DE69825976D1 - Verwendung von anti-il-12 antikörpern bei transplantationsabstossungen - Google Patents

Verwendung von anti-il-12 antikörpern bei transplantationsabstossungen

Info

Publication number
DE69825976D1
DE69825976D1 DE69825976T DE69825976T DE69825976D1 DE 69825976 D1 DE69825976 D1 DE 69825976D1 DE 69825976 T DE69825976 T DE 69825976T DE 69825976 T DE69825976 T DE 69825976T DE 69825976 D1 DE69825976 D1 DE 69825976D1
Authority
DE
Germany
Prior art keywords
antibodies
transplantation rejections
rejections
transplantation
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69825976T
Other languages
English (en)
Other versions
DE69825976T2 (de
Inventor
Terry Strom
Xian Chang Li
Martin S Zand
Xin Xiao Zheng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Beth Israel Deaconess Medical Center Inc
Original Assignee
Wyeth LLC
Beth Israel Deaconess Medical Center Inc
Beth Israel Hospital Association
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC, Beth Israel Deaconess Medical Center Inc, Beth Israel Hospital Association filed Critical Wyeth LLC
Application granted granted Critical
Publication of DE69825976D1 publication Critical patent/DE69825976D1/de
Publication of DE69825976T2 publication Critical patent/DE69825976T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE69825976T 1997-10-31 1998-10-30 Verwendung von anti-il-12 antikörpern bei transplantationsabstossungen Expired - Fee Related DE69825976T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6385397P 1997-10-31 1997-10-31
US63853P 1997-10-31
PCT/US1998/023264 WO1999022766A2 (en) 1997-10-31 1998-10-30 Use of anti-il-12 antibodies in transplantation rejection

Publications (2)

Publication Number Publication Date
DE69825976D1 true DE69825976D1 (de) 2004-10-07
DE69825976T2 DE69825976T2 (de) 2005-09-01

Family

ID=22051951

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69825976T Expired - Fee Related DE69825976T2 (de) 1997-10-31 1998-10-30 Verwendung von anti-il-12 antikörpern bei transplantationsabstossungen

Country Status (6)

Country Link
EP (1) EP0969867B1 (de)
AT (1) ATE274920T1 (de)
AU (1) AU744302B2 (de)
CA (1) CA2276420A1 (de)
DE (1) DE69825976T2 (de)
WO (1) WO1999022766A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6914128B1 (en) 1999-03-25 2005-07-05 Abbott Gmbh & Co. Kg Human antibodies that bind human IL-12 and methods for producing
US7883704B2 (en) 1999-03-25 2011-02-08 Abbott Gmbh & Co. Kg Methods for inhibiting the activity of the P40 subunit of human IL-12
NZ578065A (en) 2007-01-16 2012-09-28 Abbott Lab Methods for treating psoriasis with an antibody which binds to an epitope
BRPI0809209A2 (pt) 2007-03-29 2014-09-02 Abbott Lab Anticorpos il-12 anti-humanos cristalinos
JP2011504740A (ja) 2007-11-27 2011-02-17 アブリンクス エン．ヴェー． ヘテロ二量体サイトカイン及び／又はこれらの受容体に指向性を有するアミノ酸配列、並びにこれを含むポリペプチド
KR20100126515A (ko) 2008-03-18 2010-12-01 아보트 러보러터리즈 건선의 치료방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK122199A3 (en) * 1997-03-18 2000-12-11 Basf Ag Methods and compositions for modulating responsiveness to corticosteroids

Also Published As

Publication number Publication date
ATE274920T1 (de) 2004-09-15
EP0969867B1 (de) 2004-09-01
WO1999022766A3 (en) 1999-08-05
AU744302B2 (en) 2002-02-21
EP0969867A2 (de) 2000-01-12
CA2276420A1 (en) 1999-05-14
DE69825976T2 (de) 2005-09-01
WO1999022766A2 (en) 1999-05-14
AU1297499A (en) 1999-05-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee