MXPA03010607A - Compuesto de carbapenem. - Google Patents

Compuesto de carbapenem.

Info

Publication number
MXPA03010607A
MXPA03010607A MXPA03010607A MXPA03010607A MXPA03010607A MX PA03010607 A MXPA03010607 A MX PA03010607A MX PA03010607 A MXPA03010607 A MX PA03010607A MX PA03010607 A MXPA03010607 A MX PA03010607A MX PA03010607 A MXPA03010607 A MX PA03010607A
Authority
MX
Mexico
Prior art keywords
carbapenem compound
compound
carbapenem
microbism
remedy
Prior art date
Application number
MXPA03010607A
Other languages
English (en)
Inventor
Matsui Hiroshi
Original Assignee
Kyoto Pharma Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto Pharma Ind filed Critical Kyoto Pharma Ind
Publication of MXPA03010607A publication Critical patent/MXPA03010607A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Un compuesto de carbapenem representado por la formula (i¦): (i¦) (donde los simbolos tienen los mismos significados que se definieron en la descripcion); y un antibacteriano que contiene el compuesto como el ingrediente activo. El compuesto de carbapenem tiene excelente capacidad de absorcion a traves del tracto digestivo despues de la administracion oral. Este es extremadamente util en la prevencion y remedio de enfermedades infecciosas (especialmente microbianas). (ver formula).
MXPA03010607A 2001-05-21 2002-05-17 Compuesto de carbapenem. MXPA03010607A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001150874 2001-05-21
PCT/JP2002/004767 WO2002094829A1 (fr) 2001-05-21 2002-05-17 Compose de carbapenem

Publications (1)

Publication Number Publication Date
MXPA03010607A true MXPA03010607A (es) 2004-04-02

Family

ID=18995823

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03010607A MXPA03010607A (es) 2001-05-21 2002-05-17 Compuesto de carbapenem.

Country Status (18)

Country Link
US (1) US20040176350A1 (es)
EP (1) EP1398314A4 (es)
JP (1) JPWO2002094829A1 (es)
KR (1) KR20040000466A (es)
CN (1) CN1511156A (es)
BG (1) BG108479A (es)
BR (1) BR0209970A (es)
CA (1) CA2448670A1 (es)
CZ (1) CZ296825B6 (es)
HU (1) HUP0400444A3 (es)
MX (1) MXPA03010607A (es)
NO (1) NO20035153D0 (es)
NZ (1) NZ530170A (es)
PL (1) PL366943A1 (es)
RU (1) RU2289582C2 (es)
SK (1) SK15822003A3 (es)
WO (1) WO2002094829A1 (es)
YU (1) YU92003A (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
CN100582106C (zh) * 2006-01-27 2010-01-20 上海医药工业研究院 一种吡咯烷硫基碳青霉烯衍生物的制备方法及其中间体
CN101357918B (zh) * 2007-06-22 2011-05-18 山东轩竹医药科技有限公司 含有异硫脲基巯基吡咯烷的培南衍生物
CN101367806B (zh) * 2007-06-28 2010-11-17 山东轩竹医药科技有限公司 甲酰苯胺取代的巯基吡咯烷碳青霉烯类化合物
CN101367811B (zh) * 2007-06-28 2010-11-17 山东轩竹医药科技有限公司 碳代青霉烯类抗生素
WO2010104336A2 (ko) * 2009-03-13 2010-09-16 주식회사 대웅제약 아연 분말을 이용한 메로페넴의 개선된 제조방법
AU2014227737B2 (en) * 2013-03-15 2018-05-17 KALA BIO, Inc. Meropenem derivatives and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
JPS61275279A (ja) * 1984-12-25 1986-12-05 Sankyo Co Ltd カルバペネム化合物
IE60588B1 (en) * 1986-07-30 1994-07-27 Sumitomo Pharma Carbapenem compound in crystalline form, and its production and use
US5242914A (en) * 1988-04-01 1993-09-07 Sankyo Company, Limited 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics
ES2067534T3 (es) * 1988-04-01 1995-04-01 Sankyo Co Derivados de 2-(heterocicliltio)carbapenemo, su preparacion y su aplicacion como antibioticos.
US5712267A (en) * 1991-06-04 1998-01-27 Sankyo Company,. Limited Carbapenem derivatives, their preparation and their use as antibiotics
US5360798A (en) * 1991-07-04 1994-11-01 Shionogi Seiyaku Kabushiki Kaisha Aminooxypyrrolidinylthiocarbapenem compounds
KR100386993B1 (ko) * 1995-12-21 2003-12-18 상꾜 가부시키가이샤 1-메틸카르바페넴유도체
RU2178792C2 (ru) * 1997-02-07 2002-01-27 Киото Фармасьютикал Индастриз, Лтд. Производные карбапенема, антибактериальное средство на его основе и его промежуточное соединение
ID27081A (id) * 1998-05-01 2001-02-22 Kyoto Pharma Ind Senyawa-senyawa turunan karbapenem, penggunaan serta senyawa-senyawa intermedietnya
JP2000344774A (ja) * 1999-06-03 2000-12-12 Meiji Seika Kaisha Ltd カルバペネム類の製造法

Also Published As

Publication number Publication date
YU92003A (sh) 2006-05-25
EP1398314A1 (en) 2004-03-17
CN1511156A (zh) 2004-07-07
SK15822003A3 (sk) 2004-06-08
WO2002094829A1 (fr) 2002-11-28
CA2448670A1 (en) 2002-11-28
RU2003136767A (ru) 2005-05-10
CZ296825B6 (cs) 2006-06-14
BR0209970A (pt) 2004-04-06
US20040176350A1 (en) 2004-09-09
NO20035153L (no) 2003-11-20
PL366943A1 (en) 2005-02-07
KR20040000466A (ko) 2004-01-03
HUP0400444A3 (en) 2007-02-28
NZ530170A (en) 2005-09-30
NO20035153D0 (no) 2003-11-20
RU2289582C2 (ru) 2006-12-20
CZ20033507A3 (en) 2004-05-12
BG108479A (bg) 2005-03-31
JPWO2002094829A1 (ja) 2004-09-09
EP1398314A4 (en) 2004-10-20
HUP0400444A2 (hu) 2004-09-28

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