DE60143517D1 - Wiederherstellung der gelenken mit mesenchymalen stammzellen - Google Patents
Wiederherstellung der gelenken mit mesenchymalen stammzellenInfo
- Publication number
- DE60143517D1 DE60143517D1 DE60143517T DE60143517T DE60143517D1 DE 60143517 D1 DE60143517 D1 DE 60143517D1 DE 60143517 T DE60143517 T DE 60143517T DE 60143517 T DE60143517 T DE 60143517T DE 60143517 D1 DE60143517 D1 DE 60143517D1
- Authority
- DE
- Germany
- Prior art keywords
- stem cells
- mesenchymal stem
- races
- restoring
- joint
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30756—Cartilage endoprostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/38—Joints for elbows or knees
- A61F2/3872—Meniscus for implantation between the natural bone surfaces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19954900P | 2000-04-25 | 2000-04-25 | |
US23610600P | 2000-09-28 | 2000-09-28 | |
PCT/US2001/013267 WO2001080865A2 (en) | 2000-04-25 | 2001-04-24 | Joint repair using mesenchymal stem cells |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60143517D1 true DE60143517D1 (de) | 2011-01-05 |
Family
ID=26894885
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60143517T Expired - Lifetime DE60143517D1 (de) | 2000-04-25 | 2001-04-24 | Wiederherstellung der gelenken mit mesenchymalen stammzellen |
Country Status (10)
Country | Link |
---|---|
US (5) | US20020005205A1 (de) |
EP (1) | EP1276486B2 (de) |
JP (4) | JP5090604B2 (de) |
AT (1) | ATE489101T1 (de) |
AU (2) | AU2001257236B2 (de) |
CA (1) | CA2405345C (de) |
DE (1) | DE60143517D1 (de) |
ES (1) | ES2353061T5 (de) |
PT (1) | PT1276486E (de) |
WO (1) | WO2001080865A2 (de) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020005205A1 (en) * | 2000-04-25 | 2002-01-17 | Barry Francis P. | Joint repair using mesenchymal stem cells |
DE10139783C1 (de) * | 2001-08-14 | 2003-04-17 | Transtissue Technologies Gmbh | Zellzusammensetzungen zur Behandlung von Osteoarthrose, sowie Verfahren zu deren Herstellung |
CA2468335C (en) * | 2001-12-07 | 2014-07-08 | Geron Corporation | Chondrocyte precursors derived from human embryonic stem cells |
AR047712A1 (es) * | 2002-09-07 | 2006-02-15 | Royal Veterinary College | Metodo de tratamiento de una lesion de tejido esqueletico blando natural administrando una composicion de celulas madre mesenquimatosas |
WO2005035742A2 (en) * | 2003-10-08 | 2005-04-21 | Vet-Stem Inc. | Methods of preparing and using stem cell compositions and kits comprising the same |
US8012693B2 (en) * | 2003-12-16 | 2011-09-06 | 3M Innovative Properties Company | Analysis of chemically crosslinked cellular samples |
AU2015252160A1 (en) * | 2004-03-22 | 2015-11-26 | Mesoblast International Sarl | Mesenchymal stem cells and uses therefor |
EP2298862B1 (de) | 2004-03-22 | 2017-08-30 | Mesoblast International Sàrl | Mesenchymale Stammzellen und deren Verwendungen |
AU2012205269B2 (en) * | 2004-03-22 | 2015-08-27 | Mesoblast International Sarl | Mesenchymal stem cells and uses therefor |
ATE556134T1 (de) * | 2004-03-22 | 2012-05-15 | Osiris Therapeutics Inc | Mesenchymstammzellen und verwendungendafür |
US8697139B2 (en) | 2004-09-21 | 2014-04-15 | Frank M. Phillips | Method of intervertebral disc treatment using articular chondrocyte cells |
AU2006261624B2 (en) * | 2005-06-16 | 2012-02-02 | Solventum Intellectual Properties Company | Method of classifying chemically crosslinked cellular samples using mass spectra |
US20090035257A1 (en) * | 2005-08-25 | 2009-02-05 | Repair Technologies, Inc. | Devices, compositions and methods for the protection and repair of cells and tissues |
GB0600972D0 (en) * | 2006-01-18 | 2006-03-01 | Univ Leeds | Enrichment of cells |
MY154677A (en) | 2006-03-07 | 2015-07-15 | Shroff Geeta | Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation |
US20080260703A1 (en) * | 2007-04-23 | 2008-10-23 | Medistem Labortories | Treatment of Insulin Resistance and Diabetes |
US9095562B2 (en) * | 2007-07-05 | 2015-08-04 | Regenerative Sciences, Inc. | Methods and compositions for optimized expansion and implantation of mesenchymal stem cells |
AU2013203054B2 (en) * | 2007-08-06 | 2017-05-18 | Mesoblast, Inc. | Methods of generating, repairing and/or maintaining connective tissue in vivo |
TR201821239T4 (tr) * | 2007-08-06 | 2019-01-21 | Mesoblast Inc | Bağ dokusu hastalıklarının tedavisinde kullanım için stro-1 parlak hücreler. |
WO2009018613A1 (en) * | 2007-08-06 | 2009-02-12 | Angioblast Systems, Inc. | Methods of generating, repairing and/or maintaining connective tissue in vivo |
WO2009085969A2 (en) | 2007-12-19 | 2009-07-09 | Regenerative Sciences, Llc | Compositions and methods to promote implantation and engrafment of stem cells |
JP2011512345A (ja) | 2008-02-15 | 2011-04-21 | ボーン・セラピューティクス | 骨関節疾患の治療及び/または予防において使用する医薬組成物 |
EP2090308A1 (de) * | 2008-02-15 | 2009-08-19 | Bone Therapeutics | Pharmazeutische Zusammensetzung zur Behandlung oder Verhinderung von Knochengelenkserkrankungen |
BRPI0905715A2 (pt) | 2008-02-15 | 2015-07-14 | Bone Therapeutics | Composição farmacêutica e kit de componentes |
EP2257176B1 (de) | 2008-03-14 | 2013-09-18 | Regenerative Sciences, LLC | Zusammensetzungen und verfahren zur knorpelreparatur |
ES2692879T3 (es) | 2008-06-25 | 2018-12-05 | Mesoblast, Inc. | Reparación y/o reconstitución de discos invertebrales |
US8343480B2 (en) * | 2008-11-14 | 2013-01-01 | Howmedica Osteonics Corp. | Administration of stem or progenitor cells to a joint to enhance recovery from joint surgery |
US9192695B2 (en) | 2008-11-20 | 2015-11-24 | Allosource | Allografts combined with tissue derived stem cells for bone healing |
JP2012510874A (ja) | 2008-12-05 | 2012-05-17 | リジェネレイティブ サイエンシーズ, エルエルシー | 無血管組織の修復を促進するための方法及び組成物 |
WO2010099463A2 (en) | 2009-02-27 | 2010-09-02 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Joint bioscaffolds |
IT1394570B1 (it) | 2009-07-02 | 2012-07-05 | Fidia Farmaceutici | Materiale biologico adatto per la terapia dell osteoartrosi del danno dei legamenti e per il trattamento delle patologie delle articolazioni. |
CA2777783A1 (en) * | 2009-10-13 | 2011-04-21 | Allocure Inc. | Assay for the prediction of therapeutic effectiveness of mesenchymal stromal cells, and methods of using same |
US9113950B2 (en) | 2009-11-04 | 2015-08-25 | Regenerative Sciences, Llc | Therapeutic delivery device |
CN103180435A (zh) * | 2010-08-31 | 2013-06-26 | 库克通用生物技术有限责任公司 | 用于治疗动物疾病的全身的同种异体干细胞疗法 |
US8709401B2 (en) | 2011-02-25 | 2014-04-29 | Howmedica Osteonics Corp. | Primed stem cells and uses thereof to treat inflammatory conditions in joints |
CN103930542A (zh) | 2011-06-29 | 2014-07-16 | 生物修复疗法有限公司 | 棕色脂肪细胞组合物及方法 |
GB201202319D0 (en) | 2012-02-10 | 2012-03-28 | Orbsen Therapeutics Ltd | Stromal stem cells |
US9457051B2 (en) * | 2013-01-22 | 2016-10-04 | Animal Cell Therapies, Inc. | Use of stem cells or progenitor cells to treat, delay, prevent, or repair tearing of cruciate ligaments |
DK2956543T3 (da) | 2013-02-12 | 2019-01-02 | Replicel Life Sciences Inc | Sammensætninger og fremgangsmåder til behandling og reparation af sener |
WO2014130883A2 (en) | 2013-02-22 | 2014-08-28 | Allosource | Cartilage mosaic compositions and methods |
WO2014150784A1 (en) | 2013-03-15 | 2014-09-25 | Allosource | Cell repopulated collagen matrix for soft tissue repair and regeneration |
KR102138399B1 (ko) | 2013-03-15 | 2020-07-27 | 알로소스 | 천공된 골연골 동종이식 조성물 |
US20150010606A1 (en) * | 2013-07-08 | 2015-01-08 | Arthrex, Inc. | Intra-articular injection and implant attachment of molecule consisting of lubricin and extracellular superoxide dismutase or hyaluronic acid and extracellular superoxide dismutase |
US9597099B2 (en) * | 2013-07-29 | 2017-03-21 | Covidien Lp | Energy-based treatment methods for refractory gout |
JP6191694B2 (ja) * | 2013-08-01 | 2017-09-06 | 株式会社ツーセル | 軟骨損傷治療剤及びその製造方法 |
WO2015116707A1 (en) | 2014-01-28 | 2015-08-06 | Medivation Technologies, Inc. | Targeted therapeutics |
EP3074506A1 (de) | 2014-02-12 | 2016-10-05 | National University of Ireland, Galway | Auswahl und verwendung von stammzellen |
WO2015123477A1 (en) * | 2014-02-12 | 2015-08-20 | Replicel Life Sciences Inc. | Compositions and methods for treating bone, joints and cartilage |
RU2559089C1 (ru) * | 2014-04-22 | 2015-08-10 | Государственное автономное учреждение здравоохранения "Республиканская клиническая больница Министерства здравоохранения Республики Татарстан" | Способ восстановления дефектов гиалинового хряща суставных поверхностей суставов конечностей |
WO2016015007A1 (en) | 2014-07-25 | 2016-01-28 | Recellerate, Inc. | Methods of treating exercise-induced pulmonary hemorrhage |
TWI566774B (zh) * | 2014-10-06 | 2017-01-21 | 佛教慈濟醫療財團法人花蓮慈濟醫院 | 治療關節疾病的組成物及其方法 |
RU2644650C2 (ru) | 2014-12-01 | 2018-02-13 | Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" | Материал стволовых клеток и способ его получения |
WO2017019832A1 (en) | 2015-07-29 | 2017-02-02 | Medivation Technologies, Inc. | Methods and compositions using repair cells and cationic dyes |
KR101720329B1 (ko) | 2015-12-11 | 2017-03-28 | 주식회사 에이티앤씨 | 무선통신 단말기용 nfc 및 mst 공용 안테나 장치 |
RU2708329C2 (ru) | 2016-05-31 | 2019-12-05 | Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" | Материал стволовых клеток, композиции и способы применения |
CN106075585B (zh) * | 2016-07-08 | 2019-06-21 | 福建师范大学 | 一种基于人工肌腱支架材料的组织工程化人工肌腱移植物的制备方法 |
EP3522984A1 (de) * | 2016-10-07 | 2019-08-14 | Cytori Therapeutics, Inc. | Regenerative zelltherapie für erkrankungen des bewegungsapparats |
US9980984B2 (en) | 2016-10-13 | 2018-05-29 | Kenneth Allen Pettine | Treatment of inflammation of osteoarthritic knees with mesenchymal stem cells |
US11401502B2 (en) | 2016-11-15 | 2022-08-02 | Kaneka Corporation | Cell population comprising mesenchymal stem cells derived from fetal appendage, method for producing the same, and pharmaceutical composition |
KR102580320B1 (ko) | 2017-01-27 | 2023-09-19 | 신텔라 에이비 | 골 및 연골 손상 또는 질환의 예방 및 치료 |
JP7454379B2 (ja) | 2017-12-28 | 2024-03-22 | 株式会社カネカ | 接着性幹細胞を含む細胞集団とその製造方法、及び医薬組成物 |
EP3720948A1 (de) | 2018-03-12 | 2020-10-14 | Universidade do Porto | Zusammensetzungen zur verwendung bei der behandlung von muskel-skelett-erkrankungen und verfahren zur herstellung derselben für die verstärkung der synergistischen wirkung von zwei verschiedenen arten von mesenchymalen stroma-/stammzellen |
WO2020251020A1 (ja) | 2019-06-14 | 2020-12-17 | 株式会社カネカ | 間葉系細胞を含む細胞集団、それを含む医薬組成物、及び、その製造方法 |
US11583402B2 (en) | 2019-07-16 | 2023-02-21 | William Baumgartl | Method for treating joint pain |
US20220348880A1 (en) * | 2019-08-30 | 2022-11-03 | The Texas A&M University System | Xenogen-Free Mesenchymal Stem Cell Compositions and Methods of Use |
WO2021105926A2 (en) * | 2019-11-26 | 2021-06-03 | Cells For Cells S.A. | Mesenchymal stem cells with enhanced therapeutic properties |
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IL68218A (en) * | 1983-03-23 | 1985-12-31 | Univ Ramot | Compositions for cartilage repair comprising embryonal chondrocytes |
US5053050A (en) * | 1988-04-29 | 1991-10-01 | Samuel Itay | Compositions for repair of cartilage and bone |
US5399493A (en) * | 1989-06-15 | 1995-03-21 | The Regents Of The University Of Michigan | Methods and compositions for the optimization of human hematopoietic progenitor cell cultures |
FR2667788B1 (fr) * | 1990-10-12 | 1994-12-02 | Oreal | Utilisation d'hydroxyalkylamino-9,10-anthraquinones pour la teinture de fibres keratiniques humaines, composition cosmetique les contenant en association avec des colorants azouiques et nitres. |
US5486359A (en) * | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
US5206023A (en) * | 1991-01-31 | 1993-04-27 | Robert F. Shaw | Method and compositions for the treatment and repair of defects or lesions in cartilage |
US5326357A (en) * | 1992-03-18 | 1994-07-05 | Mount Sinai Hospital Corporation | Reconstituted cartridge tissue |
US5736396A (en) * | 1995-01-24 | 1998-04-07 | Case Western Reserve University | Lineage-directed induction of human mesenchymal stem cell differentiation |
US5906934A (en) * | 1995-03-14 | 1999-05-25 | Morphogen Pharmaceuticals, Inc. | Mesenchymal stem cells for cartilage repair |
US5716616A (en) * | 1995-03-28 | 1998-02-10 | Thomas Jefferson University | Isolated stromal cells for treating diseases, disorders or conditions characterized by bone defects |
PT868505E (pt) * | 1995-11-16 | 2005-06-30 | Univ Case Western Reserve | Inducao condrogenica in vitro de celulas estaminais mesenquimais humanas |
US6482231B1 (en) * | 1995-11-20 | 2002-11-19 | Giovanni Abatangelo | Biological material for the repair of connective tissue defects comprising mesenchymal stem cells and hyaluronic acid derivative |
EP1704878B1 (de) * | 1995-12-18 | 2013-04-10 | AngioDevice International GmbH | Quervernetzte Polymerzusammensetzungen und Verfahren zu ihrer Verwendung |
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WO1999046366A1 (en) * | 1998-03-13 | 1999-09-16 | Osiris Therapeutics, Inc. | Uses for humane non-autologous mesenchymal stem cells |
IT1299488B1 (it) * | 1998-06-01 | 2000-03-16 | Afatec S R L | Tubo corrugato bimetallico e procedimento per la sua realizzazione |
BR0008787A (pt) * | 1999-02-12 | 2001-11-06 | Collagenesis Inc | Sistema à base de colágeno injetável para aplicação de células ou agentes terapêuticos |
US6716616B1 (en) * | 1999-09-28 | 2004-04-06 | Lexicon Genetics Incorporated | Human kinase proteins and polynucleotides encoding the same |
US20020005205A1 (en) * | 2000-04-25 | 2002-01-17 | Barry Francis P. | Joint repair using mesenchymal stem cells |
-
2001
- 2001-04-24 US US09/841,413 patent/US20020005205A1/en not_active Abandoned
- 2001-04-24 AU AU2001257236A patent/AU2001257236B2/en not_active Expired
- 2001-04-24 AT AT01930730T patent/ATE489101T1/de not_active IP Right Cessation
- 2001-04-24 DE DE60143517T patent/DE60143517D1/de not_active Expired - Lifetime
- 2001-04-24 EP EP01930730.5A patent/EP1276486B2/de not_active Expired - Lifetime
- 2001-04-24 ES ES01930730.5T patent/ES2353061T5/es not_active Expired - Lifetime
- 2001-04-24 CA CA2405345A patent/CA2405345C/en not_active Expired - Lifetime
- 2001-04-24 WO PCT/US2001/013267 patent/WO2001080865A2/en active Application Filing
- 2001-04-24 JP JP2001577964A patent/JP5090604B2/ja not_active Expired - Lifetime
- 2001-04-24 AU AU5723601A patent/AU5723601A/xx active Pending
- 2001-04-24 PT PT01930730T patent/PT1276486E/pt unknown
-
2008
- 2008-06-03 US US12/132,290 patent/US20090041730A1/en not_active Abandoned
-
2012
- 2012-02-22 US US13/402,444 patent/US20120148548A1/en not_active Abandoned
- 2012-06-22 JP JP2012141003A patent/JP5792686B2/ja not_active Expired - Lifetime
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2013
- 2013-01-16 US US13/743,004 patent/US9050178B2/en not_active Expired - Fee Related
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2015
- 2015-02-25 JP JP2015035361A patent/JP2015128633A/ja active Pending
- 2015-04-16 US US14/687,963 patent/US9814580B2/en not_active Expired - Fee Related
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Also Published As
Publication number | Publication date |
---|---|
EP1276486B8 (de) | 2011-01-19 |
ATE489101T1 (de) | 2010-12-15 |
JP2016216487A (ja) | 2016-12-22 |
WO2001080865A9 (en) | 2002-12-27 |
US20090041730A1 (en) | 2009-02-12 |
JP2004507454A (ja) | 2004-03-11 |
WO2001080865A3 (en) | 2002-04-11 |
AU5723601A (en) | 2001-11-07 |
EP1276486B2 (de) | 2014-03-05 |
CA2405345A1 (en) | 2001-11-01 |
EP1276486A2 (de) | 2003-01-22 |
ES2353061T5 (es) | 2014-04-07 |
US9814580B2 (en) | 2017-11-14 |
JP2012210437A (ja) | 2012-11-01 |
US20120148548A1 (en) | 2012-06-14 |
JP2015128633A (ja) | 2015-07-16 |
JP5792686B2 (ja) | 2015-10-14 |
ES2353061T3 (es) | 2011-02-25 |
US20130131804A1 (en) | 2013-05-23 |
JP5090604B2 (ja) | 2012-12-05 |
EP1276486B1 (de) | 2010-11-24 |
US9050178B2 (en) | 2015-06-09 |
WO2001080865A2 (en) | 2001-11-01 |
AU2001257236B2 (en) | 2006-03-09 |
US20020005205A1 (en) | 2002-01-17 |
JP6382262B2 (ja) | 2018-08-29 |
CA2405345C (en) | 2012-09-18 |
PT1276486E (pt) | 2011-02-07 |
US20150216904A1 (en) | 2015-08-06 |
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