AU2007333243B2 - Phosphoinositide 3-kinase inhibitor compounds and methods of use - Google Patents

Phosphoinositide 3-kinase inhibitor compounds and methods of use Download PDF

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Publication number
AU2007333243B2
AU2007333243B2 AU2007333243A AU2007333243A AU2007333243B2 AU 2007333243 B2 AU2007333243 B2 AU 2007333243B2 AU 2007333243 A AU2007333243 A AU 2007333243A AU 2007333243 A AU2007333243 A AU 2007333243A AU 2007333243 B2 AU2007333243 B2 AU 2007333243B2
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AU
Australia
Prior art keywords
pyrimidin
morpholinothieno
methyl
aminopyrimidin
amine
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Ceased
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AU2007333243A
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English (en)
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AU2007333243A1 (en
Inventor
Tracy Bayliss
Georgette Castanedo
Irina Chuckowree
Jennafer Dotson
Adrian Folkes
Richard Goldsmith
Janet Gunzner
Tim Heffron
Simon Mathieu
Alan Olivero
Steven Staben
Daniel P. Sutherlin
Vickie Tsui
Nan Chi Wan
Shumei Wang
Bing-Yan Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Genentech Inc
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F Hoffmann La Roche AG
Genentech Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39403189&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2007333243(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F Hoffmann La Roche AG, Genentech Inc filed Critical F Hoffmann La Roche AG
Publication of AU2007333243A1 publication Critical patent/AU2007333243A1/en
Assigned to GENENTECH, INC., F. HOFFMANN-LA ROCHE AG reassignment GENENTECH, INC. Alteration of Name(s) of Applicant(s) under S113 Assignors: BAYLISS, TRACY, CASTANEDO, GEORGETTE, CHUCKOWREE, IRINA, DOTSON, JENNAFER, FOLKES, ADRIAN, GENENTECH, INC., GOLDSMITH, RICHARD, GUNZNER, JANET, HEFFRON, TIM, MATHIEU, SIMON, OLIVERO, ALAN, PIRAMED LIMITED, STABEN, STEVEN, SUTHERLIN, DANIEL P., TSUI, VICKIE, WAN, NAN CHI, ZHU, BING-YAN
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Publication of AU2007333243B2 publication Critical patent/AU2007333243B2/en
Ceased legal-status Critical Current
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
AU2007333243A 2006-12-07 2007-12-05 Phosphoinositide 3-kinase inhibitor compounds and methods of use Ceased AU2007333243B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87342206P 2006-12-07 2006-12-07
US60/873,422 2006-12-07
PCT/US2007/086533 WO2008073785A2 (en) 2006-12-07 2007-12-05 Phosphoinositide 3-kinase inhibitor compounds and methods of use

Publications (2)

Publication Number Publication Date
AU2007333243A1 AU2007333243A1 (en) 2008-06-19
AU2007333243B2 true AU2007333243B2 (en) 2013-03-14

Family

ID=39403189

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007333243A Ceased AU2007333243B2 (en) 2006-12-07 2007-12-05 Phosphoinositide 3-kinase inhibitor compounds and methods of use

Country Status (19)

Country Link
US (1) US9487533B2 (en:Method)
EP (1) EP2114950B1 (en:Method)
JP (1) JP5500990B2 (en:Method)
KR (1) KR101507182B1 (en:Method)
CN (1) CN101675053B (en:Method)
AR (1) AR064154A1 (en:Method)
AU (1) AU2007333243B2 (en:Method)
BR (1) BRPI0717907A2 (en:Method)
CA (1) CA2671845C (en:Method)
CL (1) CL2007003523A1 (en:Method)
ES (1) ES2571028T3 (en:Method)
IL (1) IL199151A (en:Method)
MX (1) MX2009005925A (en:Method)
NO (1) NO342697B1 (en:Method)
PE (1) PE20081353A1 (en:Method)
RU (1) RU2470936C2 (en:Method)
TW (1) TW200829594A (en:Method)
WO (1) WO2008073785A2 (en:Method)
ZA (1) ZA200904531B (en:Method)

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