AU704175B2 - Process for preparing {l}- or {d}-homoalanin-4-yl- (methyl)phosphinic acid and salts thereof by racemate resolution - Google Patents

Process for preparing {l}- or {d}-homoalanin-4-yl- (methyl)phosphinic acid and salts thereof by racemate resolution Download PDF

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Publication number
AU704175B2
AU704175B2 AU17595/95A AU1759595A AU704175B2 AU 704175 B2 AU704175 B2 AU 704175B2 AU 17595/95 A AU17595/95 A AU 17595/95A AU 1759595 A AU1759595 A AU 1759595A AU 704175 B2 AU704175 B2 AU 704175B2
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AU
Australia
Prior art keywords
acid
salt
methyl
homoalanin
salts
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Expired
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AU17595/95A
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English (en)
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AU1759595A (en
Inventor
Harald Knorr
Gunter Schlegel
Herbert Stark
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Bayer Intellectual Property GmbH
Original Assignee
Hoechst Schering Agrevo GmbH
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Publication of AU1759595A publication Critical patent/AU1759595A/en
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Publication of AU704175B2 publication Critical patent/AU704175B2/en
Assigned to BAYER CROPSCIENCE AG reassignment BAYER CROPSCIENCE AG Alteration of Name(s) in Register under S187 Assignors: HOECHST SCHERING AGREVO GMBH
Anticipated expiration legal-status Critical
Assigned to BAYER INTELLECTUAL PROPERTY GMBH reassignment BAYER INTELLECTUAL PROPERTY GMBH Alteration of Name(s) in Register under S187 Assignors: BAYER CROPSCIENCE AG
Expired legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/36—Racemisation of optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU17595/95A 1994-03-04 1995-02-24 Process for preparing {l}- or {d}-homoalanin-4-yl- (methyl)phosphinic acid and salts thereof by racemate resolution Expired AU704175B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4407197A DE4407197A1 (de) 1994-03-04 1994-03-04 Verfahren zur Herstellung von /L/-Homoalanin-4-yl-(methyl)phosphinsäure und deren Salze durch Racematspaltung
DEP4407197 1994-03-04
PCT/EP1995/000682 WO1995023805A1 (de) 1994-03-04 1995-02-24 Verfahren zur herstellung von [l]- oder [d]-homoalanin-4-yl-(methyl)phosphinsäure und deren salzen durch racematspaltung

Publications (2)

Publication Number Publication Date
AU1759595A AU1759595A (en) 1995-09-18
AU704175B2 true AU704175B2 (en) 1999-04-15

Family

ID=6511844

Family Applications (1)

Application Number Title Priority Date Filing Date
AU17595/95A Expired AU704175B2 (en) 1994-03-04 1995-02-24 Process for preparing {l}- or {d}-homoalanin-4-yl- (methyl)phosphinic acid and salts thereof by racemate resolution

Country Status (19)

Country Link
US (2) US5767309A (enrdf_load_html_response)
EP (1) EP0748325B1 (enrdf_load_html_response)
JP (1) JP4303785B2 (enrdf_load_html_response)
CN (1) CN1053669C (enrdf_load_html_response)
AT (1) ATE176475T1 (enrdf_load_html_response)
AU (1) AU704175B2 (enrdf_load_html_response)
BR (1) BR9506986A (enrdf_load_html_response)
CA (1) CA2184718A1 (enrdf_load_html_response)
CZ (1) CZ260196A3 (enrdf_load_html_response)
DE (2) DE4407197A1 (enrdf_load_html_response)
ES (1) ES2128717T3 (enrdf_load_html_response)
FI (1) FI963422A7 (enrdf_load_html_response)
HU (1) HU215583B (enrdf_load_html_response)
IL (1) IL112851A (enrdf_load_html_response)
MX (1) MX9603873A (enrdf_load_html_response)
TR (1) TR28265A (enrdf_load_html_response)
TW (1) TW293012B (enrdf_load_html_response)
WO (1) WO1995023805A1 (enrdf_load_html_response)
ZA (1) ZA951779B (enrdf_load_html_response)

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KR100332399B1 (ko) * 1999-02-22 2002-04-13 김경호 메토프롤롤 라세미체로부터 메토프롤롤 에난티오머의 제조방법
DE19955283A1 (de) * 1999-11-17 2001-05-23 Aventis Res & Tech Gmbh & Co Verfahren zur enantioselektiven Gewinnung von Aminosäuren und Aminosäurederivaten unter Verwendung von Racemisierungskatalysatoren
US7879824B2 (en) 2001-07-31 2011-02-01 Dermal Research Laboratories, Inc. Methods of preventing or treating diseases and conditions using complex carbohydrates
BR112018067523A8 (pt) 2016-03-02 2023-01-31 Agrimetis Llc Métodos para preparar l-glufosinato
CN106188134B (zh) * 2016-07-01 2018-03-20 永农生物科学有限公司 一种l‑草铵膦或其盐的分离及精制方法
WO2018108794A1 (de) 2016-12-15 2018-06-21 Bayer Cropscience Aktiengesellschaft Verfahren zur herstellung von d-glufosinat oder dessen salzen unter verwendung von ephedrin
WO2018108797A1 (de) 2016-12-15 2018-06-21 Bayer Cropscience Aktiengesellschaft Verfahren zur herstellung von l-glufosinat oder dessen salzen unter verwendung von ephedrin
WO2018193999A1 (ja) 2017-04-17 2018-10-25 国立大学法人京都大学 光学活性な２－アミノ－ホスホノアルカン酸、光学活性な２－アミノ－ホスホノアルカン酸塩、及びこれらの水和物
CA3070104C (en) * 2017-07-18 2023-08-08 Agrimetis, Llc Methods for the purification of l-glufosinate and crystalline l-glufosinate ammonium forms
CN110343676B (zh) 2018-04-03 2020-06-23 上海弈柯莱生物医药科技有限公司 一种l-谷氨酸脱氢酶突变体及其应用
CN110467580B (zh) * 2018-05-10 2020-11-13 华润赛科药业有限责任公司 雷西纳德轴手性对映体的拆分方法
EP3847269A1 (en) 2018-09-05 2021-07-14 Basf Se Methods for improving yields of l-glufosinate
CN111072718A (zh) * 2018-10-19 2020-04-28 中国药科大学 一种l－草铵膦的制备方法
CN109369713A (zh) * 2018-12-18 2019-02-22 山东省农药科学研究院 一种精草铵膦酸水合物晶体及其制备方法
US12234254B2 (en) 2019-04-16 2025-02-25 Basf Se Methods for producing crystalline L-glufosinate ammonium monohydrate
CN111979208B (zh) 2019-05-23 2023-01-10 弈柯莱生物科技(上海)股份有限公司 一种l-谷氨酸脱氢酶突变体及其应用
WO2022024052A1 (en) * 2020-07-31 2022-02-03 Upl Limited Crystalline form of l-glufosinate ammonium salt and process for production thereof
US11555046B2 (en) 2020-07-31 2023-01-17 Upl Ltd Crystalline form of L-glufosinate ammonium salt and process for production thereof
CN113234767B (zh) * 2021-05-13 2022-05-17 永农生物科学有限公司 制备不含结晶水的l-草铵膦铵盐的固体粉末的方法
BR112023026056A2 (pt) * 2021-06-11 2024-03-05 Upl Ltd Um método para obter l-glufosinato
JP2024546729A (ja) 2021-12-10 2024-12-26 ビーエーエスエフ ソシエタス・ヨーロピア ヒダントイナーゼをベースとするプロセスを使用するグルホシネートの合成
MX2024007021A (es) 2021-12-10 2024-06-19 Basf Se Descarbamoilacion enzimatica de derivados de glufosinato.
WO2023236168A1 (zh) * 2022-06-10 2023-12-14 江苏七洲绿色科技研究院有限公司 L-草铵膦铵盐的结晶及其制备方法和应用
WO2024158883A1 (en) * 2023-01-25 2024-08-02 Vulpes Agricultural Corp. Optically active amino acid salts and method for their preparation
TW202437917A (zh) 2023-02-23 2024-10-01 德商巴地斯顏料化工廠 由羥腈或羥腈衍生物製備l-固殺草之方法
AR132932A1 (es) 2023-06-13 2025-08-13 Basf Se Síntesis de glufosinato mediante un proceso basado en amidasa

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0057092A1 (en) * 1981-01-23 1982-08-04 Tanabe Seiyaku Co., Ltd. Process for racemizing an optically active alpha-amino acid or a salt thereof
EP0382113B1 (de) * 1989-02-06 1994-09-21 Hoechst Schering AgrEvo GmbH Verfahren zur enzymatischen Trennung von 2-Amino-4-methylphosphinobuttersäurederivaten

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US3213106A (en) * 1961-11-16 1965-10-19 Ajinomoto Kk Process of racemizing optically active alpha acids
CH551945A (de) * 1970-07-16 1974-07-31 Ciba Geigy Ag Verfahren zur herstellung der (+)-(beta)-amino-(beta)-(3,4-dimethoxy-phenyl)-propionsaeure.
GB2011416B (en) * 1977-12-28 1982-10-20 Meiji Seika Kaisha Herbicidal compositions
GB8421964D0 (en) * 1984-08-30 1984-10-03 Beecham Group Plc Chemical process
DE3542645A1 (de) * 1985-12-03 1987-06-04 Hoechst Ag Verfahren zur herstellung von l-homoalanin-4-yl(methyl)-phosphinsaeure sowie ihrer alkylester
DE3609818A1 (de) * 1986-03-22 1987-09-24 Hoechst Ag Verfahren zur herstellung von l-phosphinothricin(derivaten) sowie ihrer alkylester
DE3706022A1 (de) * 1987-02-25 1988-09-08 Hoechst Ag Verfahren zur racemisierung von optisch aktiver d-2-phenacetylamino-4-methylphosphinobuttersaeure
DE3817191A1 (de) * 1988-05-20 1989-11-30 Hoechst Ag Verfahren zur racemisierung von optisch aktiver d-2-n-phenacetylamino-4- methylphosphinobuttersaeure
DE3817956A1 (de) * 1988-05-27 1989-12-07 Hoechst Ag Verfahren zur herstellung phosphorhaltiger l-aminosaeuren sowie ihrer ester und n-derivate
DE3920570A1 (de) * 1989-06-23 1991-01-03 Hoechst Ag Verfahren zur isolierung von l-2-amino-4-methylphosphinobuttersaeure-ammoniumsalz aus einer enzymatischen transaminierungsloesung
DE3923650A1 (de) * 1989-07-18 1991-01-31 Hoechst Ag Verfahren zur gewinnung von l-2-amino-4-methylphosphinobuttersaeure-(salzen) durch elektrodialyse
IL98502A (en) * 1990-06-22 1998-04-05 Ciba Geigy Ag Aminoalkane phosphinic acid derivatives, process for their preparation and pharmaceutical compositions containing them
EP0499376A1 (en) * 1991-01-31 1992-08-19 Hoechst Celanese Corporation Precipitation-induced asymmetric transformation of chiral alpha-amino acids and salts thereof
TW353663B (en) * 1991-04-06 1999-03-01 Hoechst Ag Process for the preparation of phosphorus-containing L-amino acids, their derivatives and intermediates for this process
DE9202282U1 (de) * 1991-04-09 1992-04-30 Siemens AG, 8000 München Schiebeschalter
ZA925776B (en) * 1991-08-03 1993-04-28 Hoechst Ag Optically active omega-halo-2-aminoalkanecarboxylic acid derivatives,process for the preparation thereof and their use for the preparation of optically active phosphorus-containing alpha-amino acids
JPH05165305A (ja) * 1991-12-11 1993-07-02 Sharp Corp 帯電装置
IL104056A (en) * 1991-12-13 1997-02-18 Hoechst Ag Process for the preparation of L-phosphinothricin and its derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0057092A1 (en) * 1981-01-23 1982-08-04 Tanabe Seiyaku Co., Ltd. Process for racemizing an optically active alpha-amino acid or a salt thereof
EP0382113B1 (de) * 1989-02-06 1994-09-21 Hoechst Schering AgrEvo GmbH Verfahren zur enzymatischen Trennung von 2-Amino-4-methylphosphinobuttersäurederivaten

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEM ABS VOL 68 NO 3 15 JAN 1968 ABSTRACT NO 13342 *

Also Published As

Publication number Publication date
JPH09509924A (ja) 1997-10-07
CA2184718A1 (en) 1995-09-08
FI963422A0 (fi) 1996-09-02
IL112851A0 (en) 1995-06-29
CN1143369A (zh) 1997-02-19
HU215583B (hu) 1999-01-28
WO1995023805A1 (de) 1995-09-08
ES2128717T3 (es) 1999-05-16
CZ260196A3 (en) 1997-02-12
MX9603873A (es) 1997-03-29
IL112851A (en) 2000-08-13
US5869668A (en) 1999-02-09
HU9602411D0 (en) 1996-11-28
ATE176475T1 (de) 1999-02-15
JP4303785B2 (ja) 2009-07-29
AU1759595A (en) 1995-09-18
FI963422L (fi) 1996-09-02
HUT75050A (en) 1997-03-28
TR28265A (tr) 1996-04-09
CN1053669C (zh) 2000-06-21
FI963422A7 (fi) 1996-09-02
DE4407197A1 (de) 1995-09-07
TW293012B (enrdf_load_html_response) 1996-12-11
ZA951779B (en) 1995-11-09
DE59505034D1 (de) 1999-03-18
BR9506986A (pt) 1997-09-16
EP0748325B1 (de) 1999-02-03
US5767309A (en) 1998-06-16
EP0748325A1 (de) 1996-12-18

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