MXPA03001030A - Permeasas del acido 2,5-diceto-d-gluconico. - Google Patents

Permeasas del acido 2,5-diceto-d-gluconico.

Info

Publication number
MXPA03001030A
MXPA03001030A MXPA03001030A MXPA03001030A MXPA03001030A MX PA03001030 A MXPA03001030 A MX PA03001030A MX PA03001030 A MXPA03001030 A MX PA03001030A MX PA03001030 A MXPA03001030 A MX PA03001030A MX PA03001030 A MXPA03001030 A MX PA03001030A
Authority
MX
Mexico
Prior art keywords
host cell
dkg
klg
transport
produce
Prior art date
Application number
MXPA03001030A
Other languages
English (en)
Inventor
Fernando Valle
Original Assignee
Microgenomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microgenomics Inc filed Critical Microgenomics Inc
Publication of MXPA03001030A publication Critical patent/MXPA03001030A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C12P7/60—2-Ketogulonic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/26—Klebsiella (G)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Laminated Bodies (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Production Of Multi-Layered Print Wiring Board (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MXPA03001030A 2000-08-04 2001-08-03 Permeasas del acido 2,5-diceto-d-gluconico. MXPA03001030A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63329400A 2000-08-04 2000-08-04
US67703200A 2000-09-29 2000-09-29
PCT/US2001/024507 WO2002012468A2 (en) 2000-08-04 2001-08-03 2,5-dkg permeases

Publications (1)

Publication Number Publication Date
MXPA03001030A true MXPA03001030A (es) 2003-11-25

Family

ID=27091840

Family Applications (3)

Application Number Title Priority Date Filing Date
MXPA03001025A MXPA03001025A (es) 2000-08-04 2001-08-03 Produccion mejorada de acido 2-ceto-l-gulonico.
MXPA03001030A MXPA03001030A (es) 2000-08-04 2001-08-03 Permeasas del acido 2,5-diceto-d-gluconico.
MXPA03001026A MXPA03001026A (es) 2000-08-04 2001-08-03 Incremento de la produccion industrial por aumentar el transporte de substratos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MXPA03001025A MXPA03001025A (es) 2000-08-04 2001-08-03 Produccion mejorada de acido 2-ceto-l-gulonico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MXPA03001026A MXPA03001026A (es) 2000-08-04 2001-08-03 Incremento de la produccion industrial por aumentar el transporte de substratos.

Country Status (12)

Country Link
US (1) US20040029234A1 (es)
EP (3) EP1305422B1 (es)
JP (3) JP4975937B2 (es)
CN (3) CN1469927A (es)
AT (2) ATE318907T1 (es)
AU (3) AU2001281018A1 (es)
BR (3) BR0113032A (es)
CA (4) CA2417969A1 (es)
DE (1) DE60117566T2 (es)
DK (1) DK1305421T3 (es)
MX (3) MXPA03001025A (es)
WO (3) WO2002012468A2 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2417969A1 (en) * 2000-08-04 2002-02-14 Genecor International, Inc. Enhancement of industrial production by increasing substrate transport
US6720168B2 (en) 2000-08-04 2004-04-13 Genencor International, Inc. 2,5-DKG permeases
US7229811B2 (en) 2001-08-03 2007-06-12 Genencor International, Inc. 2,5-diketo-D-gluconic acid (2,5-DKG) permeases
MXPA05012413A (es) 2003-05-22 2006-02-13 Genencor Int Cepas bacterianas disenadas metabolicamente que tienen transportadores de gluconato endogenos no funcionales.
JP4742521B2 (ja) * 2003-06-05 2011-08-10 味の素株式会社 目的物質の製造法
US7335496B2 (en) 2003-06-05 2008-02-26 Ajinomoto Co., Inc. Method for producing target substance
WO2006084725A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Novel gene sts 16
JP4980651B2 (ja) * 2006-06-09 2012-07-18 Ｊｘ日鉱日石エネルギー株式会社 菌体温度を制御する能力を有する細菌
CN105283554A (zh) * 2013-06-05 2016-01-27 朗泽科技新西兰有限公司 表现出提高的通过发酵途径的通量的重组微生物
CN114045243B (zh) * 2021-12-03 2023-12-26 山东天力药业有限公司 一种缩短生黑葡萄糖酸杆菌发酵周期的方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757012A (en) * 1983-06-28 1988-07-12 Genentech, Inc. Ascorbic acid intermediates and process enzymes
US5047340A (en) * 1985-06-05 1991-09-10 The University Of Kentucky Research Foundation LAC+ saccharomyces cerevisiae
US5032514A (en) * 1988-08-08 1991-07-16 Genentech, Inc. Metabolic pathway engineering to increase production of ascorbic acid intermediates
US5376544A (en) * 1992-09-08 1994-12-27 Rutgers The State University Of New Jersey Enzymes for the production of 2-keto-L-gulonic acid
KR100346293B1 (ko) * 1993-10-08 2002-11-30 론자 아게 부티로베타인/크로토노베타인-l-카르니틴대사유전자와l-카르니틴의미생물학적제조에사용되는그것의용도
US5795716A (en) * 1994-10-21 1998-08-18 Chee; Mark S. Computer-aided visualization and analysis system for sequence evaluation
DE19523279A1 (de) * 1995-06-27 1997-01-09 Forschungszentrum Juelich Gmbh Verfahren zur mikrobiellen Herstellung von Aminosäuren mittels rekombinanter Mikroorganismen mit erhöhter Sekretionsrate
FR2736652B1 (fr) * 1995-07-13 1997-08-14 Univ Bourgogne Levures et bacteries transformees pour operer la fermentation malolactique dans les vins
US5958672A (en) * 1995-07-18 1999-09-28 Diversa Corporation Protein activity screening of clones having DNA from uncultivated microorganisms
US5795761A (en) * 1996-01-11 1998-08-18 Rutgers, The State University Of New Jersey Mutants of 2,5-diketo-D-gluconic acid (2,5-DKG) reductase A
US5783431A (en) * 1996-04-24 1998-07-21 Chromaxome Corporation Methods for generating and screening novel metabolic pathways
US5817490A (en) * 1996-05-17 1998-10-06 Eastman Chemical Company Enzymatic process for the manufacture of ascorbic acid 2-keto-L-gulonic acid and esters of 2-keto-L-gulonic acid
CN1180747A (zh) * 1996-10-18 1998-05-06 中国科学院上海生物工程研究中心 从葡萄糖发酵制备2－酮基－l－古龙酸的新方法
US5834231A (en) * 1996-10-24 1998-11-10 Archer Daniels Midland Co. Bacterial strains and use thereof in fermentation process for 2-keto-L-gulonic acid production
DE19644566A1 (de) * 1996-10-26 1998-04-30 Forschungszentrum Juelich Gmbh Mikrobielle Herstellung von Substanzen aus dem aromatischen Stoffwechsel / I
EP0839909A1 (en) * 1996-10-29 1998-05-06 Rijksuniversiteit te Groningen Nucleic acid sequences encoding citrate transporter proteins
CN1119414C (zh) * 1997-12-30 2003-08-27 中国科学院上海生物工程研究中心 突变的2,5二酮基－d－葡萄糖酸还原酶及其基因工程表达
US6368793B1 (en) * 1998-10-14 2002-04-09 Microgenomics, Inc. Metabolic selection methods
US6720168B2 (en) * 2000-08-04 2004-04-13 Genencor International, Inc. 2,5-DKG permeases
CA2417969A1 (en) * 2000-08-04 2002-02-14 Genecor International, Inc. Enhancement of industrial production by increasing substrate transport

Also Published As

Publication number Publication date
WO2002012468A3 (en) 2002-12-05
WO2002012481A2 (en) 2002-02-14
JP2004519214A (ja) 2004-07-02
WO2002012468A2 (en) 2002-02-14
BR0113034A (pt) 2005-08-16
JP4975938B2 (ja) 2012-07-11
CN1527880A (zh) 2004-09-08
ATE510017T1 (de) 2011-06-15
MXPA03001025A (es) 2003-11-25
AU2001283132A1 (en) 2002-02-18
EP1305423A2 (en) 2003-05-02
WO2002012528A2 (en) 2002-02-14
WO2002012528A3 (en) 2003-02-06
ATE318907T1 (de) 2006-03-15
EP1305422B1 (en) 2011-05-18
AU2001281068A1 (en) 2002-02-18
WO2002012481A3 (en) 2002-10-10
CN1458976A (zh) 2003-11-26
JP4975937B2 (ja) 2012-07-11
BR0113032A (pt) 2006-02-21
US20040029234A1 (en) 2004-02-12
CN1469927A (zh) 2004-01-21
CN100547073C (zh) 2009-10-07
DK1305421T3 (da) 2006-07-10
MXPA03001026A (es) 2003-09-22
EP1305421B1 (en) 2006-03-01
CA2417871A1 (en) 2002-02-14
DE60117566D1 (de) 2006-04-27
CA2820132A1 (en) 2002-02-14
EP1305422A2 (en) 2003-05-02
JP2004519213A (ja) 2004-07-02
AU2001281018A1 (en) 2002-02-18
JP2004514421A (ja) 2004-05-20
EP1305421A2 (en) 2003-05-02
BR0113036A (pt) 2006-02-21
BR0113034B1 (pt) 2014-09-16
CA2417970A1 (en) 2002-02-14
CA2417970C (en) 2013-09-24
CA2417871C (en) 2011-11-15
CN100378222C (zh) 2008-04-02
DE60117566T2 (de) 2007-01-11
CA2417969A1 (en) 2002-02-14

Similar Documents

Publication Publication Date Title
MXPA05012230A (es) Codificacion de longitud de cuadro variable optimizada en fidelidad.
EP0913466A3 (en) Method for producing L-leucine
EP1283265A4 (en) PROCESS FOR THE PRODUCTION OF PROTEIN WITH ACIDIC ACID SACCHAROSE CHAIN REDUCTION AND RESULTING GLYCOPROTEIN
BR0200452A (pt) Método para produzir ácido l-glut mico pela fermentação
EP1180371A4 (en) AGENTS PROMOTING THE FORMATION OF A BASIC SKIN MEMBRANE, AGENTS PROMOTING THE FORMATION OF ARTIFICIAL SKIN AND METHOD FOR PRODUCING ARTIFICIAL SKIN
ATE311460T1 (de) Hefestämme zur herstellung von milchsäure
MX359740B (es) Produccion fermentativa de alcoholes de cuatro atomos de carbono.
MXPA03001030A (es) Permeasas del acido 2,5-diceto-d-gluconico.
BR0012712A (pt) Métodos de produção de l-aminoácidos aumentando-se o nadph celular
EP1154020A3 (en) Arginine repressor deficient strain of coryneform bacterium and method for producing L-arginine
CY1110827T1 (el) Μια μεθοδος παραγωγης ηλεκτρικου οξεος απο ακατεργαστα υδρολυματα
IN2002MU01763A (es)
WO2000056903A3 (en) IMPROVED METHODS FOR PRODUCING PROTEINS IN TRANSFORMED $i(PICHIA)
GB0203307D0 (en) Method
TWI255855B (en) Process for preparing O-acetyl-l-serine by fermentation
EP0891702A4 (es)
MY128886A (en) Method for producing l-glutamic acid.
PT1680150E (pt) Material compósito contendo hidrogel preparado por precipitação de uma fase sólida desencadeada electricamente
AU2003273521A1 (en) Production method of iturin a and its homologues
AU3109300A (en) Production of ascorbic acid using yeast
AU2002226308A1 (en) Method for producing dnda
FR2815640B1 (fr) Procede de production de proteines par electropulsation de levures
MXPA02002583A (es) Procedimiento de preparacion de una beta-ciclodextrina directamente compresible, y beta-ciclodextrina directamente compresible asi obtenida.
AU2002216102A1 (en) Method for producing biomass
WO2002022527A3 (en) Design and production of mutant 2,5-diketo-d-gluconic acid reductase enzymes with altered cofactor dependency

Legal Events

Date Code Title Description
FG Grant or registration