AU2018372631B2 - Cellular compositions and methods of treatment I - Google Patents

Cellular compositions and methods of treatment I Download PDF

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AU2018372631B2
AU2018372631B2 AU2018372631A AU2018372631A AU2018372631B2 AU 2018372631 B2 AU2018372631 B2 AU 2018372631B2 AU 2018372631 A AU2018372631 A AU 2018372631A AU 2018372631 A AU2018372631 A AU 2018372631A AU 2018372631 B2 AU2018372631 B2 AU 2018372631B2
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mir
hsa
cells
cell
mesenchymal lineage
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AU2018372631A1 (en
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Peter Brink
Ira Cohen
Dan Devine
Sergey DORONIN
Silviu Itescu
Richard Lin
Nick Loizos
Irina Potapova
Anthony Sandrasagra
Virginijus VALIUNAS
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Mesoblast International SARL
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    • A61K31/7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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    • C12Y204/00Glycosyltransferases (2.4)
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    • C12Y204/01214Glycoprotein 3-alpha-L-fucosyltransferase (2.4.1.214)
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    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
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AU2018372631A 2017-11-22 2018-11-21 Cellular compositions and methods of treatment I Active AU2018372631B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762589764P 2017-11-22 2017-11-22
US62/589,764 2017-11-22
PCT/IB2018/001439 WO2019102268A1 (en) 2017-11-22 2018-11-21 Cellular compositions and methods of treatment i

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AU2018372631A1 AU2018372631A1 (en) 2020-05-21
AU2018372631B2 true AU2018372631B2 (en) 2025-06-05

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US (2) US12473547B2 (https=)
EP (1) EP3714038A1 (https=)
JP (2) JP7463275B2 (https=)
KR (2) KR20250051794A (https=)
CN (2) CN119033819A (https=)
AU (1) AU2018372631B2 (https=)
BR (1) BR112020010079A2 (https=)
CA (1) CA3084575A1 (https=)
SG (1) SG11202004680UA (https=)
WO (1) WO2019102268A1 (https=)

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CN119033819A (zh) 2017-11-22 2024-11-29 迈索布拉斯特国际有限公司 细胞组合物及治疗方法
US12584126B2 (en) * 2018-09-11 2026-03-24 Helmholtz Zentrum Muenchen—Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt (Gmbh) microRNA inhibitors for use in treating metabolic diseases
CN113667753B (zh) * 2020-03-30 2022-03-22 中国医学科学院肿瘤医院 用于肺癌诊断的试剂盒、装置及方法
CN112067805B (zh) * 2020-08-25 2023-08-22 南通大学 一种β-1,4-半乳糖基转移酶-IsiRNA在克服肝癌化疗耐药药物中的应用
CN113025714B (zh) * 2021-03-23 2022-05-24 华中科技大学同济医学院附属同济医院 用于甲状腺乳头状癌颈侧方淋巴结转移诊断的miRNA生物标志物及检测试剂盒
US20240342280A1 (en) * 2021-08-09 2024-10-17 The Trustees Of The University Of Pennsylvania Optimizing t cell differentiation state with micrornas
CN114085817B (zh) * 2021-11-26 2025-04-15 三代康年(上海)医疗科技有限公司 一种包载microRNA的外泌体的制备方法及其产品和应用
US20250333758A1 (en) * 2021-12-15 2025-10-30 Genans Biotechnology Co., Ltd Microglia having car and use thereof
WO2024196812A1 (en) * 2023-03-20 2024-09-26 MAM Holdings of West Florida, L.L.C. Mesenchymal stem cell-derived micro-ribonucleic acid-mediated treatments for the prevention and targeted treatment of cancer and other disorders
CN118831092A (zh) * 2024-09-19 2024-10-25 天津市第五中心医院 miR-200b-3p在制备治疗子宫内膜癌的药物中的应用
CN119144728B (zh) * 2024-11-19 2025-04-29 四川大学华西医院 原发性肝癌的MicroRNA标志物的引物、试剂盒和应用

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