AU2004242928B2 - Triheterocyclic compounds, compositions, and methods for treating cancer or viral diseases - Google Patents

Triheterocyclic compounds, compositions, and methods for treating cancer or viral diseases Download PDF

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Publication number
AU2004242928B2
AU2004242928B2 AU2004242928A AU2004242928A AU2004242928B2 AU 2004242928 B2 AU2004242928 B2 AU 2004242928B2 AU 2004242928 A AU2004242928 A AU 2004242928A AU 2004242928 A AU2004242928 A AU 2004242928A AU 2004242928 B2 AU2004242928 B2 AU 2004242928B2
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AU
Australia
Prior art keywords
nhr
alkyl
nhc
compound
phenyl
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Ceased
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AU2004242928A
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AU2004242928A1 (en
Inventor
Giorgio Attardo
Xavier Billot
Kenza Dairi
Terrence W Doyle
Jean-Francois Lavallee
Elise Rioux
Sasmita Tripathy
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Gemin X Pharmaceuticals Canada Inc
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Gemin X Pharmaceuticals Canada Inc
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Assigned to GEMIN X PHARMACEUTICALS CANADA INC. reassignment GEMIN X PHARMACEUTICALS CANADA INC. Alteration of Name(s) of Applicant(s) under S113 Assignors: GEMIN X BIOTECHNOLOGIES INC.
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
AU2004242928A 2003-05-30 2004-05-28 Triheterocyclic compounds, compositions, and methods for treating cancer or viral diseases Ceased AU2004242928B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47474103P 2003-05-30 2003-05-30
US60/474,741 2003-05-30
PCT/CA2004/000793 WO2004106328A1 (en) 2003-05-30 2004-05-28 Triheterocyclic compounds, compositions, and methods for treating cancer or viral diseases

Publications (2)

Publication Number Publication Date
AU2004242928A1 AU2004242928A1 (en) 2004-12-09
AU2004242928B2 true AU2004242928B2 (en) 2011-03-10

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AU2004242928A Ceased AU2004242928B2 (en) 2003-05-30 2004-05-28 Triheterocyclic compounds, compositions, and methods for treating cancer or viral diseases

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US (4) US7425553B2 (OSRAM)
EP (1) EP1644363B1 (OSRAM)
JP (1) JP4980715B2 (OSRAM)
KR (1) KR101168441B1 (OSRAM)
CN (1) CN1832939B (OSRAM)
AT (1) ATE546456T1 (OSRAM)
AU (1) AU2004242928B2 (OSRAM)
BR (1) BRPI0410870A (OSRAM)
CA (1) CA2527583C (OSRAM)
CY (1) CY1113038T1 (OSRAM)
DK (1) DK1644363T3 (OSRAM)
ES (1) ES2382377T3 (OSRAM)
HR (1) HRP20120379T1 (OSRAM)
IL (1) IL172189A (OSRAM)
MX (1) MXPA05012799A (OSRAM)
NO (1) NO333006B1 (OSRAM)
NZ (1) NZ543897A (OSRAM)
PL (1) PL1644363T3 (OSRAM)
PT (1) PT1644363E (OSRAM)
RU (1) RU2360913C2 (OSRAM)
SI (1) SI1644363T1 (OSRAM)
WO (1) WO2004106328A1 (OSRAM)
ZA (1) ZA200509718B (OSRAM)

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