ATE85361T1 - Molekulare zuechtung. - Google Patents

Molekulare zuechtung.

Info

Publication number
ATE85361T1
ATE85361T1 AT86905070T AT86905070T ATE85361T1 AT E85361 T1 ATE85361 T1 AT E85361T1 AT 86905070 T AT86905070 T AT 86905070T AT 86905070 T AT86905070 T AT 86905070T AT E85361 T1 ATE85361 T1 AT E85361T1
Authority
AT
Austria
Prior art keywords
plant
plant cells
expression
physiologically active
constructs
Prior art date
Application number
AT86905070T
Other languages
English (en)
Inventor
Robert M Goodman
Vic C Knauf
Catherine M Houck
Luca Comai
Original Assignee
Calgene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25058500&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE85361(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Calgene Inc filed Critical Calgene Inc
Application granted granted Critical
Publication of ATE85361T1 publication Critical patent/ATE85361T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/57IFN-gamma
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Surface Treatment Of Optical Elements (AREA)
AT86905070T 1985-07-29 1986-07-29 Molekulare zuechtung. ATE85361T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/760,236 US4956282A (en) 1985-07-29 1985-07-29 Mammalian peptide expression in plant cells
PCT/US1986/001599 WO1987000865A1 (en) 1985-07-29 1986-07-29 Molecular farming
EP86905070A EP0233915B1 (de) 1985-07-29 1986-07-29 Molekulare züchtung

Publications (1)

Publication Number Publication Date
ATE85361T1 true ATE85361T1 (de) 1993-02-15

Family

ID=25058500

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86905070T ATE85361T1 (de) 1985-07-29 1986-07-29 Molekulare zuechtung.

Country Status (8)

Country Link
US (5) US4956282A (de)
EP (1) EP0233915B1 (de)
JP (1) JPS63500425A (de)
AT (1) ATE85361T1 (de)
AU (1) AU603063B2 (de)
CA (1) CA1340696C (de)
DE (1) DE3687705T2 (de)
WO (1) WO1987000865A1 (de)

Families Citing this family (204)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182200A (en) * 1985-04-22 1993-01-26 Lubrizol Genetics, Inc. T-dna promoters
US4956282A (en) * 1985-07-29 1990-09-11 Calgene, Inc. Mammalian peptide expression in plant cells
US6774283B1 (en) * 1985-07-29 2004-08-10 Calgene Llc Molecular farming
CA1324096C (en) * 1987-04-27 1993-11-09 Stephen Gary Rogers Gentamicin marker genes for plant transformation
WO1989003887A1 (en) * 1987-10-20 1989-05-05 Plant Genetic Systems N.V. A process for the production of biologically active peptide via the expression of modified storage seed protein genes in transgenic plants
EP0723019B1 (de) * 1987-10-20 2006-01-18 Bayer BioScience N.V. 5'-flankierende Region eines Genes von Arabidopsis, das für einen 2S Albumin-Prekursor kodiert
ATE316144T1 (de) * 1987-10-20 2006-02-15 Bayer Bioscience Nv 5'-flankierende region eines genes von arabidopsis, das für einen 2s albumin-prekursor kodiert
EP0318341B1 (de) * 1987-10-20 1996-07-31 Plant Genetic Systems, N.V. Verfahren zur Herstellung transgenetischer Pflanzen mit erhöhtem Nährwert durch Expression von modifizierten 2S-Speicheralbuminen in diesen Pflanzen
EP0319353B1 (de) * 1987-10-20 1996-10-02 Plant Genetic Systems N.V. Verfahren zur Herstellung eines biologisch-aktiven Peptides durch Expression von modifizierten Speicherproteingenen in transgenetischen Pflanzen
US6846968B1 (en) * 1988-02-26 2005-01-25 Large Scale Biology Corporation Production of lysosomal enzymes in plants by transient expression
US20040093646A1 (en) * 1988-02-26 2004-05-13 Erwin Robert L. Production of lysosomal enzymes in plants by transient expression
EP0428572A1 (de) * 1988-07-29 1991-05-29 Washington University School Of Medicine Herstellung von kommerziell wertvollen polypeptiden durch genetisch transformierte endospermgewebe
CA1341467C (en) * 1988-07-29 2004-12-07 John C. Rogers Producing commercially valuable polypeptides with genetically transformed endosperm tissue
WO1990002484A1 (en) * 1988-09-06 1990-03-22 Washington University Oral immunization by transgenic plants
US5589615A (en) * 1988-10-14 1996-12-31 Plant Genetic Systems N.V. Process for the production of transgenic plants with increased nutritional value via the expression of modified 2S storage albumins
US5428146A (en) * 1988-11-07 1995-06-27 Max-Planck-Gesellschaft Zur Forderung Wound-stimulated DNA-sequence from solanum tuberosum and its use
US5000740A (en) * 1989-04-10 1991-03-19 Critikon, Inc. Catheter with needle guard
NL8901932A (nl) * 1989-07-26 1991-02-18 Mogen Int Produktie van heterologe eiwitten in planten of plantecellen.
US7705215B1 (en) 1990-04-17 2010-04-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US6803499B1 (en) 1989-08-09 2004-10-12 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
EP0412911B1 (de) * 1989-08-10 2001-07-18 Aventis CropScience N.V. Pflanzen mit modifizierten Blüten
US6995014B1 (en) * 1989-10-27 2006-02-07 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
US7005560B1 (en) 1989-10-27 2006-02-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
US7037722B1 (en) 1989-10-27 2006-05-02 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
US5202422A (en) * 1989-10-27 1993-04-13 The Scripps Research Institute Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use
US5959177A (en) * 1989-10-27 1999-09-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
US5658772A (en) * 1989-12-22 1997-08-19 E. I. Du Pont De Nemours And Company Site-specific recombination of DNA in plant cells
US6946587B1 (en) * 1990-01-22 2005-09-20 Dekalb Genetics Corporation Method for preparing fertile transgenic corn plants
US6329574B1 (en) 1990-01-22 2001-12-11 Dekalb Genetics Corporation High lysine fertile transgenic corn plants
US6777589B1 (en) 1990-01-22 2004-08-17 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US6025545A (en) * 1990-01-22 2000-02-15 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
CA2074355C (en) 1990-01-22 2008-10-28 Ronald C. Lundquist Method of producing fertile transgenic corn plants
WO1991013993A1 (en) * 1990-03-05 1991-09-19 The Upjohn Company Protein expression via seed specific regulatory sequences
KR100225087B1 (ko) * 1990-03-23 1999-10-15 한스 발터라벤 피타아제의 식물내 발현
IL97645A (en) * 1990-03-23 1997-03-18 Gist Brocades Nv Production of enzymes in seeds and their use
US5593963A (en) * 1990-09-21 1997-01-14 Mogen International Expression of phytase in plants
US5543576A (en) * 1990-03-23 1996-08-06 Mogen International Production of enzymes in seeds and their use
US7033627B2 (en) 1990-03-23 2006-04-25 Syngenta Mogen B.V. Production of enzymes in seeds and their use
US5750875A (en) * 1990-06-11 1998-05-12 Stalker; David M. Glycogen biosynthetic enzymes in plants
US5969214A (en) * 1990-06-11 1999-10-19 Calgene, Inc. Glycogen biosynthetic enzymes in plants
DK162790D0 (da) * 1990-07-06 1990-07-06 Novo Nordisk As Plantecelle
US6395966B1 (en) 1990-08-09 2002-05-28 Dekalb Genetics Corp. Fertile transgenic maize plants containing a gene encoding the pat protein
US5306862A (en) * 1990-10-12 1994-04-26 Amoco Corporation Method and composition for increasing sterol accumulation in higher plants
JPH06504914A (ja) * 1991-02-25 1994-06-09 ゼネカ・リミテッド 新しく特性決定されたシュウ酸塩オキシダーゼ及びその使用
GB9108386D0 (en) * 1991-04-19 1991-06-05 Agricultural Genetics Co Modified plant viruses as vectors
US6034298A (en) * 1991-08-26 2000-03-07 Prodigene, Inc. Vaccines expressed in plants
US5484719A (en) * 1991-08-26 1996-01-16 Edible Vaccines, Inc. Vaccines produced and administered through edible plants
US5612487A (en) * 1991-08-26 1997-03-18 Edible Vaccines, Inc. Anti-viral vaccines expressed in plants
US20010053367A1 (en) * 1991-08-26 2001-12-20 Prodigene, Inc. Vaccines expressed in plants
ATE194656T1 (de) * 1992-04-28 2000-07-15 Nihon Nohyaku Co Ltd Verfahren zur herstellung eines fremden gens oder dessen produkt in pflanzenzellen
EP1568778A1 (de) * 1992-06-30 2005-08-31 Smithkline Beecham Plc Hydantoinase aus Agrobacterium
HU219140B (hu) * 1992-11-30 2001-02-28 Zeneca Ltd. Oxalát-dekarboxilázt kódoló izolált DNS fragmens, az azt tartalmazó rekombináns molekula, és a rekombináns molekulát tartalmazó transzformált növényi sejtek
ES2213747T3 (es) * 1993-07-01 2004-09-01 California Institute Of Technology Plantas que tienen una respuesta modificada al etileno.
US5689055A (en) * 1993-07-01 1997-11-18 California Institue Of Technology Plants having modified response to ethylene
US6281411B1 (en) 1993-08-25 2001-08-28 Dekalb Genetics Corporation Transgenic monocots plants with increased glycine-betaine content
US6326527B1 (en) 1993-08-25 2001-12-04 Dekalb Genetics Corporation Method for altering the nutritional content of plant seed
US6118047A (en) 1993-08-25 2000-09-12 Dekalb Genetic Corporation Anthranilate synthase gene and method of use thereof for conferring tryptophan overproduction
US5693506A (en) * 1993-11-16 1997-12-02 The Regents Of The University Of California Process for protein production in plants
US5792935A (en) * 1993-12-09 1998-08-11 Texas A&M University Agrobacterium tumefaciens transformation of Musa species
US6140075A (en) * 1994-07-25 2000-10-31 Monsanto Company Method for producing antibodies and protein toxins in plant cells
US6080560A (en) * 1994-07-25 2000-06-27 Monsanto Company Method for producing antibodies in plant cells
US5723755A (en) * 1995-05-16 1998-03-03 Francis E. Lefaivre Large scale production of human or animal proteins using plant bioreactors
US5723764A (en) * 1995-06-07 1998-03-03 Pioneer Hi-Bred International, Inc. Cellulose synthesis in the storage tissue of transgenic plants
WO1997004123A1 (en) * 1995-07-19 1997-02-06 Gel Tech Group Inc. Collagen compound production in plants
US6020169A (en) * 1995-07-20 2000-02-01 Washington State University Research Foundation Production of secreted foreign polypeptides in plant cell culture
ES2326705T3 (es) * 1995-09-14 2009-10-16 Virginia Tech Intellectual Properties, Inc. Produccion de enzimas lisosomicas en sistemas de expresion basados en plantas.
WO1997010347A1 (en) * 1995-09-15 1997-03-20 Howard John A Expression cassettes and methods for delivery of animal vaccines
US5824870A (en) * 1995-11-06 1998-10-20 Baszczynski; Chris Commercial production of aprotinin in plants
US5767379A (en) * 1995-11-06 1998-06-16 John Howard Commercial production of avidin in plants
US20020124278A1 (en) * 1996-02-09 2002-09-05 Niu Man C. Methods for effectuating mRNA transfer of genetic information between species and product of the same
US5855881A (en) * 1996-02-22 1999-01-05 Loike; John D. Mammalian alcohol dehydrogenase and aldehyde dehydrogenase production in plants
US6042832A (en) * 1996-08-28 2000-03-28 Thomas Jefferson University Polypeptides fused with alfalfa mosaic virus or ilarvirus capsid proteins
AU4173497A (en) * 1996-09-03 1998-03-26 Monsanto Company Monocot seed gene expression system
US5981835A (en) * 1996-10-17 1999-11-09 Wisconsin Alumni Research Foundation Transgenic plants as an alternative source of lignocellulosic-degrading enzymes
US7361331B2 (en) * 1996-10-18 2008-04-22 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food Plant bioreactors
WO1998021348A1 (en) * 1996-11-12 1998-05-22 Battelle Memorial Institute Method of producing human growth factors from whole plants or plant cell cultures
FR2757874B1 (fr) * 1996-12-17 2003-04-25 Biocem Collagenes recombinants et proteines derivees produits par les plantes, leurs procedes d'obtention et leurs utilisations
AU2217897A (en) * 1997-03-20 1998-10-12 Gel Tech Group Inc. Mammalian alcohol dehydrogenase and aldehyde dehydrogenase production in plants
US6818803B1 (en) 1997-06-26 2004-11-16 Wisconsin Alumni Research Foundation Transgenic plants as an alternative source of lignocellulosic-degrading enzymes
US6639050B1 (en) * 1997-07-21 2003-10-28 Ohio University Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins
US7378506B2 (en) * 1997-07-21 2008-05-27 Ohio University Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins
US7741536B2 (en) 1997-08-07 2010-06-22 University Of Central Florida Research Foundation, Inc. Expression of human serum albumin in plastids
ES2244073T5 (es) 1997-08-07 2009-02-01 Auburn University Vectores universales de integracion y de expresion de cloroplastos, y plantas transformadas.
US20030204864A1 (en) * 2001-02-28 2003-10-30 Henry Daniell Pharmaceutical proteins, human therapeutics, human serum albumin, insulin, native cholera toxic b submitted on transgenic plastids
US7161064B2 (en) * 1997-08-12 2007-01-09 North Carolina State University Method for producing stably transformed duckweed using microprojectile bombardment
US6040498A (en) * 1998-08-11 2000-03-21 North Caroline State University Genetically engineered duckweed
US7265267B1 (en) * 1997-09-16 2007-09-04 Cropdesign N.V. Cyclin-dependent kinase inhibitors and uses thereof
WO1999014331A2 (en) * 1997-09-16 1999-03-25 Cropdesign Nv Cyclin-dependent kinase inhibitors and uses thereof
US20050186219A1 (en) * 1997-10-07 2005-08-25 Langridge William H. Transgenic plant-based vaccines
US6777546B2 (en) * 1997-10-07 2004-08-17 Loma Linda University Methods and substances for preventing and treating autoimmune disease
US20050241024A1 (en) * 1997-10-07 2005-10-27 Langridge William H Transgenic plant-based vaccines
US7422747B2 (en) * 1997-10-07 2008-09-09 Loma Linda University Transgenic plant-based vaccines
US20080256663A1 (en) * 1997-11-24 2008-10-16 Andersen Scott E Nucleic acid molecules and other molecules associated with plants
US7625738B1 (en) 1997-11-24 2009-12-01 Monsanto Technology Llc Nucleic acid molecules encoding a ferrochelatase enzyme or fragment thereof
US7572902B2 (en) * 1997-12-09 2009-08-11 Monsanto Technology Llc Nucleic acid molecules seq id No. 16372 and other molecules associated with plants
US7919608B2 (en) * 1997-11-24 2011-04-05 Monsanto Technology Llc Nucleic acid molecules and other molecules associated with plants
US7655777B2 (en) * 1997-11-24 2010-02-02 Monsanto Technology Llc Nucleic acid molecules associated with the tocopherol pathway
US20030027173A1 (en) * 1998-01-16 2003-02-06 Della-Cioppa Guy Method of determining the function of nucleotide sequences and the proteins they encode by transfecting the same into a host
US6468745B1 (en) 1998-01-16 2002-10-22 Large Scale Biology Corporation Method for expressing a library of nucleic acid sequence variants and selecting desired traits
US6426185B1 (en) * 1998-01-16 2002-07-30 Large Scale Biology Corporation Method of compiling a functional gene profile in a plant by transfecting a nucleic acid sequence of a donor plant into a different host plant in an anti-sense orientation
US6303848B1 (en) 1998-01-16 2001-10-16 Large Scale Biology Corporation Method for conferring herbicide, pest, or disease resistance in plant hosts
US20060253933A1 (en) * 1998-02-10 2006-11-09 Brown Sherri M Nucleic acid molecules and other molecules associated with the gibberellin pathway
US20100251425A9 (en) 1998-05-15 2010-09-30 University Of Central Florida Expression of human interferon in transgenic chloroplasts
US6117797A (en) * 1998-09-03 2000-09-12 Micron Technology, Inc. Attachment method for heat sinks and devices involving removal of misplaced encapsulant
AU6166499A (en) * 1998-09-30 2000-04-17 Regents Of The University Of California, The Inhibition of farnesyltransferase activity in plants
US6696619B1 (en) * 1998-11-05 2004-02-24 Omolayo O. Famodu Plant aminoacyl-tRNA synthetases
EP2264177B1 (de) 1998-12-09 2015-09-30 Phyton Holdings, LLC Glycoprotein mit menschlichem Glycosylierungsbild
EP1140043B1 (de) * 1998-12-22 2005-03-02 National Research Council Of Canada Transgene pflanzen mit konditional lethalem gen
US6515206B1 (en) * 1998-12-23 2003-02-04 Calgene Llc Plastid transformation of Brassica
US6982363B1 (en) * 1999-02-10 2006-01-03 E.I. Du Pont De Nemours And Company UDP-glucose modifiers
US6835868B1 (en) 1999-03-17 2004-12-28 University Of Victoria Innovation And Development Corporation Transgenic plants expressing dermaseptin peptides providing broad spectrum resistance to pathogens
US20070011783A1 (en) * 1999-05-06 2007-01-11 Jingdong Liu Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
US7868149B2 (en) * 1999-07-20 2011-01-11 Monsanto Technology Llc Plant genome sequence and uses thereof
US7560542B2 (en) * 1999-05-07 2009-07-14 Monsanto Technology Llc Nucleic acid molecule SEQ ID NO. 68811 and other molecules associated with plants
WO2000068392A1 (en) 1999-05-11 2000-11-16 The Board Of Trustees Of The University Of Illinois Plant-derived antigens against respiratory syncytial virus
US20070150978A1 (en) * 1999-05-17 2007-06-28 Byrum Joseph R Nucleic acid molecules and other molecules associated with plants
US6395962B1 (en) 1999-06-22 2002-05-28 University Of South Carolina Enhancing expression of a silenced target sequence in plants using plant viral enhancers and amplicons
US20040111765A1 (en) * 1999-06-25 2004-06-10 Oishi Karen K. Production of urokinase in plant-based expression systems
USRE46192E1 (en) 1999-07-20 2016-11-01 Monsanto Technology Llc Rice metallothionein promoters
US7365185B2 (en) * 2000-07-19 2008-04-29 Monsanto Technology Llc Genomic plant sequences and uses thereof
US8058516B2 (en) 2000-07-19 2011-11-15 Monsanto Technology Llc Rice metallothionein promoters
US20060242729A1 (en) * 1999-07-30 2006-10-26 Cahoon Edgar B Polynucleotides encoding proteins involved in plant metabolism
US6916971B1 (en) * 1999-07-30 2005-07-12 Rebecca E. Cahoon Polynucleotides encoding aminolevulinic acid biosynthetic enzymes
US7557201B2 (en) * 1999-09-21 2009-07-07 Monsanto Technology Llc Nucleic acid molecules and other molecules associated with plants
US6740526B1 (en) * 1999-09-22 2004-05-25 Wayne R. Curtis Quantitative transient protein expression in plant tissue culture
US7553954B2 (en) * 1999-09-22 2009-06-30 Monsanto Technology Llc Nucleic acid molecules and other molecules associated with plants
US20070016974A1 (en) * 1999-09-30 2007-01-18 Byrum Joseph R Nucleic acid molecules and other molecules associated with plants
US6573426B1 (en) * 1999-09-30 2003-06-03 E.I. Du Pont De Nemours & Company Gene involved in pyrimidine biosynthesis in plants
NZ518532A (en) 1999-10-26 2004-02-27 Plant Res Internat B Transgenic plant expressing mammalian beta-1,4- galactosyltransferase
ES2349427T3 (es) * 1999-10-26 2011-01-03 Stichting Dienst Landbouwkundig Onderzoek Glicosilación de tipo mamífero en plantas.
US20040253586A1 (en) * 1999-12-08 2004-12-16 Siva Reddy Plastid transformation
EP1254156A4 (de) * 2000-01-27 2003-05-21 Univ Loma Linda Auf transgene pflanzen basierender impstoff
ATE510916T1 (de) * 2000-03-01 2011-06-15 Univ Auburn Plastidtransformationsvektoren zur expression von proinsulin, das an die cholera toxin b- untereinheit fusioniert ist, in pflanzen
US6703540B1 (en) * 2000-03-09 2004-03-09 The United States Of America As Represented By The Secretary Of Agriculture Transformation of plants with a chloroperoxidase gene to enhance disease resistance
US20070083945A1 (en) * 2000-03-10 2007-04-12 Byrum Joseph R Nucleic acid molecules and other molecules associated with plants
US6770799B2 (en) * 2000-03-17 2004-08-03 Thompson Boyce Plant Res Expression of recombinant human acetylcholinesterase in transgenic plants
US6696620B2 (en) 2000-05-02 2004-02-24 Epicyte Pharmaceutical, Inc. Immunoglobulin binding protein arrays in eukaryotic cells
FR2809416B1 (fr) * 2000-05-29 2004-12-10 Tabacs & Allumettes Ind Clonage et sequencage de l'allergene dac g5 du pollen de dactilys glomerata, sa preparation et son utilisation
DE60125170T2 (de) * 2000-06-05 2008-01-24 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food In pflanzen erzeugte rekombinante proteinuntereinheit eines parvovirus vom schwein
EP1296710A4 (de) * 2000-06-19 2004-05-12 Rahan Meristem Rekombinanter impfstoff gegen das für die bursal-krankheit verantwortliche virus(03.01.02)
AR030430A1 (es) * 2000-06-29 2003-08-20 Sungene Gmbh & Co Kgaa Procedimiento para la obtencion de quimicos finos por cultivo de organismos que presentan una via de shiquimato modificada, composicion de acido nucleinico, uso de dicho acido nucleinico para la obtencion de plantas transgenicas, organismo geneticamente modificado, procedimiento para la produccion d
ES2640613T3 (es) * 2000-07-21 2017-11-03 Revance Therapeutics, Inc. Sistemas de transporte de agentes biológicos de múltiples componentes
US20040010817A1 (en) * 2000-07-21 2004-01-15 Washington State University Research Foundation Plant acyl-CoA synthetases
NZ523912A (en) 2000-07-31 2005-03-24 Biolex Inc Expression of biologically active polypeptides in duckweed
US7959910B2 (en) 2000-07-31 2011-06-14 Biolex Therapeutics, Inc. C-terminally truncated interferon alpha variants
US8022270B2 (en) * 2000-07-31 2011-09-20 Biolex Therapeutics, Inc. Expression of biologically active polypeptides in duckweed
US7632983B2 (en) * 2000-07-31 2009-12-15 Biolex Therapeutics, Inc. Expression of monoclonal antibodies in duckweed
US20060265782A1 (en) * 2000-08-29 2006-11-23 Hinkle Gregory J Novel plant transcribed regions and uses thereof
US20070067865A1 (en) * 2000-09-05 2007-03-22 Kovalic David K Annotated plant genes
US6784341B2 (en) * 2000-09-14 2004-08-31 Pioneer Hi-Bred International, Inc. Defense-related signaling genes and methods of use
WO2002043650A2 (en) * 2000-11-28 2002-06-06 Virogene Ltd. Systems and methods for delivering interferon to a subject
US20060064782A1 (en) * 2000-12-18 2006-03-23 Conopco, Inc. Production of antibodies
US6806401B2 (en) * 2000-12-27 2004-10-19 Pioneer Hi-Bred International, Inc. OAR polynucleotides, polypeptides and their use in PHA production in plants
WO2002057468A2 (en) 2001-01-19 2002-07-25 The Dow Chemical Company Method for secretory production of glycoprotein having human-type sugar chain using plant cell
WO2002067663A1 (en) * 2001-02-27 2002-09-06 Multigenesis Corporation Methods for effectuating mrna-mediated transfer of genetic information into plants and products of the same
CN101781635A (zh) * 2001-03-06 2010-07-21 陶氏化学公司 具有动物型糖链加成功能的植物细胞
WO2002099067A2 (en) 2001-06-05 2002-12-12 Oishi Karen K Gene expression and production of tgf-b proteins including bioactive mullerian inhibiting substance from plants
US20030084482A1 (en) * 2001-06-08 2003-05-01 Gerald Hall Production of proteins in plants
ITRM20010332A1 (it) * 2001-06-11 2002-12-11 Ist Superiore Sanita Vaccini a subunita' e procedimenti per la loro produzione.
JP2005510207A (ja) * 2001-07-27 2005-04-21 イコン ジェネティクス インコーポレイティッド 人及び動物の治療用又は診断用タンパク質を製造するための、アラビドプシスの工業的利用
US20090158452A1 (en) * 2001-12-04 2009-06-18 Johnson Richard G Transgenic plants with enhanced agronomic traits
AR037699A1 (es) * 2001-12-04 2004-12-01 Monsanto Technology Llc Maiz transgenico con fenotipo mejorado
US20030217384A1 (en) * 2002-02-05 2003-11-20 Harvell Leslie T. Obtusifoliol 14a-demethylase
US20040040061A1 (en) * 2002-02-27 2004-02-26 Michael Horn Expression in plants of HIV-related proteins
EP1481010A2 (de) * 2002-02-28 2004-12-01 Eli Lilly And Company Anti-interleukin-1-beta-analoga
AU2003213815A1 (en) * 2002-03-08 2003-09-22 Prodigene, Inc. Production of insulin and insulin-like proteins in plants
CA2819867A1 (en) 2002-03-19 2003-09-25 Stichting Dienst Landbouwkundig Onderzoek Gntiii (udp-n-acetylglucosamine:beta-d mannoside beta (1,4)-n-acetylglucosaminyltransferase iii) expression in plants
CA2923247A1 (en) * 2002-03-19 2003-09-25 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
US7238854B2 (en) * 2002-04-11 2007-07-03 E. I. Du Pont De Nemours And Company Method of controlling site-specific recombination
US6776751B2 (en) * 2002-04-22 2004-08-17 Kendor Laboratory Products, Lp Rotor cover attachment apparatus
WO2004005343A1 (en) * 2002-07-02 2004-01-15 Nexgen Biotechnologies, Inc. Production of transformed plants expressing thyroid stimulating hormone receptor
CA2491639A1 (en) * 2002-07-03 2004-01-15 University Of Central Florida Expression of the human igf-1 in transgenic plastids
CA2492544A1 (en) * 2002-08-02 2004-02-12 Basf Plant Science Gmbh Modification of seed oil by the expression of a putative cytidyltransferase in transgenic plants
US6920521B2 (en) * 2002-10-10 2005-07-19 International Business Machines Corporation Method and system of managing virtualized physical memory in a data processing system
EP1629090B1 (de) * 2002-11-06 2014-03-05 iBio, Inc. Expression von fremdsequenzen in pflanzen unter verwendung eines trans-aktivierungssystems
US7692063B2 (en) * 2002-11-12 2010-04-06 Ibio, Inc. Production of foreign nucleic acids and polypeptides in sprout systems
US8148608B2 (en) 2004-02-20 2012-04-03 Fraunhofer Usa, Inc Systems and methods for clonal expression in plants
US7683238B2 (en) * 2002-11-12 2010-03-23 iBio, Inc. and Fraunhofer USA, Inc. Production of pharmaceutically active proteins in sprouted seedlings
AR042145A1 (es) * 2002-11-27 2005-06-08 Dow Agrociences Llc Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
TW201139672A (en) 2002-12-13 2011-11-16 Novartis Ag Immunization of fish with plant-expressed recombinant proteins
ES2531125T3 (es) * 2003-02-03 2015-03-10 Ibio Inc Sistema para la expresión de genes en plantas
US20040173547A1 (en) * 2003-03-06 2004-09-09 Roth Michael Carl Bolt on attachment to facilitate hanging of pneumatic tool
KR100546066B1 (ko) * 2003-03-21 2006-01-26 한국생명공학연구원 베타아밀로이드 유전자의 다중 연결체를 발현하는 형질전환 식물 세포 및 이로부터 배양된 식물
US20040216190A1 (en) * 2003-04-28 2004-10-28 Kovalic David K. Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
US20060252120A1 (en) * 2003-05-09 2006-11-09 Kieliszewski Marcia J Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins
AR044803A1 (es) * 2003-06-17 2005-10-05 Sembiosys Genetics Inc Metodos para la produccion de insulina
TW200526778A (en) * 2003-11-14 2005-08-16 Sembiosys Genetics Inc Methods for the production of apolipoproteins in transgenic plants
EP1711533B1 (de) * 2004-01-14 2013-12-11 Ohio University Verfahren zur Herstellung von Peptiden/Proteinen in Pflanzen und dadurch hergestellte Peptide/Proteine
US20070180585A1 (en) * 2004-03-17 2007-08-02 Bala Rathinasabapathi Increased stress tolerance and enhanced yield in plants
CA2573918A1 (en) 2004-04-19 2005-11-24 Ohio University Cross-linkable glycoproteins and methods of making the same
US8148603B2 (en) * 2004-05-24 2012-04-03 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O.), Volcani Center Transgenic ficus, method for producing same and use thereof
WO2006005362A1 (en) * 2004-07-13 2006-01-19 Paion Deutschland Gmbh Production of mammalian proteins in plant cells
US20060024272A1 (en) * 2004-07-29 2006-02-02 Large Scale Biology Corporation C-terminally truncated interferon
US20070261132A1 (en) * 2004-08-11 2007-11-08 Basf Plant Science Gmbh Nucleic Acids Conferring Lipid and Sugar Alterations in Plants ll
JP4948412B2 (ja) * 2004-09-23 2012-06-06 バイエル・クロップサイエンス・アーゲー ヒアルロナンを製造するための方法および手段
US7582817B2 (en) * 2005-03-23 2009-09-01 E.I. Du Pont De Nemours And Company Alteration of plant embryo/endosperm size during development
WO2007008708A2 (en) * 2005-07-08 2007-01-18 Ohio University Methods of predicting hyp-glycosylation sites for proteins expressed and secreted in plant cells, and related methods and products
US8993846B2 (en) 2005-09-06 2015-03-31 Monsanto Technology Llc Vectors and methods for improved plant transformation efficiency
TW201808334A (zh) * 2007-02-09 2018-03-16 艾瑟勒朗法瑪公司 包含ActRIIa-Fc融合蛋白的醫藥組合物;ActRIIa-Fc融合蛋白於治療或預防與癌症相關的骨質流失之用途;ActRIIa-Fc融合蛋白於治療或預防多發性骨髓瘤之用途
WO2008121154A2 (en) * 2007-03-31 2008-10-09 Rutgers, The State University Of New Jersey Nucleic acid sequences for biosynthesis of non -mccj25-related lariat peptides
EP2147108B1 (de) * 2007-04-17 2014-03-05 Stichting Dienst Landbouwkundig Onderzoek Säugerartige glykosylierung in pflanzen durch expression von nichtsäuger-glykosyltransferasen
NZ600007A (en) * 2009-11-18 2014-08-29 Agriculture Victoria Serv Pty Angiogenin expression in plants
US10150970B2 (en) 2011-07-27 2018-12-11 Applied Biotechnology Institute, Inc. Methods to increase antigenicity of membrane-bound polypeptides produced in plants
US11344835B2 (en) 2018-08-21 2022-05-31 Donaldson Company, Inc. Filter assembly for an enclosure

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS215108B2 (en) * 1977-07-15 1982-07-30 Wellcome Found Method of making the interferrone
US4278661A (en) * 1979-10-12 1981-07-14 E. I. Du Pont De Nemours And Company Purification of interferon
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
US4399216A (en) * 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
IL66614A (en) * 1981-08-28 1985-09-29 Genentech Inc Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it
JPH0787797B2 (ja) * 1982-05-20 1995-09-27 サントリー株式会社 ヒト・ガンマ・インタ−フエロン様ポリペプチドの製造法
IL69382A (en) * 1982-08-05 1991-01-31 Carter William Alvin Method of protecting plants against viral pathogens by inserting into plant cells genes encoding polypeptides containing interferon domains
IL70022A0 (en) * 1982-11-08 1984-01-31 Standard Oil Co Method for introducing foreign genes into green algae cells utilizing t-dna of agrobacterium
EP0131620B1 (de) * 1983-01-17 1991-08-21 Monsanto Company Genetisch transformierte pflanzen
WO1984002919A1 (en) * 1983-01-17 1984-08-02 Monsanto Co Plasmids for transforming plant cells
WO1984002913A1 (en) * 1983-01-17 1984-08-02 Monsanto Co Chimeric genes suitable for expression in plant cells
US5102796A (en) * 1983-04-15 1992-04-07 Lubrizol Genetics, Inc. Plant structural gene expression
CA1278540C (en) * 1983-07-22 1991-01-02 Eli Lilly And Company Modified antibiotic resistance gene
IL72666A0 (en) * 1983-08-15 1984-11-30 Stauffer Chemical Co Plasmid vector
US4771002A (en) * 1984-02-24 1988-09-13 Lubrizol Genetics, Inc. Transcription in plants and bacteria
EP0179861A1 (de) * 1984-04-19 1986-05-07 Agracetus Verfahren und vektoren für die transformation von pflanzenzellen
AU6137986A (en) * 1985-07-16 1987-02-10 Salk Institute For Biological Studies, The Genetic alteration of plants with retroviruses
US4956282A (en) * 1985-07-29 1990-09-11 Calgene, Inc. Mammalian peptide expression in plant cells
NL8901932A (nl) * 1989-07-26 1991-02-18 Mogen Int Produktie van heterologe eiwitten in planten of plantecellen.
IT1264083B1 (it) * 1993-12-10 1996-09-10 Enea Ente Nuove Tec Procedimento per la produzione in piante di anticorpi ingegnerizzati, anticorpi prodotti e loro uso in diagnosi e terapia.

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EP0233915A4 (de) 1988-03-23
AU6196686A (en) 1987-03-05
JPS63500425A (ja) 1988-02-18
US5550038A (en) 1996-08-27
EP0233915A1 (de) 1987-09-02
US4956282A (en) 1990-09-11
AU603063B2 (en) 1990-11-08
US5629175A (en) 1997-05-13
DE3687705D1 (de) 1993-03-18
CA1340696C (en) 1999-08-10
US6096547A (en) 2000-08-01
US20010049830A1 (en) 2001-12-06
WO1987000865A1 (en) 1987-02-12
DE3687705T2 (de) 1993-07-08

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