PL93699B1 - - Google Patents

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Publication number
PL93699B1
PL93699B1 PL1975191318A PL19131875A PL93699B1 PL 93699 B1 PL93699 B1 PL 93699B1 PL 1975191318 A PL1975191318 A PL 1975191318A PL 19131875 A PL19131875 A PL 19131875A PL 93699 B1 PL93699 B1 PL 93699B1
Authority
PL
Poland
Prior art keywords
compounds
formula
methyl
group
pattern
Prior art date
Application number
PL1975191318A
Other languages
English (en)
Polish (pl)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL93699B1 publication Critical patent/PL93699B1/pl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL1975191318A 1974-03-09 1975-03-08 PL93699B1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
PL93699B1 true PL93699B1 (zh) 1977-06-30

Family

ID=5909593

Family Applications (3)

Application Number Title Priority Date Filing Date
PL1975178582A PL93499B1 (zh) 1974-03-09 1975-03-08
PL1975191318A PL93699B1 (zh) 1974-03-09 1975-03-08
PL1975191319A PL93700B1 (zh) 1974-03-09 1975-03-08

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL1975178582A PL93499B1 (zh) 1974-03-09 1975-03-08

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL1975191319A PL93700B1 (zh) 1974-03-09 1975-03-08

Country Status (25)

Country Link
JP (1) JPS5827275B2 (zh)
AT (1) AT344332B (zh)
BE (1) BE826440A (zh)
BG (3) BG24814A4 (zh)
CA (1) CA1049511A (zh)
CH (8) CH612425A5 (zh)
CS (1) CS188221B2 (zh)
DD (1) DD119236A5 (zh)
DE (1) DE2411382C3 (zh)
DK (1) DK137188C (zh)
ES (6) ES440345A1 (zh)
FI (1) FI63571C (zh)
FR (1) FR2262984B1 (zh)
GB (1) GB1496418A (zh)
HU (1) HU177408B (zh)
IE (1) IE40945B1 (zh)
IL (1) IL46760A (zh)
NL (1) NL7502724A (zh)
NO (1) NO141800C (zh)
PH (1) PH14127A (zh)
PL (3) PL93499B1 (zh)
RO (2) RO69617A (zh)
SE (1) SE421919B (zh)
SU (3) SU577982A3 (zh)
ZA (1) ZA751394B (zh)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
EP0820432B1 (en) * 1995-03-10 2001-06-13 PhotoCure ASA Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
CL2008002199A1 (es) 2007-07-26 2009-10-23 Vitae Pharmaceuticals Inc Compuestos derivados de 1,3-oxazin-2-ona; composicion farmaceutica que comprende a dichos compuestos; y uso para tratar una enfermedad asociada con la actividad de la 11beta-hidroxiesteroide deshidrogenasa tipo 1 (11beta-hsd1) tales como dislipidemia, hiperlipidemia, hipertension, obesidad y enfermedad cardiovascular, entre otras.
AR069545A1 (es) 2007-11-16 2010-02-03 Boehringer Ingelheim Pharma Derivados de aril y heteroarilcarbonilo de benzomorfanos y estructuras relacionadas, composiciones farmaceuticas que contienen dichos compuestos, obtencion de las mismas, su uso en el tratamiento de enfermedades mediadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa (hsd) 1 y
JP5490014B2 (ja) 2007-12-11 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の環状尿素阻害剤
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
EP2252601B1 (en) 2008-01-24 2012-12-19 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2254872A2 (en) 2008-02-15 2010-12-01 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
CL2009001058A1 (es) 2008-05-01 2010-09-10 Vitae Pharmaceuticals Inc Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
BRPI0911764A2 (pt) 2008-05-01 2015-10-06 Boehringer Ingelheim Int inibidores cíclicos de 11beta-hidroxiesteroide desigrogenase 1
CA2723034A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
AR071719A1 (es) 2008-05-13 2010-07-07 Boehringer Ingelheim Int Derivados aliciclicos de acido carboxilico de benzomorfanos y estructuras relacionadas, medicamentos que contienen dichos compuestos y su uso.procesos de obtencion
TW201016691A (en) 2008-07-25 2010-05-01 Boehringer Ingelheim Int Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8114868B2 (en) 2008-07-25 2012-02-14 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Also Published As

Publication number Publication date
CH622015A5 (en) 1981-03-13
IL46760A (en) 1978-12-17
PL93700B1 (zh) 1977-06-30
NO141800C (no) 1980-06-04
CH620439A5 (en) 1980-11-28
CS188221B2 (en) 1979-02-28
FR2262984B1 (zh) 1978-07-28
DK92975A (zh) 1975-09-10
PH14127A (en) 1981-02-26
NO141800B (no) 1980-02-04
ES440345A1 (es) 1977-03-01
CH622017A5 (en) 1981-03-13
HU177408B (en) 1981-10-28
DE2411382C3 (de) 1979-09-06
JPS50123675A (zh) 1975-09-29
FI63571B (fi) 1983-03-31
ES440350A1 (es) 1977-03-16
DK137188B (da) 1978-01-30
SU577983A3 (ru) 1977-10-25
FI750652A (zh) 1975-09-10
PL93499B1 (zh) 1977-05-30
CH612425A5 (en) 1979-07-31
CA1049511A (en) 1979-02-27
BE826440A (fr) 1975-09-08
IL46760A0 (en) 1975-05-22
CH620440A5 (en) 1980-11-28
ES440349A1 (es) 1977-03-01
JPS5827275B2 (ja) 1983-06-08
DE2411382A1 (de) 1975-09-18
DE2411382B2 (de) 1979-01-18
RO69617A (ro) 1980-08-15
BG24814A4 (en) 1978-05-12
SU577982A3 (ru) 1977-10-25
ATA153875A (de) 1977-11-15
DK137188C (da) 1978-07-03
DD119236A5 (zh) 1976-04-12
ES440346A1 (es) 1977-03-01
IE40945B1 (en) 1979-09-12
AT344332B (de) 1978-07-10
AU7894275A (en) 1976-09-16
ES440348A1 (es) 1977-06-01
BG24813A4 (en) 1978-05-12
IE40945L (en) 1975-09-09
FR2262984A1 (zh) 1975-10-03
CH622016A5 (en) 1981-03-13
NO750773L (zh) 1975-09-10
GB1496418A (en) 1977-12-30
BG25087A3 (en) 1978-07-12
ZA751394B (en) 1976-11-24
SU588916A3 (ru) 1978-01-15
CH622014A5 (en) 1981-03-13
SE7502592L (zh) 1975-09-10
ES440347A1 (es) 1977-06-01
RO70051A (ro) 1980-12-30
SE421919B (sv) 1982-02-08
FI63571C (fi) 1983-07-11
CH620681A5 (en) 1980-12-15
NL7502724A (nl) 1975-09-11

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