AU2020405446A1 - Compounds active towards nuclear receptors - Google Patents

Compounds active towards nuclear receptors Download PDF

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Publication number
AU2020405446A1
AU2020405446A1 AU2020405446A AU2020405446A AU2020405446A1 AU 2020405446 A1 AU2020405446 A1 AU 2020405446A1 AU 2020405446 A AU2020405446 A AU 2020405446A AU 2020405446 A AU2020405446 A AU 2020405446A AU 2020405446 A1 AU2020405446 A1 AU 2020405446A1
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AU
Australia
Prior art keywords
fluoro
methyl
amino
acetamide
trifluoromethyl
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Pending
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AU2020405446A
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English (en)
Inventor
Thomas Franch
Alex Haahr Gouliaev
Søren Jensby NIELSEN
Ian SARVARY
Sanne SCHRØDER GLAD
Luigi Piero Stasi
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Nuevolution AS
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Nuevolution AS
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Publication of AU2020405446A1 publication Critical patent/AU2020405446A1/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2020405446A 2019-12-20 2020-12-18 Compounds active towards nuclear receptors Pending AU2020405446A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962951239P 2019-12-20 2019-12-20
US62/951,239 2019-12-20
PCT/IB2020/062224 WO2021124277A1 (en) 2019-12-20 2020-12-18 Compounds active towards nuclear receptors

Publications (1)

Publication Number Publication Date
AU2020405446A1 true AU2020405446A1 (en) 2022-05-26

Family

ID=74003833

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020405446A Pending AU2020405446A1 (en) 2019-12-20 2020-12-18 Compounds active towards nuclear receptors

Country Status (6)

Country Link
US (1) US11447479B2 (https=)
EP (1) EP4076657A1 (https=)
JP (1) JP2021098692A (https=)
AU (1) AU2020405446A1 (https=)
MX (1) MX2022007265A (https=)
WO (1) WO2021124277A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11685727B2 (en) 2019-12-20 2023-06-27 Nuevolution A/S Compounds active towards nuclear receptors
CA3174176A1 (en) 2020-03-31 2021-10-07 Sanne Schroder Glad Compounds active towards nuclear receptors
EP4126874A1 (en) 2020-03-31 2023-02-08 Nuevolution A/S Compounds active towards nuclear receptors
CN113461687B (zh) * 2021-08-10 2022-04-19 四川大学华西医院 2,8-氮杂-[4,5]十螺环酮衍生物及其制备方法和用途
CN119060034B (zh) * 2024-09-02 2026-03-24 上海信诺维生物医药有限公司 一种含吡喃取代的吗啉类化合物的制备方法

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