BG108479A - Карбапенемови съединения - Google Patents

Карбапенемови съединения Download PDF

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Publication number
BG108479A
BG108479A BG108479A BG10847903A BG108479A BG 108479 A BG108479 A BG 108479A BG 108479 A BG108479 A BG 108479A BG 10847903 A BG10847903 A BG 10847903A BG 108479 A BG108479 A BG 108479A
Authority
BG
Bulgaria
Prior art keywords
ylthio
hydroxyethyl
carboxylate
methylcarbapen
compound
Prior art date
Application number
BG108479A
Other languages
Bulgarian (bg)
English (en)
Inventor
Hiroshi Matsui
Original Assignee
Kyoto Pharmaceutical Industries, Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto Pharmaceutical Industries, Ltd filed Critical Kyoto Pharmaceutical Industries, Ltd
Publication of BG108479A publication Critical patent/BG108479A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG108479A 2001-05-21 2003-12-19 Карбапенемови съединения BG108479A (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2001150874 2001-05-21

Publications (1)

Publication Number Publication Date
BG108479A true BG108479A (bg) 2005-03-31

Family

ID=18995823

Family Applications (1)

Application Number Title Priority Date Filing Date
BG108479A BG108479A (bg) 2001-05-21 2003-12-19 Карбапенемови съединения

Country Status (18)

Country Link
US (1) US20040176350A1 (ja)
EP (1) EP1398314A4 (ja)
JP (1) JPWO2002094829A1 (ja)
KR (1) KR20040000466A (ja)
CN (1) CN1511156A (ja)
BG (1) BG108479A (ja)
BR (1) BR0209970A (ja)
CA (1) CA2448670A1 (ja)
CZ (1) CZ296825B6 (ja)
HU (1) HUP0400444A3 (ja)
MX (1) MXPA03010607A (ja)
NO (1) NO20035153D0 (ja)
NZ (1) NZ530170A (ja)
PL (1) PL366943A1 (ja)
RU (1) RU2289582C2 (ja)
SK (1) SK15822003A3 (ja)
WO (1) WO2002094829A1 (ja)
YU (1) YU92003A (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
CN100582106C (zh) * 2006-01-27 2010-01-20 上海医药工业研究院 一种吡咯烷硫基碳青霉烯衍生物的制备方法及其中间体
CN101357918B (zh) * 2007-06-22 2011-05-18 山东轩竹医药科技有限公司 含有异硫脲基巯基吡咯烷的培南衍生物
CN101367811B (zh) * 2007-06-28 2010-11-17 山东轩竹医药科技有限公司 碳代青霉烯类抗生素
CN101367806B (zh) * 2007-06-28 2010-11-17 山东轩竹医药科技有限公司 甲酰苯胺取代的巯基吡咯烷碳青霉烯类化合物
RU2490270C2 (ru) * 2009-03-13 2013-08-20 Даевунг Фармасьютикал Ко., Лтд. Улучшенный способ получения меропенема с применением цинкового порошка
JP2016517435A (ja) 2013-03-15 2016-06-16 カラ ファーマシューティカルズ インコーポレイテッド メロペネム誘導体及びその使用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
FI81576C (fi) * 1984-12-25 1990-11-12 Sankyo Co Foerfarande foer framstaellning av derivat av 6-(1-hydroxietyl)-2-(1,2-disubstituerade-4-pyrrolidinyltio)-2- karbapenem-3-karboxylsyra, vilka aer anvaendbara som laekemedel.
IE60588B1 (en) * 1986-07-30 1994-07-27 Sumitomo Pharma Carbapenem compound in crystalline form, and its production and use
US5242914A (en) * 1988-04-01 1993-09-07 Sankyo Company, Limited 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics
ATE114654T1 (de) * 1988-04-01 1994-12-15 Sankyo Co 2-(heterocyclylthio)carbapenemderivate, deren herstellung und deren verwendung als antibiotika.
US5712267A (en) * 1991-06-04 1998-01-27 Sankyo Company,. Limited Carbapenem derivatives, their preparation and their use as antibiotics
US5360798A (en) * 1991-07-04 1994-11-01 Shionogi Seiyaku Kabushiki Kaisha Aminooxypyrrolidinylthiocarbapenem compounds
CA2241092C (en) * 1995-12-21 2004-04-27 Sankyo Company, Limited 1-methylcarbapenem derivatives
BR9807187A (pt) * 1997-02-07 2000-01-25 Kyoto Pharma Ind Composto de carbapenem, seu uso e composto intermediário para o mesmo
DE69932927D1 (de) * 1998-05-01 2006-10-05 Kyoto Pharma Ind Cabapenemderivate, ihre anwendung und ihre zwischenprodukte
JP2000344774A (ja) * 1999-06-03 2000-12-12 Meiji Seika Kaisha Ltd カルバペネム類の製造法

Also Published As

Publication number Publication date
RU2289582C2 (ru) 2006-12-20
NO20035153L (no) 2003-11-20
SK15822003A3 (sk) 2004-06-08
CZ296825B6 (cs) 2006-06-14
WO2002094829A1 (fr) 2002-11-28
PL366943A1 (en) 2005-02-07
KR20040000466A (ko) 2004-01-03
BR0209970A (pt) 2004-04-06
EP1398314A4 (en) 2004-10-20
MXPA03010607A (es) 2004-04-02
NZ530170A (en) 2005-09-30
RU2003136767A (ru) 2005-05-10
CA2448670A1 (en) 2002-11-28
CN1511156A (zh) 2004-07-07
US20040176350A1 (en) 2004-09-09
HUP0400444A2 (hu) 2004-09-28
HUP0400444A3 (en) 2007-02-28
EP1398314A1 (en) 2004-03-17
CZ20033507A3 (en) 2004-05-12
JPWO2002094829A1 (ja) 2004-09-09
NO20035153D0 (no) 2003-11-20
YU92003A (sh) 2006-05-25

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