BG24668A3 - Method of preparing isobutyl ester of 2,6-dimeth l-3-methoxycarbonyl-4-(2-nitrophenyl)-1,4-dihydropyridi e-5-ca-boxylic acid - Google Patents

Method of preparing isobutyl ester of 2,6-dimeth l-3-methoxycarbonyl-4-(2-nitrophenyl)-1,4-dihydropyridi e-5-ca-boxylic acid

Info

Publication number
BG24668A3
BG24668A3 BG7600034575A BG3457576A BG24668A3 BG 24668 A3 BG24668 A3 BG 24668A3 BG 7600034575 A BG7600034575 A BG 7600034575A BG 3457576 A BG3457576 A BG 3457576A BG 24668 A3 BG24668 A3 BG 24668A3
Authority
BG
Bulgaria
Prior art keywords
dihydropyridi
dimeth
methoxycarbonyl
nitrophenyl
isobutyl ester
Prior art date
Application number
BG7600034575A
Other languages
Bulgarian (bg)
English (en)
Inventor
Wehinger
Bossert
Heise
Kazda
Stoepel
Vater
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BG24668A3 publication Critical patent/BG24668A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG7600034575A 1975-11-05 1976-11-01 Method of preparing isobutyl ester of 2,6-dimeth l-3-methoxycarbonyl-4-(2-nitrophenyl)-1,4-dihydropyridi e-5-ca-boxylic acid BG24668A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2549568A DE2549568C3 (de) 1975-11-05 1975-11-05 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
BG24668A3 true BG24668A3 (en) 1978-04-12

Family

ID=5960951

Family Applications (6)

Application Number Title Priority Date Filing Date
BG7600035341A BG25078A3 (en) 1975-11-05 1976-11-01 A method of obtaining isobutyl ester of 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid
BG7600035343A BG24803A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG7600035345A BG24805A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG7600035342A BG25079A3 (en) 1975-11-05 1976-11-01 A method of obtaining isobutyl ester ob 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid
BG7600034575A BG24668A3 (en) 1975-11-05 1976-11-01 Method of preparing isobutyl ester of 2,6-dimeth l-3-methoxycarbonyl-4-(2-nitrophenyl)-1,4-dihydropyridi e-5-ca-boxylic acid
BG7600035344A BG24804A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridiny-5-carboxylic acid

Family Applications Before (4)

Application Number Title Priority Date Filing Date
BG7600035341A BG25078A3 (en) 1975-11-05 1976-11-01 A method of obtaining isobutyl ester of 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid
BG7600035343A BG24803A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG7600035345A BG24805A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridine-5-carboxylic acid
BG7600035342A BG25079A3 (en) 1975-11-05 1976-11-01 A method of obtaining isobutyl ester ob 2,6-dimethyl-3-metoxycarbonyl-4-(2'-nitrophenyl)-1,4-dichidropiridin-5-carbonic acid

Family Applications After (1)

Application Number Title Priority Date Filing Date
BG7600035344A BG24804A3 (en) 1975-11-05 1976-11-01 Method of obtaining isobutyl ester of 2,6-dimethyl-3-methoxycarbonyl-4-(2'-nitrophenyl)-1,4-dihydropyridiny-5-carboxylic acid

Country Status (27)

Country Link
JP (1) JPS5259161A (no)
AT (1) AT352129B (no)
AU (1) AU498964B2 (no)
BE (1) BE847968A (no)
BG (6) BG25078A3 (no)
CA (1) CA1085406A (no)
CH (2) CH623038A5 (no)
CS (1) CS200499B2 (no)
DE (1) DE2549568C3 (no)
DK (1) DK146762C (no)
ES (2) ES452986A1 (no)
FI (1) FI60704C (no)
FR (1) FR2330395A1 (no)
GB (1) GB1516793A (no)
GR (1) GR61241B (no)
HK (1) HK12681A (no)
IE (1) IE43984B1 (no)
IL (1) IL50817A (no)
LU (2) LU88275I2 (no)
NL (2) NL175915C (no)
NO (1) NO145574C (no)
NZ (1) NZ182502A (no)
PL (2) PL106084B1 (no)
PT (1) PT65797B (no)
RO (1) RO70295A (no)
SE (1) SE423542B (no)
ZA (1) ZA766622B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE3212736A1 (de) * 1982-04-06 1983-10-13 Bayer Ag, 5090 Leverkusen Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
JPS5982192U (ja) * 1982-11-27 1984-06-02 エムケ−精工株式会社 扉
DE3312216A1 (de) * 1983-04-05 1984-10-11 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3312283A1 (de) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
DE2549568A1 (de) 1977-05-18
DK146762C (da) 1984-06-12
CH623038A5 (en) 1981-05-15
NL930035I2 (nl) 1993-10-01
SE423542B (sv) 1982-05-10
DE2549568B2 (de) 1980-08-21
BG25078A3 (en) 1978-07-12
BG24805A3 (en) 1978-05-12
AU498964B2 (en) 1979-03-29
ES452986A1 (es) 1977-12-16
FI60704B (fi) 1981-11-30
GB1516793A (en) 1978-07-05
SE7612308L (sv) 1977-05-06
BG25079A3 (en) 1978-07-12
LU76133A1 (no) 1977-06-02
CH622779A5 (en) 1981-04-30
JPS5259161A (en) 1977-05-16
BG24804A3 (en) 1978-05-12
CS200499B2 (en) 1980-09-15
PT65797B (de) 1978-05-12
BG24803A3 (en) 1978-05-12
PL105940B1 (pl) 1979-11-30
AU1935876A (en) 1978-05-11
NO145574C (no) 1982-04-21
NZ182502A (en) 1978-07-28
DK146762B (da) 1983-12-27
IE43984B1 (en) 1981-07-15
LU88275I2 (no) 1994-02-03
CA1085406A (en) 1980-09-09
GR61241B (en) 1978-10-12
NL930035I1 (nl) 1993-08-02
DK498476A (da) 1977-05-06
NL7612198A (nl) 1977-05-09
ZA766622B (en) 1977-10-26
PL106084B1 (pl) 1979-11-30
FR2330395B1 (no) 1978-12-22
PT65797A (de) 1976-12-01
NO763608L (no) 1977-05-06
DE2549568C3 (de) 1981-10-29
AT352129B (de) 1979-09-10
ES463166A1 (es) 1978-07-16
NO145574B (no) 1982-01-11
HK12681A (en) 1981-04-10
BE847968A (fr) 1977-05-04
IL50817A0 (en) 1977-01-31
ATA814276A (de) 1979-02-15
IE43984L (en) 1977-05-05
NL175915C (nl) 1985-01-16
IL50817A (en) 1979-07-25
FR2330395A1 (fr) 1977-06-03
JPS5647185B2 (no) 1981-11-07
RO70295A (ro) 1981-08-17
FI60704C (fi) 1982-03-10
FI763160A (no) 1977-05-06

Similar Documents

Publication Publication Date Title
YU40004B (en) Praocess for preparing n-substituted esters of 9,10-dihydrlysergic acid
CS194740B2 (en) Method of producing derivatives of 7 beta-amino-3-cephem-3-01-4-carboxylic acid
BG24668A3 (en) Method of preparing isobutyl ester of 2,6-dimeth l-3-methoxycarbonyl-4-(2-nitrophenyl)-1,4-dihydropyridi e-5-ca-boxylic acid
HU173394B (hu) Sposob poluchenija proizvodnykh 7-metoksi-7-skobka-geterociklichnye-acilamido-skobka zakryta-acetamido-cef-3-em-4-karbonovykh kislot
EG12885A (en) Process for preparing of 2-isopropyl-4-phenyl 3-butenoic acid benzyl esters used as pesticides
YU251676A (en) Process for obtaining esters of clavulinic acid
YU189982A (en) Process for obtaining derivatives of thiophsphoric acid
PH12580A (en) An improved process for the preparation of 6-amino-penicillanic acid
CS189009B2 (en) Process for preparing esters of xanthen-9-carboxylic acid
GB1533284A (en) Process for the preparation of perpropionic acid solution
JPS51133231A (en) Process for manufacturing nnalkyll or nnalkenyllcarbamic acid ester
CS189766B2 (en) Method of preparing perpropionic acid
HU172484B (hu) Sposob poluchenija 2-alkoksikarbonilamino-5/6/-fenil-sul'foniloksi-benzimidazolov s antgel'minticheskoj aktivnost'ju
JPS5278235A (en) Process for manufacture of 4*4**bistriazinylaminoo stilbenee2*22disulfonic acid derivatives
CY1148A (en) Process for the manufacture of dithiocarbamic acid ester compounds
CS183845B2 (en) Mode of manufacture of new o-ethyl-o-/1,6-dihydro-1-chlorinemethyl-6-oxo-3-pyridazinyl/of ester of thionobenzenphosphon acid
CH612974A5 (en) Process for the preparation of 6 beta -aminomethyleneaminopenicillanic acid derivatives
YU69476A (en) Process for obtaining deoxi clavulanic acid
JPS5365843A (en) Process for preparing ester of alkyllsubstituted betaaresorcilic acid
JPS5225764A (en) Production of 33*55aryll 22furyl**33hydroxypropionic acid compound
CS189753B2 (en) Method of producing derivatives of prostanic acid
BG27357A3 (en) Method of obtaining of derivatives of 1,2- diphinil- cyclohex 1- carbonic acid
CS193073B2 (en) Process for preparing derivatives of 2-oxazolylcarbamic acid
JPS5244221A (en) Derivative of leuromucic acid
CS188286B2 (en) Method of producing derivatives of 9-oxo-15-cycloalkyl-pentanorprostanic acid