AU2017321682A1 - Methods for preventing or treating allergy by administering an IL-4R antagonist - Google Patents

Methods for preventing or treating allergy by administering an IL-4R antagonist Download PDF

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Publication number
AU2017321682A1
AU2017321682A1 AU2017321682A AU2017321682A AU2017321682A1 AU 2017321682 A1 AU2017321682 A1 AU 2017321682A1 AU 2017321682 A AU2017321682 A AU 2017321682A AU 2017321682 A AU2017321682 A AU 2017321682A AU 2017321682 A1 AU2017321682 A1 AU 2017321682A1
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AU
Australia
Prior art keywords
antagonist
subject
dose
allergen
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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AU2017321682A
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English (en)
Inventor
Jennifer D. Hamilton
Brian N. SWANSON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Biotechnology SAS
Regeneron Pharmaceuticals Inc
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Sanofi Biotechnology SAS
Regeneron Pharmaceuticals Inc
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Publication date
Application filed by Sanofi Biotechnology SAS, Regeneron Pharmaceuticals Inc filed Critical Sanofi Biotechnology SAS
Publication of AU2017321682A1 publication Critical patent/AU2017321682A1/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
AU2017321682A 2016-09-01 2017-08-31 Methods for preventing or treating allergy by administering an IL-4R antagonist Pending AU2017321682A1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662382501P 2016-09-01 2016-09-01
US62/382,501 2016-09-01
US201662425726P 2016-11-23 2016-11-23
US62/425,726 2016-11-23
EP17305896.7 2017-07-10
PCT/US2017/049538 WO2018045130A1 (fr) 2016-09-01 2017-08-31 Méthodes de prévention ou de traitement de l'allergie par administration d'un antagoniste d'il-4 r

Publications (1)

Publication Number Publication Date
AU2017321682A1 true AU2017321682A1 (en) 2019-04-11

Family

ID=59923551

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017321682A Pending AU2017321682A1 (en) 2016-09-01 2017-08-31 Methods for preventing or treating allergy by administering an IL-4R antagonist

Country Status (10)

Country Link
US (2) US11771743B2 (fr)
EP (1) EP3506931A1 (fr)
JP (2) JP2019531273A (fr)
KR (2) KR102462039B1 (fr)
CN (1) CN109789196B (fr)
AU (1) AU2017321682A1 (fr)
CA (1) CA3035202A1 (fr)
MA (1) MA46098A (fr)
MX (2) MX2019002344A (fr)
WO (1) WO2018045130A1 (fr)

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KR20230111729A (ko) 2022-01-19 2023-07-26 연세대학교 원주산학협력단 단삼 추출물을 유효성분으로 포함하는 알레르기 질환 예방 또는 치료용 조성물
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CA3147113A1 (fr) 2019-08-05 2021-02-11 Regeneron Pharmaceuticals, Inc. Methodes de traitement de la dermatite atopique par administration d'un antagoniste de l'il-4r
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KR20230015965A (ko) 2020-05-22 2023-01-31 리제너론 파아마슈티컬스, 인크. Il-4r 억제제를 투여함에 의해 호산구성 식도염을 치료하기 위한 방법
US20220220211A1 (en) 2021-01-08 2022-07-14 Regeneron Pharmaceuticals, Inc. Methods for treating peanut allergy and enhancing peanut allergen-specific immunotherapy by administering an il-4r antagonist

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CN109789196A (zh) 2019-05-21
KR102462039B1 (ko) 2022-11-02
KR20220151021A (ko) 2022-11-11
CA3035202A1 (fr) 2018-03-08
US20240082353A1 (en) 2024-03-14
MX2023004306A (es) 2023-05-04
WO2018045130A1 (fr) 2018-03-08
MX2019002344A (es) 2019-09-06
EP3506931A1 (fr) 2019-07-10
KR20190042702A (ko) 2019-04-24
US20190183973A1 (en) 2019-06-20
JP2019531273A (ja) 2019-10-31
CN109789196B (zh) 2024-03-19
US11771743B2 (en) 2023-10-03
JP2022169718A (ja) 2022-11-09
MA46098A (fr) 2019-07-10

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