AU2002365141C1 - Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends - Google Patents
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends Download PDFInfo
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- AU2002365141C1 AU2002365141C1 AU2002365141A AU2002365141A AU2002365141C1 AU 2002365141 C1 AU2002365141 C1 AU 2002365141C1 AU 2002365141 A AU2002365141 A AU 2002365141A AU 2002365141 A AU2002365141 A AU 2002365141A AU 2002365141 C1 AU2002365141 C1 AU 2002365141C1
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- immunomer
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- nucleoside
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- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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- C07K—PEPTIDES
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- C12N2310/18—Type of nucleic acid acting by a non-sequence specific mechanism
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- C12N2310/3183—Diol linkers, e.g. glycols or propanediols
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34476701P | 2001-10-24 | 2001-10-24 | |
| US60/344,767 | 2001-10-24 | ||
| PCT/US2002/034247 WO2003057822A2 (en) | 2001-10-24 | 2002-10-24 | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends |
Publications (3)
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| AU2002365141A1 AU2002365141A1 (en) | 2003-07-24 |
| AU2002365141B2 AU2002365141B2 (en) | 2007-06-14 |
| AU2002365141C1 true AU2002365141C1 (en) | 2008-07-24 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002365141A Expired AU2002365141C1 (en) | 2001-10-24 | 2002-10-24 | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends |
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| KR (1) | KR100945104B1 (enExample) |
| AU (1) | AU2002365141C1 (enExample) |
| CA (1) | CA2463798C (enExample) |
| WO (2) | WO2003035836A2 (enExample) |
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| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| AU2002345847B2 (en) | 2001-06-21 | 2008-05-29 | Dynavax Technologies Corporation | Chimeric immunomodulatory compounds and methods of using the same |
| US7276489B2 (en) * | 2002-10-24 | 2007-10-02 | Idera Pharmaceuticals, Inc. | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends |
| EP1393745A1 (en) * | 2002-07-29 | 2004-03-03 | Hybridon, Inc. | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5'ends |
| AR040996A1 (es) | 2002-08-19 | 2005-04-27 | Coley Pharm Group Inc | Acidos nucleicos inmunoestimuladores |
| DE60335477D1 (de) | 2002-10-11 | 2011-02-03 | Novartis Vaccines & Diagnostic | Polypeptidimpstoffe zum breiten schutz gegen hypervirulente meningokokken-linien |
| MXPA05004588A (es) | 2002-10-29 | 2005-12-14 | Coley Pharmaceutical Group Ltd | Metodos y productos relacionados con el tratamiento y prevencion de infeccion de virus de hepatitis c. |
| WO2004053104A2 (en) | 2002-12-11 | 2004-06-24 | Coley Pharmaceutical Group, Inc. | 5’ cpg nucleic acids and methods of use |
| JP2006516099A (ja) * | 2002-12-23 | 2006-06-22 | ダイナバックス テクノロジーズ コーポレイション | 分枝状の免疫調節化合物及び該化合物の使用方法 |
| PT2172213E (pt) | 2003-01-30 | 2013-06-03 | Novartis Ag | Vacinas injetáveis contra múltiplos serogrupos meningocócicos |
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| NZ543467A (en) | 2003-04-10 | 2008-07-31 | Novartis Vaccines & Diagnostic | The severe acute respiratory syndrome coronavirus |
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| KR101126030B1 (ko) * | 2003-07-15 | 2012-03-19 | 이데라 파마슈티칼즈, 인코포레이티드 | 사이토킨 및/또는 화학치료제 또는 방사선 치료와 연계하여면역자극 올리고누클레오티드 및/또는 이뮤노머 화합물을이용하여 면역계를 공동 상승 자극시키는 방법 |
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| JP2008501807A (ja) * | 2004-06-08 | 2008-01-24 | コーリー ファーマシューティカル ゲーエムベーハー | 抗原ならびに免疫活性化アゴニストおよび免疫活性化アンタゴニストのための担体基本骨格としての無塩基オリゴヌクレオチド |
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| US6172208B1 (en) * | 1992-07-06 | 2001-01-09 | Genzyme Corporation | Oligonucleotides modified with conjugate groups |
| JP2000506384A (ja) * | 1996-02-15 | 2000-05-30 | ナショナル インスティチューツ オブ ヘルス | RNase L アクチベーター及びRSV感染の治療に有効なアンチセンスオリゴヌクレオチド |
| US5856462A (en) * | 1996-09-10 | 1999-01-05 | Hybridon Incorporated | Oligonucleotides having modified CpG dinucleosides |
| ES2284247T3 (es) * | 1998-04-03 | 2007-11-01 | University Of Iowa Research Foundation | Metodos y productos para estimular el sistema inmunitario usando oligonucleotidos y citoquinas inmunoterapeuticos. |
| AU9475001A (en) * | 2000-09-26 | 2002-04-08 | Hybridon Inc | Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes |
| AU2002345847B2 (en) * | 2001-06-21 | 2008-05-29 | Dynavax Technologies Corporation | Chimeric immunomodulatory compounds and methods of using the same |
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- 2002-10-24 AU AU2002365141A patent/AU2002365141C1/en not_active Expired
- 2002-10-24 KR KR1020047006160A patent/KR100945104B1/ko not_active Expired - Lifetime
- 2002-10-24 CA CA2463798A patent/CA2463798C/en not_active Expired - Lifetime
- 2002-10-24 JP JP2003558124A patent/JP5005878B2/ja not_active Expired - Lifetime
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| WO2003057822A2 (en) | 2003-07-17 |
| KR100945104B1 (ko) | 2010-03-02 |
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| WO2003035836A2 (en) | 2003-05-01 |
| CA2463798A1 (en) | 2003-07-17 |
| AU2002365141B2 (en) | 2007-06-14 |
| CA2463798C (en) | 2015-02-03 |
| KR20040047969A (ko) | 2004-06-05 |
| JP5005878B2 (ja) | 2012-08-22 |
| WO2003057822A9 (en) | 2004-07-01 |
| WO2003057822A3 (en) | 2004-02-26 |
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