AU2002346271A1 - Benzoisoselenazole derivatives with anti-inflammation, antivirus and anti-thrombosis activity and their use - Google Patents

Benzoisoselenazole derivatives with anti-inflammation, antivirus and anti-thrombosis activity and their use

Info

Publication number
AU2002346271A1
AU2002346271A1 AU2002346271A AU2002346271A AU2002346271A1 AU 2002346271 A1 AU2002346271 A1 AU 2002346271A1 AU 2002346271 A AU2002346271 A AU 2002346271A AU 2002346271 A AU2002346271 A AU 2002346271A AU 2002346271 A1 AU2002346271 A1 AU 2002346271A1
Authority
AU
Australia
Prior art keywords
derivatives
benzoisoselenazole
antivirus
inflammation
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002346271A
Other languages
English (en)
Inventor
Huihui Zeng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Peking University
Original Assignee
SCHOOL OF PHARMACEUTIC SCIENCE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SCHOOL OF PHARMACEUTIC SCIENCE filed Critical SCHOOL OF PHARMACEUTIC SCIENCE
Publication of AU2002346271A1 publication Critical patent/AU2002346271A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D293/00—Heterocyclic compounds containing rings having nitrogen and selenium or nitrogen and tellurium, with or without oxygen or sulfur atoms, as the ring hetero atoms
    • C07D293/10—Heterocyclic compounds containing rings having nitrogen and selenium or nitrogen and tellurium, with or without oxygen or sulfur atoms, as the ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D293/12—Selenazoles; Hydrogenated selenazoles

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2002346271A 2001-06-08 2002-06-10 Benzoisoselenazole derivatives with anti-inflammation, antivirus and anti-thrombosis activity and their use Abandoned AU2002346271A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN01118666.6 2001-06-08
CNB011186666A CN1166651C (zh) 2001-06-08 2001-06-08 具有抗炎和抗肿瘤作用r-双或糖苯丙异硒唑取代化合物
PCT/CN2002/000412 WO2003095436A1 (en) 2001-06-08 2002-06-10 Benzoisoselenazole derivatives with anti-inflammation, antivirus and anti-thrombosis activity and their use

Publications (1)

Publication Number Publication Date
AU2002346271A1 true AU2002346271A1 (en) 2003-11-11

Family

ID=4663351

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002346271A Abandoned AU2002346271A1 (en) 2001-06-08 2002-06-10 Benzoisoselenazole derivatives with anti-inflammation, antivirus and anti-thrombosis activity and their use

Country Status (10)

Country Link
US (2) US7495019B2 (cg-RX-API-DMAC10.html)
EP (1) EP1422225B1 (cg-RX-API-DMAC10.html)
JP (1) JP4500672B2 (cg-RX-API-DMAC10.html)
CN (1) CN1166651C (cg-RX-API-DMAC10.html)
AT (1) ATE540030T1 (cg-RX-API-DMAC10.html)
AU (1) AU2002346271A1 (cg-RX-API-DMAC10.html)
CA (1) CA2450087C (cg-RX-API-DMAC10.html)
ES (1) ES2378983T3 (cg-RX-API-DMAC10.html)
RU (1) RU2324688C2 (cg-RX-API-DMAC10.html)
WO (1) WO2003095436A1 (cg-RX-API-DMAC10.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820829B2 (en) * 2001-06-08 2010-10-26 Peking University Bisbenzisoselenazolonyl derivatives having antineoplastic, anti-inflammatory and antithrombotic activities as well as their use
CN100554255C (zh) * 2004-05-31 2009-10-28 北京大学 苯并异硒唑酮衍生物及其制备方法与应用
CN1990475B (zh) * 2005-12-29 2011-09-07 曾慧慧 取代苯并异硒唑酮类化合物及其用途
WO2007137255A2 (en) * 2006-05-22 2007-11-29 Thioredoxin Systems Ab Bacterial thioredoxin reductase inhibitors and methods for use thereof
CN101016319B (zh) * 2007-02-13 2010-08-04 中国海洋大学 苯并异硒唑酮氨基糖衍生物及其制备方法和应用
CN101781283B (zh) * 2009-01-16 2014-04-23 凯熙医药（武汉）股份有限公司 硫氧还蛋白还原酶抑制剂化合物及其制备方法和其应用
MD4014C2 (ro) * 2009-04-23 2010-09-30 Татьяна ГУЦУЛ Complecşi polioxometalaţi cu activitate antitumorală
CN101921303A (zh) * 2009-06-09 2010-12-22 曾慧慧 苯并异硒唑酮二氟胞苷类化合物及其制备方法和其用途
CN102453050B (zh) * 2010-11-03 2015-01-07 成都云克药业有限责任公司 一种二膦酸化合物及其制备方法
US8901110B2 (en) * 2012-01-13 2014-12-02 Celgene Corporation Use of biomarkers in methods for the treatment of hepatocellular carcinoma
CN103483291B (zh) * 2012-06-14 2015-08-12 沈阳药科大学 4,5-二芳基-1,3-硒唑类化合物及其制备方法和用途
CN104177312B (zh) * 2013-05-27 2018-02-13 黄英武 一种含硒化合物及其医药用途
CN105277699B (zh) * 2014-07-21 2017-05-03 武汉尚宜康健科技有限公司 测试试剂在制备评价临床肿瘤患者临床治疗监测的药品中的应用
US10058542B1 (en) 2014-09-12 2018-08-28 Thioredoxin Systems Ab Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith
CN110856717A (zh) * 2018-08-06 2020-03-03 上海元熙医药科技有限公司 一种肿瘤免疫调节剂及其用途
CN112125866B (zh) 2019-06-24 2023-04-14 上海元熙医药科技有限公司 1,4-[二(1,2-苯并异硒唑-3(2h)-酮)]丁烷的晶型及其制备方法与应用
KR20230002109A (ko) * 2021-06-29 2023-01-05 (주)라이프신약 셀레늄 화합물을 유효성분으로 포함하는 노화세포 제거용 조성물
WO2023277584A1 (ko) * 2021-06-29 2023-01-05 (주)라이프신약 셀레늄 화합물을 유효성분으로 포함하는 노화세포 제거용 조성물
CN116891443B (zh) * 2023-09-08 2023-12-01 潍坊医学院 一种异吲哚-1-酮衍生物及其制备方法、应用
WO2025169231A1 (en) * 2024-02-09 2025-08-14 Indian Institute Of Science Organoselenium compounds, preparation and implementations thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3027075A1 (de) * 1980-07-17 1982-02-18 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4531001A (en) * 1982-03-23 1985-07-23 Brigham Young University 2-β-D-ribofuranosylselenazole-4-carboxamide compounds
DE3226284A1 (de) * 1982-07-14 1984-01-19 A. Nattermann & Cie GmbH, 5000 Köln Neue benzisoselenazolone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3407511A1 (de) * 1984-03-01 1985-09-05 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolthione, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
EP0198277B1 (de) * 1985-04-12 1989-05-03 A. Nattermann & Cie. GmbH Diselenobis-benzoesäureamide primärer und sekundärer Amine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE3670635D1 (de) * 1985-04-27 1990-05-31 Nattermann A & Cie Neue benzisoselenazolonyl-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
DE3638124C2 (de) * 1986-11-08 1996-09-05 Nattermann A & Cie Neue pharmazeutische Verwendung von Ebselen
US4778814A (en) * 1987-03-18 1988-10-18 Ciba-Geigy Corporation Method of treating ocular allergy by topical application of a 2-substituted-1,2-benzisoselenazol-3(2H)-one
DE3827093A1 (de) * 1988-08-10 1990-02-15 Nattermann A & Cie Verfahren zur herstellung von hochreinem ebselen
DE4024885C2 (de) * 1990-08-06 2002-07-18 Nattermann A & Cie Verwendung von 2-Phenyl-1,2-benzisoselenazol-3(2H)-on
US5385726A (en) * 1990-08-06 1995-01-31 Rhone-Poulenc Rorer Gmbh Use of 2-phenyl-1,2-benzisoselenazol-3-(2H)-one
DE4445966A1 (de) * 1994-12-22 1996-06-27 Agfa Gevaert Ag Fotografisches Silberhalogenidmaterial
CN1110489C (zh) * 1998-11-11 2003-06-04 中国医学科学院药物研究所 苯并异硒唑酮磺酰胺衍生物及其制法和其在制备药物中的应用
US20040047852A1 (en) * 2001-03-02 2004-03-11 Kennedy Thomas Preston Method of treating cancer

Also Published As

Publication number Publication date
JP2005519991A (ja) 2005-07-07
US7495019B2 (en) 2009-02-24
EP1422225A1 (en) 2004-05-26
RU2324688C2 (ru) 2008-05-20
US20090117204A1 (en) 2009-05-07
CN1390837A (zh) 2003-01-15
US8609702B2 (en) 2013-12-17
EP1422225A4 (en) 2004-10-20
JP4500672B2 (ja) 2010-07-14
CA2450087A1 (en) 2003-11-20
RU2003134946A (ru) 2005-06-10
CN1166651C (zh) 2004-09-15
CA2450087C (en) 2012-08-07
ES2378983T3 (es) 2012-04-19
EP1422225B1 (en) 2012-01-04
US20050014801A1 (en) 2005-01-20
WO2003095436A1 (en) 2003-11-20
ATE540030T1 (de) 2012-01-15

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase
TH Corrigenda

Free format text: IN VOL 18, NO 2, PAGE(S) 580 UNDER THE HEADING APPLICATIONS OPI - NAME INDEX UNDER THE NAME PEKING UNIVERSITY, APPLICATION NO. 2002346271, UNDER INID(43) CORRECT THE PUBLICATION DATE TO READ 24.11.2003