AU2011342368B2 - Gastric and colonic formulations and methods for making and using them - Google Patents

Gastric and colonic formulations and methods for making and using them Download PDF

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Publication number
AU2011342368B2
AU2011342368B2 AU2011342368A AU2011342368A AU2011342368B2 AU 2011342368 B2 AU2011342368 B2 AU 2011342368B2 AU 2011342368 A AU2011342368 A AU 2011342368A AU 2011342368 A AU2011342368 A AU 2011342368A AU 2011342368 B2 AU2011342368 B2 AU 2011342368B2
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Australia
Prior art keywords
salt
composition
bisoxatin
sodium
capsules
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Ceased
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AU2011342368A
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AU2011342368A1 (en
Inventor
Thomas Julius Borody
Sanjay Ramrakha
John Saxon
Antony Wettstein
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Rite Prep Pty Ltd
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Rite Prep Pty Ltd
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Publication of AU2011342368A1 publication Critical patent/AU2011342368A1/en
Assigned to SALIX PHARMACEUTICALS, INC. reassignment SALIX PHARMACEUTICALS, INC. Request for Assignment Assignors: BORODY, THOMAS, RAMRAKHA, SANJAY, SAXON, JOHN, WETTSTEIN, ANTONY
Application granted granted Critical
Publication of AU2011342368B2 publication Critical patent/AU2011342368B2/en
Assigned to Rite-Prep Pty Ltd reassignment Rite-Prep Pty Ltd Request for Assignment Assignors: SALIX PHARMACEUTICALS, INC.
Ceased legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Nutrition Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2011342368A 2010-12-13 2011-12-13 Gastric and colonic formulations and methods for making and using them Ceased AU2011342368B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42256710P 2010-12-13 2010-12-13
USUS61/422,567 2010-12-13
PCT/AU2011/001609 WO2012079118A1 (en) 2010-12-13 2011-12-13 Gastric and colonic formulations and methods for making and using them

Publications (2)

Publication Number Publication Date
AU2011342368A1 AU2011342368A1 (en) 2013-05-09
AU2011342368B2 true AU2011342368B2 (en) 2016-11-17

Family

ID=46243884

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2011342368A Ceased AU2011342368B2 (en) 2010-12-13 2011-12-13 Gastric and colonic formulations and methods for making and using them

Country Status (15)

Country Link
US (2) US10092573B2 (enExample)
EP (1) EP2651415B1 (enExample)
JP (1) JP6121334B2 (enExample)
KR (1) KR101947720B1 (enExample)
CN (2) CN110200954A (enExample)
AU (1) AU2011342368B2 (enExample)
BR (1) BR112013014827A2 (enExample)
CA (1) CA2821196C (enExample)
DK (1) DK2651415T3 (enExample)
IL (1) IL226831B (enExample)
MX (1) MX355760B (enExample)
NZ (1) NZ611868A (enExample)
PL (1) PL2651415T3 (enExample)
SG (1) SG191145A1 (enExample)
WO (1) WO2012079118A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPS088702A0 (en) * 2002-03-04 2002-03-28 Borody, Thomas Julius Electrolyte purgative
AU2011342368B2 (en) 2010-12-13 2016-11-17 Rite-Prep Pty Ltd Gastric and colonic formulations and methods for making and using them
IN2014DN03373A (enExample) * 2011-10-27 2015-06-05 Borody Thomas J
US10166219B2 (en) * 2012-07-27 2019-01-01 Redhill Bipharma Ltd. Formulations and methods of manufacturing formulations for use in colonic evacuation
JP2015531770A (ja) * 2012-08-29 2015-11-05 サリックス ファーマシューティカルズ，インコーポレイテッド 緩下剤組成物、ならびに便秘および関連胃腸疾患および症状を処置するための方法
JP6441890B2 (ja) 2013-03-15 2018-12-19 ブレインツリー・ラボラトリーズ，インコーポレイテッド 硫酸塩の両用経口薬学的組成物錠剤およびその使用の方法
JP6394142B2 (ja) * 2013-07-25 2018-09-26 大正製薬株式会社 固形製剤
KR101423005B1 (ko) * 2013-10-17 2014-07-28 강윤식 장 세정용 조성물
WO2015056897A1 (ko) * 2013-10-17 2015-04-23 강윤식 장 세정용 조성물
CN103550212A (zh) * 2013-11-03 2014-02-05 王显著 含匹可硫酸和抗坏血酸的药物组合物
WO2016071756A1 (en) * 2014-11-04 2016-05-12 Innopharmax, Inc. Oral administration of unstable or poorly-absorbed drugs
GB201511255D0 (en) * 2015-06-26 2015-08-12 Colltec Ltd Formulation
JP6460552B2 (ja) * 2015-07-14 2019-01-30 国立大学法人大阪大学 筋強直性ジストロフィー治療薬
CN106910184B (zh) * 2017-01-12 2020-10-09 杭州电子科技大学 基于深度卷积神经网络的内窥镜图像肠道出血检测方法
US10143656B1 (en) * 2017-08-04 2018-12-04 Braintree Laboratories, Inc. Solid oral sulfate salt formulations for cleaning a colon and methods of using same
KR102868782B1 (ko) 2018-01-12 2025-10-13 (주)메티메디제약 만성 염증성 질환의 치료 방법
KR102111094B1 (ko) 2018-06-18 2020-05-14 주식회사 한국팜비오 무수황산나트륨, 황산칼륨, 무수황산마그네슘 및 시메티콘을 포함하는 장관하제 경구투여용 고형제제 조성물
CN108904808A (zh) * 2018-08-15 2018-11-30 西安力邦医药科技有限责任公司 一种治疗便秘的药物组合物及其应用
CN109289095B (zh) * 2018-11-23 2021-03-26 淮海工学院 一种含盐酸利多卡因的肠镜凝胶剂及其制备方法
WO2020165658A2 (en) * 2019-02-15 2020-08-20 Seaford Pharmaceuticals Inc. Method to prevent complications associated with bowel cleansing and dosing kit
US11554155B2 (en) 2020-01-20 2023-01-17 Advanced Health Solutions LLC Compositions and methods for improving gastrointestinal function
EP4093259A4 (en) * 2020-01-20 2024-04-10 Advanced Health Solutions LLC COMPOSITIONS AND METHODS FOR IMPROVING VISIBILITY OF THE GASTROINTESTINAL TRACT DURING ENDOSCOPY PROCEDURES
CN111494313A (zh) * 2020-05-25 2020-08-07 李会芳 一种用于母猪便秘治疗的灌肠液及其制备方法
US20230320562A1 (en) * 2020-09-08 2023-10-12 Given Imaging Ltd. Estimating the adequacy of a procedure
KR20230124560A (ko) * 2020-10-26 2023-08-25 브레인트리 라보라토리이즈, 인코포레이티드 결장 세정을 위한 술페이트 염 제제
CN112587498A (zh) * 2020-12-29 2021-04-02 哈尔滨瀚钧现代制药有限公司 多库酯钠丹蒽醌及其制备方法
JP2024501839A (ja) * 2020-12-31 2024-01-16 テジュン ファーマシューティカル カンパニー リミテッド 腸管洗浄用の経口固形製剤
WO2025006623A2 (en) * 2023-06-26 2025-01-02 Reflux Gourmet Llc Functional gum comprising an alginate blend

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020071872A1 (en) * 1999-09-07 2002-06-13 Mcnally Gerard P. Laxative composition
WO2005051361A1 (en) * 2003-11-19 2005-06-09 Inkine Pharmaceutical Company, Inc. Colonic purgative composition with soluble binding agent
WO2006118370A1 (en) * 2005-04-29 2006-11-09 Amorepacific Corporation Composition for improving constipation comprising sugar and sugar alcohols

Family Cites Families (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA761927A (en) * 1967-06-27 Seeger Ernst Benzoxazine derivatives
US4186025A (en) 1975-09-25 1980-01-29 Merck & Co., Inc. Aqueous polysaccharide composition
US4452779A (en) 1982-02-03 1984-06-05 Cockerill Vernon Composition and method of treating lactating mammals
JPS58222020A (ja) * 1982-06-18 1983-12-23 Teijin Ltd 前処置用下剤
DK454683D0 (da) 1983-10-03 1983-10-03 Mogens Gjerloev Tarmreguleringsmiddel til behandling af diarre hos dyr samt anvendelse heraf
EP0222834A4 (en) 1985-04-18 1989-10-04 Borody Thomas J TREATMENT OF NON-ULCERATIVE DYSPEPSIA WITH BISMUTOUS SALTS.
US4766004A (en) 1986-12-19 1988-08-23 Warner-Lambert Company Crunchy, highly palatable, bulk-increasing, dietary fiber supplement composition
IL86859A (en) 1987-07-10 1991-12-15 E Z Em Inc Aqueous cathartic solution containing inorganic salts
EP0439453B1 (en) 1987-10-12 1994-01-19 Exomed Australia Pty. Ltd. (ACN 051 976 446) Improved method for treatment of gastrointestinal disorders
DE3889547T2 (de) 1987-12-24 1994-11-17 Borody Thomas J Orthostatische waschlösungen.
WO1990001335A1 (en) 1988-08-02 1990-02-22 Borody Thomas J Treatment of gastro-intestinal disorders
US5443826A (en) 1988-08-02 1995-08-22 Borody; Thomas J. Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli
US5213807A (en) 1990-05-03 1993-05-25 Chemburkar Pramod B Pharmaceutical composition containing ibuprofen and a prostaglandin
US5232699A (en) 1990-07-26 1993-08-03 The Proctor & Gamble Company Laxative compositions
WO1992006690A1 (en) 1990-10-22 1992-04-30 Borody Thomas J Treatment of non-inflammatory and non-infectious bowel disorders
US5519014A (en) 1990-10-22 1996-05-21 Borody; Thomas J. Treatment of non-inflammatory and non-infectious bowel disorders
US5173296A (en) 1990-11-16 1992-12-22 The Procter & Gamble Company Compositions containing psyllium
JP3047143B2 (ja) 1992-04-24 2000-05-29 堀井薬品工業株式会社 腸管洗浄液用組成物及び腸管洗浄液
WO1995011024A1 (en) 1993-10-19 1995-04-27 The Procter & Gamble Company Picosulphate dosage form
JP3850891B2 (ja) 1994-03-01 2006-11-29 ゼリア新薬工業株式会社 緩下効果を有する組成物
AUPM695294A0 (en) 1994-07-20 1994-08-11 Borody, Thomas Julius Improved combination therapy dose unit
AUPM864894A0 (en) 1994-10-07 1994-11-03 Borody, Thomas Julius Treatment of bowel-dependent neurological disorders
JP3010007B2 (ja) 1995-05-22 2000-02-14 ビオフェルミン製薬株式会社 配合下剤
RU2098100C1 (ru) 1995-10-11 1997-12-10 Максимова Ирина Сергеевна Ирригационный раствор для офтальмологических операций
AU771576B2 (en) 1995-11-03 2004-03-25 Red Hill Biopharma Ltd. Improved preparation for colonic evacuation
AUPN634595A0 (en) 1995-11-03 1995-11-30 Borody, Thomas Julius Improved method for colonic evacuation
US6103268A (en) 1995-11-03 2000-08-15 Borody; Thomas Julius Administering osmotic colonic evacuant containing a picosulfate
NZ333493A (en) 1995-11-03 2000-06-23 Nicolas Peter Shortis Method of evacuating a patient's colon by oral administration of an osmotic colonic evacuant in powder form
JP3423842B2 (ja) 1996-01-19 2003-07-07 日研化学株式会社 変異株及び該変異株又は親株を用いるエリスリトールの製造方法
US6087386A (en) 1996-06-24 2000-07-11 Merck & Co., Inc. Composition of enalapril and losartan
EP0845538B1 (en) 1996-12-02 2003-04-02 Mitsubishi Chemical Corporation Method of producing erythritol
US5948787A (en) 1997-02-28 1999-09-07 Alza Corporation Compositions containing opiate analgesics
KR19980075195A (ko) 1997-03-26 1998-11-16 손경식 트리코스포로노이데스 속 변이균주 및 이를 이용한 에리스리톨의 제조방법
US6162464A (en) 1997-03-31 2000-12-19 Inkine Pharmaceutical, Inc. Non-aqueous colonic purgative formulations
US6551632B2 (en) 1997-04-01 2003-04-22 Thomas Julius Borody Methods and compositions for treating inflammatory bowel disease
DE69839261T2 (de) 1997-04-01 2009-03-26 Borody, Thomas Julius, Five Dock Verfahren und zusammensetzungen zur behandlung entzündlicher darmerkrankungen
EP0988858A1 (en) * 1997-04-18 2000-03-29 Taisho Pharmaceutical Co., Ltd Microemulsion
AUPO665397A0 (en) 1997-05-07 1997-05-29 Borody, Thomas Julius Novel therapy for constipation
JP4092748B2 (ja) 1997-09-05 2008-05-28 ニプロ株式会社 腸管洗浄液
KR100541578B1 (ko) 1997-12-04 2006-04-06 미쓰비시 가가꾸 가부시키가이샤 에리트리톨 생산방법
NZ505123A (en) 1997-12-19 2003-07-25 Smithkline Beecham Corp Process for manufacturing bite-dispersion tablets by compressing medicaments and other ingredients into granulates then compressing the granulates and other ingredients into tablets, and the tablets thereof
AUPP325398A0 (en) 1998-04-30 1998-05-21 Borody, Thomas J. Improved method for eradicating h. pylori
AUPP437698A0 (en) 1998-06-30 1998-07-23 Baumgart, Karl Methods for treatment of coronary, carotid and other vascular disease
US6001616A (en) 1998-09-16 1999-12-14 Dong Cheon Consulting Co., Ltd. Process for preparing erythritol using novel cell of pichia
EP1005863A1 (en) 1998-12-04 2000-06-07 Synthelabo Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof
US6245740B1 (en) 1998-12-23 2001-06-12 Amgen Inc. Polyol:oil suspensions for the sustained release of proteins
DE60040214D1 (de) 1999-02-26 2008-10-23 Shionogi & Co Kaubare weichkapseln mit verbesserten verabreichungseigenschaften sowie verfahren zu deren herstellung
US6858403B2 (en) 1999-05-11 2005-02-22 M-Biotech, Inc. Polymer matrix containing catalase co-immobilized with analytic enzyme that generates hydrogen peroxide
DE19930030B4 (de) 1999-06-30 2004-02-19 Meduna Arzneimittel Gmbh CO-3-ungesättigte Fettsäuren enthaltende orale Darreichungsform
JP2001114668A (ja) * 1999-10-13 2001-04-24 Meiji Seika Kaisha Ltd チョコレート剤
US6774111B1 (en) 2000-03-14 2004-08-10 Abbott Laboratories Carbohydrate system and a method for providing nutrition to a diabetic
NZ522036A (en) 2000-04-19 2004-04-30 Borody Thomas J Compositions and therapies for hyperlipidaemia-associated disorders
JP2003535903A (ja) 2000-06-19 2003-12-02 ミューコプロテック・プロプライエタリー・リミテッド プロバイオティックを用いた、粘膜表面での細菌またはウイルス感染の免疫療法または治療、およびそのための組成物
AUPQ854100A0 (en) 2000-07-03 2000-07-27 Helirad Pty Ltd Methods for monitoring treatment of helicobacter infection
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
EP1367907B1 (en) 2001-03-13 2007-02-28 Kellogg Company Aerated food component
US6790453B2 (en) 2001-03-14 2004-09-14 Mccormick & Company, Inc. Encapsulation compositions and process for preparing the same
US7815956B2 (en) 2001-04-27 2010-10-19 Pepsico Use of erythritol and D-tagatose in diet or reduced-calorie beverages and food products
IL159129A0 (en) 2001-06-01 2004-05-12 Pozen Inc PHARMACEUTICAL COMPOSITIONS FOR THE COORDINATED DELIVERY OF NSAIDs
AU2002315779B2 (en) 2001-07-05 2007-03-22 Wakunaga Pharmaceutical Co.,Ltd Soft capsules
US20030092724A1 (en) 2001-09-18 2003-05-15 Huaihung Kao Combination sustained release-immediate release oral dosage forms with an opioid analgesic and a non-opioid analgesic
AUPS017702A0 (en) 2002-01-25 2002-02-14 Atopic Pty Ltd Methods and compositions for the treatment of asthma and related disorders
AUPS088702A0 (en) 2002-03-04 2002-03-28 Borody, Thomas Julius Electrolyte purgative
US6753009B2 (en) 2002-03-13 2004-06-22 Mcneil-Ppc, Inc. Soft tablet containing high molecular weight polyethylene oxide
ES2320748T5 (es) 2002-04-05 2017-02-20 Euro-Celtique S.A. Matriz para la liberación sostenida, invariable e independiente de compuestos activos
US6946149B2 (en) 2002-04-30 2005-09-20 Braintree Laboratories, Inc. Salt solution for colon cleansing
AU2003900553A0 (en) 2003-02-10 2003-02-20 Borody, Thomas Julius Novel Improved Method for Detection of Dientamoeba fragilis and other Parasites
JP4458761B2 (ja) * 2003-03-27 2010-04-28 ロート製薬株式会社 瀉下用製剤
RU2005134364A (ru) * 2003-04-08 2006-06-10 Проджиникс Фармасьютикалз, Инк. (Us) Комбинированное лечение запора
AU2004238321B2 (en) * 2003-05-07 2009-08-27 Samyang Biopharmaceuticals Corporation Highly plastic granules for making fast melting tablets
CA2559239C (en) * 2004-04-13 2021-04-06 Boehringer Ingelheim International Gmbh Use of simethicone and sodium picosulphate in constipated patients suffering from bloated feeling and gas discomfort during the night
PT1750702E (pt) * 2004-06-04 2010-11-11 Braintree Lab Método de lavagem intestinal
US20060275223A1 (en) 2005-06-02 2006-12-07 Burr James B Erythritol compositions for teeth and gums
WO2007057924A1 (en) 2005-11-21 2007-05-24 Panacea Biotec Ltd Laxative composition on the basis of triphala
CA2635313C (en) 2005-12-29 2013-12-31 Osmotica Corp. Triple combination release multi-layered tablet
US20070185145A1 (en) 2006-02-03 2007-08-09 Royds Robert B Pharmaceutical composition containing a central opioid agonist, a central opioid antagonist, and a peripheral opioid antagonist, and method for making the same
CN101033010A (zh) * 2006-03-09 2007-09-12 麦迪森企业股份有限公司 塑料容器的内容物封装方法及其容器的制造流程
JP5006567B2 (ja) 2006-04-14 2012-08-22 花王株式会社 口腔用固形製剤
WO2008021394A2 (en) * 2006-08-15 2008-02-21 Theraquest Biosciences, Llc Pharmaceutical formulations of cannabinoids and method of use
WO2008027442A2 (en) 2006-08-30 2008-03-06 Theraquest Biosciences, Llc Abuse deterrent oral pharmaceutical formulations of opioid agonists and method of use
JP2008115085A (ja) * 2006-11-01 2008-05-22 Tendou Seiyaku Kk 緩下剤
AU2008253583A1 (en) * 2007-05-17 2008-11-27 David Lubowski Combination laxative compositions comprising a colonic stimulant and a bulking laxative
CA2687192C (en) 2007-06-04 2015-11-24 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
JP2010529073A (ja) 2007-06-06 2010-08-26 ビーエーエスエフ ソシエタス・ヨーロピア チュアブル錠及びトローチ剤製造のための医薬製剤
WO2008148742A2 (de) 2007-06-06 2008-12-11 Basf Se Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten
DK2264042T3 (da) 2007-07-27 2012-08-20 Cargill Inc Mikronisering af polyoler
US20100233278A1 (en) 2007-09-27 2010-09-16 Akiko Ookawa Rapidly disintegrating solid preparation
PL2572705T3 (pl) 2007-10-01 2018-01-31 Lesvi Laboratorios Sl Tabletki ulegające rozpadowi w jamie ustnej
MX2010004222A (es) 2007-10-19 2010-09-14 Purdue Research Foundation Formulaciones solidas de compuestos cristalinos.
JP5258268B2 (ja) 2007-11-19 2013-08-07 フロイント産業株式会社 球形粒の製造方法
US20090155363A1 (en) 2007-12-14 2009-06-18 Todd Maibach Methods for oral administration of active drugs
WO2009084678A1 (ja) 2007-12-28 2009-07-09 Sawai Pharmaceutical Co., Ltd. 口腔内崩壊錠およびその製造方法
US20090258090A1 (en) 2008-04-11 2009-10-15 Braintree Laboratories, Inc. Colon cleansing solution
US20100178413A1 (en) 2008-12-17 2010-07-15 Mark Gorris Food-based Supplement Delivery System
US20100285164A1 (en) 2009-05-11 2010-11-11 Jrs Pharma Orally Disintegrating Excipient
WO2010138439A1 (en) 2009-05-28 2010-12-02 Aptapharma, Inc. Multiparticulate controlled-release selective serotonin reuptake inhibitor formulations
US20110218216A1 (en) 2010-01-29 2011-09-08 Kumaravel Vivek Extended release pharmaceutical composition of donepezil
AU2011342368B2 (en) 2010-12-13 2016-11-17 Rite-Prep Pty Ltd Gastric and colonic formulations and methods for making and using them
IN2014DN03373A (enExample) 2011-10-27 2015-06-05 Borody Thomas J
US10166219B2 (en) 2012-07-27 2019-01-01 Redhill Bipharma Ltd. Formulations and methods of manufacturing formulations for use in colonic evacuation
JP2015531770A (ja) 2012-08-29 2015-11-05 サリックス ファーマシューティカルズ，インコーポレイテッド 緩下剤組成物、ならびに便秘および関連胃腸疾患および症状を処置するための方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020071872A1 (en) * 1999-09-07 2002-06-13 Mcnally Gerard P. Laxative composition
WO2005051361A1 (en) * 2003-11-19 2005-06-09 Inkine Pharmaceutical Company, Inc. Colonic purgative composition with soluble binding agent
WO2006118370A1 (en) * 2005-04-29 2006-11-09 Amorepacific Corporation Composition for improving constipation comprising sugar and sugar alcohols

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