NL7502391A - Nieuwe gesubstitueerde 6-aryl-4h-s-triazolo- -(3,4c)-thieno (2,3e)-1,4-diazepinen en werk- wijze voor de bereiding daarvan. - Google Patents
Nieuwe gesubstitueerde 6-aryl-4h-s-triazolo- -(3,4c)-thieno (2,3e)-1,4-diazepinen en werk- wijze voor de bereiding daarvan.Info
- Publication number
- NL7502391A NL7502391A NL7502391A NL7502391A NL7502391A NL 7502391 A NL7502391 A NL 7502391A NL 7502391 A NL7502391 A NL 7502391A NL 7502391 A NL7502391 A NL 7502391A NL 7502391 A NL7502391 A NL 7502391A
- Authority
- NL
- Netherlands
- Prior art keywords
- diazepines
- thieno
- triazolo
- aryl
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2410030A DE2410030C3 (de) | 1974-03-02 | 1974-03-02 | 8-Brom-6-phenyl-4H-s-triazolo[3,4-c]thieno[2,3-e]1,4-diazepine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen |
DE2435041A DE2435041C3 (de) | 1974-07-20 | 1974-07-20 | 8-Substituierte 6-Aryl-4H-s-triazolo [3,4c] thieno [23e] 1,4-diazepine, Verfahren zu ihrer Herstellung, ihre Verwendung in Arzneimitteln und diese enthaltende pharmazeutische Präparate |
DE19742445430 DE2445430B2 (de) | 1974-07-20 | 1974-09-24 | 1 - substituierte 6-aryl-4h-striazolo eckige klammer auf 3,4c eckige klammer zu thieno-eckige klammer auf 2,3e eckige klammer zu 1,4-diazepine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
DE2460776A DE2460776C2 (de) | 1974-07-20 | 1974-12-21 | 1-substituierte 6-Aryl-4H-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Präparate sowie Zwischenprodukte und Verfahren zur Herstellung dieser Zwischenprodukte |
Publications (3)
Publication Number | Publication Date |
---|---|
NL7502391A true NL7502391A (nl) | 1975-09-04 |
NL163515B NL163515B (nl) | 1980-04-15 |
NL163515C NL163515C (nl) | 1980-09-15 |
Family
ID=27431816
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL7502391.A NL163515C (nl) | 1974-03-02 | 1975-02-28 | Werkwijze voor het bereiden van een farmaceutisch preparaat alsmede voor het bereiden van een daarin als werkzaam bestanddeel aanwezig, gesubstitueerd 6-aryl-4h-s- triazolo-3,4c-thieno-2,3e-1,4- -diazepine. |
NL930123C NL930123I1 (nl) | 1974-03-02 | 1993-06-30 | Werkwijze voor het bereiden van een farmaceutisch preparaat alsmede voor het bereiden van een daari n als werkzaam bestanddeel aanwezig gesubstitueerd6-aryl-4H-s-triazolo-[3,4c]-thieno-[2,3e]-1,4-dia zepine |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL930123C NL930123I1 (nl) | 1974-03-02 | 1993-06-30 | Werkwijze voor het bereiden van een farmaceutisch preparaat alsmede voor het bereiden van een daari n als werkzaam bestanddeel aanwezig gesubstitueerd6-aryl-4H-s-triazolo-[3,4c]-thieno-[2,3e]-1,4-dia zepine |
Country Status (24)
Country | Link |
---|---|
US (2) | US4094984A (nl) |
JP (1) | JPS5930713B2 (nl) |
AT (1) | AT338799B (nl) |
BE (1) | BE826179A (nl) |
BG (3) | BG26392A4 (nl) |
CA (1) | CA1073904A (nl) |
CH (1) | CH611900A5 (nl) |
CS (1) | CS203083B2 (nl) |
DD (1) | DD120022A5 (nl) |
DK (1) | DK141876C (nl) |
ES (2) | ES435223A1 (nl) |
FI (1) | FI59099C (nl) |
FR (3) | FR2262525B1 (nl) |
GB (1) | GB1497527A (nl) |
IE (1) | IE42737B1 (nl) |
IL (1) | IL52138A0 (nl) |
NL (2) | NL163515C (nl) |
NO (1) | NO140671C (nl) |
PH (2) | PH15360A (nl) |
PL (2) | PL99177B1 (nl) |
RO (3) | RO71261B (nl) |
SE (1) | SE421794B (nl) |
SU (2) | SU583758A3 (nl) |
YU (3) | YU39732B (nl) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4333944A (en) * | 1977-02-25 | 1982-06-08 | Boehringer Ingelheim Gmbh | 8-Halo-6-phenyl-4H-s-triazolo (3,4-c) thieno 1,4-diazepin-1-ones |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT338799B (de) * | 1974-03-02 | 1977-09-12 | Boehringer Sohn Ingelheim | Verfahren zur herstellung neuer substituierter 6-aryl-4h-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine und ihrer salze |
AT358049B (de) * | 1977-01-27 | 1980-08-11 | Boehringer Sohn Ingelheim | Verfahren zur herstellung neuer 1-substi- tuierter 8-jod-6-phenyl-4h-s-triazolo(3,4c) thieno(2,3e)1,4-diazepine und deren salzen |
FI63033C (fi) * | 1977-07-21 | 1983-04-11 | Boehringer Sohn Ingelheim | Foerfarande foer framstaellning av anxiolytiska tranquilliserande sedativa och/eller neuroleptiska substituerade 1-piperazinyl-4h-s-triazolo(3,4-c)tieno(2,3-e)-1,4-diazepiner |
DE2830782A1 (de) * | 1978-07-13 | 1980-01-24 | Boehringer Sohn Ingelheim | Neue substituierte 4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4-diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen |
PH30676A (en) * | 1986-07-22 | 1997-09-16 | Boehringer Ingelhein Kg | Hetrazepine compounds which have useful pharmaceutical utility |
EP0268242B1 (en) * | 1986-11-17 | 1992-03-18 | Yoshitomi Pharmaceutical Industries, Ltd. | Paf-antagonistic thienotriazolodiazepine compounds and pharmaceutical uses thereof |
US4959361A (en) * | 1987-12-18 | 1990-09-25 | Hoffmann-La Roche Inc. | Triazolo(4,3-A)(1,4)benzodiazepines and thieno (3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine compounds which have useful activity as platelet activating factor (PAF) antagonists |
DE4010528A1 (de) * | 1990-04-02 | 1991-10-17 | Boehringer Ingelheim Kg | Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine |
WO1995032963A1 (fr) * | 1994-06-01 | 1995-12-07 | Yoshitomi Pharmaceutical Industries, Ltd. | Compose de thienylazole et compose de thienotriazolodiazepine |
US5552399A (en) * | 1994-11-02 | 1996-09-03 | Janssen Pharmaceutica N.V. | Substituted tetracyclic azepine derivatives |
ATE247967T1 (de) | 1998-06-09 | 2003-09-15 | Takeda Chemical Industries Ltd | Pharmazeutische kombination mit einem trizyclischen komponent und mindestens einem aus zolpidem, zopiclone und brotizolam, zur behandlung von schlafstörungen |
DE10116378C2 (de) * | 2001-04-04 | 2003-05-28 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von 6-Aryl-4H-s-triazolo[3,4-c]-thieno[2,3-e]-1,4-diazepinen |
US6884886B2 (en) * | 2001-04-04 | 2005-04-26 | Boehringer Ingelheim Pharma Kg | Process for preparing 6-aryl-4H-S-triazolo[3,4-c]-thieno[2,3-e]-1,4-diazepines |
CN106397452A (zh) * | 2016-07-26 | 2017-02-15 | 江苏兢业制药有限公司 | 7‑溴‑5‑(2‑氯苯基)‑1,3‑二氢噻吩并[2,3e]‑1,4‑二氮杂卓‑2‑硫酮的制备方法 |
JP6843811B2 (ja) | 2018-09-19 | 2021-03-17 | 岬環境プラン株式会社 | 撒積貨物船の船艙壁面清掃装置 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3709899A (en) * | 1971-04-28 | 1973-01-09 | Upjohn Co | 6-phenyl-4h-s-triazolo(4,3-a)(1,4)benzodiazepines and their production |
US3751426A (en) * | 1971-04-28 | 1973-08-07 | Upjohn Co | 1-substituted-6-phenyl-4h-s-triazolo(4,3-a)(1,6)benzodiazepine compounds |
US3849934A (en) * | 1971-05-03 | 1974-11-26 | Scm Corp | Alpha-aryl-n-lower alkyl nitrone-containing compositions useful as anti-fungal agents |
GB1323277A (en) * | 1971-05-10 | 1973-07-11 | Upjohn Co | Triazolobenzodiazepines |
US3856802A (en) * | 1971-05-10 | 1974-12-24 | Upjohn Co | 1,6-DISUBSTITUTED-4H-5-{8 4,3-a{9 BENZODIAZEPINES |
US3681343A (en) | 1971-05-11 | 1972-08-01 | Upjohn Co | 6-phenyl-s-triazolo{8 4,3-a{9 {8 1,4{9 {0 benzodiazepines |
GB1332766A (en) * | 1971-06-18 | 1973-10-03 | Upjohn Co | Triazolo-benzodiazepines |
US3904641A (en) * | 1971-06-18 | 1975-09-09 | Yoshitomi Pharmaceutical | Triazolothienodiazepine compounds |
GB1377230A (en) * | 1971-09-13 | 1974-12-11 | Upjohn Co | 4h-s-triazolo -4,3-a- 1,4-benzodiazepines |
US3767660A (en) * | 1971-09-13 | 1973-10-23 | Upjohn Co | 4h-s-triazolo(4,3-a)(1,4)benzodiazepines |
GB1387783A (en) * | 1972-08-08 | 1975-03-19 | Yoshitomi Pharmaceutical | Thiophene derivatives, method for their preparation and pharmaceutical composition thereof |
PH12303A (en) * | 1973-02-08 | 1979-01-16 | Hoffmann La Roche | Thienotriazolodiazepine derivatives |
AT338799B (de) * | 1974-03-02 | 1977-09-12 | Boehringer Sohn Ingelheim | Verfahren zur herstellung neuer substituierter 6-aryl-4h-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine und ihrer salze |
-
1975
- 1975-02-14 AT AT108975A patent/AT338799B/de not_active IP Right Cessation
- 1975-02-25 SU SU7502112490A patent/SU583758A3/ru active
- 1975-02-26 CS CS751284A patent/CS203083B2/cs unknown
- 1975-02-27 YU YU477/75A patent/YU39732B/xx unknown
- 1975-02-27 IE IE422/75A patent/IE42737B1/en unknown
- 1975-02-27 CH CH251075A patent/CH611900A5/xx not_active IP Right Cessation
- 1975-02-28 SE SE7502313A patent/SE421794B/xx not_active IP Right Cessation
- 1975-02-28 DK DK80775A patent/DK141876C/da active
- 1975-02-28 BE BE153916A patent/BE826179A/xx not_active IP Right Cessation
- 1975-02-28 RO RO90413A patent/RO71261B/ro unknown
- 1975-02-28 BG BG030630A patent/BG26392A4/xx unknown
- 1975-02-28 FR FR7506414A patent/FR2262525B1/fr not_active Expired
- 1975-02-28 DD DD184500A patent/DD120022A5/xx unknown
- 1975-02-28 RO RO90412A patent/RO71260B/ro unknown
- 1975-02-28 BG BG030629A patent/BG26391A4/xx unknown
- 1975-02-28 BG BG029114A patent/BG26390A3/xx unknown
- 1975-02-28 NL NL7502391.A patent/NL163515C/nl active Protection Beyond IP Right Term
- 1975-02-28 JP JP50025531A patent/JPS5930713B2/ja not_active Expired
- 1975-02-28 FI FI750592A patent/FI59099C/fi not_active IP Right Cessation
- 1975-02-28 RO RO7581529A patent/RO66909A/ro unknown
- 1975-02-28 NO NO750691A patent/NO140671C/no unknown
- 1975-03-01 PL PL1975195734A patent/PL99177B1/pl unknown
- 1975-03-01 PL PL1975178420A patent/PL96223B1/pl unknown
- 1975-03-01 ES ES435223A patent/ES435223A1/es not_active Expired
- 1975-03-03 PH PH16964A patent/PH15360A/en unknown
- 1975-03-03 GB GB27236/77A patent/GB1497527A/en not_active Expired
- 1975-04-30 ES ES437261A patent/ES437261A1/es not_active Expired
- 1975-08-27 SU SU752167354A patent/SU648104A3/ru active
-
1976
- 1976-01-21 FR FR7601563A patent/FR2287449A1/fr active Granted
-
1977
- 1977-05-20 IL IL52138A patent/IL52138A0/xx unknown
- 1977-09-30 FR FR7729531A patent/FR2361398A1/fr active Granted
- 1977-10-06 US US05/839,792 patent/US4094984A/en not_active Expired - Lifetime
- 1977-11-30 US US05/855,753 patent/US4199588A/en not_active Expired - Lifetime
-
1978
- 1978-10-31 CA CA315,113A patent/CA1073904A/en not_active Expired
-
1980
- 1980-04-23 PH PH23939A patent/PH15120A/en unknown
-
1982
- 1982-05-13 YU YU1024/82A patent/YU39890B/xx unknown
- 1982-05-13 YU YU1025/82A patent/YU39891B/xx unknown
-
1993
- 1993-06-30 NL NL930123C patent/NL930123I1/nl unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4333944A (en) * | 1977-02-25 | 1982-06-08 | Boehringer Ingelheim Gmbh | 8-Halo-6-phenyl-4H-s-triazolo (3,4-c) thieno 1,4-diazepin-1-ones |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
V4 | Discontinued because of reaching the maximum lifetime of a patent | ||
BC1 | Further communications concerning applications for a supplementary protection certificate |
Free format text: 930123 |