BG62134B1 - Подобряване поносимостта на фармацевтично активни бета-аминокиселини - Google Patents

Подобряване поносимостта на фармацевтично активни бета-аминокиселини Download PDF

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Publication number
BG62134B1
BG62134B1 BG100716A BG10071696A BG62134B1 BG 62134 B1 BG62134 B1 BG 62134B1 BG 100716 A BG100716 A BG 100716A BG 10071696 A BG10071696 A BG 10071696A BG 62134 B1 BG62134 B1 BG 62134B1
Authority
BG
Bulgaria
Prior art keywords
carbon atoms
group
amino acids
amino acid
cyclopentane
Prior art date
Application number
BG100716A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG100716A (bg
Inventor
Michael Matzke
Hans-Christian Militzer
Joachim Mittendorf
Franz Kunisch
Axel Schmidt
Wolfgang Schoenfeld
Karl Ziegelbauer
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of BG100716A publication Critical patent/BG100716A/bg
Publication of BG62134B1 publication Critical patent/BG62134B1/bg

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/48Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrrole Compounds (AREA)
BG100716A 1995-07-19 1996-07-17 Подобряване поносимостта на фармацевтично активни бета-аминокиселини BG62134B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19526274A DE19526274A1 (de) 1995-07-19 1995-07-19 Verbesserung der Verträglichkeit von pharmazeutisch wirksamen beta-Aminosäuren

Publications (2)

Publication Number Publication Date
BG100716A BG100716A (bg) 1997-04-30
BG62134B1 true BG62134B1 (bg) 1999-03-31

Family

ID=7767189

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100716A BG62134B1 (bg) 1995-07-19 1996-07-17 Подобряване поносимостта на фармацевтично активни бета-аминокиселини

Country Status (45)

Country Link
US (1) US5935988A (cs)
EP (2) EP0754678B1 (cs)
JP (2) JP3891503B2 (cs)
KR (1) KR100433968B1 (cs)
CN (1) CN1115145C (cs)
AR (1) AR003465A1 (cs)
AT (2) ATE344274T1 (cs)
AU (1) AU713555B2 (cs)
BG (1) BG62134B1 (cs)
BR (1) BR9603124A (cs)
CA (1) CA2181308A1 (cs)
CO (1) CO4700525A1 (cs)
CU (1) CU22820A3 (cs)
CZ (2) CZ287896B6 (cs)
DE (3) DE19526274A1 (cs)
DK (2) DK0754678T3 (cs)
DZ (1) DZ2073A1 (cs)
EE (1) EE03803B1 (cs)
ES (2) ES2154761T3 (cs)
GR (1) GR3035601T3 (cs)
HK (1) HK1005131A1 (cs)
HR (1) HRP960303B1 (cs)
HU (1) HUP9601977A3 (cs)
IL (1) IL118869A (cs)
MA (1) MA23940A1 (cs)
MX (1) MX9602836A (cs)
NO (1) NO315926B1 (cs)
NZ (1) NZ299008A (cs)
PE (1) PE9398A1 (cs)
PL (1) PL184861B1 (cs)
PT (2) PT1043332E (cs)
RO (1) RO118656B1 (cs)
RS (1) RS49520B (cs)
RU (1) RU2181123C2 (cs)
SA (1) SA96170491B1 (cs)
SG (1) SG47158A1 (cs)
SI (2) SI1043332T1 (cs)
SK (2) SK284733B6 (cs)
SV (1) SV1996000062A (cs)
TN (1) TNSN96100A1 (cs)
TR (1) TR199600583A2 (cs)
TW (1) TW496737B (cs)
UA (1) UA46725C2 (cs)
YU (1) YU20050685A (cs)
ZA (1) ZA966111B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6191306B1 (en) * 1999-08-03 2001-02-20 Eastman Chemical Company Process for the preparation of cyclopropylglycine
KR20010073441A (ko) * 2000-01-14 2001-08-01 최인도 패류종묘 착상판의 제조방법
US8394813B2 (en) 2000-11-14 2013-03-12 Shire Llc Active agent delivery systems and methods for protecting and administering active agents
US7169752B2 (en) 2003-09-30 2007-01-30 New River Pharmaceuticals Inc. Compounds and compositions for prevention of overdose of oxycodone
US20060014697A1 (en) 2001-08-22 2006-01-19 Travis Mickle Pharmaceutical compositions for prevention of overdose or abuse
US7700561B2 (en) * 2002-02-22 2010-04-20 Shire Llc Abuse-resistant amphetamine prodrugs
US7659253B2 (en) 2002-02-22 2010-02-09 Shire Llc Abuse-resistant amphetamine prodrugs
US7105486B2 (en) * 2002-02-22 2006-09-12 New River Pharmaceuticals Inc. Abuse-resistant amphetamine compounds
AU2004251647B2 (en) * 2003-05-29 2010-01-14 Takeda Pharmaceutical Company Limited Abuse resistant amphetamine compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8716278D0 (en) * 1987-07-10 1987-08-19 Fujisawa Pharmaceutical Co Antimicrobial agent
JPH02174753A (ja) * 1988-08-25 1990-07-06 Fujisawa Pharmaceut Co Ltd シス―2―アミノシクロペンタンカルボン酸誘導体およびその製法ならびに抗菌剤
US5631291A (en) * 1992-05-29 1997-05-20 Bayer Aktiengesellschaft Cyclopentane- and -pentene-β-amino acids
DE4302155A1 (de) * 1993-01-27 1994-07-28 Bayer Ag Verwendung von Cyclopentan- und -penten-beta-Aminosäuren
AU673824B2 (en) * 1992-05-29 1996-11-28 Bayer Aktiengesellschaft Cyclopentane- and -pentene-beta-amino acids
GB9216441D0 (en) * 1992-08-03 1992-09-16 Ici Plc Fungicidal process
WO1995007022A1 (en) * 1993-09-07 1995-03-16 Zeneca Limited Fungicides
DE19548825C2 (de) * 1995-12-27 1999-03-25 Rolf Dr Hermann Neue, substituierte Cyclopentylaminderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE19604225A1 (de) * 1996-02-06 1997-08-07 Bayer Ag Stoffzusammensetzungen aus alpha-Aminosäuren und Cyclohexen-beta-aminosäuren

Also Published As

Publication number Publication date
AU713555B2 (en) 1999-12-02
HK1005131A1 (en) 1998-12-24
RO118656B1 (ro) 2003-08-29
PL315330A1 (en) 1997-01-20
KR970006312A (ko) 1997-02-19
GR3035601T3 (en) 2001-06-29
PT754678E (pt) 2001-04-30
SG47158A1 (en) 1998-03-20
CZ214396A3 (en) 1997-02-12
DE59606266D1 (de) 2001-02-08
DK0754678T3 (da) 2001-02-05
JP3891503B2 (ja) 2007-03-14
MX9602836A (es) 1997-01-31
CZ288204B6 (en) 2001-05-16
PL184861B1 (pl) 2003-01-31
SK94796A3 (en) 1997-02-05
AU5948896A (en) 1997-01-23
HRP960303B1 (en) 2001-08-31
SI0754678T1 (en) 2001-04-30
CU22820A3 (es) 2003-01-29
CZ287896B6 (cs) 2001-03-14
ES2275460T3 (es) 2007-06-16
EE9600109A (et) 1997-02-17
ATE344274T1 (de) 2006-11-15
SK281850B6 (sk) 2001-08-06
JP2007056026A (ja) 2007-03-08
US5935988A (en) 1999-08-10
KR100433968B1 (ko) 2004-08-30
EP1043332A1 (de) 2000-10-11
RU2181123C2 (ru) 2002-04-10
TR199600583A2 (tr) 1997-02-21
CA2181308A1 (en) 1997-01-20
AR003465A1 (es) 1998-08-05
EP0754678A2 (de) 1997-01-22
BR9603124A (pt) 1998-04-22
SI1043332T1 (sl) 2007-04-30
HU9601977D0 (en) 1996-09-30
NO963000L (no) 1997-01-20
CN1115145C (zh) 2003-07-23
DZ2073A1 (fr) 2002-07-22
NO315926B1 (no) 2003-11-17
EP0754678A3 (de) 1997-12-17
HUP9601977A3 (en) 1998-04-28
NO963000D0 (no) 1996-07-18
PT1043332E (pt) 2007-01-31
RS49520B (sr) 2006-10-27
MA23940A1 (fr) 1997-04-01
HUP9601977A2 (en) 1997-05-28
CN1143496A (zh) 1997-02-26
DK1043332T3 (da) 2007-03-12
YU20050685A (sh) 2006-08-17
IL118869A0 (en) 1996-10-31
YU41796A (sh) 1999-06-15
DE19526274A1 (de) 1997-01-23
PE9398A1 (es) 1998-04-15
SV1996000062A (es) 1997-06-26
CO4700525A1 (es) 1998-12-29
SA96170491B1 (ar) 2006-09-20
TNSN96100A1 (fr) 2005-03-15
NZ299008A (en) 1998-05-27
ATE198469T1 (de) 2001-01-15
EP0754678B1 (de) 2001-01-03
EP1043332B1 (de) 2006-11-02
IL118869A (en) 2002-03-10
DE59611398D1 (de) 2006-12-14
TW496737B (en) 2002-08-01
ES2154761T3 (es) 2001-04-16
EE03803B1 (et) 2002-08-15
ZA966111B (en) 1997-02-03
UA46725C2 (uk) 2002-06-17
HRP960303A2 (en) 1998-02-28
BG100716A (bg) 1997-04-30
JPH09202761A (ja) 1997-08-05
SK284733B6 (sk) 2005-10-06

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