BG26391A4 - Метод за получаване на субституирани 6-арил-4н-s-триазол- (3,4-с)-тиен-(2,3е)-1,4-диазепини - Google Patents

Метод за получаване на субституирани 6-арил-4н-s-триазол- (3,4-с)-тиен-(2,3е)-1,4-диазепини

Info

Publication number
BG26391A4
BG26391A4 BG030629A BG3062975A BG26391A4 BG 26391 A4 BG26391 A4 BG 26391A4 BG 030629 A BG030629 A BG 030629A BG 3062975 A BG3062975 A BG 3062975A BG 26391 A4 BG26391 A4 BG 26391A4
Authority
BG
Bulgaria
Prior art keywords
diazepines
thiene
triazole
aryl
substituted
Prior art date
Application number
BG030629A
Other languages
Bulgarian (bg)
English (en)
Inventor
Karlheiniz Weber
Adolf Bauer
Peter Danneberg
Franzjosef Kuhn
Original Assignee
C.H.Boehringer Sohn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2410030A external-priority patent/DE2410030C3/de
Priority claimed from DE2435041A external-priority patent/DE2435041C3/de
Priority claimed from DE19742445430 external-priority patent/DE2445430B2/de
Priority claimed from DE2460776A external-priority patent/DE2460776C2/de
Application filed by C.H.Boehringer Sohn filed Critical C.H.Boehringer Sohn
Publication of BG26391A4 publication Critical patent/BG26391A4/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/36—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG030629A 1974-03-02 1975-02-28 Метод за получаване на субституирани 6-арил-4н-s-триазол- (3,4-с)-тиен-(2,3е)-1,4-диазепини BG26391A4 (bg)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE2410030A DE2410030C3 (de) 1974-03-02 1974-03-02 8-Brom-6-phenyl-4H-s-triazolo[3,4-c]thieno[2,3-e]1,4-diazepine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
DE2435041A DE2435041C3 (de) 1974-07-20 1974-07-20 8-Substituierte 6-Aryl-4H-s-triazolo [3,4c] thieno [23e] 1,4-diazepine, Verfahren zu ihrer Herstellung, ihre Verwendung in Arzneimitteln und diese enthaltende pharmazeutische Präparate
DE19742445430 DE2445430B2 (de) 1974-07-20 1974-09-24 1 - substituierte 6-aryl-4h-striazolo eckige klammer auf 3,4c eckige klammer zu thieno-eckige klammer auf 2,3e eckige klammer zu 1,4-diazepine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE2460776A DE2460776C2 (de) 1974-07-20 1974-12-21 1-substituierte 6-Aryl-4H-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Präparate sowie Zwischenprodukte und Verfahren zur Herstellung dieser Zwischenprodukte

Publications (1)

Publication Number Publication Date
BG26391A4 true BG26391A4 (bg) 1979-03-15

Family

ID=27431816

Family Applications (3)

Application Number Title Priority Date Filing Date
BG030629A BG26391A4 (bg) 1974-03-02 1975-02-28 Метод за получаване на субституирани 6-арил-4н-s-триазол- (3,4-с)-тиен-(2,3е)-1,4-диазепини
BG029114A BG26390A3 (bg) 1974-03-02 1975-02-28 Метод за получаване на субституирани 6-арил-4н-s-триазоло-(3,4с) -тиено-(2,3е)-1,4-диазепини
BG030630A BG26392A4 (bg) 1974-03-02 1975-02-28 Метод за получаване на заместени 6-арил-4н-сим.-триазоло-(3,4с) -тиено-(2,3-е)-1,4-диазепини

Family Applications After (2)

Application Number Title Priority Date Filing Date
BG029114A BG26390A3 (bg) 1974-03-02 1975-02-28 Метод за получаване на субституирани 6-арил-4н-s-триазоло-(3,4с) -тиено-(2,3е)-1,4-диазепини
BG030630A BG26392A4 (bg) 1974-03-02 1975-02-28 Метод за получаване на заместени 6-арил-4н-сим.-триазоло-(3,4с) -тиено-(2,3-е)-1,4-диазепини

Country Status (24)

Country Link
US (2) US4094984A (es)
JP (1) JPS5930713B2 (es)
AT (1) AT338799B (es)
BE (1) BE826179A (es)
BG (3) BG26391A4 (es)
CA (1) CA1073904A (es)
CH (1) CH611900A5 (es)
CS (1) CS203083B2 (es)
DD (1) DD120022A5 (es)
DK (1) DK141876C (es)
ES (2) ES435223A1 (es)
FI (1) FI59099C (es)
FR (3) FR2262525B1 (es)
GB (1) GB1497527A (es)
IE (1) IE42737B1 (es)
IL (1) IL52138A0 (es)
NL (2) NL163515C (es)
NO (1) NO140671C (es)
PH (2) PH15360A (es)
PL (2) PL96223B1 (es)
RO (3) RO66909A (es)
SE (1) SE421794B (es)
SU (2) SU583758A3 (es)
YU (3) YU39732B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT338799B (de) * 1974-03-02 1977-09-12 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer substituierter 6-aryl-4h-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine und ihrer salze
AT358049B (de) * 1977-01-27 1980-08-11 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer 1-substi- tuierter 8-jod-6-phenyl-4h-s-triazolo(3,4c) thieno(2,3e)1,4-diazepine und deren salzen
DE2708121A1 (de) * 1977-02-25 1978-09-07 Boehringer Sohn Ingelheim Triazolo-thieno-diazepin-l-one, verfahren zu ihrer herstellung und arzneimittel
FI63033C (fi) * 1977-07-21 1983-04-11 Boehringer Sohn Ingelheim Foerfarande foer framstaellning av anxiolytiska tranquilliserande sedativa och/eller neuroleptiska substituerade 1-piperazinyl-4h-s-triazolo(3,4-c)tieno(2,3-e)-1,4-diazepiner
DE2830782A1 (de) * 1978-07-13 1980-01-24 Boehringer Sohn Ingelheim Neue substituierte 4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4-diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
DE3777541D1 (de) * 1986-11-17 1992-04-23 Yoshitomi Pharmaceutical Paf-antagonistische thienotriazoldiazepin-verbindungen und deren pharmazeutische anwendung.
US4959361A (en) * 1987-12-18 1990-09-25 Hoffmann-La Roche Inc. Triazolo(4,3-A)(1,4)benzodiazepines and thieno (3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine compounds which have useful activity as platelet activating factor (PAF) antagonists
DE4010528A1 (de) * 1990-04-02 1991-10-17 Boehringer Ingelheim Kg Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine
WO1995032963A1 (fr) * 1994-06-01 1995-12-07 Yoshitomi Pharmaceutical Industries, Ltd. Compose de thienylazole et compose de thienotriazolodiazepine
US5552399A (en) * 1994-11-02 1996-09-03 Janssen Pharmaceutica N.V. Substituted tetracyclic azepine derivatives
KR100642024B1 (ko) 1998-06-09 2006-11-06 다케다 야쿠힌 고교 가부시키가이샤 수면 장애를 치료 또는 예방하기 위한 약학적 조성물
US6884886B2 (en) * 2001-04-04 2005-04-26 Boehringer Ingelheim Pharma Kg Process for preparing 6-aryl-4H-S-triazolo[3,4-c]-thieno[2,3-e]-1,4-diazepines
DE10116378C2 (de) * 2001-04-04 2003-05-28 Boehringer Ingelheim Pharma Verfahren zur Herstellung von 6-Aryl-4H-s-triazolo[3,4-c]-thieno[2,3-e]-1,4-diazepinen
CN106397452A (zh) * 2016-07-26 2017-02-15 江苏兢业制药有限公司 7‑溴‑5‑(2‑氯苯基)‑1,3‑二氢噻吩并[2,3e]‑1,4‑二氮杂卓‑2‑硫酮的制备方法
JP6843811B2 (ja) 2018-09-19 2021-03-17 岬環境プラン株式会社 撒積貨物船の船艙壁面清掃装置

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3709899A (en) * 1971-04-28 1973-01-09 Upjohn Co 6-phenyl-4h-s-triazolo(4,3-a)(1,4)benzodiazepines and their production
US3751426A (en) * 1971-04-28 1973-08-07 Upjohn Co 1-substituted-6-phenyl-4h-s-triazolo(4,3-a)(1,6)benzodiazepine compounds
US3849934A (en) * 1971-05-03 1974-11-26 Scm Corp Alpha-aryl-n-lower alkyl nitrone-containing compositions useful as anti-fungal agents
US3856802A (en) * 1971-05-10 1974-12-24 Upjohn Co 1,6-DISUBSTITUTED-4H-5-{8 4,3-a{9 BENZODIAZEPINES
GB1323277A (en) * 1971-05-10 1973-07-11 Upjohn Co Triazolobenzodiazepines
US3681343A (en) * 1971-05-11 1972-08-01 Upjohn Co 6-phenyl-s-triazolo{8 4,3-a{9 {8 1,4{9 {0 benzodiazepines
US3904641A (en) * 1971-06-18 1975-09-09 Yoshitomi Pharmaceutical Triazolothienodiazepine compounds
GB1332766A (en) * 1971-06-18 1973-10-03 Upjohn Co Triazolo-benzodiazepines
GB1377230A (en) * 1971-09-13 1974-12-11 Upjohn Co 4h-s-triazolo -4,3-a- 1,4-benzodiazepines
US3767660A (en) * 1971-09-13 1973-10-23 Upjohn Co 4h-s-triazolo(4,3-a)(1,4)benzodiazepines
GB1387783A (en) * 1972-08-08 1975-03-19 Yoshitomi Pharmaceutical Thiophene derivatives, method for their preparation and pharmaceutical composition thereof
PH12303A (en) * 1973-02-08 1979-01-16 Hoffmann La Roche Thienotriazolodiazepine derivatives
AT338799B (de) * 1974-03-02 1977-09-12 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer substituierter 6-aryl-4h-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine und ihrer salze

Also Published As

Publication number Publication date
NL163515C (nl) 1980-09-15
US4094984A (en) 1978-06-13
AT338799B (de) 1977-09-12
JPS5180899A (en) 1976-07-15
DD120022A5 (es) 1976-05-20
RO71261A (ro) 1983-04-29
FR2287449B1 (es) 1979-06-22
IE42737B1 (en) 1980-10-08
FR2262525A1 (es) 1975-09-26
US4199588A (en) 1980-04-22
SU583758A3 (ru) 1977-12-05
NO140671B (no) 1979-07-09
IE42737L (en) 1975-09-02
PH15360A (en) 1982-12-10
SU648104A3 (ru) 1979-02-15
NL930123I1 (nl) 1993-11-01
BG26390A3 (bg) 1979-03-15
YU102582A (en) 1982-08-31
YU102482A (en) 1982-08-31
SE421794B (sv) 1982-02-01
RO71260B (ro) 1983-04-30
DK141876C (da) 1980-11-17
YU47775A (en) 1982-08-31
NO140671C (no) 1979-10-17
FI750592A (es) 1975-09-03
FI59099B (fi) 1981-02-27
FR2361398B1 (es) 1980-09-12
NL7502391A (nl) 1975-09-04
RO71261B (ro) 1983-04-30
NO750691L (es) 1975-09-03
ATA108975A (de) 1977-01-15
FR2287449A1 (fr) 1976-05-07
DK80775A (es) 1975-09-03
CH611900A5 (es) 1979-06-29
PL96223B1 (pl) 1977-12-31
ES435223A1 (es) 1977-05-01
CS203083B2 (en) 1981-02-27
YU39891B (en) 1985-04-30
PH15120A (en) 1982-08-10
ES437261A1 (es) 1977-04-01
RO71260A (ro) 1983-04-29
FR2361398A1 (fr) 1978-03-10
RO66909A (ro) 1981-03-21
JPS5930713B2 (ja) 1984-07-28
SE7502313L (es) 1975-09-03
PL99177B1 (pl) 1978-06-30
YU39890B (en) 1985-04-30
YU39732B (en) 1985-04-30
FI59099C (fi) 1981-06-10
GB1497527A (en) 1978-01-12
DK141876B (da) 1980-07-07
CA1073904A (en) 1980-03-18
NL163515B (nl) 1980-04-15
BE826179A (fr) 1975-08-28
BG26392A4 (bg) 1979-03-15
FR2262525B1 (es) 1978-08-18
IL52138A0 (en) 1977-07-31

Similar Documents

Publication Publication Date Title
BG26192A3 (bg) Метод за получаване на 3-арилокси-3-фенилпропиламини
RO75006A (ro) Procedeu pentru prepararea unor mercaptoazetidinone
BG26391A4 (bg) Метод за получаване на субституирани 6-арил-4н-s-триазол- (3,4-с)-тиен-(2,3е)-1,4-диазепини
SE420492B (sv) Forfarande for framstellning av 1,1-diaryl-1-oxadiazol-alkylaminer
BG27542A3 (bg) Метод за получаване на 1-бензазолилалкил-4-заместени пиперидини
BG24539A3 (bg) Метод за получаване на 1-етил- за- субституирани - фенил - декахидроизохинолини
IL46467A (en) 1-n-derivatives of 4,6-di-(amino-glycosyl)-1,3-diaminocylitols and method for their preparation
RO73017A (ro) Procedeu pentru prepararea unor indolenine substituite
BG27084A3 (bg) Метод за получаване на 2-карбалкоксиамино-5 (6) -фенил-сулфонилокси-бензимидазоли
RO65456A (ro) Procedeu pentru prepararea unor 6-metil-8-metilergoline substituite
RO69281A (ro) Procedeu pentru prepararea alchilamino-s-triazinelor
SE433210B (sv) Forfarande for framstellning av ny cyklohexylfenylderivat
RO70076A (ro) Procedeu pentru prepararea unor 4,4-diaril-2-hidroxibutilamine
SE417092B (sv) Forfarande for framstellning av 1,2,3,4-tetrahydroisokinoliner
SU589926A3 (ru) Способ получени дауномицинов
BG22387A3 (bg) Метод за получаване на n,n-диалилдихлорацетамид
RO74273A (ro) Procedeu pentru prepararea unor sulfinilazetidinone
RO71797A (ro) Procedeu pentru prepararea unor tiocarbamati s-alchil substituiti
BG27083A3 (bg) Метод за получаване на заместени 1-сулфонилбензимидазоли
SE423992B (sv) Forfarande for framstellning av 9, 11, 15-trihydroxi-13, 14-dehydroprostaglandiner
SE7613545L (sv) Sett att framstella difluormetyl-1,2,2-triflnoretyleter
SE420600B (sv) Forfarande for framstellning av 1,2,3,4-tetrahydroisokinoliner
SE417963B (sv) Forfarande for framstellning av metyl-6-n-propoxibensotiazol-2-karbamat
SE438506B (sv) Forfarande for framstellning av 5,6-dehydropenicilliner
SE7604321L (sv) Forfarande for framstellning av 3,3,4,4-tetraklortetrahydrotiofen-1,1-dioxid