620153D0 (en) * | 1996-09-27 | 1996-11-13 | Univ Strathclyde | Non-naturally occurring lipoprotein particle |
| GB9705831D0 (en) * | 1997-03-20 | 1997-05-07 | Univ Leicester | Oxidised ldl |
| US6635623B1 (en) * | 1997-06-13 | 2003-10-21 | Baylor College Of Medicine | Lipoproteins as nucleic acid vectors |
| US6225070B1 (en) * | 1997-08-07 | 2001-05-01 | The Regents Of The University Of California | Antibodies to oxidation-specific epitopes on lipoprotein and methods for their use in detecting, monitoring and inhibiting the growth of atheroma |
| US6156315A (en) * | 1997-10-10 | 2000-12-05 | The Trustees Of Columbia University In The City Of New York | Method for inhibiting the binding of low density lipoprotein to blood vessel matrix |
| EP0911344B1 (en) * | 1997-10-15 | 2004-03-03 | Fujirebio Inc. | Anti-Apo-B-48 monoclonal antibody, hybridoma, and methods of use |
| EP1062512A4 (en) * | 1998-03-10 | 2001-12-12 | Univ California | METHODS AND TOOLS USED TO IDENTIFY COMPOUNDS THAT MODULATE ATHEROSCLEROSIS BY ALTERATION OF THE LDL-PROTEOGLYCANE BINDING |
| AU5200699A (en) * | 1998-07-13 | 2000-02-01 | University Of Otago | Inhibition of lipoprotein formation |
| IL126447A (en) * | 1998-10-04 | 2004-09-27 | Vascular Biogenics Ltd | An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis |
| JP2003513027A (ja) * | 1999-10-26 | 2003-04-08 | ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア | アテローム性動脈硬化症の診断、結像、治療用の薬剤及びその方法 |
| AU3087801A (en) * | 2000-02-04 | 2001-08-14 | Molecular Dynamics Inc | Human genome-derived single exon nucleic acid probes useful for analysis of geneexpression in human breast and hbl 100 cells |
| MXPA02008616A (es) * | 2000-03-03 | 2003-02-24 | Smithkline Beecham Biolog | Vacuna para el tratamiento de la arterosclerosis. |
| SE0000855D0 (sv) * | 2000-03-15 | 2000-03-15 | Karolinska Innovations Ab | Antigenic composition useful as a vaccine against atherosclerosis |
| GB0017641D0 (en) * | 2000-07-18 | 2000-09-06 | Medigene Oy | Peptides and their use |
| EP1186299A1 (en) * | 2000-09-12 | 2002-03-13 | Universitair Medisch Centrum Utrecht | The diagnosis, prevention, and/or succesful treatment of atherosclerosis, infectious diseases, and disturbances in the immune system |
| EP1592445A4 (en) * | 2000-10-25 | 2007-01-10 | Vincent Agnello | METHOD FOR INHIBITING HEPATITIS C VIRUS (HCV) INFECTION AND OTHER FLAVIRIDAE / I FAMILY VIRUSES, AND OTHER BLOODY-VIRUSES COMPLEXING WITH LOW OR VERY LOW DENSITY LIPOPROTEIN DENSITY, BY PREVENTING VIRAL ENTRY IN A CELL |
| AU2002241603A1 (en) * | 2000-11-10 | 2002-06-03 | University Of Utah Research Foundation | Carrier system for specific artery wall gene delivery |
| SE0103754L (sv) * | 2001-04-05 | 2002-10-06 | Forskarpatent I Syd Ab | Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid |
| KR20030097854A (ko) * | 2001-05-15 | 2003-12-31 | 저팬 이뮤너리서치 래버래터리스 컴퍼니 리미티드 | 고밀도 리포단백질 반응성 펩티드 |
| JP2005504025A (ja) * | 2001-07-20 | 2005-02-10 | アイトゲネシシェ テクニシェ ホッヒシュル チューリッヒ(エーテーハーツェット) | スルフォネート化またはスルフェート化アミノ酸から誘導された生物学的薬剤の使用法と組成物 |
-
2001
- 2001-11-09 SE SE0103754A patent/SE0103754L/xx not_active Application Discontinuation
-
2002
- 2002-04-05 EP EP10180176A patent/EP2305708A1/en not_active Withdrawn
- 2002-04-05 BR BR0208685-9A patent/BR0208685A/pt not_active Application Discontinuation
- 2002-04-05 EP EP10180184A patent/EP2295462A1/en not_active Withdrawn
- 2002-04-05 EP EP10180172A patent/EP2289915A1/en not_active Withdrawn
- 2002-04-05 EP EP10181196A patent/EP2289928A1/en not_active Withdrawn
- 2002-04-05 PL PL391615A patent/PL217858B1/pl unknown
- 2002-04-05 EP EP10180026A patent/EP2295457A1/en not_active Withdrawn
- 2002-04-05 EE EEP200300487A patent/EE200300487A/xx unknown
- 2002-04-05 PT PT02714667T patent/PT1383526E/pt unknown
- 2002-04-05 CN CN2007101953989A patent/CN101284874B/zh not_active Expired - Lifetime
- 2002-04-05 AT AT02714667T patent/ATE415423T1/de active
- 2002-04-05 EP EP08167533A patent/EP2147930A3/en not_active Withdrawn
- 2002-04-05 EE EEP200700052A patent/EE200700052A/xx unknown
- 2002-04-05 CA CA2443223A patent/CA2443223C/en not_active Expired - Lifetime
- 2002-04-05 JP JP2002578993A patent/JP2004529143A/ja not_active Withdrawn
- 2002-04-05 EP EP07119130A patent/EP1918300A3/en not_active Withdrawn
- 2002-04-05 EP EP10180106A patent/EP2289912A1/en not_active Withdrawn
- 2002-04-05 CA CA2827167A patent/CA2827167A1/en not_active Abandoned
- 2002-04-05 CN CN028089405A patent/CN1505525B/zh not_active Expired - Fee Related
- 2002-04-05 EP EP10180193A patent/EP2289917A1/en not_active Withdrawn
- 2002-04-05 EP EP10181273A patent/EP2289935A1/en not_active Withdrawn
- 2002-04-05 CA CA2606839A patent/CA2606839C/en not_active Expired - Lifetime
- 2002-04-05 EP EP10181263A patent/EP2295463A1/en not_active Withdrawn
- 2002-04-05 EP EP10181173A patent/EP2289926A1/en not_active Withdrawn
- 2002-04-05 EP EP10180162.9A patent/EP2295460B1/en not_active Expired - Lifetime
- 2002-04-05 ES ES02714667T patent/ES2317999T3/es not_active Expired - Lifetime
- 2002-04-05 EP EP10181167A patent/EP2289925A1/en not_active Withdrawn
- 2002-04-05 EP EP10181217A patent/EP2289931A1/en not_active Withdrawn
- 2002-04-05 DK DK02714667T patent/DK1383526T3/da active
- 2002-04-05 EP EP08167532A patent/EP2147680A3/en not_active Withdrawn
- 2002-04-05 PL PL02367301A patent/PL367301A1/xx unknown
- 2002-04-05 EP EP10180115A patent/EP2305707A1/en not_active Withdrawn
- 2002-04-05 WO PCT/SE2002/000679 patent/WO2002080954A1/en not_active Ceased
- 2002-04-05 ES ES10181267.5T patent/ES2546293T3/es not_active Expired - Lifetime
- 2002-04-05 EP EP10181203A patent/EP2289929A1/en not_active Withdrawn
- 2002-04-05 DE DE60230029T patent/DE60230029D1/de not_active Expired - Lifetime
- 2002-04-05 EP EP10180828A patent/EP2289921A1/en not_active Withdrawn
- 2002-04-05 EP EP10181213A patent/EP2289930A1/en not_active Withdrawn
- 2002-04-05 AU AU2002246484A patent/AU2002246484B8/en not_active Expired
- 2002-04-05 EP EP10180111A patent/EP2289914A1/en not_active Withdrawn
- 2002-04-05 RU RU2003132443/15A patent/RU2296582C2/ru active
- 2002-04-05 DK DK10181267.5T patent/DK2295464T3/en active
- 2002-04-05 EP EP10180156A patent/EP2295459A1/en not_active Withdrawn
- 2002-04-05 EP EP10180091A patent/EP2305706A1/en not_active Withdrawn
- 2002-04-05 PL PL400308A patent/PL400308A1/pl unknown
- 2002-04-05 EP EP02714667A patent/EP1383526B1/en not_active Expired - Lifetime
- 2002-04-05 AT AT08151489T patent/ATE510851T1/de not_active IP Right Cessation
- 2002-04-05 IL IL15828502A patent/IL158285A0/xx unknown
- 2002-04-05 EP EP10180823A patent/EP2289919A1/en not_active Withdrawn
- 2002-04-05 CN CN201210322795.9A patent/CN103122031B/zh not_active Expired - Lifetime
- 2002-04-05 EP EP10180835A patent/EP2289922A1/en not_active Withdrawn
- 2002-04-05 EP EP10180188A patent/EP2289916A1/en not_active Withdrawn
- 2002-04-05 PL PL385189A patent/PL215401B1/pl unknown
- 2002-04-05 EP EP08167531A patent/EP2147929A3/en not_active Ceased
- 2002-04-05 EP EP10181188A patent/EP2289927A1/en not_active Withdrawn
- 2002-04-05 EP EP08151489A patent/EP2006301B1/en not_active Expired - Lifetime
- 2002-04-05 EP EP10181267.5A patent/EP2295464B1/en not_active Expired - Lifetime
- 2002-04-05 EP EP10180826A patent/EP2289920A1/en not_active Withdrawn
- 2002-04-05 EP EP08158141A patent/EP2147928A3/en not_active Withdrawn
- 2002-04-05 EP EP10180168A patent/EP2295461A1/en not_active Withdrawn
- 2002-04-05 EP EP10181227A patent/EP2289932A1/en not_active Withdrawn
- 2002-04-05 EP EP10181245A patent/EP2289933A1/en not_active Withdrawn
- 2002-04-05 EP EP10180838A patent/EP2289923A1/en not_active Withdrawn
- 2002-04-05 EP EP10180099A patent/EP2295458A1/en not_active Withdrawn
- 2002-04-05 EP EP10180109A patent/EP2289913A1/en not_active Withdrawn
- 2002-04-05 EP EP10181253.5A patent/EP2289934B1/en not_active Expired - Lifetime
- 2002-04-05 CN CNA2009100095655A patent/CN101486766A/zh active Pending
- 2002-04-05 EP EP10180845A patent/EP2289924A1/en not_active Withdrawn
- 2002-04-05 DK DK08151489.5T patent/DK2006301T3/da active
- 2002-04-05 EP EP10180199A patent/EP2289918A1/en not_active Withdrawn
-
2003
- 2003-10-07 IL IL158285A patent/IL158285A/en active IP Right Grant
-
2007
- 2007-12-20 IL IL188286A patent/IL188286A0/en unknown
-
2008
- 2008-01-25 JP JP2008015545A patent/JP2008169215A/ja not_active Withdrawn
- 2008-11-18 IL IL195356A patent/IL195356A0/en unknown
-
2009
- 2009-02-24 CY CY20091100202T patent/CY1108817T1/el unknown
- 2009-06-02 JP JP2009133383A patent/JP5270456B2/ja not_active Expired - Fee Related
-
2010
- 2010-10-26 JP JP2010239478A patent/JP5300820B2/ja not_active Expired - Lifetime
- 2010-10-26 JP JP2010239477A patent/JP5300819B2/ja not_active Expired - Lifetime
-
2013
- 2013-02-25 JP JP2013034312A patent/JP5613890B2/ja not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101284874B (zh) | 以肽为基础的治疗动脉粥样硬化的免疫疗法 | |
| US7544360B2 (en) | Peptide epitopes of apolipoprotein B |