AU2001281018A1 - Enhanced 2-keto-l-gulonic acid production - Google Patents

Enhanced 2-keto-l-gulonic acid production

Info

Publication number
AU2001281018A1
AU2001281018A1 AU2001281018A AU8101801A AU2001281018A1 AU 2001281018 A1 AU2001281018 A1 AU 2001281018A1 AU 2001281018 A AU2001281018 A AU 2001281018A AU 8101801 A AU8101801 A AU 8101801A AU 2001281018 A1 AU2001281018 A1 AU 2001281018A1
Authority
AU
Australia
Prior art keywords
host cell
dkg
keto
enhanced
klg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001281018A
Other languages
English (en)
Inventor
Veronique A. Dartois
James A. Hoch
Manoj Kumar
Fernando Valle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MicroGenomics Inc
Danisco US Inc
Original Assignee
Genencor International Inc
MicroGenomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor International Inc, MicroGenomics Inc filed Critical Genencor International Inc
Publication of AU2001281018A1 publication Critical patent/AU2001281018A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C12P7/60—2-Ketogulonic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/26—Klebsiella (G)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Laminated Bodies (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Production Of Multi-Layered Print Wiring Board (AREA)
AU2001281018A 2000-08-04 2001-08-03 Enhanced 2-keto-l-gulonic acid production Abandoned AU2001281018A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US63329400A 2000-08-04 2000-08-04
US09/633,294 2000-08-04
US67703200A 2000-09-29 2000-09-29
US09/677,032 2000-09-29
PCT/US2001/024327 WO2002012528A2 (en) 2000-08-04 2001-08-03 Enhanced 2-keto-l-gulonic acid production

Publications (1)

Publication Number Publication Date
AU2001281018A1 true AU2001281018A1 (en) 2002-02-18

Family

ID=27091840

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2001281018A Abandoned AU2001281018A1 (en) 2000-08-04 2001-08-03 Enhanced 2-keto-l-gulonic acid production
AU2001281068A Abandoned AU2001281068A1 (en) 2000-08-04 2001-08-03 2,5-dkg permeases
AU2001283132A Abandoned AU2001283132A1 (en) 2000-08-04 2001-08-03 Enhancement of industrial production by increasing substrate transport

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2001281068A Abandoned AU2001281068A1 (en) 2000-08-04 2001-08-03 2,5-dkg permeases
AU2001283132A Abandoned AU2001283132A1 (en) 2000-08-04 2001-08-03 Enhancement of industrial production by increasing substrate transport

Country Status (12)

Country Link
US (1) US20040029234A1 (de)
EP (3) EP1305423A2 (de)
JP (3) JP4975937B2 (de)
CN (3) CN1469927A (de)
AT (2) ATE510017T1 (de)
AU (3) AU2001281018A1 (de)
BR (3) BR0113036A (de)
CA (4) CA2417970C (de)
DE (1) DE60117566T2 (de)
DK (1) DK1305421T3 (de)
MX (3) MXPA03001025A (de)
WO (3) WO2002012468A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4975937B2 (ja) * 2000-08-04 2012-07-11 マイクロゲノミックス・インコーポレーテッド ２，５−ｄｋｇパーミアーゼ
US6720168B2 (en) 2000-08-04 2004-04-13 Genencor International, Inc. 2,5-DKG permeases
US7229811B2 (en) 2001-08-03 2007-06-12 Genencor International, Inc. 2,5-diketo-D-gluconic acid (2,5-DKG) permeases
CA2526595C (en) 2003-05-22 2014-10-07 Genencor International, Inc. Metabolically engineered bacterial strains having non-functional endogenous gluconate transporters
JP4742521B2 (ja) * 2003-06-05 2011-08-10 味の素株式会社 目的物質の製造法
US7335496B2 (en) 2003-06-05 2008-02-26 Ajinomoto Co., Inc. Method for producing target substance
WO2006084725A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Novel gene sts 16
JP4980651B2 (ja) * 2006-06-09 2012-07-18 Ｊｘ日鉱日石エネルギー株式会社 菌体温度を制御する能力を有する細菌
JP2016520325A (ja) * 2013-06-05 2016-07-14 ランザテク・ニュージーランド・リミテッド 発酵経路を通る流束の増加を示す、組換え微生物
CN114045243B (zh) * 2021-12-03 2023-12-26 山东天力药业有限公司 一种缩短生黑葡萄糖酸杆菌发酵周期的方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757012A (en) * 1983-06-28 1988-07-12 Genentech, Inc. Ascorbic acid intermediates and process enzymes
US5047340A (en) * 1985-06-05 1991-09-10 The University Of Kentucky Research Foundation LAC+ saccharomyces cerevisiae
US5032514A (en) * 1988-08-08 1991-07-16 Genentech, Inc. Metabolic pathway engineering to increase production of ascorbic acid intermediates
US5376544A (en) * 1992-09-08 1994-12-27 Rutgers The State University Of New Jersey Enzymes for the production of 2-keto-L-gulonic acid
JP3708543B2 (ja) * 1993-10-08 2005-10-19 ロンザ アーゲー ブチロベタイン／クロトノベタイン−ｌ−カルニチン代謝のための遺伝子およびそのｌ−カルニチンの微生物学的生産への使用
US5795716A (en) * 1994-10-21 1998-08-18 Chee; Mark S. Computer-aided visualization and analysis system for sequence evaluation
DE19523279A1 (de) * 1995-06-27 1997-01-09 Forschungszentrum Juelich Gmbh Verfahren zur mikrobiellen Herstellung von Aminosäuren mittels rekombinanter Mikroorganismen mit erhöhter Sekretionsrate
FR2736652B1 (fr) * 1995-07-13 1997-08-14 Univ Bourgogne Levures et bacteries transformees pour operer la fermentation malolactique dans les vins
US5958672A (en) * 1995-07-18 1999-09-28 Diversa Corporation Protein activity screening of clones having DNA from uncultivated microorganisms
US5795761A (en) * 1996-01-11 1998-08-18 Rutgers, The State University Of New Jersey Mutants of 2,5-diketo-D-gluconic acid (2,5-DKG) reductase A
US5783431A (en) * 1996-04-24 1998-07-21 Chromaxome Corporation Methods for generating and screening novel metabolic pathways
US5817490A (en) * 1996-05-17 1998-10-06 Eastman Chemical Company Enzymatic process for the manufacture of ascorbic acid 2-keto-L-gulonic acid and esters of 2-keto-L-gulonic acid
CN1180747A (zh) * 1996-10-18 1998-05-06 中国科学院上海生物工程研究中心 从葡萄糖发酵制备2－酮基－l－古龙酸的新方法
US5834231A (en) * 1996-10-24 1998-11-10 Archer Daniels Midland Co. Bacterial strains and use thereof in fermentation process for 2-keto-L-gulonic acid production
DE19644566A1 (de) * 1996-10-26 1998-04-30 Forschungszentrum Juelich Gmbh Mikrobielle Herstellung von Substanzen aus dem aromatischen Stoffwechsel / I
EP0839909A1 (de) * 1996-10-29 1998-05-06 Rijksuniversiteit te Groningen Nukleinsäuresequenzen die für Citrat-Transporterproteine Kodieren
CN1119414C (zh) * 1997-12-30 2003-08-27 中国科学院上海生物工程研究中心 突变的2,5二酮基－d－葡萄糖酸还原酶及其基因工程表达
US6368793B1 (en) * 1998-10-14 2002-04-09 Microgenomics, Inc. Metabolic selection methods
US6720168B2 (en) * 2000-08-04 2004-04-13 Genencor International, Inc. 2,5-DKG permeases
JP4975937B2 (ja) * 2000-08-04 2012-07-11 マイクロゲノミックス・インコーポレーテッド ２，５−ｄｋｇパーミアーゼ

Also Published As

Publication number Publication date
CA2417970A1 (en) 2002-02-14
ATE510017T1 (de) 2011-06-15
MXPA03001026A (es) 2003-09-22
EP1305423A2 (de) 2003-05-02
DK1305421T3 (da) 2006-07-10
EP1305422B1 (de) 2011-05-18
WO2002012528A3 (en) 2003-02-06
JP2004519214A (ja) 2004-07-02
EP1305421B1 (de) 2006-03-01
CN100378222C (zh) 2008-04-02
WO2002012528A2 (en) 2002-02-14
EP1305422A2 (de) 2003-05-02
EP1305421A2 (de) 2003-05-02
DE60117566D1 (de) 2006-04-27
JP4975938B2 (ja) 2012-07-11
CN1458976A (zh) 2003-11-26
AU2001283132A1 (en) 2002-02-18
CA2417970C (en) 2013-09-24
AU2001281068A1 (en) 2002-02-18
DE60117566T2 (de) 2007-01-11
ATE318907T1 (de) 2006-03-15
CA2417969A1 (en) 2002-02-14
WO2002012481A3 (en) 2002-10-10
BR0113036A (pt) 2006-02-21
MXPA03001030A (es) 2003-11-25
CN1527880A (zh) 2004-09-08
WO2002012468A2 (en) 2002-02-14
CA2417871C (en) 2011-11-15
CN100547073C (zh) 2009-10-07
BR0113032A (pt) 2006-02-21
WO2002012468A3 (en) 2002-12-05
MXPA03001025A (es) 2003-11-25
US20040029234A1 (en) 2004-02-12
JP4975937B2 (ja) 2012-07-11
CN1469927A (zh) 2004-01-21
BR0113034B1 (pt) 2014-09-16
BR0113034A (pt) 2005-08-16
CA2820132A1 (en) 2002-02-14
CA2417871A1 (en) 2002-02-14
JP2004519213A (ja) 2004-07-02
WO2002012481A2 (en) 2002-02-14
JP2004514421A (ja) 2004-05-20

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