BR0012901A - Medicamentos de ß - carbolina - Google Patents

Medicamentos de ß - carbolina

Info

Publication number
BR0012901A
BR0012901A BR0012901-1A BR0012901A BR0012901A BR 0012901 A BR0012901 A BR 0012901A BR 0012901 A BR0012901 A BR 0012901A BR 0012901 A BR0012901 A BR 0012901A
Authority
BR
Brazil
Prior art keywords
carboline
medicines
compound
solvates
formula
Prior art date
Application number
BR0012901-1A
Other languages
English (en)
Inventor
Neil R Anderson
Kerry J Hartauer
Martha A Kral
Gregory A Stephenson
Original Assignee
Lilly Icos Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22520112&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0012901(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Icos Llc filed Critical Lilly Icos Llc
Publication of BR0012901A publication Critical patent/BR0012901A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

"MEDICAMENTOS DE <225>-CARBOLINA". é revelado um composto de fórmula estrutural (I) e seus sais e solvatos farmaceuticamente aceitáveis, em que o composto está em forma de medicamento livre.
BR0012901-1A 1999-08-03 2000-08-01 Medicamentos de ß - carbolina BR0012901A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14704899P 1999-08-03 1999-08-03
PCT/US2000/020981 WO2001008688A2 (en) 1999-08-03 2000-08-01 Beta-carboline drug products

Publications (1)

Publication Number Publication Date
BR0012901A true BR0012901A (pt) 2002-04-16

Family

ID=22520112

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0012901-1A BR0012901A (pt) 1999-08-03 2000-08-01 Medicamentos de ß - carbolina

Country Status (33)

Country Link
EP (1) EP1200092B1 (pt)
JP (1) JP4456788B2 (pt)
KR (1) KR20020063842A (pt)
CN (2) CN101134019A (pt)
AR (1) AR033953A1 (pt)
AT (1) ATE264680T1 (pt)
AU (1) AU773666B2 (pt)
BR (1) BR0012901A (pt)
CA (1) CA2380087C (pt)
CO (1) CO5200849A1 (pt)
CZ (1) CZ300151B6 (pt)
DE (1) DE60010089T2 (pt)
DK (1) DK1200092T3 (pt)
DZ (1) DZ3180A1 (pt)
EA (1) EA004302B9 (pt)
ES (1) ES2220506T3 (pt)
HK (1) HK1044278B (pt)
HR (1) HRP20020091B1 (pt)
HU (1) HU229443B1 (pt)
IL (1) IL147642A0 (pt)
MX (1) MXPA02001197A (pt)
MY (1) MY125428A (pt)
NO (1) NO321602B1 (pt)
NZ (1) NZ516613A (pt)
PE (1) PE20010480A1 (pt)
PL (1) PL199469B1 (pt)
PT (1) PT1200092E (pt)
SK (1) SK286365B6 (pt)
SV (1) SV2002000137A (pt)
TW (1) TWI235658B (pt)
UA (1) UA71629C2 (pt)
WO (1) WO2001008688A2 (pt)
ZA (1) ZA200200825B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2310166T3 (es) * 1999-08-03 2009-01-01 Lilly Icos Llc Composicion farmaceutica que contiene tadalafil.
WO2006049986A1 (en) * 2004-10-28 2006-05-11 Dr. Reddy's Laboratories Ltd. Polymorphic forms of tadalafil
EP2036545A1 (en) * 2006-01-05 2009-03-18 Teva Pharmaceutical Industries Ltd. Aripiprazole tablets
DE102007028869A1 (de) 2007-06-22 2008-12-24 Ratiopharm Gmbh Verfahren zur Herstellung eines Arzneimittels enthaltend Tadalafil
MD4009C2 (ro) * 2008-07-15 2010-08-31 Институт Химии Академии Наук Молдовы Utilizarea 1-metil-4-(N-metilaminobutil-4)-β-carbolinei în calitate de remediu antituberculos
DE102009033396A1 (de) 2009-07-16 2011-01-20 Ratiopharm Gmbh Wässrige Lösung und gelatinierte Zusammensetzung umfassend einen Phosphodiesterase-5-Inhibitor sowie diesbezügliche Verfahren und Verwendung
DE102009035211A1 (de) 2009-07-29 2011-02-17 Ratiopharm Gmbh Copräzipitate umfassend einen Phosphodiesterase-5-Inhibitor (PDE-5-Inhibitor) und einen pharmazeutisch verträglichen Trägerstoff, ihre Herstellung und Verwendung
WO2012085927A2 (en) * 2010-12-02 2012-06-28 Mylan Laboratories, Limited Tadalafil compositions
WO2012095151A1 (en) 2010-12-23 2012-07-19 Zaklady Farmaceutyczne Polpharma Sa Solid pharmaceutical dosage forms comprising tadalafil and methods of preparation thereof
WO2012107092A1 (en) 2011-02-10 2012-08-16 Synthon Bv Pharmaceutical composition comprising tadalafil and a cyclodextrin
RU2013141446A (ru) 2011-02-10 2015-03-20 Синтон Бв Фармацевтическая композиция, содержащая тадалафил и циклодекстрин
WO2012107090A1 (en) 2011-02-10 2012-08-16 Synthon Bv Granulated composition comprising tadalafil and a disintegrant
JP5930686B2 (ja) * 2011-12-07 2016-06-08 株式会社トクヤマ 溶解性および安定性の向上した難溶性医薬品原体及びその製造方法
EP3460864A1 (de) 2012-03-15 2019-03-27 Merck Patent GmbH Elektronische vorrichtungen
WO2014003677A1 (en) * 2012-06-28 2014-01-03 Xspray Microparticles Ab Pharmaceutical compositions comprising solid dispersion particles containing tadalafil
WO2014003678A1 (en) * 2012-06-28 2014-01-03 Xspray Microparticles Ab Pharmaceutical compositions comprising ambrisentan and solid dispersion particles containing tadalafil
CN105310984A (zh) * 2014-06-10 2016-02-10 合肥贝霓医药科技有限公司 一种pde5抑制剂的超微粉体及其制备方法
PL3111929T3 (pl) * 2014-06-24 2019-01-31 Wooshin Labottach Co., Ltd. Ulegający rozpadowi w jamie ustnej preparat w postaci błony zawierający tadalafil i sposób jego wytwarzania
EP3466951B1 (en) 2014-07-23 2022-01-19 KRKA, d.d., Novo mesto A process for the preparation of cgmp-phosphodiesterase inhibitor and oral pharmaceutical formulation comprising tadalafil co-precipitates
JP2016106139A (ja) * 2016-03-07 2016-06-16 株式会社トクヤマ 溶解性および安定性の向上した難溶性医薬品原体及びその製造方法
SG11202006080SA (en) * 2017-12-26 2020-07-29 Ftf Pharma Private Ltd Liquid oral formulations for pde v inhibitors
RS60973B1 (sr) 2018-01-10 2020-11-30 Gap S A Meke želatinske kapsule koje sadrže suspenziju tadalafila
CN110638770B (zh) * 2019-10-25 2022-04-05 株洲千金药业股份有限公司 他达拉非片剂的制备方法及以该方法制得的片剂
WO2023227185A1 (en) * 2022-05-27 2023-11-30 Rontis Hellas S.A. Improved pharmaceutical composition containing tadalafil and nanomilling process for the preparation thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5618845A (en) * 1994-10-06 1997-04-08 Cephalon, Inc. Acetamide derivative having defined particle size
GB9511220D0 (en) * 1995-06-02 1995-07-26 Glaxo Group Ltd Solid dispersions

Also Published As

Publication number Publication date
HU229443B1 (en) 2013-12-30
WO2001008688A3 (en) 2001-08-16
DZ3180A1 (fr) 2001-02-08
HRP20020091B1 (en) 2006-02-28
MY125428A (en) 2006-07-31
CA2380087A1 (en) 2001-02-08
NO321602B1 (no) 2006-06-12
MXPA02001197A (es) 2003-02-12
KR20020063842A (ko) 2002-08-05
EA004302B1 (ru) 2004-02-26
PL353268A1 (en) 2003-11-03
ES2220506T3 (es) 2004-12-16
DE60010089D1 (de) 2004-05-27
HRP20020091A2 (en) 2004-02-29
HUP0202781A2 (hu) 2002-12-28
AR033953A1 (es) 2004-01-21
EA200200119A1 (ru) 2002-06-27
IL147642A0 (en) 2002-08-14
ZA200200825B (en) 2003-04-30
ATE264680T1 (de) 2004-05-15
HUP0202781A3 (en) 2003-10-28
CA2380087C (en) 2007-05-01
DE60010089T2 (de) 2004-10-14
JP4456788B2 (ja) 2010-04-28
CZ300151B6 (cs) 2009-02-25
AU773666B2 (en) 2004-06-03
EP1200092B1 (en) 2004-04-21
CZ2002387A3 (cs) 2002-10-16
SV2002000137A (es) 2002-06-07
JP2003505510A (ja) 2003-02-12
WO2001008688A2 (en) 2001-02-08
SK286365B6 (sk) 2008-08-05
UA71629C2 (en) 2004-12-15
SK1722002A3 (en) 2002-05-09
PL199469B1 (pl) 2008-09-30
NO20020531D0 (no) 2002-02-01
PE20010480A1 (es) 2001-05-26
EA004302B9 (ru) 2019-01-31
CN101134019A (zh) 2008-03-05
CO5200849A1 (es) 2002-09-27
NO20020531L (no) 2002-04-03
AU6508400A (en) 2001-02-19
TWI235658B (en) 2005-07-11
NZ516613A (en) 2003-08-29
EP1200092A2 (en) 2002-05-02
HK1044278A1 (en) 2002-10-18
CN1377270A (zh) 2002-10-30
DK1200092T3 (da) 2004-08-16
PT1200092E (pt) 2004-07-30
HK1044278B (zh) 2004-10-08

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 13 E 25 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.