BG63539B1 - Подобрен метод за получаване на r(+)1,2,3,6-тетрахидро-4- фенил-1-[(3-фенил-3-циклохексен-1-ил)метил]пиридин - Google Patents

Подобрен метод за получаване на r(+)1,2,3,6-тетрахидро-4- фенил-1-[(3-фенил-3-циклохексен-1-ил)метил]пиридин Download PDF

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Publication number
BG63539B1
BG63539B1 BG101271A BG10127197A BG63539B1 BG 63539 B1 BG63539 B1 BG 63539B1 BG 101271 A BG101271 A BG 101271A BG 10127197 A BG10127197 A BG 10127197A BG 63539 B1 BG63539 B1 BG 63539B1
Authority
BG
Bulgaria
Prior art keywords
formula
compound
solvent
give
phenyl
Prior art date
Application number
BG101271A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG101271A (en
Inventor
Donald BUTLER
Jodette Gailey
Tung Le
III William SMITH
David Wustrow
Original Assignee
Warner-Lambert Company Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company Llc filed Critical Warner-Lambert Company Llc
Publication of BG101271A publication Critical patent/BG101271A/xx
Publication of BG63539B1 publication Critical patent/BG63539B1/bg

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/487Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BG101271A 1994-09-12 1997-02-27 Подобрен метод за получаване на r(+)1,2,3,6-тетрахидро-4- фенил-1-[(3-фенил-3-циклохексен-1-ил)метил]пиридин BG63539B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/304,074 US5710277A (en) 1994-09-12 1994-09-12 Process for R (+) 1,2,3,6-tetrahydro-4-phenyl-1- (3-phenyl-3-cyclohexen-1-yl)methyl!pyridine, a central nervous system agent
PCT/US1995/009511 WO1996008473A1 (en) 1994-09-12 1995-07-28 Improved process for r (+) 1,2,3,6-tetrahydro-4-phenyl-1-[(3-phenyl-3-cyclohexen-1-yl)methyl]pyridine, a central nervous system agent

Publications (2)

Publication Number Publication Date
BG101271A BG101271A (en) 1998-03-31
BG63539B1 true BG63539B1 (bg) 2002-04-30

Family

ID=23174951

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101271A BG63539B1 (bg) 1994-09-12 1997-02-27 Подобрен метод за получаване на r(+)1,2,3,6-тетрахидро-4- фенил-1-[(3-фенил-3-циклохексен-1-ил)метил]пиридин

Country Status (18)

Country Link
US (1) US5710277A (pl)
EP (1) EP0781274A1 (pl)
JP (1) JPH10505610A (pl)
KR (1) KR100379069B1 (pl)
BG (1) BG63539B1 (pl)
CA (1) CA2194000A1 (pl)
CZ (1) CZ288258B6 (pl)
HR (1) HRP950471A2 (pl)
HU (1) HU219244B (pl)
MD (1) MD1787G2 (pl)
MX (1) MX9700331A (pl)
NO (2) NO307881B1 (pl)
NZ (1) NZ290701A (pl)
PL (2) PL184241B1 (pl)
RU (1) RU2144026C1 (pl)
TJ (1) TJ257B (pl)
WO (1) WO1996008473A1 (pl)
ZA (1) ZA957615B (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6433098B1 (en) 1994-06-13 2002-08-13 Rohm And Haas Company Process of preparing curable compositions and compositions therefrom
US6362301B1 (en) * 1994-06-13 2002-03-26 Rohm And Haas Company Curable composition
CN115572224A (zh) * 2021-06-21 2023-01-06 上海茂晟康慧科技有限公司 一种(s)-(-)-3-环己烯甲酸的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1189982A (fr) * 1957-10-10 1959-10-08 Centre Nat Rech Scient Procédé de préparation de cycloheptadiènones-2-4 substituées
US5314896A (en) * 1991-11-20 1994-05-24 Warner-Lambert Company 1,3-substituted cycloalkenes and cycloalkanes as central nervous system agents

Also Published As

Publication number Publication date
MX9700331A (es) 1997-05-31
NO995678D0 (no) 1999-11-19
CZ74097A3 (en) 1997-12-17
NO307881B1 (no) 2000-06-13
MD970146A (en) 1999-02-28
PL184075B1 (pl) 2002-08-30
AU697702B2 (en) 1998-10-15
NO971122D0 (no) 1997-03-11
AU3151595A (en) 1996-03-29
KR100379069B1 (ko) 2003-07-23
NO971122L (no) 1997-03-11
WO1996008473A1 (en) 1996-03-21
CA2194000A1 (en) 1996-03-21
PL319076A1 (en) 1997-07-21
CZ288258B6 (en) 2001-05-16
HRP950471A2 (en) 1997-08-31
NO995678L (no) 1997-03-11
RU2144026C1 (ru) 2000-01-10
TJ257B (en) 2000-05-12
MD1787F2 (en) 2001-11-30
ZA957615B (en) 1996-04-22
HUT77531A (hu) 1998-05-28
US5710277A (en) 1998-01-20
NO309084B1 (no) 2000-12-11
PL184241B1 (pl) 2002-09-30
NZ290701A (en) 1998-04-27
EP0781274A1 (en) 1997-07-02
BG101271A (en) 1998-03-31
JPH10505610A (ja) 1998-06-02
HU219244B (en) 2001-03-28
MD1787G2 (ro) 2002-05-31

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