GB9818730D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collections of compounds
|
DK1109812T3
(da)
|
1998-08-27 |
2005-09-05 |
Spirogen Ltd |
Pyrrolobenzodiazepiner
|
GB0226593D0
(en)
|
2002-11-14 |
2002-12-24 |
Consultants Ltd |
Compounds
|
GB0321295D0
(en)
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
EP2270010B1
(de)
|
2004-03-01 |
2012-01-25 |
Spirogen Limited |
11-hydroxy-5h-pyrrolo[2,1-c][1,4]benzodiazepin-5-on derivate als zwischenverbindungen für die herstellung von c2 substituierten pyrrolobenzodiazepinen
|
GB0404574D0
(en)
*
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Amino acids
|
GB0404577D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
EP1723152B1
(de)
|
2004-03-09 |
2015-02-11 |
Spirogen Sàrl |
Pyrrolobenzodiazepine
|
GB0410725D0
(en)
*
|
2004-05-13 |
2004-06-16 |
Spirogen Ltd |
Pyrrolobenzodiazepine therapeutic agents
|
DE602006011300D1
(de)
*
|
2005-04-21 |
2010-02-04 |
Spirogen Ltd |
Pyrrolobenzodiazepine
|
ATE427949T1
(de)
*
|
2005-10-05 |
2009-04-15 |
Spirogen Ltd |
4-a4-(5-oxo-2,3,5,11a-tetrahydro-5h-pyrrolo a2, 1-cua1,4ubenzodiazepin-8-yloxy)-butyrylaminou-1 - pyrrol-2-carbonsaurealkylesterderivate und verwandte verbindung zur behandlung einer proliferativen erkrankung
|
GB0813432D0
(en)
*
|
2008-07-22 |
2008-08-27 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
GB0819097D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
GB0819095D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
KR101738203B1
(ko)
*
|
2010-04-15 |
2017-05-19 |
메디뮨 리미티드 |
피롤로벤조디아제핀 및 그의 컨주게이트
|
AU2011239522B2
(en)
|
2010-04-15 |
2014-10-23 |
Medimmune Limited |
Targeted pyrrolobenzodiazapine conjugates
|
AU2011239525B2
(en)
*
|
2010-04-15 |
2015-04-09 |
Medimmune Limited |
Pyrrolobenzodiazepines used to treat proliferative diseases
|
GB201006340D0
(en)
|
2010-04-15 |
2010-06-02 |
Spirogen Ltd |
Synthesis method and intermediates
|
EP2668210B1
(de)
|
2011-01-26 |
2020-06-17 |
Celldex Therapeutics, Inc. |
Anti-kit-antikörper und ihre verwendungen
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
AU2012311505B2
(en)
|
2011-09-20 |
2016-09-29 |
Medimmune Limited |
Pyrrolobenzodiazepines as unsymmetrical dimeric PBD compounds for inclusion in targeted conjugates
|
AU2012322933B2
(en)
|
2011-10-14 |
2017-02-02 |
Medimmune Limited |
Synthesis method and intermediates useful in the preparation of pyrrolobenzodiazepines
|
US9526798B2
(en)
*
|
2011-10-14 |
2016-12-27 |
Seattle Genetics, Inc. |
Pyrrolobenzodiazepines and targeted conjugates
|
KR101891859B1
(ko)
*
|
2011-10-14 |
2018-08-24 |
메디뮨 리미티드 |
피롤로벤조디아제핀
|
JP6117801B2
(ja)
*
|
2011-10-14 |
2017-04-19 |
メドイミューン・リミテッドMedImmune Limited |
ピロロベンゾジアゼピン
|
EA036202B1
(ru)
|
2011-10-14 |
2020-10-14 |
Сиэтл Дженетикс, Инк. |
Пирролбензодиазепины и конъюгаты направленного действия
|
EP2750713B1
(de)
|
2011-10-14 |
2015-09-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine und konjugate daraus
|
WO2013092983A2
(en)
|
2011-12-23 |
2013-06-27 |
Innate Pharma |
Enzymatic conjugation of polypeptides
|
JP6401060B2
(ja)
|
2012-02-24 |
2018-10-03 |
アッヴィ・ステムセントルクス・エル・エル・シー |
抗sez6抗体及び使用方法
|
DK2817338T3
(en)
|
2012-02-24 |
2017-10-23 |
Abbvie Stemcentrx Llc |
DLL3 modulators and methods of use
|
AU2013255613B2
(en)
|
2012-04-30 |
2017-06-22 |
Medimmune Limited |
Pyrrolobenzodiazepines
|
US9321774B2
(en)
|
2012-04-30 |
2016-04-26 |
Medimmune Limited |
Pyrrolobenzodiazepines
|
WO2014009426A2
(en)
|
2012-07-13 |
2014-01-16 |
Innate Pharma |
Screening of conjugated antibodies
|
US9334332B2
(en)
|
2012-07-25 |
2016-05-10 |
Kolltan Pharmaceuticals, Inc. |
Anti-kit antibodies
|
BR112015008238A2
(pt)
|
2012-10-12 |
2017-11-28 |
Adc Therapeutics Sarl |
conjugados de pirrolbenzodiazepina-anticorpo anti-cd22
|
SI2906253T1
(sl)
|
2012-10-12 |
2018-11-30 |
Adc Therapeutics Sa |
Konjugati pirolobenzodiazepin-protitelo proti PSMA
|
WO2014057120A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
ES2680153T3
(es)
|
2012-10-12 |
2018-09-04 |
Adc Therapeutics Sa |
Conjugados de anticuerpos anti-PSMA-pirrolobenzodiazepinas
|
HUE045435T2
(hu)
|
2012-10-12 |
2019-12-30 |
Medimmune Ltd |
Pirrolobenzodiazepinek és konjugátumaik
|
AU2013328625B2
(en)
|
2012-10-12 |
2016-12-15 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
HUE042731T2
(hu)
|
2012-10-12 |
2019-07-29 |
Adc Therapeutics Sa |
Pirrolobenzodiazepin-antitest konjugátumok
|
EP2906248B1
(de)
*
|
2012-10-12 |
2018-12-05 |
MedImmune Limited |
Pyrrolobenzodiazepine und konjugate davon
|
SI2906252T1
(sl)
*
|
2012-10-12 |
2017-10-30 |
Adc Therapeutics Sa |
Pirolobenzodiazepin-anti-HER2 protitelesni konjugati
|
AU2013328673B2
(en)
|
2012-10-12 |
2017-07-13 |
Medimmune Limited |
Synthesis and intermediates of pyrrolobenzodiazepine derivatives for conjugation
|
EP3564259A3
(de)
|
2012-11-09 |
2020-02-12 |
Innate Pharma |
Kennungen für tgase-vermittelte konjugation
|
US10131682B2
(en)
|
2012-11-24 |
2018-11-20 |
Hangzhou Dac Biotech Co., Ltd. |
Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules
|
EA032986B1
(ru)
|
2012-12-21 |
2019-08-30 |
Медимьюн Лимитед |
Пирролобензодиазепины
|
JP6307519B2
(ja)
|
2012-12-21 |
2018-04-04 |
メドイミューン・リミテッドMedImmune Limited |
ピロロベンゾジアゼピンおよびその結合体
|
MX2015010682A
(es)
|
2013-02-22 |
2016-05-31 |
Stemcentrx Inc |
Nuevos conjugados de anticuerpos y usos de los mismos.
|
CA2905181C
(en)
|
2013-03-13 |
2020-06-02 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof for providing targeted therapy
|
EA027910B1
(ru)
|
2013-03-13 |
2017-09-29 |
Медимьюн Лимитед |
Пирролобензодиазепины и их конъюгаты
|
JP6340019B2
(ja)
|
2013-03-13 |
2018-06-06 |
メドイミューン・リミテッドMedImmune Limited |
ピロロベンゾジアゼピン及びそのコンジュゲート
|
EP2968582B1
(de)
|
2013-03-15 |
2020-07-01 |
Innate Pharma |
Festphasen-tgase-vermittelte konjugation von antikörpern
|
US10071169B2
(en)
|
2013-06-20 |
2018-09-11 |
Innate Pharma |
Enzymatic conjugation of polypeptides
|
JP6744212B2
(ja)
|
2013-06-21 |
2020-08-19 |
イナート・ファルマ・ソシエテ・アノニムInnate Pharma Pharma S.A. |
ポリペプチドの酵素的結合
|
EP3892294A1
(de)
|
2013-08-28 |
2021-10-13 |
AbbVie Stemcentrx LLC |
Konjugationsverfahren stellenspezifischer antikörper und zusammensetzungen
|
EP3338793A1
(de)
|
2013-08-28 |
2018-06-27 |
AbbVie Stemcentrx LLC |
Neuartige sez6-modulatoren und verfahren zur verwendung
|
MX2016003256A
(es)
|
2013-09-12 |
2016-06-07 |
Halozyme Inc |
Anticuerpos modificados del receptor de factor de crecimiento anti-epidermico y metodos de uso de los mismos.
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
WO2015052534A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
US9956299B2
(en)
|
2013-10-11 |
2018-05-01 |
Medimmune Limited |
Pyrrolobenzodiazepine—antibody conjugates
|
EP3054983B1
(de)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepin-antikörper-konjugate
|
RU2016122041A
(ru)
|
2013-11-06 |
2017-12-11 |
ЭББВИ СТЕМСЕНТРКС ЭлЭлСи |
Новые анти-клаудин антитела и способы их применения
|
CA2932476A1
(en)
|
2013-12-12 |
2015-06-18 |
Stemcentrx, Inc. |
Novel anti-dpep3 antibodies and methods of use
|
JP2017514143A
(ja)
|
2014-02-21 |
2017-06-01 |
アッヴィ・ステムセントルクス・エル・エル・シー |
メラノーマに使用するための抗dll3抗体および薬物コンジュゲート
|
US10464955B2
(en)
|
2014-02-28 |
2019-11-05 |
Hangzhou Dac Biotech Co., Ltd. |
Charged linkers and their uses for conjugation
|
TW202214691A
(zh)
|
2014-03-21 |
2022-04-16 |
美商艾伯維有限公司 |
抗-egfr抗體及抗體藥物結合物
|
US10160812B2
(en)
|
2014-04-11 |
2018-12-25 |
Medimmune, Llc |
Bispecific HER2 antibodies
|
GB201407816D0
(en)
|
2014-05-02 |
2014-06-18 |
King S College London |
Pyrrolobenzodiazepine Compounds
|
TW201617368A
(zh)
|
2014-09-05 |
2016-05-16 |
史坦森特瑞斯公司 |
新穎抗mfi2抗體及使用方法
|
US10188746B2
(en)
|
2014-09-10 |
2019-01-29 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
EA201790545A1
(ru)
|
2014-09-12 |
2017-07-31 |
Дженентек, Инк. |
Антитела и иммуноконъюгаты против her2
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
MX2017003523A
(es)
|
2014-09-17 |
2017-11-08 |
Genentech Inc |
Pirrolobenzodiazepinas y conjugados de anticuerpo-disulfuro de las mismas.
|
JP6863888B2
(ja)
|
2014-10-01 |
2021-04-21 |
メディミューン,エルエルシー |
ポリペプチドをコンジュゲートさせる方法
|
CN107148285B
(zh)
|
2014-11-25 |
2022-01-04 |
Adc治疗股份有限公司 |
吡咯并苯并二氮杂䓬-抗体缀合物
|
EP3229838B1
(de)
|
2014-12-11 |
2020-09-09 |
Pierre Fabre Medicament |
Anti-c10orf54-antikörper und verwendungen davon
|
WO2016115201A1
(en)
|
2015-01-14 |
2016-07-21 |
Bristol-Myers Squibb Company |
Heteroarylene-bridged benzodiazepine dimers, conjugates thereof, and methods of making and using
|
BR112017014599A2
(pt)
|
2015-01-14 |
2018-01-16 |
Bristol-Myers Squibb Company |
dímeros de benzodiazepina, conjugados dos mesmos, e métodos de preparação e uso
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
KR20180019592A
(ko)
|
2015-06-23 |
2018-02-26 |
브리스톨-마이어스 스큅 컴퍼니 |
마크로시클릭 벤조디아제핀 이량체, 그의 접합체, 제조법 및 용도
|
CN113350518A
(zh)
|
2015-07-12 |
2021-09-07 |
杭州多禧生物科技有限公司 |
与细胞结合分子的共轭偶联的桥连接体
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
US9873708B2
(en)
*
|
2015-07-21 |
2018-01-23 |
Immunogen, Inc. |
Methods of preparing cytotoxic benzodiazepine derivatives
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
US11414477B2
(en)
|
2016-01-27 |
2022-08-16 |
Medimmune, Llc |
Methods for preparing antibodies with a defined glycosylation pattern
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
WO2017161206A1
(en)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugates containing conditionally active antibodies or antigen-binding fragments thereof, and methods of use
|
MY198114A
(en)
|
2016-04-15 |
2023-08-04 |
Macrogenics Inc |
Novel b7-h3-binding molecules, antibody drug conjugates thereof and methods of use thereof
|
EP3454864A4
(de)
|
2016-04-21 |
2021-01-13 |
Abbvie Stemcentrx LLC |
Neuartige anti-bmpr1b-antikörper und verfahren zur verwendung
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
WO2017214456A1
(en)
|
2016-06-08 |
2017-12-14 |
Abbvie Inc. |
Anti-cd98 antibodies and antibody drug conjugates
|
CN109563167A
(zh)
|
2016-06-08 |
2019-04-02 |
艾伯维公司 |
抗b7-h3抗体和抗体药物偶联物
|
WO2017214335A1
(en)
|
2016-06-08 |
2017-12-14 |
Abbvie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
CA3027103A1
(en)
|
2016-06-08 |
2017-12-14 |
Abbvie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
EP3468599A2
(de)
|
2016-06-08 |
2019-04-17 |
AbbVie Inc. |
Anti-cd98-antikörper und antikörperwirkstoffkonjugate
|
CN109862919A
(zh)
|
2016-10-11 |
2019-06-07 |
免疫医疗有限公司 |
抗体-药物缀合物联合免疫介导的治疗剂
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
NZ752394A
(en)
|
2016-11-14 |
2021-07-30 |
Hangzhou Dac Biotech Co Ltd |
Conjugation linkers, cell binding molecule-drug conjugates containing the likers, methods of making and uses such conjugates with the linkers
|
WO2018138032A2
(en)
|
2017-01-24 |
2018-08-02 |
Innate Pharma |
NKp46 BINDING AGENTS
|
US20200023071A1
(en)
|
2017-02-06 |
2020-01-23 |
Innate Pharma |
Immunomodulatory antibody drug conjugates binding to a human mica polypeptide
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
JP6671555B2
(ja)
|
2017-02-08 |
2020-03-25 |
アーデーセー セラピューティクス ソシエテ アノニム |
ピロロベンゾジアゼピン抗体複合体
|
TW201836647A
(zh)
|
2017-04-06 |
2018-10-16 |
美商艾伯維有限公司 |
抗-prlr抗體藥物軛合物(adc)及其用途
|
AU2018255876B2
(en)
|
2017-04-18 |
2020-04-30 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
AU2018253948A1
(en)
|
2017-04-20 |
2019-09-19 |
Adc Therapeutics Sa |
Combination therapy with an anti-AXL Antibody-Drug Conjugate
|
AR111963A1
(es)
|
2017-05-26 |
2019-09-04 |
Univ California |
Método y moléculas
|
MX2019015042A
(es)
|
2017-06-14 |
2020-08-06 |
Adc Therapeutics Sa |
Regimen de dosificacion.
|
KR102270107B1
(ko)
|
2017-08-18 |
2021-06-30 |
메디뮨 리미티드 |
피롤로벤조디아제핀 컨쥬게이트
|
CN111164208B
(zh)
|
2017-09-29 |
2023-08-04 |
第一三共株式会社 |
抗体-吡咯并苯并二氮杂卓衍生物偶联物
|
WO2019092148A1
(en)
|
2017-11-10 |
2019-05-16 |
Innate Pharma |
Antibodies with functionalized glutamine residues
|
ES2920123T3
(es)
|
2017-11-14 |
2022-08-01 |
Medimmune Ltd |
Conjugados de pirrolobenzodiazepina
|
EP3724225A1
(de)
|
2017-12-15 |
2020-10-21 |
Juno Therapeutics, Inc. |
Anti-cct5-bindende moleküle und verfahren zur verwendung davon
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
EP3801630A1
(de)
|
2018-05-25 |
2021-04-14 |
Medimmune Limited |
Pyrrolobenzodiazepinkonjugate
|
US20210316006A1
(en)
|
2018-10-19 |
2021-10-14 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
EP3866856A1
(de)
|
2018-10-19 |
2021-08-25 |
MedImmune Limited |
Pyrrolobenzodiazepinkonjugate
|
SG11202108900WA
(en)
|
2019-03-15 |
2021-09-29 |
Medimmune Ltd |
Azetidobenzodiazepine dimers and conjugates comprising them for use in the treatment of cancer
|
WO2022112356A1
(en)
|
2020-11-25 |
2022-06-02 |
Innate Pharma |
Treatment of cancer
|
UY39610A
(es)
|
2021-01-20 |
2022-08-31 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
GB202105187D0
(en)
|
2021-04-12 |
2021-05-26 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
GB202105186D0
(en)
|
2021-04-12 |
2021-05-26 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
US11807685B2
(en)
|
2021-08-05 |
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The Uab Research Foundation |
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