BE826440A - Nouveaux 2-tetrahydrofurfuryl-6,7-benzomorphanes, leurs sels d'addition avec des acides, leurs utilisation comme medicament et leur procede de fabrication - Google Patents

Nouveaux 2-tetrahydrofurfuryl-6,7-benzomorphanes, leurs sels d'addition avec des acides, leurs utilisation comme medicament et leur procede de fabrication

Info

Publication number
BE826440A
BE826440A BE154138A BE154138A BE826440A BE 826440 A BE826440 A BE 826440A BE 154138 A BE154138 A BE 154138A BE 154138 A BE154138 A BE 154138A BE 826440 A BE826440 A BE 826440A
Authority
BE
Belgium
Prior art keywords
benzomorphanes
tetrahydrofurfuryl
acids
manufacturing
new
Prior art date
Application number
BE154138A
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE826440A publication Critical patent/BE826440A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BE154138A 1974-03-09 1975-03-07 Nouveaux 2-tetrahydrofurfuryl-6,7-benzomorphanes, leurs sels d'addition avec des acides, leurs utilisation comme medicament et leur procede de fabrication BE826440A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
BE826440A true BE826440A (fr) 1975-09-08

Family

ID=5909593

Family Applications (1)

Application Number Title Priority Date Filing Date
BE154138A BE826440A (fr) 1974-03-09 1975-03-07 Nouveaux 2-tetrahydrofurfuryl-6,7-benzomorphanes, leurs sels d'addition avec des acides, leurs utilisation comme medicament et leur procede de fabrication

Country Status (25)

Country Link
JP (1) JPS5827275B2 (zh)
AT (1) AT344332B (zh)
BE (1) BE826440A (zh)
BG (3) BG25087A3 (zh)
CA (1) CA1049511A (zh)
CH (8) CH612425A5 (zh)
CS (1) CS188221B2 (zh)
DD (1) DD119236A5 (zh)
DE (1) DE2411382C3 (zh)
DK (1) DK137188C (zh)
ES (6) ES440347A1 (zh)
FI (1) FI63571C (zh)
FR (1) FR2262984B1 (zh)
GB (1) GB1496418A (zh)
HU (1) HU177408B (zh)
IE (1) IE40945B1 (zh)
IL (1) IL46760A (zh)
NL (1) NL7502724A (zh)
NO (1) NO141800C (zh)
PH (1) PH14127A (zh)
PL (3) PL93499B1 (zh)
RO (2) RO69617A (zh)
SE (1) SE421919B (zh)
SU (3) SU577982A3 (zh)
ZA (1) ZA751394B (zh)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
WO1996028412A1 (en) * 1995-03-10 1996-09-19 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
JP5451611B2 (ja) 2007-07-26 2014-03-26 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１のサイクリックインヒビター
JP5769970B2 (ja) 2007-11-16 2015-08-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンゾモルファン及び関連骨格のアリール−及びヘテロアリールカルボニル誘導体、かかる化合物を含有する医薬及びこれらの使用
JP5490014B2 (ja) 2007-12-11 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の環状尿素阻害剤
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
WO2009094169A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2254872A2 (en) 2008-02-15 2010-12-01 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
JP5301563B2 (ja) 2008-05-01 2013-09-25 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
EP2291370B1 (en) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8569292B2 (en) 2008-05-01 2013-10-29 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
TW200950780A (en) 2008-05-13 2009-12-16 Boehringer Ingelheim Int Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
JP5777030B2 (ja) 2008-07-25 2015-09-09 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤
JP5379160B2 (ja) 2008-07-25 2013-12-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
US8735585B2 (en) 2011-08-17 2014-05-27 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
AU7894275A (en) 1976-09-16
CH622017A5 (en) 1981-03-13
IL46760A0 (en) 1975-05-22
DK137188C (da) 1978-07-03
HU177408B (en) 1981-10-28
CH622016A5 (en) 1981-03-13
DE2411382A1 (de) 1975-09-18
ES440350A1 (es) 1977-03-16
FI63571C (fi) 1983-07-11
ATA153875A (de) 1977-11-15
CH620681A5 (en) 1980-12-15
NL7502724A (nl) 1975-09-11
DD119236A5 (zh) 1976-04-12
ES440347A1 (es) 1977-06-01
ES440349A1 (es) 1977-03-01
DK137188B (da) 1978-01-30
CH612425A5 (en) 1979-07-31
PL93699B1 (zh) 1977-06-30
NO141800B (no) 1980-02-04
PL93700B1 (zh) 1977-06-30
CH622014A5 (en) 1981-03-13
IE40945B1 (en) 1979-09-12
ES440348A1 (es) 1977-06-01
NO750773L (zh) 1975-09-10
FR2262984A1 (zh) 1975-10-03
SE7502592L (zh) 1975-09-10
SU588916A3 (ru) 1978-01-15
BG25087A3 (en) 1978-07-12
CS188221B2 (en) 1979-02-28
CH620439A5 (en) 1980-11-28
CH622015A5 (en) 1981-03-13
CH620440A5 (en) 1980-11-28
PH14127A (en) 1981-02-26
PL93499B1 (zh) 1977-05-30
RO69617A (ro) 1980-08-15
SU577983A3 (ru) 1977-10-25
NO141800C (no) 1980-06-04
RO70051A (ro) 1980-12-30
ES440345A1 (es) 1977-03-01
ES440346A1 (es) 1977-03-01
IE40945L (en) 1975-09-09
JPS50123675A (zh) 1975-09-29
FI63571B (fi) 1983-03-31
GB1496418A (en) 1977-12-30
SU577982A3 (ru) 1977-10-25
ZA751394B (en) 1976-11-24
DE2411382C3 (de) 1979-09-06
AT344332B (de) 1978-07-10
FI750652A (zh) 1975-09-10
BG24814A4 (en) 1978-05-12
JPS5827275B2 (ja) 1983-06-08
CA1049511A (en) 1979-02-27
IL46760A (en) 1978-12-17
SE421919B (sv) 1982-02-08
BG24813A4 (en) 1978-05-12
FR2262984B1 (zh) 1978-07-28
DK92975A (zh) 1975-09-10
DE2411382B2 (de) 1979-01-18

Similar Documents

Publication Publication Date Title
BE826440A (fr) Nouveaux 2-tetrahydrofurfuryl-6,7-benzomorphanes, leurs sels d'addition avec des acides, leurs utilisation comme medicament et leur procede de fabrication
BE832099R (fr) Nouveaux 2-tetrahydrofurfuryl-6,7-benzomorphanes, leurs sels d'addition avec des acides, leur utilisation comme medicament et leurs procedes de fabrication
FR2274289A1 (fr) Nouveaux derives d'acide oxy-16 prostanoique, leur procede de preparation et leur utilisation therapeutique
FR2340735A1 (fr) Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
BE781878A (fr) Nouveaux esters dissymetriques d'acides 1,4-dihydropyridine-dicarboxyliques, leur procede de preparation et leur application comme medicament
BE836924A (fr) Nouveaux azolyl - (1) - methanes et leurs sels, leur procede de preparation et medicament les contenant
FR2282895A1 (fr) Derives d'acides thio-cephem-carboxyliques utiles comme medicaments et leur procede de preparation
FR2281761A1 (fr) Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
BE834113A (fr) Production de 1,4-butane diol a partir d'acide 2-butene-1,4-dioique
BE828686A (fr) Nouvel acide penicillanique, son procede de preparation et medicament le contenant
BE818989A (fr) Amides n -(1-(omega)-phenylalcoyl-piperidyl-4)-n -(alpha -pyriyl)- carboxyliques, leurs sels d'addition d'acide, leur procede de preparation et leur application comme medicaments
BE854925A (fr) Acides 12-azaprostanoiques utiles comme medicament
BE825150A (fr) Nouveaux acides amidocarbonylthiobarbituriques et leurs sels, leur procede de preparation et leur application,comme insecticides,acaricides et fongicides
BE828430A (fr) Phenylalcoylamines, leur procede d'obtention et leur application commemedicaments
FR2353540A1 (fr) Nouveaux benzamides applicables comme medicaments
BE834051A (fr) Nouvelles 2-phenylimino-imidazolidines, disubstituees en 2 et 6, leurs sels d'addition avec des acides, medicaments a base de ces nouveaux composes et procedes de fabrication de ces medicaments
FR2338951A1 (fr) Nouveaux esters-17 a d'hydroxy-17 a-progestatifs utiles comme medicaments et leurs procedes de preparation
BE845563A (fr) N-tetrahydrofurfuryl-noroxymorphones, leurs sels d'addition avec des acides, procede pour leur preparation et medicaments en renfermant
FR2319332A1 (fr) Nouveaux derives de l'aminobenzocycloheptene et leurs sels, procede de preparation et application a titre de medicaments desdits produits
FR2346005A1 (fr) Nouvelles lactones d'acides libres du type prostaglandine, leur procede de preparation et medicament les contenant
BE832858A (fr) Esters phenyliques d'acides 2-carbalcoxyamino-benzimidazolyl-5(6)-sulfoniques, leur procede de preparation et leurs applications
FR2321294A1 (fr) Derives d'acides 7b-amino-3-cephem-3-carbonylmethyl-4-carboxyliques utiles comme medicaments
BE833807A (fr) Phenoxyalkanecarbonamides d'acides thiazolidinecarboxyliques substitues, procede pour leur preparation et application comme medicament
FR2330395A1 (fr) Ester isobutylique de l'acide 2,6-dimethyl-3-methoxycarbonyl-4-(2'nitrophenyl)-1,4-dihydropyridine-5-carboxylique, son procede de preparation et medicament a usage coronarien le contenant
BE794424A (fr) Nouveaux dibenzocycloheptenes, leur procede d'obtention et leur application comme medicament

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: C.H. BOEHRINGER SOHN

Effective date: 19890331