ATE82588T1 - Zuchtverfahren fuer leukocyten. - Google Patents

Zuchtverfahren fuer leukocyten.

Info

Publication number
ATE82588T1
ATE82588T1 AT87903509T AT87903509T ATE82588T1 AT E82588 T1 ATE82588 T1 AT E82588T1 AT 87903509 T AT87903509 T AT 87903509T AT 87903509 T AT87903509 T AT 87903509T AT E82588 T1 ATE82588 T1 AT E82588T1
Authority
AT
Austria
Prior art keywords
leukocytes
culturing
cultivation procedure
cultivation
procedure
Prior art date
Application number
AT87903509T
Other languages
English (en)
Inventor
Georgiann B Melink
Raji A Shankar
Original Assignee
Endotronics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endotronics Inc filed Critical Endotronics Inc
Application granted granted Critical
Publication of ATE82588T1 publication Critical patent/ATE82588T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/10—Hollow fibers or tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT87903509T 1986-04-28 1987-04-27 Zuchtverfahren fuer leukocyten. ATE82588T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85682786A 1986-04-28 1986-04-28
PCT/US1987/000924 WO1987006610A1 (en) 1986-04-28 1987-04-27 Method of culturing leukocytes
EP87903509A EP0302894B1 (de) 1986-04-28 1987-04-27 Zuchtverfahren für leukocyten

Publications (1)

Publication Number Publication Date
ATE82588T1 true ATE82588T1 (de) 1992-12-15

Family

ID=25324599

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87903509T ATE82588T1 (de) 1986-04-28 1987-04-27 Zuchtverfahren fuer leukocyten.

Country Status (6)

Country Link
US (2) US5541105A (de)
EP (1) EP0302894B1 (de)
JP (1) JP2529321B2 (de)
AT (1) ATE82588T1 (de)
DE (1) DE3782736T2 (de)
WO (1) WO1987006610A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3786978T2 (de) * 1986-09-29 1994-03-03 Suzuki Shokan Co Verfahren für die Zuführung von Kulturmedium und Kultursystem.
AU2925789A (en) * 1987-12-17 1989-07-19 Browning's Clinical Pathology Services Limited Lymphokine activation of cells for adoptive immunotherapy, e.g. of hiv infection
US4999298A (en) * 1988-04-27 1991-03-12 W. R. Grace & Co.-Conn. Hollow fiber bioreactor culture system and method
CA2015294A1 (en) * 1989-04-28 1990-10-28 John J. Rinehart Generation and expansion of lak cells
GR1001034B (el) * 1989-07-21 1993-03-31 Ortho Pharma Corp Μεθοδος διεγερσης του πολλαπλασιασμου λεμφοκυτταρων περιφερειακου αιματος.
JPH05502369A (ja) * 1989-09-14 1993-04-28 セルコ、インコーポレイテッド 養子免疫療法に用いられる生体外増殖リンパ性細胞の製造方法
WO1991018972A1 (en) * 1990-05-30 1991-12-12 Cellco, Inc. Culturing bone marrow cells for adoptive immunotherapy
EP0552372B1 (de) * 1991-07-04 1999-06-02 Japan Tobacco Inc. Verfahren zur kultivierung von vorläufer t-zellinien
AU2873999A (en) 1998-02-24 1999-09-06 Sisters Of Providence In Oregon Compositions containing an OX-40 receptor binding agent or nucleic acid encoding the same and methods for enhancing antigen-specific immune response
DE19945162A1 (de) * 1999-09-21 2001-04-26 Herbert Maerkl Verfahren zur Kultivierung von Zellen, Membranmodul, Verwendung eines Membranmoduls und Reaktionssystem zur Kultivierung von Zellen
WO2007139747A1 (en) 2006-05-22 2007-12-06 Biovest International Inc. Interface of a cultureware module in a cell culture system and installation method thereof
JP2010519937A (ja) 2007-03-05 2010-06-10 カリディアンビーシーティー、インコーポレーテッド 細胞増殖システムおよび使用方法
WO2008109668A2 (en) * 2007-03-05 2008-09-12 Caridianbct, Inc. Methods to control cell movement in hollow fiber bioreactors
KR20100016187A (ko) * 2007-04-06 2010-02-12 카리디안비씨티, 인크. 개선된 생물반응기 표면
US8906688B2 (en) * 2007-04-13 2014-12-09 Terumo Bct, Inc. Cell expansion system and methods of use
WO2011140231A1 (en) 2010-05-05 2011-11-10 Caridianbct, Inc. Method of reseeding adherent cells grown in a hollow fiber bioreactor system
WO2012048275A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
WO2012171030A2 (en) 2011-06-10 2012-12-13 Biovest International, Inc. Method and apparatus for antibody production and purification
WO2012171026A2 (en) 2011-06-10 2012-12-13 Biovest International, Inc. Methods for high yield virus production
DE102011106914B4 (de) 2011-07-08 2015-08-27 Zellwerk Gmbh Mäander- Bioreaktor und Verfahren zu dynamischen Expansion, Differenzierung und Ernte von hämatopoetischen Zellen
JP2015504413A (ja) 2011-10-28 2015-02-12 パトリス リミテッド Ｐａｔ−ｌｍ１エピトープおよびそれを使用するための方法
US9175259B2 (en) 2012-08-20 2015-11-03 Terumo Bct, Inc. Method of loading and distributing cells in a bioreactor of a cell expansion system
CA2920957A1 (en) 2012-08-28 2014-03-06 Biovest International, Inc. Biomanufacturing suite and methods for large-scale production of cells, viruses, and biomolecules
WO2014036488A1 (en) 2012-08-31 2014-03-06 Biovest International, Inc. Methods for producing high-fidelity autologous idiotype vaccines
DK2951208T3 (da) 2013-02-01 2020-01-13 Kira Biotech Pty Ltd Anti-cd83 antistoffer og anvendelse deraf
EP3068867B1 (de) 2013-11-16 2018-04-18 Terumo BCT, Inc. Zellenexpansion in einem bioreaktor
EP3122866B1 (de) 2014-03-25 2019-11-20 Terumo BCT, Inc. Passives ersetzen von medien
WO2015164808A1 (en) 2014-04-24 2015-10-29 Terumo Bct, Inc. Measuring flow rate
CN106715676A (zh) 2014-09-26 2017-05-24 泰尔茂比司特公司 按计划供养
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
EP3464565A4 (de) 2016-05-25 2020-01-01 Terumo BCT, Inc. Zellexpansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
CN117247899A (zh) 2017-03-31 2023-12-19 泰尔茂比司特公司 细胞扩增
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515894A (en) * 1979-03-20 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing monoclonal antibody to human T cells
US4515893A (en) * 1979-04-26 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells
US4515895A (en) * 1979-04-26 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing monoclonal antibody to human helper T cells
JPS5642584A (en) * 1979-09-18 1981-04-20 Asahi Chem Ind Co Ltd Cell cultivation method
US4364932A (en) * 1979-09-18 1982-12-21 Ortho Pharmaceutical Corporation Monoclonal antibody to human cytotoxic and suppressor T cells and methods of preparing same
US4444887A (en) * 1979-12-10 1984-04-24 Sloan-Kettering Institute Process for making human antibody producing B-lymphocytes
US4438032A (en) * 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
US4464355A (en) * 1981-03-26 1984-08-07 Hooper Trading Co. Serum-free and mitogen-free T-cell growth factor and process for making same
US4401756A (en) * 1981-04-14 1983-08-30 Immunex Corporation Process for preparing human interleukin 2
US4473642A (en) * 1981-04-29 1984-09-25 Immunex Corporation Constitutive production of interleukin 2 by a T cell hybridoma
US4407945A (en) * 1981-04-29 1983-10-04 Immunex Corporation Constitutive production of interleukin 2 by a T cell hybridoma
US4544632A (en) * 1981-06-12 1985-10-01 Yuichi Yamamura Human T cell lines and method of producing same
US4404280A (en) * 1981-07-16 1983-09-13 Steven Gillis Process for preparing murine interleukin 2 in the presence of interleukin 1 from an interleukin 2 nonproducer malignant cell line and cell line therefor
US4490289A (en) * 1982-09-16 1984-12-25 Hoffmann-La Roche Inc. Homogeneous human interleukin 2
JPS60137284A (ja) * 1983-12-23 1985-07-20 Sumitomo Chem Co Ltd 抗体産生細胞の取得方法、及びそれを用いた抗体の製造方法
US4804628A (en) * 1984-10-09 1989-02-14 Endotronics, Inc. Hollow fiber cell culture device and method of operation
JPS61280270A (ja) * 1985-06-03 1986-12-10 Teijin Ltd 細胞培養装置
US4690915A (en) * 1985-08-08 1987-09-01 The United States Of America As Represented By The Department Of Health And Human Services Adoptive immunotherapy as a treatment modality in humans

Also Published As

Publication number Publication date
DE3782736D1 (de) 1992-12-24
DE3782736T2 (de) 1993-06-09
EP0302894A4 (de) 1989-02-06
EP0302894A1 (de) 1989-02-15
JPH01502315A (ja) 1989-08-17
US5541105A (en) 1996-07-30
EP0302894B1 (de) 1992-11-19
US5631006A (en) 1997-05-20
WO1987006610A1 (en) 1987-11-05
JP2529321B2 (ja) 1996-08-28

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