AU2019312692B2 - Muscle targeting complexes and uses thereof for treating dystrophinopathies - Google Patents

Muscle targeting complexes and uses thereof for treating dystrophinopathies

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Publication number
AU2019312692B2
AU2019312692B2 AU2019312692A AU2019312692A AU2019312692B2 AU 2019312692 B2 AU2019312692 B2 AU 2019312692B2 AU 2019312692 A AU2019312692 A AU 2019312692A AU 2019312692 A AU2019312692 A AU 2019312692A AU 2019312692 B2 AU2019312692 B2 AU 2019312692B2
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Prior art keywords
antibody
transferrin receptor
oligonucleotide
muscle
complex
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AU2019312692A
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AU2019312692A1 (en
Inventor
Mohammed T. QATANANI
Romesh R. Subramanian
Timothy Weeden
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Dyne Therapeutics Inc
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Dyne Therapeutics Inc
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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AU2019312692A 2018-08-02 2019-08-02 Muscle targeting complexes and uses thereof for treating dystrophinopathies Active AU2019312692B2 (en)

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US201862714031P 2018-08-02 2018-08-02
US62/714,031 2018-08-02
US201962855766P 2019-05-31 2019-05-31
US62/855,766 2019-05-31
PCT/US2019/044949 WO2020028832A1 (en) 2018-08-02 2019-08-02 Muscle targeting complexes and uses thereof for treating dystrophinopathies

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AU2019312692B2 true AU2019312692B2 (en) 2026-06-11

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