AU679774B2 - Piperidines and piperazines - Google Patents

Piperidines and piperazines Download PDF

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Publication number
AU679774B2
AU679774B2 AU74244/94A AU7424494A AU679774B2 AU 679774 B2 AU679774 B2 AU 679774B2 AU 74244/94 A AU74244/94 A AU 74244/94A AU 7424494 A AU7424494 A AU 7424494A AU 679774 B2 AU679774 B2 AU 679774B2
Authority
AU
Australia
Prior art keywords
formula
piperazine
butyl
compound
ind
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU74244/94A
Other languages
English (en)
Other versions
AU7424494A (en
Inventor
Gerd Dr. Bartoszyk
Henning Dr. Bottcher
Hartmut Dr. Greiner
Christoph Dr. Seyfried
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of AU7424494A publication Critical patent/AU7424494A/en
Application granted granted Critical
Publication of AU679774B2 publication Critical patent/AU679774B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AU74244/94A 1993-09-30 1994-09-27 Piperidines and piperazines Expired AU679774B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4333254A DE4333254A1 (de) 1993-09-30 1993-09-30 Piperidine und Piperazine
DE4333254 1993-09-30

Publications (2)

Publication Number Publication Date
AU7424494A AU7424494A (en) 1995-04-13
AU679774B2 true AU679774B2 (en) 1997-07-10

Family

ID=6499013

Family Applications (1)

Application Number Title Priority Date Filing Date
AU74244/94A Expired AU679774B2 (en) 1993-09-30 1994-09-27 Piperidines and piperazines

Country Status (21)

Country Link
US (1) US5532241A (cg-RX-API-DMAC10.html)
EP (1) EP0648767B1 (cg-RX-API-DMAC10.html)
JP (2) JP4065034B2 (cg-RX-API-DMAC10.html)
KR (1) KR100341190B1 (cg-RX-API-DMAC10.html)
CN (1) CN1056610C (cg-RX-API-DMAC10.html)
AT (1) ATE153663T1 (cg-RX-API-DMAC10.html)
AU (1) AU679774B2 (cg-RX-API-DMAC10.html)
CA (1) CA2133152C (cg-RX-API-DMAC10.html)
CZ (1) CZ293558B6 (cg-RX-API-DMAC10.html)
DE (2) DE4333254A1 (cg-RX-API-DMAC10.html)
DK (1) DK0648767T3 (cg-RX-API-DMAC10.html)
ES (1) ES2105454T3 (cg-RX-API-DMAC10.html)
GR (1) GR3024551T3 (cg-RX-API-DMAC10.html)
HU (1) HU218918B (cg-RX-API-DMAC10.html)
NO (1) NO306948B1 (cg-RX-API-DMAC10.html)
PL (1) PL178137B1 (cg-RX-API-DMAC10.html)
RU (1) RU2132848C1 (cg-RX-API-DMAC10.html)
SK (1) SK281793B6 (cg-RX-API-DMAC10.html)
TW (1) TW313569B (cg-RX-API-DMAC10.html)
UA (1) UA34449C2 (cg-RX-API-DMAC10.html)
ZA (1) ZA947622B (cg-RX-API-DMAC10.html)

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TR201702104A2 (tr) 2017-02-13 2018-08-27 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Vi̇lazodon hi̇droklorür farmasöti̇k bi̇leşi̇mleri̇
TR201702103A2 (tr) 2017-02-13 2018-08-27 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Vilazodon hi̇droklorürün tablet formlari
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CN111454250B (zh) * 2019-01-21 2021-05-07 华东理工大学 多靶点活性化合物及其用途
CN120817935A (zh) * 2024-04-15 2025-10-21 复旦大学附属肿瘤医院 一种杂(芳)环取代环状二胺类化合物及其在制备治疗和/或预防肿瘤药物中的应用

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Also Published As

Publication number Publication date
NO943616L (no) 1995-03-31
JPH07149762A (ja) 1995-06-13
HUT71833A (en) 1996-02-28
RU2132848C1 (ru) 1999-07-10
UA34449C2 (uk) 2001-03-15
KR950008510A (ko) 1995-04-17
CZ293558B6 (cs) 2004-06-16
CA2133152A1 (en) 1995-03-31
DK0648767T3 (da) 1997-12-22
CA2133152C (en) 2005-08-30
GR3024551T3 (en) 1997-12-31
AU7424494A (en) 1995-04-13
DE59402902D1 (de) 1997-07-03
JP4700017B2 (ja) 2011-06-15
SK118494A3 (en) 1995-05-10
PL178137B1 (pl) 2000-03-31
PL305216A1 (en) 1995-04-03
CN1106811A (zh) 1995-08-16
ATE153663T1 (de) 1997-06-15
TW313569B (cg-RX-API-DMAC10.html) 1997-08-21
JP2007119502A (ja) 2007-05-17
KR100341190B1 (ko) 2002-11-13
RU94035660A (ru) 1996-07-20
DE4333254A1 (de) 1995-04-06
EP0648767A1 (de) 1995-04-19
US5532241A (en) 1996-07-02
NO306948B1 (no) 2000-01-17
EP0648767B1 (de) 1997-05-28
ZA947622B (en) 1995-05-16
HU218918B (hu) 2000-12-28
HU9402806D0 (en) 1995-01-30
ES2105454T3 (es) 1997-10-16
CN1056610C (zh) 2000-09-20
CZ237094A3 (en) 1995-04-12
JP4065034B2 (ja) 2008-03-19
NO943616D0 (no) 1994-09-29
SK281793B6 (sk) 2001-08-06

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