BR0209970A - Composto de carbapenem - Google Patents

Composto de carbapenem

Info

Publication number
BR0209970A
BR0209970A BR0209970-5A BR0209970A BR0209970A BR 0209970 A BR0209970 A BR 0209970A BR 0209970 A BR0209970 A BR 0209970A BR 0209970 A BR0209970 A BR 0209970A
Authority
BR
Brazil
Prior art keywords
carbapenem compound
compound
infectious diseases
present
carbapenem
Prior art date
Application number
BR0209970-5A
Other languages
English (en)
Inventor
Hiroshi Matsui
Original Assignee
Kyoto Pharma Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto Pharma Ind filed Critical Kyoto Pharma Ind
Publication of BR0209970A publication Critical patent/BR0209970A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

"COMPOSTO DE CARBAPENEM". A presente invenção refere-se a um composto de carbapenem representado pela fórmula (I<39>): em que cada símbolo é como definido no relatório descritivo, e um agente antibacteriano contendo este composto como um ingrediente ativo são proporcionados. O composto de carbapenem da presente invenção é superior em capacidade de absorção a partir do trato gastro-intestinal, por administração oral, e extremamente útil para a profilaxia ou tratamento de doenças infecciosas (particularmente, doenças infecciosas bacterianas).
BR0209970-5A 2001-05-21 2002-05-17 Composto de carbapenem BR0209970A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001150874 2001-05-21
PCT/JP2002/004767 WO2002094829A1 (fr) 2001-05-21 2002-05-17 Compose de carbapenem

Publications (1)

Publication Number Publication Date
BR0209970A true BR0209970A (pt) 2004-04-06

Family

ID=18995823

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209970-5A BR0209970A (pt) 2001-05-21 2002-05-17 Composto de carbapenem

Country Status (18)

Country Link
US (1) US20040176350A1 (pt)
EP (1) EP1398314A4 (pt)
JP (1) JPWO2002094829A1 (pt)
KR (1) KR20040000466A (pt)
CN (1) CN1511156A (pt)
BG (1) BG108479A (pt)
BR (1) BR0209970A (pt)
CA (1) CA2448670A1 (pt)
CZ (1) CZ296825B6 (pt)
HU (1) HUP0400444A3 (pt)
MX (1) MXPA03010607A (pt)
NO (1) NO20035153D0 (pt)
NZ (1) NZ530170A (pt)
PL (1) PL366943A1 (pt)
RU (1) RU2289582C2 (pt)
SK (1) SK15822003A3 (pt)
WO (1) WO2002094829A1 (pt)
YU (1) YU92003A (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
CN100582106C (zh) * 2006-01-27 2010-01-20 上海医药工业研究院 一种吡咯烷硫基碳青霉烯衍生物的制备方法及其中间体
CN101357918B (zh) * 2007-06-22 2011-05-18 山东轩竹医药科技有限公司 含有异硫脲基巯基吡咯烷的培南衍生物
CN101367806B (zh) * 2007-06-28 2010-11-17 山东轩竹医药科技有限公司 甲酰苯胺取代的巯基吡咯烷碳青霉烯类化合物
CN101367811B (zh) * 2007-06-28 2010-11-17 山东轩竹医药科技有限公司 碳代青霉烯类抗生素
EP2407468B1 (en) * 2009-03-13 2014-04-16 Daewoong Pharmaceutical Co., Ltd. Improved method for preparing meropenem using zinc powder
BR112015023621A8 (pt) 2013-03-15 2018-01-23 Kala Pharmaceuticals Inc derivados de meropenem e suas utilizações

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
JPS61275279A (ja) * 1984-12-25 1986-12-05 Sankyo Co Ltd カルバペネム化合物
IE60588B1 (en) * 1986-07-30 1994-07-27 Sumitomo Pharma Carbapenem compound in crystalline form, and its production and use
EP0597821A1 (en) * 1988-04-01 1994-05-18 Sankyo Company Limited 2-(Heterocyclylthio)carbapenem derivatives their preparation and their use as antibiotics
US5242914A (en) * 1988-04-01 1993-09-07 Sankyo Company, Limited 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics
US5712267A (en) * 1991-06-04 1998-01-27 Sankyo Company,. Limited Carbapenem derivatives, their preparation and their use as antibiotics
US5360798A (en) * 1991-07-04 1994-11-01 Shionogi Seiyaku Kabushiki Kaisha Aminooxypyrrolidinylthiocarbapenem compounds
ATE223411T1 (de) * 1995-12-21 2002-09-15 Sankyo Co 1-methylcarbapenem-derivate
SK108099A3 (en) * 1997-02-07 2000-03-13 Kyoto Pharmaceutical Ind Carbapenem compounds, use thereof, and intermediate compounds of the same
BR9910098A (pt) * 1998-05-01 2000-12-26 Kyoto Pharma Ind Derivados de carbapenem, utilização dos mesmos e compostos intermediários dos mesmos
JP2000344774A (ja) * 1999-06-03 2000-12-12 Meiji Seika Kaisha Ltd カルバペネム類の製造法

Also Published As

Publication number Publication date
NO20035153L (no) 2003-11-20
BG108479A (bg) 2005-03-31
EP1398314A1 (en) 2004-03-17
EP1398314A4 (en) 2004-10-20
SK15822003A3 (sk) 2004-06-08
RU2289582C2 (ru) 2006-12-20
US20040176350A1 (en) 2004-09-09
MXPA03010607A (es) 2004-04-02
NZ530170A (en) 2005-09-30
WO2002094829A1 (fr) 2002-11-28
JPWO2002094829A1 (ja) 2004-09-09
CZ296825B6 (cs) 2006-06-14
KR20040000466A (ko) 2004-01-03
CN1511156A (zh) 2004-07-07
HUP0400444A3 (en) 2007-02-28
HUP0400444A2 (hu) 2004-09-28
PL366943A1 (en) 2005-02-07
CZ20033507A3 (en) 2004-05-12
NO20035153D0 (no) 2003-11-20
YU92003A (sh) 2006-05-25
CA2448670A1 (en) 2002-11-28
RU2003136767A (ru) 2005-05-10

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 6A., 7A., E 8A. ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2060 DE 29/06/2010.