UY26954A1 - Procedimiento para preparar 3-amino-2-cloro-4-metilpiridina - Google Patents

Procedimiento para preparar 3-amino-2-cloro-4-metilpiridina

Info

Publication number
UY26954A1
UY26954A1 UY26954A UY26954A UY26954A1 UY 26954 A1 UY26954 A1 UY 26954A1 UY 26954 A UY26954 A UY 26954A UY 26954 A UY26954 A UY 26954A UY 26954 A1 UY26954 A1 UY 26954A1
Authority
UY
Uruguay
Prior art keywords
amino
methylipiridine
chlorine
prepare
procedure
Prior art date
Application number
UY26954A
Other languages
English (en)
Inventor
Franklin Gupton
Original Assignee
Boheringer Ingelheim Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boheringer Ingelheim Chemicals filed Critical Boheringer Ingelheim Chemicals
Publication of UY26954A1 publication Critical patent/UY26954A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Abstract

Un método para preparar 3-amino-2-cloro-4-metilpiridina, como se muestra en el esquema 12,que sigue.
UY26954A 2000-10-10 2001-10-09 Procedimiento para preparar 3-amino-2-cloro-4-metilpiridina UY26954A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23930000P 2000-10-10 2000-10-10
US29184101P 2001-05-17 2001-05-17

Publications (1)

Publication Number Publication Date
UY26954A1 true UY26954A1 (es) 2002-06-20

Family

ID=26932446

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26954A UY26954A1 (es) 2000-10-10 2001-10-09 Procedimiento para preparar 3-amino-2-cloro-4-metilpiridina

Country Status (15)

Country Link
US (1) US6399781B1 (es)
EP (1) EP1326836B1 (es)
JP (1) JP4102665B2 (es)
AR (1) AR032369A1 (es)
AT (1) ATE266004T1 (es)
AU (1) AU2001291313A1 (es)
CA (1) CA2425494C (es)
DE (1) DE60103173T2 (es)
DK (1) DK1326836T3 (es)
ES (1) ES2220805T3 (es)
MX (1) MXPA03003177A (es)
PT (1) PT1326836E (es)
TR (1) TR200401051T4 (es)
UY (1) UY26954A1 (es)
WO (1) WO2002030901A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA200605471B (en) * 2003-12-23 2007-11-28 Dow Agrosciences Llc Process for the preparation of pyridine derivatives
US8480373B2 (en) 2004-08-26 2013-07-09 Pentair Water Pool And Spa, Inc. Filter loading
US7854597B2 (en) 2004-08-26 2010-12-21 Pentair Water Pool And Spa, Inc. Pumping system with two way communication
US7686589B2 (en) 2004-08-26 2010-03-30 Pentair Water Pool And Spa, Inc. Pumping system with power optimization
CN100358871C (zh) * 2005-08-02 2008-01-02 江阴暨阳医药化工有限公司 氰乙酰胺和丙酮合成2-氯-3-氨基-4-甲基吡啶法
CN103508945A (zh) * 2012-06-26 2014-01-15 上海品沃化工有限公司 一种2-氯-4-甲基烟腈的制备方法
CN102898361B (zh) * 2012-10-08 2014-02-19 鲁东大学 一种制备2-氯-3-氨基-4-甲基吡啶的方法
CN103664772B (zh) * 2013-11-29 2016-08-24 齐鲁工业大学 5-氯-3-氰基-4-甲氧基-2(1 h)吡啶酮的合成方法
CN104592104B (zh) * 2015-01-13 2017-02-22 江苏中邦制药有限公司 一种制备2‑氯烟酸的方法
CN105859614B (zh) * 2015-01-19 2020-05-26 盐城迪赛诺制药有限公司 一种制备2-氯-3-氰基-4-甲基吡啶的方法
WO2016118586A1 (en) * 2015-01-20 2016-07-28 Virginia Commonwealth University Lowcost, high yield synthesis of nevirapine
CN110218211B (zh) * 2018-03-01 2020-06-23 新发药业有限公司 一种奈韦拉平的简便制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3434921A1 (de) 1984-09-22 1986-05-07 Sandoz-Patent-GmbH, 7850 Lörrach Heterocyclische monoazoverbindungen
US5366972A (en) 1989-04-20 1994-11-22 Boehringer Ingelheim Pharmaceuticals, Inc. 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection
DK0551459T3 (da) 1991-06-11 1997-04-07 Boehringer Ingelheim Pharma Fremgangsmåde til fremstilling af 3-amino-2-chlor-4-alkylpyridiner
US5200522A (en) 1991-06-11 1993-04-06 Boehringer Ingelheim Pharmaceuticals, Inc. Method for preparing 3-amino-2-chloro-4-alkylpyridines
US5654429A (en) 1992-11-18 1997-08-05 Boehringer Ingelheim Pharma Method for the preparation of 3-amino-2-chloro-4-alkylpyridines
JP3516454B2 (ja) 1993-12-02 2004-04-05 ベーリンガー インゲルハイム コマンディトゲゼルシャフト ３‐アミノ‐２‐クロロ‐４‐アルキルピリジン又は‐４‐アリールピリジンの製造方法
DE4403311C1 (de) 1994-02-03 1995-04-20 Boehringer Ingelheim Kg Verfahren zur Herstellung von Nevirapine (11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4-diazepin]-6-on)
ES2218109T3 (es) 1999-01-22 2004-11-16 Boehringer Ingelheim Pharmaceuticals Inc. Sintesis de 3-amino-2-cloro-4-metilpiridina a partir de malononitrilo y acetona.
WO2000043364A1 (en) 1999-01-22 2000-07-27 Boehringer Ingelheim Pharmaceuticals, Inc. Synthesis of 3-amino-2-chloro-4-methylpyridine from acetone and ethyl cyanoacetate

Also Published As

Publication number Publication date
AR032369A1 (es) 2003-11-05
AU2001291313A1 (en) 2002-04-22
CA2425494C (en) 2008-04-29
US6399781B1 (en) 2002-06-04
JP2004529856A (ja) 2004-09-30
ATE266004T1 (de) 2004-05-15
CA2425494A1 (en) 2002-04-18
TR200401051T4 (tr) 2004-07-21
PT1326836E (pt) 2004-07-30
JP4102665B2 (ja) 2008-06-18
ES2220805T3 (es) 2004-12-16
DK1326836T3 (da) 2004-06-01
MXPA03003177A (es) 2004-12-06
EP1326836B1 (en) 2004-05-06
EP1326836A1 (en) 2003-07-16
DE60103173T2 (de) 2005-05-19
DE60103173D1 (de) 2004-06-09
US20020052507A1 (en) 2002-05-02
WO2002030901A1 (en) 2002-04-18

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20141104