AU2017290354C1 - Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile - Google Patents

Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile Download PDF

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AU2017290354C1
AU2017290354C1 AU2017290354A AU2017290354A AU2017290354C1 AU 2017290354 C1 AU2017290354 C1 AU 2017290354C1 AU 2017290354 A AU2017290354 A AU 2017290354A AU 2017290354 A AU2017290354 A AU 2017290354A AU 2017290354 C1 AU2017290354 C1 AU 2017290354C1
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dosage form
oral dosage
modified release
solid oral
compound
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AU2017290354B8 (en
AU2017290354B2 (en
AU2017290354A1 (en
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Abu J. Ferdous
Wu Lin
Mohammad R. Masjedizadeh
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Principia Biopharma Inc
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Principia Biopharma Inc
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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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AU2017290354A 2016-06-29 2017-06-29 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile Active AU2017290354C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2023201685A AU2023201685A1 (en) 2016-06-29 2023-03-17 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662356345P 2016-06-29 2016-06-29
US62/356,345 2016-06-29
PCT/US2017/040075 WO2018005849A1 (en) 2016-06-29 2017-06-29 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

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AU2023201685A Division AU2023201685A1 (en) 2016-06-29 2023-03-17 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

Publications (4)

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AU2017290354A1 AU2017290354A1 (en) 2019-01-24
AU2017290354B2 AU2017290354B2 (en) 2022-12-22
AU2017290354B8 AU2017290354B8 (en) 2023-01-12
AU2017290354C1 true AU2017290354C1 (en) 2023-07-06

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AU2017290354A Active AU2017290354C1 (en) 2016-06-29 2017-06-29 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile
AU2023201685A Abandoned AU2023201685A1 (en) 2016-06-29 2023-03-17 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

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AU2023201685A Abandoned AU2023201685A1 (en) 2016-06-29 2023-03-17 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

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US (4) US20190231784A1 (cg-RX-API-DMAC7.html)
EP (1) EP3478273A1 (cg-RX-API-DMAC7.html)
JP (1) JP7129704B2 (cg-RX-API-DMAC7.html)
KR (2) KR102515813B1 (cg-RX-API-DMAC7.html)
CN (2) CN115054586B (cg-RX-API-DMAC7.html)
AU (2) AU2017290354C1 (cg-RX-API-DMAC7.html)
CA (1) CA3028169C (cg-RX-API-DMAC7.html)
EA (1) EA201892836A1 (cg-RX-API-DMAC7.html)
IL (2) IL293621B2 (cg-RX-API-DMAC7.html)
MA (1) MA45547A (cg-RX-API-DMAC7.html)
MX (2) MX390619B (cg-RX-API-DMAC7.html)
NZ (1) NZ749662A (cg-RX-API-DMAC7.html)
SG (1) SG11201811255WA (cg-RX-API-DMAC7.html)
WO (1) WO2018005849A1 (cg-RX-API-DMAC7.html)

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WO2016210165A1 (en) 2015-06-24 2016-12-29 Principia Biopharma Inc. Tyrosine kinase inhibitors
IL293621B2 (en) 2016-06-29 2023-09-01 Principia Biopharma Inc Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[4,3-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4 -Methyl-4-[4-(oxane-3-yl)piperazine-1-yl)penta-2-ananitrile
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AR119731A1 (es) 2019-05-17 2022-01-05 Novartis Ag Inhibidores del inflamasoma nlrp3
JP7784995B2 (ja) * 2019-10-09 2025-12-12 プリンシピア バイオファーマ インコーポレイテッド （ｒ）－２－［３－［４－アミノ－３－（２－フルオロ－４－フェノキシ－フェニル）ピラゾロ［３，４－ｄ］ピリミジン－１－イル］ピペリジン－１－カルボニル］－４－メチル－４－［４－（オキセタン－３－イル）ピペラジン－１－イル］ペンタ－２－エンニトリルを投与することによる天疱瘡を処置する方法
US20210106584A1 (en) 2019-10-14 2021-04-15 Principia Biopharma Inc. Methods for treating immune thrombocytopenia by administering (r)-2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile
CA3163278A1 (en) * 2020-01-06 2021-07-15 Philip Nunn Treatment of membranous nephropathy, igg4-related disease, and antiphospholipid syndrome using btk inhibitor 2-[(3r)-3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitril
MX2022008428A (es) 2020-01-08 2022-08-08 Principia Biopharma Inc Composiciones farmaceuticas topicas que comprenden 2-[3-[4-amino-3-(2-fluoro-4-fenoxi-fenil)-1h-pirazolo[3,4-d]pirim idin-1-il]piperidina-1-carbonil]-4,4-dimetilpent-2-enonitrilo.
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KR20220054906A (ko) 2022-05-03
US20190231784A1 (en) 2019-08-01
KR20190025947A (ko) 2019-03-12
AU2017290354B2 (en) 2022-12-22
US20250381193A1 (en) 2025-12-18
IL293621B1 (en) 2023-05-01
EA201892836A1 (ru) 2019-07-31
JP7129704B2 (ja) 2022-09-02
MX2022002952A (es) 2022-04-06
CN109600989A (zh) 2019-04-09
MX390619B (es) 2025-03-21
MA45547A (fr) 2019-05-08
CN115054586B (zh) 2024-08-02
AU2017290354A1 (en) 2019-01-24
KR102391693B1 (ko) 2022-04-29
WO2018005849A1 (en) 2018-01-04
CA3028169A1 (en) 2018-01-04
US20240207275A1 (en) 2024-06-27
EP3478273A1 (en) 2019-05-08
BR112018077503A2 (pt) 2019-04-09

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