BE903693A - Derives de flavolignanes, procedes pour leur preparation et medicaments contenant ces composes. - Google Patents
Derives de flavolignanes, procedes pour leur preparation et medicaments contenant ces composes.Info
- Publication number
- BE903693A BE903693A BE2/60850A BE2060850A BE903693A BE 903693 A BE903693 A BE 903693A BE 2/60850 A BE2/60850 A BE 2/60850A BE 2060850 A BE2060850 A BE 2060850A BE 903693 A BE903693 A BE 903693A
- Authority
- BE
- Belgium
- Prior art keywords
- flavolignan
- derivatives
- compounds
- processes
- preparation
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 101100490437 Mus musculus Acvrl1 gene Proteins 0.000 abstract 1
- 206010028520 Mycotoxicosis Diseases 0.000 abstract 1
- 231100000006 Mycotoxicosis Toxicity 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 208000019425 cirrhosis of liver Diseases 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- SEBFKMXJBCUCAI-HKTJVKLFSA-N silibinin Chemical class C1=C(O)C(OC)=CC([C@@H]2[C@H](OC3=CC=C(C=C3O2)[C@@H]2[C@H](C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 SEBFKMXJBCUCAI-HKTJVKLFSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Silicon Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843442639 DE3442639A1 (de) | 1984-11-22 | 1984-11-22 | Flavolignanderivate, verfahren zu deren herstellung und arzneimittel, die diese verbindungen enthalten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE903693A true BE903693A (fr) | 1986-05-22 |
Family
ID=6250903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE2/60850A BE903693A (fr) | 1984-11-22 | 1985-11-22 | Derives de flavolignanes, procedes pour leur preparation et medicaments contenant ces composes. |
Country Status (29)
| Country | Link |
|---|---|
| JP (1) | JPS61143377A (enExample) |
| KR (1) | KR870001020B1 (enExample) |
| AR (1) | AR240931A1 (enExample) |
| AT (1) | AT393268B (enExample) |
| BE (1) | BE903693A (enExample) |
| CA (1) | CA1337124C (enExample) |
| CH (1) | CH659473A5 (enExample) |
| CS (1) | CS273610B2 (enExample) |
| DD (1) | DD259191A1 (enExample) |
| DE (1) | DE3442639A1 (enExample) |
| DK (1) | DK164865C (enExample) |
| EG (1) | EG19424A (enExample) |
| ES (1) | ES8609311A1 (enExample) |
| FI (1) | FI84064C (enExample) |
| FR (1) | FR2573427B1 (enExample) |
| GB (1) | GB2167414B (enExample) |
| HU (1) | HU195503B (enExample) |
| IE (1) | IE58791B1 (enExample) |
| IT (1) | IT1190426B (enExample) |
| LU (1) | LU86163A1 (enExample) |
| MX (1) | MX168415B (enExample) |
| NL (1) | NL192387C (enExample) |
| NO (1) | NO160205C (enExample) |
| PL (1) | PL146890B1 (enExample) |
| PT (1) | PT81532B (enExample) |
| SE (1) | SE465676B (enExample) |
| SU (1) | SU1436875A3 (enExample) |
| YU (1) | YU43689B (enExample) |
| ZA (1) | ZA858951B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8716918D0 (en) * | 1987-07-17 | 1987-08-26 | Inverni Della Beffa Spa | Soluble derivatives of silybin |
| US5262439A (en) * | 1992-04-30 | 1993-11-16 | The Regents Of The University Of California | Soluble analogs of probucol |
| NZ560633A (en) * | 2005-03-11 | 2011-08-26 | Neuprotect Pty Ltd | Flavonoid compounds and uses thereof |
| RU2482844C2 (ru) * | 2007-11-15 | 2013-05-27 | Мадаус Гмбх | Силибининовый компонент для лечения гепатита |
| US20110182858A1 (en) | 2007-11-15 | 2011-07-28 | Madaus Gmbh | Silibinin component for the treatment of hepatitis |
| EP2430017B1 (en) | 2009-05-14 | 2016-06-29 | Madaus GmbH | A method for preparing AMORPHOUS SILIBININ |
| PL2849736T3 (pl) | 2012-07-05 | 2019-06-28 | Nutramax Laboratories, Inc. | Kompozycje zawierające prekursor sulforafanu glukorafaninę, glukozydazę, kwas askorbinowy i ekstrakt lub proszek z ostropestu plamistego |
| CN103113359B (zh) * | 2013-02-22 | 2016-01-06 | 西安安健药业有限公司 | 水飞蓟宾二偏琥珀酸酯及其药用盐 |
| CN103193768B (zh) * | 2013-02-22 | 2016-03-30 | 西安安健药业有限公司 | 治疗肝病的水飞蓟宾二偏琥珀酸酯异构体 |
| CN103172622B (zh) * | 2013-02-22 | 2015-11-04 | 西安安健药业有限公司 | 水飞蓟宾二偏琥珀酸酯的活性异构体 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1963318A1 (de) * | 1969-12-17 | 1971-06-24 | Schwabe Willmar Gmbh & Co | Silybinhalbester der Bernsteinsaeure und der Phthalsaeure,ihre Salze mit pharmakologisch vertraglichen Basen,Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Arzneipraeparaten |
-
1984
- 1984-11-22 DE DE19843442639 patent/DE3442639A1/de active Granted
-
1985
- 1985-11-11 IE IE280885A patent/IE58791B1/en not_active IP Right Cessation
- 1985-11-13 LU LU86163A patent/LU86163A1/de unknown
- 1985-11-14 AR AR302267A patent/AR240931A1/es active
- 1985-11-14 YU YU1786/85A patent/YU43689B/xx unknown
- 1985-11-15 GB GB08528226A patent/GB2167414B/en not_active Expired
- 1985-11-18 FI FI854535A patent/FI84064C/fi not_active IP Right Cessation
- 1985-11-18 NL NL8503171A patent/NL192387C/nl not_active IP Right Cessation
- 1985-11-19 AT AT3371/85A patent/AT393268B/de not_active IP Right Cessation
- 1985-11-19 CH CH4935/85A patent/CH659473A5/de not_active IP Right Cessation
- 1985-11-20 CS CS837885A patent/CS273610B2/cs unknown
- 1985-11-20 DD DD85283042A patent/DD259191A1/de not_active IP Right Cessation
- 1985-11-20 CA CA000495804A patent/CA1337124C/en not_active Expired - Fee Related
- 1985-11-20 SE SE8505487A patent/SE465676B/sv not_active IP Right Cessation
- 1985-11-21 ES ES549116A patent/ES8609311A1/es not_active Expired
- 1985-11-21 SU SU853985401A patent/SU1436875A3/ru active
- 1985-11-21 HU HU854448A patent/HU195503B/hu not_active IP Right Cessation
- 1985-11-21 DK DK537785A patent/DK164865C/da not_active IP Right Cessation
- 1985-11-21 IT IT22932/85A patent/IT1190426B/it active
- 1985-11-21 EG EG74085A patent/EG19424A/xx active
- 1985-11-21 PL PL1985256374A patent/PL146890B1/pl unknown
- 1985-11-21 PT PT81532A patent/PT81532B/pt not_active IP Right Cessation
- 1985-11-21 NO NO854655A patent/NO160205C/no not_active IP Right Cessation
- 1985-11-21 ZA ZA858951A patent/ZA858951B/xx unknown
- 1985-11-22 FR FR858517321A patent/FR2573427B1/fr not_active Expired
- 1985-11-22 MX MX009022A patent/MX168415B/es unknown
- 1985-11-22 BE BE2/60850A patent/BE903693A/fr not_active IP Right Cessation
- 1985-11-22 JP JP60261629A patent/JPS61143377A/ja active Granted
- 1985-11-22 KR KR1019850008733A patent/KR870001020B1/ko not_active Expired
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: DR. MADAUS G.M.B.H. & CO. Effective date: 20011130 |