BR0116004A - Derivados de 6-o-carbamoil cetolida de eritromicina úteis como antibacterianos - Google Patents
Derivados de 6-o-carbamoil cetolida de eritromicina úteis como antibacterianosInfo
- Publication number
- BR0116004A BR0116004A BR0116004-4A BR0116004A BR0116004A BR 0116004 A BR0116004 A BR 0116004A BR 0116004 A BR0116004 A BR 0116004A BR 0116004 A BR0116004 A BR 0116004A
- Authority
- BR
- Brazil
- Prior art keywords
- antibacterials
- erythromycin
- carbamoyl
- derivatives useful
- ketolide derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
"DERIVADOS DE 6-O-CARBAMOIL CETOLIDA DE ERITROMICINA úTEIS COMO ANTIBACTERIANOS". Antibacterianos do tipo 6-O-carbamoil cetolida da fórmula: onde R^ 1^, R^ 2^, R^ 3^, R^ 4^, R^ 5^, R^ 6^, X, X<39>, Y e Y<39> são como descritos no relatório e onde os substituintes têm os significados indicados no relatório. Estes compostos são úteis como agentes bacterianos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25154700P | 2000-12-06 | 2000-12-06 | |
US09/773,788 US6472372B1 (en) | 2000-12-06 | 2001-02-01 | 6-O-Carbamoyl ketolide antibacterials |
PCT/US2001/047530 WO2002046204A1 (en) | 2000-12-06 | 2001-12-05 | 6-0-carbamoyl ketolide derivatives of erythromycin useful as antibacterials |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0116004A true BR0116004A (pt) | 2004-06-22 |
Family
ID=26941686
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0116004-4A BR0116004A (pt) | 2000-12-06 | 2001-12-05 | Derivados de 6-o-carbamoil cetolida de eritromicina úteis como antibacterianos |
Country Status (14)
Country | Link |
---|---|
US (2) | US6472372B1 (pt) |
EP (1) | EP1343798A1 (pt) |
JP (1) | JP2004515504A (pt) |
KR (1) | KR20040008115A (pt) |
CN (1) | CN1310934C (pt) |
AU (1) | AU2002230708A1 (pt) |
BR (1) | BR0116004A (pt) |
CA (1) | CA2431032A1 (pt) |
HR (1) | HRP20030468A2 (pt) |
IL (1) | IL156329A0 (pt) |
MX (1) | MXPA03005028A (pt) |
RU (1) | RU2003117027A (pt) |
WO (1) | WO2002046204A1 (pt) |
YU (1) | YU46303A (pt) |
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US11253325B2 (en) | 2018-02-08 | 2022-02-22 | Covidien Lp | System and method for catheter detection in fluoroscopic images and updating displayed position of catheter |
US11269173B2 (en) | 2019-08-19 | 2022-03-08 | Covidien Lp | Systems and methods for displaying medical video images and/or medical 3D models |
US11282251B2 (en) | 2018-05-02 | 2022-03-22 | Covidien Lp | System and method for constructing virtual radial ultrasound images from CT data and performing a surgical navigation procedure using virtual ultrasound images |
US11341720B2 (en) | 2018-02-08 | 2022-05-24 | Covidien Lp | Imaging reconstruction system and method |
US11341692B2 (en) | 2017-06-29 | 2022-05-24 | Covidien Lp | System and method for identifying, marking and navigating to a target using real time two dimensional fluoroscopic data |
US11357593B2 (en) | 2019-01-10 | 2022-06-14 | Covidien Lp | Endoscopic imaging with augmented parallax |
US11364004B2 (en) | 2018-02-08 | 2022-06-21 | Covidien Lp | System and method for pose estimation of an imaging device and for determining the location of a medical device with respect to a target |
US11380060B2 (en) | 2020-01-24 | 2022-07-05 | Covidien Lp | System and method for linking a segmentation graph to volumetric data |
US11529190B2 (en) | 2017-01-30 | 2022-12-20 | Covidien Lp | Enhanced ablation and visualization techniques for percutaneous surgical procedures |
US11547377B2 (en) | 2015-08-06 | 2023-01-10 | Covidien Lp | System and method for navigating to target and performing procedure on target utilizing fluoroscopic-based local three dimensional volume reconstruction |
US11559266B2 (en) | 2015-08-06 | 2023-01-24 | Covidien Lp | System and method for local three dimensional volume reconstruction using a standard fluoroscope |
US11564751B2 (en) | 2019-02-01 | 2023-01-31 | Covidien Lp | Systems and methods for visualizing navigation of medical devices relative to targets |
US11564649B2 (en) | 2017-10-10 | 2023-01-31 | Covidien Lp | System and method for identifying and marking a target in a fluoroscopic three-dimensional reconstruction |
US11617493B2 (en) | 2018-12-13 | 2023-04-04 | Covidien Lp | Thoracic imaging, distance measuring, surgical awareness, and notification system and method |
US11625825B2 (en) | 2019-01-30 | 2023-04-11 | Covidien Lp | Method for displaying tumor location within endoscopic images |
US11627924B2 (en) | 2019-09-24 | 2023-04-18 | Covidien Lp | Systems and methods for image-guided navigation of percutaneously-inserted devices |
US11701179B2 (en) | 2018-07-26 | 2023-07-18 | Covidien Lp | Modeling a collapsed lung using CT data |
US11701492B2 (en) | 2020-06-04 | 2023-07-18 | Covidien Lp | Active distal tip drive |
US11705238B2 (en) | 2018-07-26 | 2023-07-18 | Covidien Lp | Systems and methods for providing assistance during surgery |
US11707241B2 (en) | 2015-08-06 | 2023-07-25 | Covidien Lp | System and method for local three dimensional volume reconstruction using a standard fluoroscope |
US11744643B2 (en) | 2019-02-04 | 2023-09-05 | Covidien Lp | Systems and methods facilitating pre-operative prediction of post-operative tissue function |
US11798178B2 (en) | 2014-07-02 | 2023-10-24 | Covidien Lp | Fluoroscopic pose estimation |
US11793579B2 (en) | 2017-02-22 | 2023-10-24 | Covidien Lp | Integration of multiple data sources for localization and navigation |
US11793402B2 (en) | 2018-12-10 | 2023-10-24 | Covidien Lp | System and method for generating a three-dimensional model of a surgical site |
US11801113B2 (en) | 2018-12-13 | 2023-10-31 | Covidien Lp | Thoracic imaging, distance measuring, and notification system and method |
US11819285B2 (en) | 2019-04-05 | 2023-11-21 | Covidien Lp | Magnetic interference detection systems and methods |
US11847730B2 (en) | 2020-01-24 | 2023-12-19 | Covidien Lp | Orientation detection in fluoroscopic images |
US11864935B2 (en) | 2019-09-09 | 2024-01-09 | Covidien Lp | Systems and methods for pose estimation of a fluoroscopic imaging device and for three-dimensional imaging of body structures |
US11871913B2 (en) | 2014-10-31 | 2024-01-16 | Covidien Lp | Computed tomography enhanced fluoroscopic system, device, and method of utilizing the same |
US11877806B2 (en) | 2018-12-06 | 2024-01-23 | Covidien Lp | Deformable registration of computer-generated airway models to airway trees |
US11922581B2 (en) | 2020-05-08 | 2024-03-05 | Coviden Lp | Systems and methods of controlling an operating room display using an augmented reality headset |
US11918338B2 (en) | 2015-09-23 | 2024-03-05 | Coviden Lp | Elongated catheter having sensor and an extended working channel |
US11925333B2 (en) | 2019-02-01 | 2024-03-12 | Covidien Lp | System for fluoroscopic tracking of a catheter to update the relative position of a target and the catheter in a 3D model of a luminal network |
US11931141B2 (en) | 2008-06-06 | 2024-03-19 | Covidien Lp | Hybrid registration method |
US11931111B2 (en) | 2019-09-09 | 2024-03-19 | Covidien Lp | Systems and methods for providing surgical guidance |
US11944388B2 (en) | 2018-09-28 | 2024-04-02 | Covidien Lp | Systems and methods for magnetic interference correction |
US11950950B2 (en) | 2020-07-24 | 2024-04-09 | Covidien Lp | Zoom detection and fluoroscope movement detection for target overlay |
US11975157B2 (en) | 2019-04-12 | 2024-05-07 | Covidien Lp | Method of manufacturing an elongated catheter having multiple sensors for three-dimensional location of the catheter |
US12008760B2 (en) | 2020-07-24 | 2024-06-11 | Covidien Lp | Systems and methods for estimating the movement of a target using a universal deformation model for anatomic tissue |
US12059281B2 (en) | 2019-08-19 | 2024-08-13 | Covidien Lp | Systems and methods of fluoro-CT imaging for initial registration |
US12064191B2 (en) | 2020-06-03 | 2024-08-20 | Covidien Lp | Surgical tool navigation using sensor fusion |
US12089902B2 (en) | 2019-07-30 | 2024-09-17 | Coviden Lp | Cone beam and 3D fluoroscope lung navigation |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6472372B1 (en) * | 2000-12-06 | 2002-10-29 | Ortho-Mcneil Pharmaceuticals, Inc. | 6-O-Carbamoyl ketolide antibacterials |
WO2003050132A1 (en) * | 2001-12-05 | 2003-06-19 | Ortho-Mcneil Pharmaceutical, Inc. | 6-o-acyl ketolide derivatives of erythromycine useful as antibacterials |
WO2003090761A1 (en) * | 2002-04-25 | 2003-11-06 | Abbott Laboratories | 9-oxime macrolide antibacterials |
WO2003102010A1 (en) * | 2002-05-31 | 2003-12-11 | Janssen Pharmaceutica N.V. | 3-descladinosyl-6-o-carbamoyl and 6-o-carbonoyl macrolide antibacterial agents |
US20050250713A1 (en) * | 2004-04-26 | 2005-11-10 | Bin Zhu | 11,12-Cyclic thiocarbamate macrolide antibacterial agents |
JP2008508322A (ja) * | 2004-07-28 | 2008-03-21 | ランバクシー ラボラトリーズ リミテッド | 抗菌剤としてのケトライド誘導体 |
WO2006046112A2 (en) * | 2004-10-25 | 2006-05-04 | Ranbaxy Laboratories Limited | Ketolide derivatives as antibacterial agents |
WO2007060518A2 (en) * | 2005-11-23 | 2007-05-31 | Ranbaxy Laboratories Limited | Ketolide derivatives as antibacterial agents |
US20090130225A1 (en) * | 2005-11-23 | 2009-05-21 | Anjan Chakrabarti | Macrolides derivatives as antibacterial agents |
JP2008044880A (ja) | 2006-08-15 | 2008-02-28 | Bayer Cropscience Ag | 殺虫性イソオキサゾリン類 |
CA2662142A1 (en) * | 2006-08-30 | 2008-09-04 | Pace University | Antimicrobial compositions |
GB201105633D0 (en) * | 2011-04-01 | 2011-05-18 | Norbrook Lab Ltd | Antibotic compounds |
CN103242239B (zh) * | 2013-05-20 | 2015-09-23 | 洛阳师范学院 | 多取代嘧啶基苯甲醇及其制备方法 |
CN106928294A (zh) * | 2017-03-22 | 2017-07-07 | 上海启雁实业有限公司 | 制备酮内酯大环内酯类抗生素的方法 |
CN112300221B (zh) * | 2020-11-11 | 2022-04-15 | 艾美科健(中国)生物医药有限公司 | 一种加米霉素的合成方法 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
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GB8521402D0 (en) * | 1985-08-28 | 1985-10-02 | Beecham Group Plc | Chemical compounds |
IL99995A (en) * | 1990-11-21 | 1997-11-20 | Roussel Uclaf | Erythromycin derivatives, their preparation and pharmaceutical compositions containing them |
US5559256A (en) * | 1992-07-20 | 1996-09-24 | E. R. Squibb & Sons, Inc. | Aminediol protease inhibitors |
IL123551A0 (en) | 1995-11-08 | 1998-10-30 | Abbott Lab | Tricyclic erythromycin derivatives |
CN1209063A (zh) * | 1995-12-29 | 1999-02-24 | 史密丝克莱恩比彻姆公司 | 玻连蛋白受体拮抗剂 |
UA51730C2 (uk) * | 1996-09-04 | 2002-12-16 | Ебботт Лабораторіз | 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців |
PL188173B1 (pl) | 1996-09-04 | 2004-12-31 | Abbott Lab | Pochodne erytromycyny, sposób wytwarzania pochodnych erytromycyny i środek o działaniu przeciwbakteryjnym |
WO1998009976A1 (fr) * | 1996-09-06 | 1998-03-12 | The Nisshin Oil Mills, Ltd. | Derives de glycolipides sulfates et compositions medicinales obtenues a partir de ces derniers |
CZ180799A3 (cs) | 1996-11-27 | 1999-09-15 | Taisho Pharmaceutical Co., Ltd. | Deriváty erythromycinu A |
FR2757168B1 (fr) * | 1996-12-12 | 1999-06-11 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
UA59384C2 (uk) * | 1996-12-20 | 2003-09-15 | Пфайзер, Інк. | Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі |
CO4990960A1 (es) * | 1997-10-29 | 2000-12-26 | Abbott Lab | Derivados de cetolidos 2-halo-6-o sustituidos |
CO4990972A1 (es) * | 1997-10-29 | 2000-12-26 | Abbott Lab | Derivados de eritromicina en puente 6,11 |
AP1060A (en) | 1998-01-02 | 2002-04-23 | Pfizer Prod Inc | Novel erythromycin derivatives. |
JP2002542197A (ja) | 1999-04-16 | 2002-12-10 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | ケトライド抗菌剤 |
DE60030847T2 (de) | 1999-04-16 | 2007-04-19 | Kosan Biosciences, Inc., Hayward | Antiinfektiöse makrolidderivate |
EP1181300B1 (en) | 1999-06-07 | 2003-09-17 | Abbott Laboratories | 6-o-carbamate ketolide derivatives |
ATE397615T1 (de) | 1999-12-02 | 2008-06-15 | Abbott Lab | 6-o-alkyl-2-nor-2-substituierte ketolidderivate |
EP1146051A3 (en) | 2000-04-10 | 2001-10-31 | Pfizer Products Inc. | Erythromycin A derivatives |
US6472372B1 (en) * | 2000-12-06 | 2002-10-29 | Ortho-Mcneil Pharmaceuticals, Inc. | 6-O-Carbamoyl ketolide antibacterials |
-
2001
- 2001-02-01 US US09/773,788 patent/US6472372B1/en not_active Expired - Lifetime
- 2001-12-05 BR BR0116004-4A patent/BR0116004A/pt not_active IP Right Cessation
- 2001-12-05 MX MXPA03005028A patent/MXPA03005028A/es active IP Right Grant
- 2001-12-05 CN CNB018223087A patent/CN1310934C/zh not_active Expired - Fee Related
- 2001-12-05 US US10/011,937 patent/US6613747B2/en not_active Expired - Lifetime
- 2001-12-05 JP JP2002547941A patent/JP2004515504A/ja active Pending
- 2001-12-05 YU YU46303A patent/YU46303A/sh unknown
- 2001-12-05 RU RU2003117027/04A patent/RU2003117027A/ru not_active Application Discontinuation
- 2001-12-05 AU AU2002230708A patent/AU2002230708A1/en not_active Abandoned
- 2001-12-05 KR KR10-2003-7007629A patent/KR20040008115A/ko not_active Application Discontinuation
- 2001-12-05 CA CA002431032A patent/CA2431032A1/en not_active Abandoned
- 2001-12-05 WO PCT/US2001/047530 patent/WO2002046204A1/en active Application Filing
- 2001-12-05 EP EP01990950A patent/EP1343798A1/en not_active Withdrawn
- 2001-12-05 IL IL15632901A patent/IL156329A0/xx unknown
-
2003
- 2003-06-06 HR HR20030468A patent/HRP20030468A2/hr not_active Application Discontinuation
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Also Published As
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RU2003117027A (ru) | 2004-12-10 |
CA2431032A1 (en) | 2002-06-13 |
JP2004515504A (ja) | 2004-05-27 |
MXPA03005028A (es) | 2004-01-29 |
EP1343798A1 (en) | 2003-09-17 |
US6472372B1 (en) | 2002-10-29 |
YU46303A (sh) | 2006-05-25 |
US20030013663A1 (en) | 2003-01-16 |
WO2002046204A1 (en) | 2002-06-13 |
CN1310934C (zh) | 2007-04-18 |
US20020115620A1 (en) | 2002-08-22 |
US6613747B2 (en) | 2003-09-02 |
HRP20030468A2 (en) | 2005-04-30 |
KR20040008115A (ko) | 2004-01-28 |
CN1543472A (zh) | 2004-11-03 |
IL156329A0 (en) | 2004-01-04 |
AU2002230708A1 (en) | 2002-06-18 |
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