IL46760A - 2-tetrahydrofurfuryl-6,7-benzomorphane derivatives,their production and pharmaceutical compositions containing them - Google Patents
2-tetrahydrofurfuryl-6,7-benzomorphane derivatives,their production and pharmaceutical compositions containing themInfo
- Publication number
- IL46760A IL46760A IL46760A IL4676075A IL46760A IL 46760 A IL46760 A IL 46760A IL 46760 A IL46760 A IL 46760A IL 4676075 A IL4676075 A IL 4676075A IL 46760 A IL46760 A IL 46760A
- Authority
- IL
- Israel
- Prior art keywords
- tetrahydrofurfuryl
- production
- pharmaceutical compositions
- compositions containing
- benzomorphane derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2411382A DE2411382C3 (de) | 1974-03-09 | 1974-03-09 | 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
IL46760A0 IL46760A0 (en) | 1975-05-22 |
IL46760A true IL46760A (en) | 1978-12-17 |
Family
ID=5909593
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL46760A IL46760A (en) | 1974-03-09 | 1975-03-07 | 2-tetrahydrofurfuryl-6,7-benzomorphane derivatives,their production and pharmaceutical compositions containing them |
Country Status (25)
Country | Link |
---|---|
JP (1) | JPS5827275B2 (zh) |
AT (1) | AT344332B (zh) |
BE (1) | BE826440A (zh) |
BG (3) | BG25087A3 (zh) |
CA (1) | CA1049511A (zh) |
CH (8) | CH612425A5 (zh) |
CS (1) | CS188221B2 (zh) |
DD (1) | DD119236A5 (zh) |
DE (1) | DE2411382C3 (zh) |
DK (1) | DK137188C (zh) |
ES (6) | ES440349A1 (zh) |
FI (1) | FI63571C (zh) |
FR (1) | FR2262984B1 (zh) |
GB (1) | GB1496418A (zh) |
HU (1) | HU177408B (zh) |
IE (1) | IE40945B1 (zh) |
IL (1) | IL46760A (zh) |
NL (1) | NL7502724A (zh) |
NO (1) | NO141800C (zh) |
PH (1) | PH14127A (zh) |
PL (3) | PL93699B1 (zh) |
RO (2) | RO69617A (zh) |
SE (1) | SE421919B (zh) |
SU (3) | SU577982A3 (zh) |
ZA (1) | ZA751394B (zh) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2716687A1 (de) * | 1977-04-15 | 1978-10-19 | Boehringer Sohn Ingelheim | 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel |
DE2828039A1 (de) * | 1978-06-26 | 1980-01-10 | Boehringer Sohn Ingelheim | 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung |
ES2157424T3 (es) * | 1995-03-10 | 2001-08-16 | Photocure Asa | Esteres de acido 5-aminolevulinico como agentes fotosensibilizantes en fotoquimioterapia. |
US6992107B1 (en) | 1995-03-10 | 2006-01-31 | Photocure Asa | Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy |
US6492420B2 (en) | 1995-03-10 | 2002-12-10 | Photocure As | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
US7530461B2 (en) | 1995-03-10 | 2009-05-12 | Photocure Asa | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
GB0018528D0 (en) | 2000-07-27 | 2000-09-13 | Photocure Asa | Compounds |
US6723750B2 (en) | 2002-03-15 | 2004-04-20 | Allergan, Inc. | Photodynamic therapy for pre-melanomas |
CL2008002199A1 (es) | 2007-07-26 | 2009-10-23 | Vitae Pharmaceuticals Inc | Compuestos derivados de 1,3-oxazin-2-ona; composicion farmaceutica que comprende a dichos compuestos; y uso para tratar una enfermedad asociada con la actividad de la 11beta-hidroxiesteroide deshidrogenasa tipo 1 (11beta-hsd1) tales como dislipidemia, hiperlipidemia, hipertension, obesidad y enfermedad cardiovascular, entre otras. |
CL2008003407A1 (es) | 2007-11-16 | 2010-01-11 | Boehringer Ingelheim Int | Compuestos derivados de aril- y heteroarilcarbonilo de heterobiciclo sustituido; composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento y/o prevencion de trastornos metabolicos, mediado por la inhibicion de la enzima hsd-1. |
US8440658B2 (en) | 2007-12-11 | 2013-05-14 | Vitae Pharmaceuticals, Inc. | Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
US8592409B2 (en) | 2008-01-24 | 2013-11-26 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
US8598160B2 (en) | 2008-02-15 | 2013-12-03 | Vitae Pharmaceuticals, Inc. | Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
JP5538365B2 (ja) | 2008-05-01 | 2014-07-02 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状阻害剤 |
TW201004945A (en) | 2008-05-01 | 2010-02-01 | Vitae Pharmaceuticals Inc | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
US8138178B2 (en) | 2008-05-01 | 2012-03-20 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
US8765780B2 (en) | 2008-05-13 | 2014-07-01 | Boehringer Ingelheim International Gmbh | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
WO2010010157A2 (en) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1 |
CN102119160B (zh) | 2008-07-25 | 2014-11-05 | 贝林格尔·英格海姆国际有限公司 | 11β-羟基类固醇脱氢酶1的环状抑制剂 |
MA33216B1 (fr) | 2009-04-30 | 2012-04-02 | Boehringer Ingelheim Int | Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1 |
WO2011011123A1 (en) | 2009-06-11 | 2011-01-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
UY33001A (es) | 2009-11-06 | 2011-05-31 | Boehringer Ingelheim Int | Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina |
JP5860042B2 (ja) | 2010-06-16 | 2016-02-16 | ヴァイティー ファーマシューティカルズ,インコーポレイテッド | 置換5、6及び7員複素環、そのような化合物を含有する医薬及びそれらの使用 |
TWI537258B (zh) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物 |
US8735585B2 (en) | 2011-08-17 | 2014-05-27 | Boehringer Ingelheim International Gmbh | Indenopyridine derivatives |
-
1974
- 1974-03-09 DE DE2411382A patent/DE2411382C3/de not_active Expired
-
1975
- 1975-02-28 AT AT153875A patent/AT344332B/de not_active IP Right Cessation
- 1975-03-05 SU SU7502110984A patent/SU577982A3/ru active
- 1975-03-05 CH CH280275A patent/CH612425A5/xx not_active IP Right Cessation
- 1975-03-06 FI FI750652A patent/FI63571C/fi not_active IP Right Cessation
- 1975-03-07 HU HU75BO1536A patent/HU177408B/hu unknown
- 1975-03-07 DD DD184642A patent/DD119236A5/xx unknown
- 1975-03-07 GB GB9633/75A patent/GB1496418A/en not_active Expired
- 1975-03-07 FR FR7507239A patent/FR2262984B1/fr not_active Expired
- 1975-03-07 RO RO7589653A patent/RO69617A/ro unknown
- 1975-03-07 IL IL46760A patent/IL46760A/xx unknown
- 1975-03-07 NO NO750773A patent/NO141800C/no unknown
- 1975-03-07 SE SE7502592A patent/SE421919B/xx not_active IP Right Cessation
- 1975-03-07 BE BE154138A patent/BE826440A/xx not_active IP Right Cessation
- 1975-03-07 DK DK92975A patent/DK137188C/da active
- 1975-03-07 JP JP50027915A patent/JPS5827275B2/ja not_active Expired
- 1975-03-07 RO RO7589654A patent/RO70051A/ro unknown
- 1975-03-07 ZA ZA751394A patent/ZA751394B/xx unknown
- 1975-03-07 BG BG7500029183A patent/BG25087A3/xx unknown
- 1975-03-07 NL NL7502724A patent/NL7502724A/xx not_active Application Discontinuation
- 1975-03-07 CA CA221,554A patent/CA1049511A/en not_active Expired
- 1975-03-07 IE IE505/75A patent/IE40945B1/xx unknown
- 1975-03-07 BG BG7500030537A patent/BG24813A4/xx unknown
- 1975-03-07 BG BG7500030538A patent/BG24814A4/xx unknown
- 1975-03-08 PL PL1975191318A patent/PL93699B1/pl unknown
- 1975-03-08 PL PL1975191319A patent/PL93700B1/pl unknown
- 1975-03-08 PL PL1975178582A patent/PL93499B1/pl unknown
- 1975-03-10 PH PH16895A patent/PH14127A/en unknown
- 1975-03-10 CS CS751583A patent/CS188221B2/cs unknown
- 1975-08-20 ES ES440349A patent/ES440349A1/es not_active Expired
- 1975-08-20 ES ES440347A patent/ES440347A1/es not_active Expired
- 1975-08-20 ES ES440345A patent/ES440345A1/es not_active Expired
- 1975-08-20 ES ES440350A patent/ES440350A1/es not_active Expired
- 1975-08-20 ES ES440348A patent/ES440348A1/es not_active Expired
- 1975-08-20 ES ES440346A patent/ES440346A1/es not_active Expired
- 1975-12-19 SU SU752199295A patent/SU588916A3/ru active
- 1975-12-19 SU SU7502199294A patent/SU577983A3/ru active
-
1979
- 1979-04-24 CH CH384779A patent/CH622016A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384479A patent/CH622014A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384979A patent/CH622017A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384379A patent/CH620439A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384879A patent/CH620681A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384579A patent/CH622015A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384679A patent/CH620440A5/de not_active IP Right Cessation
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