BG61080B1 - Модифициран биологичен материал - Google Patents
Модифициран биологичен материал Download PDFInfo
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- BG61080B1 BG61080B1 BG96329A BG9632992A BG61080B1 BG 61080 B1 BG61080 B1 BG 61080B1 BG 96329 A BG96329 A BG 96329A BG 9632992 A BG9632992 A BG 9632992A BG 61080 B1 BG61080 B1 BG 61080B1
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- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/108—Swine
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
- A01K2267/025—Animal producing cells or organs for transplantation
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
Landscapes
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- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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GB898922987A GB8922987D0 (en) | 1989-10-12 | 1989-10-12 | Modified biological material |
GB909017198A GB9017198D0 (en) | 1990-08-06 | 1990-08-06 | Modified biological material |
PCT/GB1990/001575 WO1991005855A1 (en) | 1989-10-12 | 1990-10-12 | Modified biological material |
Publications (2)
Publication Number | Publication Date |
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BG96329A BG96329A (bg) | 1993-12-24 |
BG61080B1 true BG61080B1 (bg) | 1996-10-31 |
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BG96329A BG61080B1 (bg) | 1989-10-12 | 1992-05-12 | Модифициран биологичен материал |
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US (1) | US6495735B1 (hu) |
EP (2) | EP0495852B1 (hu) |
JP (1) | JP3302358B2 (hu) |
KR (2) | KR100317106B1 (hu) |
CN (2) | CN1122719C (hu) |
AT (1) | ATE139562T1 (hu) |
AU (1) | AU654116B2 (hu) |
BG (1) | BG61080B1 (hu) |
CA (1) | CA2067235A1 (hu) |
CY (1) | CY1996A (hu) |
DE (2) | DE69027535T2 (hu) |
DK (1) | DK0495852T3 (hu) |
ES (1) | ES2060561T3 (hu) |
FI (1) | FI921618A0 (hu) |
GR (2) | GR940300004T1 (hu) |
HK (1) | HK48497A (hu) |
HU (1) | HUT64584A (hu) |
IE (1) | IE75345B1 (hu) |
IL (2) | IL95970A0 (hu) |
IN (1) | IN171948B (hu) |
MY (1) | MY107433A (hu) |
NO (2) | NO303502B1 (hu) |
NZ (2) | NZ235657A (hu) |
PT (2) | PT95580B (hu) |
RO (1) | RO109863B1 (hu) |
SG (1) | SG72614A1 (hu) |
WO (1) | WO1991005855A1 (hu) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
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US5705732A (en) * | 1989-06-12 | 1998-01-06 | Oklahoma Medical Research Foundation | Universal donor cells |
EP0483247A4 (en) * | 1989-07-21 | 1992-12-09 | Washington University | Recombinantly produced human membrane cofactor protein (mcp) |
CA2082277A1 (en) * | 1990-05-11 | 1991-11-12 | Damien F. J. Purcell | Cd46 variants |
US5846715A (en) * | 1990-05-11 | 1998-12-08 | The Austin Research Institute | CD46 variants |
ATE237682T1 (de) * | 1991-07-15 | 2003-05-15 | Oklahoma Med Res Found | Universale spenderzellen |
US6916654B1 (en) * | 1992-06-29 | 2005-07-12 | Oklahoma Medical Research Foundation | Universal donor cells |
EP0662125A1 (en) * | 1992-09-22 | 1995-07-12 | Dnx Biotherapeutics, Inc. | Delivery of proteins by intermembrane transfer for preaccommodation of xenogeneic organ transplants and other purposes |
US5627264A (en) * | 1994-03-03 | 1997-05-06 | Alexion Pharmaceuticals, Inc. | Chimeric complement inhibitor proteins |
AU711183B2 (en) * | 1994-08-19 | 1999-10-07 | Biotransplant Incorporated | Genetically engineered swine cells |
AU723003C (en) * | 1995-08-04 | 2004-01-29 | General Hospital Corporation, The | Transgenic swine and swine cells having human HLA genes |
US6166288A (en) * | 1995-09-27 | 2000-12-26 | Nextran Inc. | Method of producing transgenic animals for xenotransplantation expressing both an enzyme masking or reducing the level of the gal epitope and a complement inhibitor |
AU1933897A (en) * | 1996-03-22 | 1997-10-17 | Imutran Limited | Surfaces which prevent or reduce complement activation |
NZ500007A (en) | 1997-03-26 | 2001-08-31 | Imp College Innovations Ltd | Anticoagulant fusion protein anchored to cell membrane to prevent organ rejection after a transplant |
US6825395B1 (en) | 1997-07-14 | 2004-11-30 | Nippon Meat Packers, Inc. | Transgenic non-human mammals expressing the human complement inhibitor (DAF/CD55) |
EP0996461B1 (en) * | 1997-10-31 | 2005-01-12 | Walter Reed Army Institute of Research | Use of a complement activation inhibitor in the manufacture of a medicament for inhibiting side effects of pharmaceutical compositions containing amphiphilic vehicles or drug carrier molecules |
SE523817C2 (sv) | 1999-02-05 | 2004-05-18 | Corline Systems Ab | Användning av ett koagulationsförebyggande ämne i samband med transplantation av insulinproducerande celler |
GB9905503D0 (en) | 1999-03-10 | 1999-05-05 | Adprotech Plc | Novel compound formulations and methods of delivery |
WO2005009134A1 (en) * | 2003-07-21 | 2005-02-03 | Lifecell Corporation | ACELLULAR TISSUE MATRICES MADE FROM GALACTOSE α-1,3-GALACTOSE-DEFICIENT TISSUE |
NZ810903A (en) | 2009-08-14 | 2024-08-30 | Revivicor Inc | Multi-transgenic pigs for diabetes treatment |
US9420770B2 (en) | 2009-12-01 | 2016-08-23 | Indiana University Research & Technology Corporation | Methods of modulating thrombocytopenia and modified transgenic pigs |
NZ608814A (en) | 2010-09-03 | 2015-06-26 | Stem Centrx Inc | Novel modulators and methods of use |
ES2680636T3 (es) | 2011-02-14 | 2018-09-10 | Revivicor Inc. | Cerdos genéticamente modificados para xenotrasplante de xenoinjertos vascularizados y derivados de los mismos |
AU2014341866B2 (en) | 2013-11-04 | 2018-07-05 | Lifecell Corporation | Methods of removing alpha-galactose |
CN114686427B (zh) * | 2022-05-23 | 2022-07-29 | 中国人民解放军总医院第一医学中心 | 一种脾脏调节型b淋巴细胞及其制备方法与应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
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EP0081570A4 (en) * | 1981-06-12 | 1985-09-02 | Univ Ohio | GENETIC TRANSFORMATION OF ZYGOTS. |
US4431636A (en) | 1982-05-24 | 1984-02-14 | American Cyanamid Company | Bis(4-O-polyhexaose-thio)-phenyl ureas and method of use |
US5109113A (en) * | 1986-05-02 | 1992-04-28 | Genentech, Inc. | Membrane anchor fusion polypeptides |
JPS62104594A (ja) * | 1985-10-31 | 1987-05-15 | Terumo Corp | クエン酸塩利用能検査用培地組成物 |
JPH0742235B2 (ja) * | 1985-11-08 | 1995-05-10 | 三共株式会社 | 自己免疫性疾病の予防・治療剤 |
IL82390A0 (en) * | 1986-05-02 | 1987-10-30 | Genentech Inc | Nucleic acid and methods for the synthesis of novel daf compositions |
GB8615942D0 (en) * | 1986-06-30 | 1986-08-06 | Animal & Food Research Council | Peptide production |
IL89790A (en) * | 1988-04-01 | 2002-05-23 | Johns Hopking University | Sequences of nucleic acids encoding and cells producing CR1 protein and methods for its production and purification |
DE3830271A1 (de) | 1988-09-06 | 1990-03-15 | Goetze Otto | Mittel mit immunsuppressiver wirkung |
US5573940A (en) * | 1989-06-12 | 1996-11-12 | Oklahoma Medical Research Foundation | Cells expressing high levels of CD59 |
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1990
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- 1990-10-12 WO PCT/GB1990/001575 patent/WO1991005855A1/en active Application Filing
- 1990-10-12 IN IN872/CAL/90A patent/IN171948B/en unknown
- 1990-10-12 AT AT90915320T patent/ATE139562T1/de not_active IP Right Cessation
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- 1990-10-12 EP EP90915320A patent/EP0495852B1/en not_active Expired - Lifetime
- 1990-10-12 DE DE69027535T patent/DE69027535T2/de not_active Expired - Fee Related
- 1990-10-12 ES ES90915320T patent/ES2060561T3/es not_active Expired - Lifetime
- 1990-10-12 NZ NZ248153A patent/NZ248153A/en unknown
- 1990-10-12 PT PT95580A patent/PT95580B/pt not_active IP Right Cessation
- 1990-10-12 DE DE90915320T patent/DE495852T1/de active Pending
- 1990-10-12 KR KR1019997005897A patent/KR100317106B1/ko not_active IP Right Cessation
- 1990-10-12 IL IL95970A patent/IL95970A0/xx unknown
- 1990-10-12 EP EP95118520A patent/EP0709459A3/en not_active Withdrawn
- 1990-10-12 IE IE364990A patent/IE75345B1/en not_active IP Right Cessation
- 1990-10-12 CN CN90108275A patent/CN1122719C/zh not_active Expired - Fee Related
- 1990-10-12 SG SG1996001903A patent/SG72614A1/en unknown
- 1990-10-12 DK DK90915320.7T patent/DK0495852T3/da active
- 1990-10-12 CA CA002067235A patent/CA2067235A1/en not_active Abandoned
- 1990-10-12 RO RO92-200502A patent/RO109863B1/ro unknown
- 1990-10-12 KR KR1019920700843A patent/KR920702410A/ko not_active Application Discontinuation
- 1990-10-12 CN CNA021302499A patent/CN1491624A/zh active Pending
- 1990-10-12 HU HU9201240A patent/HUT64584A/hu unknown
- 1990-10-12 JP JP51427990A patent/JP3302358B2/ja not_active Ceased
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1992
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1994
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1996
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1997
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1998
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