YU92003A - Karbapenem jedinjenje - Google Patents

Karbapenem jedinjenje

Info

Publication number
YU92003A
YU92003A YU92003A YUP92003A YU92003A YU 92003 A YU92003 A YU 92003A YU 92003 A YU92003 A YU 92003A YU P92003 A YUP92003 A YU P92003A YU 92003 A YU92003 A YU 92003A
Authority
YU
Yugoslavia
Prior art keywords
carbapenem compound
compound
carbapenem
microbism
remedy
Prior art date
Application number
YU92003A
Other languages
English (en)
Inventor
Hiroshi Matsui
Original Assignee
Kyoto Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto Pharmaceutical Industries Ltd. filed Critical Kyoto Pharmaceutical Industries Ltd.
Publication of YU92003A publication Critical patent/YU92003A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Dobijanje karbapenem jedinjenja predstavljenog formulom (I'): gde je svaki od simbola opisan u specifikaciji i antibakterijskog agensa koji sadrži ovo jedinjenje kao aktivan sastojak. Karbapenem jedinjenje iz ovog pronalaska je superiorno u apsorptivnosti iz gastrointestinalnog trakta nakon oralne primene i veoma je korisno u profilaksi i lečenju infektivnih bolesti (posebno, bakterijskih infektivnih bolesti).[A carbapenem compound represented by the formula (I'): (I') (wherein the symbols have the same meanings as defined in the description); and an antibacterial containing the compound as the active ingredient. The carbapenem compound has excellent absorbability through the digestive tract after oral administration. It is extremely useful in the prevention of and remedy for infectious diseases (especially microbism).
YU92003A 2001-05-21 2002-05-17 Karbapenem jedinjenje YU92003A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2001150874 2001-05-21

Publications (1)

Publication Number Publication Date
YU92003A true YU92003A (sh) 2006-05-25

Family

ID=18995823

Family Applications (1)

Application Number Title Priority Date Filing Date
YU92003A YU92003A (sh) 2001-05-21 2002-05-17 Karbapenem jedinjenje

Country Status (18)

Country Link
US (1) US20040176350A1 (sh)
EP (1) EP1398314A4 (sh)
JP (1) JPWO2002094829A1 (sh)
KR (1) KR20040000466A (sh)
CN (1) CN1511156A (sh)
BG (1) BG108479A (sh)
BR (1) BR0209970A (sh)
CA (1) CA2448670A1 (sh)
CZ (1) CZ296825B6 (sh)
HU (1) HUP0400444A3 (sh)
MX (1) MXPA03010607A (sh)
NO (1) NO20035153D0 (sh)
NZ (1) NZ530170A (sh)
PL (1) PL366943A1 (sh)
RU (1) RU2289582C2 (sh)
SK (1) SK15822003A3 (sh)
WO (1) WO2002094829A1 (sh)
YU (1) YU92003A (sh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
CN100582106C (zh) * 2006-01-27 2010-01-20 上海医药工业研究院 一种吡咯烷硫基碳青霉烯衍生物的制备方法及其中间体
CN101357918B (zh) * 2007-06-22 2011-05-18 山东轩竹医药科技有限公司 含有异硫脲基巯基吡咯烷的培南衍生物
CN101367811B (zh) * 2007-06-28 2010-11-17 山东轩竹医药科技有限公司 碳代青霉烯类抗生素
CN101367806B (zh) * 2007-06-28 2010-11-17 山东轩竹医药科技有限公司 甲酰苯胺取代的巯基吡咯烷碳青霉烯类化合物
BRPI1009816A2 (pt) * 2009-03-13 2015-08-25 Dae Woong Pharma "método para preparar um composto."
AU2014227737B2 (en) 2013-03-15 2018-05-17 KALA BIO, Inc. Meropenem derivatives and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
JPS61275279A (ja) * 1984-12-25 1986-12-05 Sankyo Co Ltd カルバペネム化合物
IE60588B1 (en) * 1986-07-30 1994-07-27 Sumitomo Pharma Carbapenem compound in crystalline form, and its production and use
IE66711B1 (en) * 1988-04-01 1996-01-24 Sankyo Co 2-(heterocyclylthio) carbapenem derivatives their preparation and their use as antibiotics
US5242914A (en) * 1988-04-01 1993-09-07 Sankyo Company, Limited 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics
US5712267A (en) * 1991-06-04 1998-01-27 Sankyo Company,. Limited Carbapenem derivatives, their preparation and their use as antibiotics
US5360798A (en) * 1991-07-04 1994-11-01 Shionogi Seiyaku Kabushiki Kaisha Aminooxypyrrolidinylthiocarbapenem compounds
KR100386993B1 (ko) * 1995-12-21 2003-12-18 상꾜 가부시키가이샤 1-메틸카르바페넴유도체
NZ337532A (en) * 1997-02-07 2001-06-29 Kyoto Pharma Ind Carbapenem derivatives useful as an antibiotic
KR100589030B1 (ko) * 1998-05-01 2006-06-13 교토 야쿠힝 고교 가부시키가이샤 카르바페넴 유도체, 그 사용 방법 및 그 중간체 화합물
JP2000344774A (ja) * 1999-06-03 2000-12-12 Meiji Seika Kaisha Ltd カルバペネム類の製造法

Also Published As

Publication number Publication date
EP1398314A1 (en) 2004-03-17
WO2002094829A1 (fr) 2002-11-28
EP1398314A4 (en) 2004-10-20
RU2289582C2 (ru) 2006-12-20
HUP0400444A2 (hu) 2004-09-28
PL366943A1 (en) 2005-02-07
NZ530170A (en) 2005-09-30
BG108479A (bg) 2005-03-31
NO20035153L (no) 2003-11-20
CN1511156A (zh) 2004-07-07
CA2448670A1 (en) 2002-11-28
RU2003136767A (ru) 2005-05-10
KR20040000466A (ko) 2004-01-03
MXPA03010607A (es) 2004-04-02
JPWO2002094829A1 (ja) 2004-09-09
CZ296825B6 (cs) 2006-06-14
HUP0400444A3 (en) 2007-02-28
US20040176350A1 (en) 2004-09-09
CZ20033507A3 (en) 2004-05-12
BR0209970A (pt) 2004-04-06
SK15822003A3 (sk) 2004-06-08
NO20035153D0 (no) 2003-11-20

Similar Documents

Publication Publication Date Title
UA84266C2 (uk) Дозована лікарська форма у вигляді таблетки або пелети для перорального введення, яка містить інгібітор pde 4 та полівінілпіролідон, способи її одержання та застосування
YU29502A (sh) Proces dobijanja 4"-supstituisanog 9-dezokso-9a-aza-9a derivata homoeritromicina a
AUPR213700A0 (en) Antiviral agents
IL205420A0 (en) Immunoregulatory compounds and derivatives
EP1443928A4 (en) TREATMENT OF NEURODEGENERATIVE DISEASES AND CANCER IN THE BRAIN
WO2004026306A3 (en) Pyrazole derivatives as transforming growth factor (tgf) inhibitors
CA2430967A1 (en) Remedies for bone marrow suppression and infectious diseases and white blood cell count elevating agents
IL136062A0 (en) Oxazolidinone derivatives and pharmaceutical compositions
BG108498A (en) New derivatives of oxazolidinones as antibacterial agents
GB0109122D0 (en) Novel compounds
DE60012988D1 (en) Taxane mit carbonaten in c-4
HK1045464A1 (en) Use of sulfodehydroabietic acid for the treatment of inflammatory bowel disease
MXPA03010607A (es) Compuesto de carbapenem.
SG162614A1 (en) Bicyclic 6-alkylidene-penems as beta-lactamases inhibitors
CA2104531A1 (en) Antimicrobial Agent
YU66700A (sh) Derivati karbapenema, njihovo korišćenje i intermedijarna jedinjenja istih
CA2386685A1 (en) Use of pleuromutilin derivatives for transdermal treatment of bacterial diseases
AU5390900A (en) Potassium channel blocking agents
DE602005017629D1 (de) Pharmazeutische zusammensetzungen zur behandlung von leishmaniasis
CA2248794A1 (en) Medicament for preventive and treatment for viral infectious diseases
AU2001244999A1 (en) Naphthamide neurokinin antagonists for use as medicaments
MXPA04003738A (es) Composiciones farmaceuticas que contienen macrolidos.
EP2266558A3 (en) Treatment of neuropathic pain with N-methyl-D-aspartate (NMDA) receptor antagonists
HK1083839A1 (en) Indoline compound and medicinal use thereof
CA2409845A1 (en) Active substance combination containing a compound with an opioid effect and at least one further compound of formula i