BG63305B1 - Фармацевтични пиперазинови производни - Google Patents

Фармацевтични пиперазинови производни Download PDF

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Publication number
BG63305B1
BG63305B1 BG101601A BG10160197A BG63305B1 BG 63305 B1 BG63305 B1 BG 63305B1 BG 101601 A BG101601 A BG 101601A BG 10160197 A BG10160197 A BG 10160197A BG 63305 B1 BG63305 B1 BG 63305B1
Authority
BG
Bulgaria
Prior art keywords
methyl
piperazinylidene
dioxy
benzylidene
methylbenzamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
BG101601A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG101601A (en
Inventor
Philip ASHWORTH
Sukhjit Hunjan
Ian PRETSWELL
Hamish Rider
Stephen Brocchini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xenova Ltd
Original Assignee
Xenova Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenova Ltd filed Critical Xenova Ltd
Publication of BG101601A publication Critical patent/BG101601A/xx
Publication of BG63305B1 publication Critical patent/BG63305B1/bg
Anticipated expiration legal-status Critical
Active legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
BG101601A 1994-12-23 1997-06-11 Фармацевтични пиперазинови производни Active BG63305B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9426090.8A GB9426090D0 (en) 1994-12-23 1994-12-23 Pharmaceutical compounds
PCT/GB1995/003029 WO1996020180A1 (en) 1994-12-23 1995-12-22 Piperazine-2,5-dione derivatives as modulators of multidrug resistance

Publications (2)

Publication Number Publication Date
BG101601A BG101601A (en) 1998-02-27
BG63305B1 true BG63305B1 (bg) 2001-09-28

Family

ID=10766502

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101601A Active BG63305B1 (bg) 1994-12-23 1997-06-11 Фармацевтични пиперазинови производни

Country Status (28)

Country Link
US (1) US5935955A (fi)
EP (1) EP0799210B1 (fi)
JP (1) JPH10511385A (fi)
KR (1) KR100412167B1 (fi)
CN (1) CN1108294C (fi)
AT (1) ATE204569T1 (fi)
AU (1) AU700891B2 (fi)
BG (1) BG63305B1 (fi)
BR (1) BR9510429A (fi)
CA (1) CA2207548A1 (fi)
CZ (1) CZ288935B6 (fi)
DE (1) DE69522342T2 (fi)
DK (1) DK0799210T3 (fi)
ES (1) ES2160726T3 (fi)
FI (1) FI972661A (fi)
GB (2) GB9426090D0 (fi)
HK (1) HK1001974A1 (fi)
HU (1) HUT77740A (fi)
IL (1) IL116526A (fi)
MY (1) MY131762A (fi)
NO (1) NO308532B1 (fi)
NZ (1) NZ297849A (fi)
PL (1) PL186851B1 (fi)
PT (1) PT799210E (fi)
SK (1) SK283385B6 (fi)
UA (1) UA61879C2 (fi)
WO (1) WO1996020180A1 (fi)
ZA (1) ZA9510908B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9708805D0 (en) 1997-05-01 1997-06-25 Smithkline Beecham Plc Compounds
GB9810876D0 (en) 1998-05-20 1998-07-22 Smithkline Beecham Plc Compounds
SK4782001A3 (en) 1998-10-08 2001-11-06 Smithkline Beecham Plc Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents)
EP1210093A4 (en) * 1999-09-03 2005-01-12 Polytherics Ltd DEGRADABLE POLYMERS
US6828412B1 (en) * 1999-09-03 2004-12-07 School Of Pharmacy, University Of London Degradable polymers
EP2266607A3 (en) 1999-10-01 2011-04-20 Immunogen, Inc. Immunoconjugates for treating cancer
ES2294026T3 (es) 2000-09-06 2008-04-01 Ap Pharma, Inc. Polimeros degradables de poliacetal.
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
EP1451856A2 (en) * 2001-11-07 2004-09-01 Pharmacia Corporation Methods of promoting uptake and nuclear accumulation of polyamides in eukaryotic cells
US8710062B2 (en) * 2011-03-11 2014-04-29 Taipei Medical University Piperazinedione compounds
CN103396372B (zh) * 2013-08-09 2015-05-20 中国科学院南海海洋研究所 一类2,5-二酮哌嗪衍生物及其制备方法和在制备抗海洋污损生物防除剂中的应用
KR102468480B1 (ko) * 2018-12-27 2022-11-18 홀로스메딕 주식회사 신규한 화합물 및 이를 포함하는 항암 활성 증진용 약학 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4567193A (en) * 1992-07-10 1994-01-31 Laboratoires Glaxo S.A. Anilide derivatives
AU664920B2 (en) * 1992-08-14 1995-12-07 Asahi Breweries, Ltd. Peptide having allergenicity
GB9217331D0 (en) * 1992-08-14 1992-09-30 Xenova Ltd Pharmaceutical compounds
GB9402807D0 (en) * 1994-02-14 1994-04-06 Xenova Ltd Pharmaceutical compounds
GB9410387D0 (en) * 1994-05-24 1994-07-13 Xenova Ltd Pharmaceutical compounds

Also Published As

Publication number Publication date
BR9510429A (pt) 1998-07-07
DE69522342T2 (de) 2002-01-03
KR100412167B1 (ko) 2004-05-27
IL116526A0 (en) 1996-03-31
GB9426090D0 (en) 1995-02-22
ZA9510908B (en) 1996-06-24
ATE204569T1 (de) 2001-09-15
DE69522342D1 (de) 2001-09-27
BG101601A (en) 1998-02-27
CN1108294C (zh) 2003-05-14
NO972938D0 (no) 1997-06-23
FI972661A (fi) 1997-08-22
NO308532B1 (no) 2000-09-25
CA2207548A1 (en) 1996-07-04
AU700891B2 (en) 1999-01-14
CZ190297A3 (cs) 1998-01-14
DK0799210T3 (da) 2001-10-01
EP0799210B1 (en) 2001-08-22
SK83597A3 (en) 1998-04-08
NO972938L (no) 1997-06-23
HUT77740A (hu) 1998-07-28
CZ288935B6 (cs) 2001-09-12
US5935955A (en) 1999-08-10
WO1996020180A1 (en) 1996-07-04
JPH10511385A (ja) 1998-11-04
ES2160726T3 (es) 2001-11-16
MY131762A (en) 2007-08-30
NZ297849A (en) 1999-04-29
PT799210E (pt) 2002-01-30
UA61879C2 (en) 2003-12-15
CN1176637A (zh) 1998-03-18
AU4310296A (en) 1996-07-19
SK283385B6 (sk) 2003-06-03
EP0799210A1 (en) 1997-10-08
GB2311780A (en) 1997-10-08
HK1001974A1 (en) 1998-07-24
FI972661A0 (fi) 1997-06-19
PL320915A1 (en) 1997-11-10
PL186851B1 (pl) 2004-03-31
IL116526A (en) 1999-11-30
GB9712179D0 (en) 1997-08-13
GB2311780B (en) 1999-03-03

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