DE69522342D1 - Piperazine-2,5-dione-derivate als multidrugresistenz moldulatoren - Google Patents
Piperazine-2,5-dione-derivate als multidrugresistenz moldulatorenInfo
- Publication number
- DE69522342D1 DE69522342D1 DE69522342T DE69522342T DE69522342D1 DE 69522342 D1 DE69522342 D1 DE 69522342D1 DE 69522342 T DE69522342 T DE 69522342T DE 69522342 T DE69522342 T DE 69522342T DE 69522342 D1 DE69522342 D1 DE 69522342D1
- Authority
- DE
- Germany
- Prior art keywords
- pct
- moldulators
- piperazine
- formula
- multidrug resistant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Electron Tubes For Measurement (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9426090.8A GB9426090D0 (en) | 1994-12-23 | 1994-12-23 | Pharmaceutical compounds |
| PCT/GB1995/003029 WO1996020180A1 (en) | 1994-12-23 | 1995-12-22 | Piperazine-2,5-dione derivatives as modulators of multidrug resistance |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69522342D1 true DE69522342D1 (de) | 2001-09-27 |
| DE69522342T2 DE69522342T2 (de) | 2002-01-03 |
Family
ID=10766502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69522342T Expired - Fee Related DE69522342T2 (de) | 1994-12-23 | 1995-12-22 | Piperazine-2,5-dione-derivate als multidrugresistenz moldulatoren |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5935955A (de) |
| EP (1) | EP0799210B1 (de) |
| JP (1) | JPH10511385A (de) |
| KR (1) | KR100412167B1 (de) |
| CN (1) | CN1108294C (de) |
| AT (1) | ATE204569T1 (de) |
| AU (1) | AU700891B2 (de) |
| BG (1) | BG63305B1 (de) |
| BR (1) | BR9510429A (de) |
| CA (1) | CA2207548A1 (de) |
| CZ (1) | CZ288935B6 (de) |
| DE (1) | DE69522342T2 (de) |
| DK (1) | DK0799210T3 (de) |
| ES (1) | ES2160726T3 (de) |
| FI (1) | FI972661A (de) |
| GB (2) | GB9426090D0 (de) |
| HK (1) | HK1001974A1 (de) |
| HU (1) | HUT77740A (de) |
| IL (1) | IL116526A (de) |
| MY (1) | MY131762A (de) |
| NO (1) | NO308532B1 (de) |
| NZ (1) | NZ297849A (de) |
| PL (1) | PL186851B1 (de) |
| PT (1) | PT799210E (de) |
| SK (1) | SK283385B6 (de) |
| UA (1) | UA61879C2 (de) |
| WO (1) | WO1996020180A1 (de) |
| ZA (1) | ZA9510908B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9708805D0 (en) | 1997-05-01 | 1997-06-25 | Smithkline Beecham Plc | Compounds |
| GB9810876D0 (en) | 1998-05-20 | 1998-07-22 | Smithkline Beecham Plc | Compounds |
| ES2255311T3 (es) | 1998-10-08 | 2006-06-16 | Smithkline Beecham Plc | Derivados de tetrahidrobenzazepina utiles como moduladores de los receptores d3 de dopamina (agentes anti-psicoticos). |
| US6828412B1 (en) * | 1999-09-03 | 2004-12-07 | School Of Pharmacy, University Of London | Degradable polymers |
| AU7346400A (en) * | 1999-09-03 | 2001-04-10 | School Of Pharmacy, University Of London, The | Degradable polymers |
| EP1229934B1 (de) | 1999-10-01 | 2014-03-05 | Immunogen, Inc. | Zusammensetzungen und verfahren zur behandlung von krebs mittels immunkonjugaten und chemotherapeutischen agenzien |
| US7220414B2 (en) | 2000-09-06 | 2007-05-22 | A.P. Pharma, Inc. | Degradable polyacetal polymers |
| US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
| BR0213989A (pt) * | 2001-11-07 | 2005-03-01 | Pharmacia Corp | Métodos para promover a absorção e acúmulo nuclear de poliamidas em células eucarióticas |
| US8710062B2 (en) * | 2011-03-11 | 2014-04-29 | Taipei Medical University | Piperazinedione compounds |
| CN103396372B (zh) * | 2013-08-09 | 2015-05-20 | 中国科学院南海海洋研究所 | 一类2,5-二酮哌嗪衍生物及其制备方法和在制备抗海洋污损生物防除剂中的应用 |
| AU2019416623B2 (en) * | 2018-12-27 | 2022-12-08 | Holosmedic | Novel compound and pharmaceutical composition comprising same for enhancing anticancer activity |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994001408A1 (en) * | 1992-07-10 | 1994-01-20 | Laboratoires Glaxo S.A. | Anilide derivatives |
| CA2120760A1 (en) * | 1992-08-14 | 1994-03-03 | Tohru Ando | Peptide having allergenicity |
| GB9217331D0 (en) * | 1992-08-14 | 1992-09-30 | Xenova Ltd | Pharmaceutical compounds |
| GB9402807D0 (en) * | 1994-02-14 | 1994-04-06 | Xenova Ltd | Pharmaceutical compounds |
| GB9410387D0 (en) * | 1994-05-24 | 1994-07-13 | Xenova Ltd | Pharmaceutical compounds |
-
1994
- 1994-12-23 GB GBGB9426090.8A patent/GB9426090D0/en active Pending
-
1995
- 1995-12-21 ZA ZA9510908A patent/ZA9510908B/xx unknown
- 1995-12-22 PT PT95941799T patent/PT799210E/pt unknown
- 1995-12-22 DK DK95941799T patent/DK0799210T3/da active
- 1995-12-22 UA UA97062956A patent/UA61879C2/uk unknown
- 1995-12-22 DE DE69522342T patent/DE69522342T2/de not_active Expired - Fee Related
- 1995-12-22 ES ES95941799T patent/ES2160726T3/es not_active Expired - Lifetime
- 1995-12-22 PL PL95320915A patent/PL186851B1/pl not_active IP Right Cessation
- 1995-12-22 CN CN95197673A patent/CN1108294C/zh not_active Expired - Fee Related
- 1995-12-22 SK SK835-97A patent/SK283385B6/sk unknown
- 1995-12-22 AT AT95941799T patent/ATE204569T1/de not_active IP Right Cessation
- 1995-12-22 HU HU9800446A patent/HUT77740A/hu unknown
- 1995-12-22 CZ CZ19971902A patent/CZ288935B6/cs not_active IP Right Cessation
- 1995-12-22 BR BR9510429A patent/BR9510429A/pt not_active Application Discontinuation
- 1995-12-22 US US08/860,328 patent/US5935955A/en not_active Expired - Fee Related
- 1995-12-22 CA CA002207548A patent/CA2207548A1/en not_active Abandoned
- 1995-12-22 AU AU43102/96A patent/AU700891B2/en not_active Ceased
- 1995-12-22 GB GB9712179A patent/GB2311780B/en not_active Expired - Fee Related
- 1995-12-22 JP JP8520303A patent/JPH10511385A/ja not_active Ceased
- 1995-12-22 KR KR1019970704226A patent/KR100412167B1/ko not_active IP Right Cessation
- 1995-12-22 WO PCT/GB1995/003029 patent/WO1996020180A1/en active IP Right Grant
- 1995-12-22 EP EP95941799A patent/EP0799210B1/de not_active Expired - Lifetime
- 1995-12-22 IL IL11652695A patent/IL116526A/xx not_active IP Right Cessation
- 1995-12-22 NZ NZ297849A patent/NZ297849A/en unknown
- 1995-12-23 MY MYPI95004072A patent/MY131762A/en unknown
-
1997
- 1997-06-11 BG BG101601A patent/BG63305B1/bg active Active
- 1997-06-19 FI FI972661A patent/FI972661A/fi not_active IP Right Cessation
- 1997-06-23 NO NO972938A patent/NO308532B1/no not_active IP Right Cessation
-
1998
- 1998-02-11 HK HK98101043A patent/HK1001974A1/xx not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |