ES2088320T3 - Derivados de carboestirilo. - Google Patents

Derivados de carboestirilo.

Info

Publication number
ES2088320T3
ES2088320T3 ES94914603T ES94914603T ES2088320T3 ES 2088320 T3 ES2088320 T3 ES 2088320T3 ES 94914603 T ES94914603 T ES 94914603T ES 94914603 T ES94914603 T ES 94914603T ES 2088320 T3 ES2088320 T3 ES 2088320T3
Authority
ES
Spain
Prior art keywords
group
pct
derivatives
image
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94914603T
Other languages
English (en)
Inventor
Takao Nishi
Tetsuyuki Uno
Yoshio Shu
Katsumi Tamura
Minoru Okada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2088320T3 publication Critical patent/ES2088320T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

DERIVADOS DEL CARBOESTIRILO REPRESENTADOS POR LA FORMULA GENERAL (1) [EN DONDE R1 ES UN ATOMO DE HIDROGENO, UN ATOMO DE FLUOR, O UN GRUPO METILO; R ES UN GRUPO DE FORMULA (A) (R2 ES UN GRUPO METILO, UN GRUPO TRIFLUOROMETILO O UN GRUPO NITRO), O UN GRUPO DE FORMULA (B) (R3 ES UN ATOMO DE FLUOR Y P ES UN ENTERO, BIEN 2 O 3); Y N ES UN ENTERO, BIEN 2 O 3], O SALES DE LOS MISMOS. DICHOS DERIVADOS DEL CARBOESTIRILO O SALES SON UTILES COMO AGENTES PARA INHIBIR LA ADHESION DE LAS PLAQUETAS.
ES94914603T 1993-05-19 1994-05-11 Derivados de carboestirilo. Expired - Lifetime ES2088320T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11676493 1993-05-19

Publications (1)

Publication Number Publication Date
ES2088320T3 true ES2088320T3 (es) 1996-08-01

Family

ID=14695161

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94914603T Expired - Lifetime ES2088320T3 (es) 1993-05-19 1994-05-11 Derivados de carboestirilo.

Country Status (17)

Country Link
US (1) US5541198A (es)
EP (1) EP0651747B1 (es)
JP (1) JP2742983B2 (es)
KR (1) KR0174111B1 (es)
CN (1) CN1046277C (es)
AT (1) ATE136029T1 (es)
AU (1) AU671026B2 (es)
BR (1) BR1100189A (es)
CA (1) CA2139332A1 (es)
DE (1) DE69400117T2 (es)
DK (1) DK0651747T3 (es)
ES (1) ES2088320T3 (es)
GR (1) GR3020125T3 (es)
HK (1) HK1002705A1 (es)
PH (1) PH30366A (es)
TW (1) TW289019B (es)
WO (1) WO1994026732A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998046593A1 (en) * 1997-04-16 1998-10-22 Otsuka Pharmaceutical Co., Ltd. Novel carbostyril derivative

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57159778A (en) * 1981-03-27 1982-10-01 Otsuka Pharmaceut Co Ltd Carbostyril derivative
DK167187A (da) * 1986-04-02 1987-10-03 Otsuka Pharma Co Ltd Carbostyrilderivater og salte deraf, fremgangsmaade til fremstilling af saadanne forbindelser og laegemiddel indeholdende disse
JPH0681752B2 (ja) * 1986-04-02 1994-10-19 大塚製薬株式会社 カルボスチリル誘導体
JPH0681727B2 (ja) * 1986-04-02 1994-10-19 大塚製薬株式会社 血小板粘着抑制剤

Also Published As

Publication number Publication date
JP2742983B2 (ja) 1998-04-22
US5541198A (en) 1996-07-30
AU6690494A (en) 1994-12-12
GR3020125T3 (en) 1996-08-31
BR1100189A (pt) 2000-08-01
KR0174111B1 (ko) 1999-02-01
PH30366A (en) 1997-04-02
DK0651747T3 (da) 1996-05-20
EP0651747A1 (en) 1995-05-10
AU671026B2 (en) 1996-08-08
TW289019B (es) 1996-10-21
CN1046277C (zh) 1999-11-10
DE69400117T2 (de) 1996-08-22
KR950702552A (ko) 1995-07-29
EP0651747B1 (en) 1996-03-27
CA2139332A1 (en) 1994-11-24
WO1994026732A1 (en) 1994-11-24
CN1110056A (zh) 1995-10-11
HK1002705A1 (en) 1998-09-11
DE69400117D1 (de) 1996-05-02
JPH0733765A (ja) 1995-02-03
ATE136029T1 (de) 1996-04-15

Similar Documents

Publication Publication Date Title
ATE296821T1 (de) Triarylimidazol-derivate als cytokin-inhibitoren
KR960701055A (ko) 인터로이킨-1 및 종양 괴사 인자 억제 활성을 지닌 피라졸로트리아진 (pyrazol itriazines with interleukin-1 and tumour necrosis factor in-hibitory actvity)
AU1180797A (en) Phenylimidazolidines and use thereof as an antiandrogenic agent
DK0677046T3 (da) Piperazinderivater som 5-HT-antagonister.
EE04308B1 (et) Bensimidasooli ühendid, neid ühendeid sisaldavad farmatseutilised kompositsioonid ja nende kasutamine
DK0632805T3 (da) Melaminderivater til anvendelse i behandlingen af cancer
FI951555A0 (fi) 5H,10H-imidatso[1,2-a]indeno[1,2-e]pyratsin-4-onijohdannaiset, niiden valmistus ja niitä sisältävät lääkkeet
DE69719974D1 (de) Chinolinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE69402935D1 (de) Substituierte arylalkylaminobenzyl-aminopropanamide, ihre herstellung und verwendung als antiepileptische, neuroprotektive und antidepressive mittel
ATE167855T1 (de) Propensäure derivate verwendbar als fungizide
DK0689534T3 (da) Amidderivater som 5-HT1A-ligander
NO955328D0 (no) Pyridazin-derivater
ES2088320T3 (es) Derivados de carboestirilo.
ATE191465T1 (de) Carbamoylcarbonsäureamide
DK0544748T3 (da) Spiro cycloalkylbenzen-1, 1-(1,2,3,4-tetrahydroisoquinoliner) med neurobeskyttende egenskaber
MX9605679A (es) 3-fenilpirazoles sustituidos.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 651747

Country of ref document: ES