HK1001974A1 - Pharmaceutical piperazine compounds - Google Patents

Pharmaceutical piperazine compounds

Info

Publication number
HK1001974A1
HK1001974A1 HK98101043A HK98101043A HK1001974A1 HK 1001974 A1 HK1001974 A1 HK 1001974A1 HK 98101043 A HK98101043 A HK 98101043A HK 98101043 A HK98101043 A HK 98101043A HK 1001974 A1 HK1001974 A1 HK 1001974A1
Authority
HK
Hong Kong
Prior art keywords
pct
formula
group
piperazine compounds
sec
Prior art date
Application number
HK98101043A
Other languages
English (en)
Inventor
Philip Anthony Ashworth
Sukhjit Hunjan
Ian Andrew Pretswell
Hamish Ryder
Stephen James Broccini
Original Assignee
Xenova Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenova Ltd filed Critical Xenova Ltd
Publication of HK1001974A1 publication Critical patent/HK1001974A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Electron Tubes For Measurement (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK98101043A 1994-12-23 1998-02-11 Pharmaceutical piperazine compounds HK1001974A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9426090.8A GB9426090D0 (en) 1994-12-23 1994-12-23 Pharmaceutical compounds
PCT/GB1995/003029 WO1996020180A1 (en) 1994-12-23 1995-12-22 Piperazine-2,5-dione derivatives as modulators of multidrug resistance

Publications (1)

Publication Number Publication Date
HK1001974A1 true HK1001974A1 (en) 1998-07-24

Family

ID=10766502

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98101043A HK1001974A1 (en) 1994-12-23 1998-02-11 Pharmaceutical piperazine compounds

Country Status (28)

Country Link
US (1) US5935955A (xx)
EP (1) EP0799210B1 (xx)
JP (1) JPH10511385A (xx)
KR (1) KR100412167B1 (xx)
CN (1) CN1108294C (xx)
AT (1) ATE204569T1 (xx)
AU (1) AU700891B2 (xx)
BG (1) BG63305B1 (xx)
BR (1) BR9510429A (xx)
CA (1) CA2207548A1 (xx)
CZ (1) CZ288935B6 (xx)
DE (1) DE69522342T2 (xx)
DK (1) DK0799210T3 (xx)
ES (1) ES2160726T3 (xx)
FI (1) FI972661A (xx)
GB (2) GB9426090D0 (xx)
HK (1) HK1001974A1 (xx)
HU (1) HUT77740A (xx)
IL (1) IL116526A (xx)
MY (1) MY131762A (xx)
NO (1) NO308532B1 (xx)
NZ (1) NZ297849A (xx)
PL (1) PL186851B1 (xx)
PT (1) PT799210E (xx)
SK (1) SK283385B6 (xx)
UA (1) UA61879C2 (xx)
WO (1) WO1996020180A1 (xx)
ZA (1) ZA9510908B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9708805D0 (en) 1997-05-01 1997-06-25 Smithkline Beecham Plc Compounds
GB9810876D0 (en) 1998-05-20 1998-07-22 Smithkline Beecham Plc Compounds
ES2255311T3 (es) 1998-10-08 2006-06-16 Smithkline Beecham Plc Derivados de tetrahidrobenzazepina utiles como moduladores de los receptores d3 de dopamina (agentes anti-psicoticos).
US6828412B1 (en) * 1999-09-03 2004-12-07 School Of Pharmacy, University Of London Degradable polymers
AU7346400A (en) * 1999-09-03 2001-04-10 School Of Pharmacy, University Of London, The Degradable polymers
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US7220414B2 (en) 2000-09-06 2007-05-22 A.P. Pharma, Inc. Degradable polyacetal polymers
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
BR0213989A (pt) * 2001-11-07 2005-03-01 Pharmacia Corp Métodos para promover a absorção e acúmulo nuclear de poliamidas em células eucarióticas
US8710062B2 (en) * 2011-03-11 2014-04-29 Taipei Medical University Piperazinedione compounds
CN103396372B (zh) * 2013-08-09 2015-05-20 中国科学院南海海洋研究所 一类2,5-二酮哌嗪衍生物及其制备方法和在制备抗海洋污损生物防除剂中的应用
AU2019416623B2 (en) * 2018-12-27 2022-12-08 Holosmedic Novel compound and pharmaceutical composition comprising same for enhancing anticancer activity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994001408A1 (en) * 1992-07-10 1994-01-20 Laboratoires Glaxo S.A. Anilide derivatives
CA2120760A1 (en) * 1992-08-14 1994-03-03 Tohru Ando Peptide having allergenicity
GB9217331D0 (en) * 1992-08-14 1992-09-30 Xenova Ltd Pharmaceutical compounds
GB9402807D0 (en) * 1994-02-14 1994-04-06 Xenova Ltd Pharmaceutical compounds
GB9410387D0 (en) * 1994-05-24 1994-07-13 Xenova Ltd Pharmaceutical compounds

Also Published As

Publication number Publication date
PL320915A1 (en) 1997-11-10
BR9510429A (pt) 1998-07-07
KR100412167B1 (ko) 2004-05-27
GB2311780A (en) 1997-10-08
CA2207548A1 (en) 1996-07-04
SK283385B6 (sk) 2003-06-03
FI972661A (fi) 1997-08-22
GB9712179D0 (en) 1997-08-13
BG63305B1 (bg) 2001-09-28
MY131762A (en) 2007-08-30
FI972661A0 (fi) 1997-06-19
ATE204569T1 (de) 2001-09-15
EP0799210A1 (en) 1997-10-08
ES2160726T3 (es) 2001-11-16
GB9426090D0 (en) 1995-02-22
SK83597A3 (en) 1998-04-08
AU4310296A (en) 1996-07-19
JPH10511385A (ja) 1998-11-04
UA61879C2 (en) 2003-12-15
PL186851B1 (pl) 2004-03-31
IL116526A0 (en) 1996-03-31
DE69522342D1 (de) 2001-09-27
CN1108294C (zh) 2003-05-14
NZ297849A (en) 1999-04-29
NO972938L (no) 1997-06-23
HUT77740A (hu) 1998-07-28
NO308532B1 (no) 2000-09-25
WO1996020180A1 (en) 1996-07-04
CZ288935B6 (cs) 2001-09-12
NO972938D0 (no) 1997-06-23
PT799210E (pt) 2002-01-30
IL116526A (en) 1999-11-30
BG101601A (en) 1998-02-27
AU700891B2 (en) 1999-01-14
ZA9510908B (en) 1996-06-24
US5935955A (en) 1999-08-10
CN1176637A (zh) 1998-03-18
DE69522342T2 (de) 2002-01-03
CZ190297A3 (cs) 1998-01-14
DK0799210T3 (da) 2001-10-01
EP0799210B1 (en) 2001-08-22
GB2311780B (en) 1999-03-03

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20041222