DK0799210T3 - Piperazin-2,5-dionderivater som modulatorer af multiresistens - Google Patents
Piperazin-2,5-dionderivater som modulatorer af multiresistensInfo
- Publication number
- DK0799210T3 DK0799210T3 DK95941799T DK95941799T DK0799210T3 DK 0799210 T3 DK0799210 T3 DK 0799210T3 DK 95941799 T DK95941799 T DK 95941799T DK 95941799 T DK95941799 T DK 95941799T DK 0799210 T3 DK0799210 T3 DK 0799210T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- modulators
- formula
- piperazine
- resistance
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Electron Tubes For Measurement (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9426090.8A GB9426090D0 (en) | 1994-12-23 | 1994-12-23 | Pharmaceutical compounds |
| PCT/GB1995/003029 WO1996020180A1 (en) | 1994-12-23 | 1995-12-22 | Piperazine-2,5-dione derivatives as modulators of multidrug resistance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0799210T3 true DK0799210T3 (da) | 2001-10-01 |
Family
ID=10766502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95941799T DK0799210T3 (da) | 1994-12-23 | 1995-12-22 | Piperazin-2,5-dionderivater som modulatorer af multiresistens |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5935955A (fi) |
| EP (1) | EP0799210B1 (fi) |
| JP (1) | JPH10511385A (fi) |
| KR (1) | KR100412167B1 (fi) |
| CN (1) | CN1108294C (fi) |
| AT (1) | ATE204569T1 (fi) |
| AU (1) | AU700891B2 (fi) |
| BG (1) | BG63305B1 (fi) |
| BR (1) | BR9510429A (fi) |
| CA (1) | CA2207548A1 (fi) |
| CZ (1) | CZ288935B6 (fi) |
| DE (1) | DE69522342T2 (fi) |
| DK (1) | DK0799210T3 (fi) |
| ES (1) | ES2160726T3 (fi) |
| FI (1) | FI972661A (fi) |
| GB (2) | GB9426090D0 (fi) |
| HK (1) | HK1001974A1 (fi) |
| HU (1) | HUT77740A (fi) |
| IL (1) | IL116526A (fi) |
| MY (1) | MY131762A (fi) |
| NO (1) | NO308532B1 (fi) |
| NZ (1) | NZ297849A (fi) |
| PL (1) | PL186851B1 (fi) |
| PT (1) | PT799210E (fi) |
| SK (1) | SK283385B6 (fi) |
| UA (1) | UA61879C2 (fi) |
| WO (1) | WO1996020180A1 (fi) |
| ZA (1) | ZA9510908B (fi) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9708805D0 (en) | 1997-05-01 | 1997-06-25 | Smithkline Beecham Plc | Compounds |
| GB9810876D0 (en) | 1998-05-20 | 1998-07-22 | Smithkline Beecham Plc | Compounds |
| US6605607B1 (en) | 1998-10-08 | 2003-08-12 | Smithkline Beecham P.L.C. | Tetrahydrobenzazepine derivatives useful as modulators of dopamine D3 receptors (antipsychotic agents) |
| JP2003528939A (ja) * | 1999-09-03 | 2003-09-30 | スクール オブ ファーマシー， ユニヴァーシティ オブ ロンドン | 分解性ポリマー |
| US6828412B1 (en) * | 1999-09-03 | 2004-12-07 | School Of Pharmacy, University Of London | Degradable polymers |
| CA2385528C (en) | 1999-10-01 | 2013-12-10 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
| AU2001288829A1 (en) | 2000-09-06 | 2002-03-22 | Ap Pharma, Inc. | Degradable polyacetal polymers |
| US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
| BR0213989A (pt) * | 2001-11-07 | 2005-03-01 | Pharmacia Corp | Métodos para promover a absorção e acúmulo nuclear de poliamidas em células eucarióticas |
| US8710062B2 (en) * | 2011-03-11 | 2014-04-29 | Taipei Medical University | Piperazinedione compounds |
| CN103396372B (zh) * | 2013-08-09 | 2015-05-20 | 中国科学院南海海洋研究所 | 一类2,5-二酮哌嗪衍生物及其制备方法和在制备抗海洋污损生物防除剂中的应用 |
| US20220064171A1 (en) * | 2018-12-27 | 2022-03-03 | Holosmedic | Novel compound and pharmaceutical composition comprising same for enhancing anticancer activity |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2103479T3 (es) * | 1992-07-10 | 1997-09-16 | Glaxo Lab Sa | Derivados de anilida. |
| WO1994004572A1 (en) * | 1992-08-14 | 1994-03-03 | Torii & Co., Ltd. | Allergenic peptide |
| GB9217331D0 (en) * | 1992-08-14 | 1992-09-30 | Xenova Ltd | Pharmaceutical compounds |
| GB9402807D0 (en) * | 1994-02-14 | 1994-04-06 | Xenova Ltd | Pharmaceutical compounds |
| GB9410387D0 (en) * | 1994-05-24 | 1994-07-13 | Xenova Ltd | Pharmaceutical compounds |
-
1994
- 1994-12-23 GB GBGB9426090.8A patent/GB9426090D0/en active Pending
-
1995
- 1995-12-21 ZA ZA9510908A patent/ZA9510908B/xx unknown
- 1995-12-22 KR KR1019970704226A patent/KR100412167B1/ko not_active IP Right Cessation
- 1995-12-22 DE DE69522342T patent/DE69522342T2/de not_active Expired - Fee Related
- 1995-12-22 UA UA97062956A patent/UA61879C2/uk unknown
- 1995-12-22 CA CA002207548A patent/CA2207548A1/en not_active Abandoned
- 1995-12-22 JP JP8520303A patent/JPH10511385A/ja not_active Ceased
- 1995-12-22 IL IL11652695A patent/IL116526A/xx not_active IP Right Cessation
- 1995-12-22 ES ES95941799T patent/ES2160726T3/es not_active Expired - Lifetime
- 1995-12-22 AT AT95941799T patent/ATE204569T1/de not_active IP Right Cessation
- 1995-12-22 CN CN95197673A patent/CN1108294C/zh not_active Expired - Fee Related
- 1995-12-22 NZ NZ297849A patent/NZ297849A/en unknown
- 1995-12-22 PT PT95941799T patent/PT799210E/pt unknown
- 1995-12-22 US US08/860,328 patent/US5935955A/en not_active Expired - Fee Related
- 1995-12-22 HU HU9800446A patent/HUT77740A/hu unknown
- 1995-12-22 DK DK95941799T patent/DK0799210T3/da active
- 1995-12-22 WO PCT/GB1995/003029 patent/WO1996020180A1/en active IP Right Grant
- 1995-12-22 BR BR9510429A patent/BR9510429A/pt not_active Application Discontinuation
- 1995-12-22 AU AU43102/96A patent/AU700891B2/en not_active Ceased
- 1995-12-22 SK SK835-97A patent/SK283385B6/sk unknown
- 1995-12-22 EP EP95941799A patent/EP0799210B1/en not_active Expired - Lifetime
- 1995-12-22 GB GB9712179A patent/GB2311780B/en not_active Expired - Fee Related
- 1995-12-22 CZ CZ19971902A patent/CZ288935B6/cs not_active IP Right Cessation
- 1995-12-22 PL PL95320915A patent/PL186851B1/pl not_active IP Right Cessation
- 1995-12-23 MY MYPI95004072A patent/MY131762A/en unknown
-
1997
- 1997-06-11 BG BG101601A patent/BG63305B1/bg active Active
- 1997-06-19 FI FI972661A patent/FI972661A/fi not_active IP Right Cessation
- 1997-06-23 NO NO972938A patent/NO308532B1/no not_active IP Right Cessation
-
1998
- 1998-02-11 HK HK98101043A patent/HK1001974A1/xx not_active IP Right Cessation
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