DE60224289D1 - 1,3-glyceridverbindung mit zwei iodphenylgruppen - Google Patents
1,3-glyceridverbindung mit zwei iodphenylgruppenInfo
- Publication number
- DE60224289D1 DE60224289D1 DE60224289T DE60224289T DE60224289D1 DE 60224289 D1 DE60224289 D1 DE 60224289D1 DE 60224289 T DE60224289 T DE 60224289T DE 60224289 T DE60224289 T DE 60224289T DE 60224289 D1 DE60224289 D1 DE 60224289D1
- Authority
- DE
- Germany
- Prior art keywords
- iodphenyl
- groups
- independently represent
- glyceride compound
- iodine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/82—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/83—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of an acyclic saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0461—Dispersions, colloids, emulsions or suspensions
- A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/708—Ethers
- C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
- C07C69/736—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fats And Perfumes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001253395 | 2001-08-23 | ||
JP2001253395 | 2001-08-23 | ||
JP2002182351 | 2002-06-24 | ||
JP2002182351 | 2002-06-24 | ||
PCT/JP2002/008461 WO2003018530A1 (fr) | 2001-08-23 | 2002-08-22 | Compose 1,3-glyceride comportant deux groupes iodophenyl |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60224289D1 true DE60224289D1 (de) | 2008-02-07 |
DE60224289T2 DE60224289T2 (de) | 2009-01-02 |
Family
ID=26620882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60224289T Expired - Lifetime DE60224289T2 (de) | 2001-08-23 | 2002-08-22 | 1,3-glyceridverbindung mit zwei iodphenylgruppen |
Country Status (6)
Country | Link |
---|---|
US (1) | US7264790B2 (de) |
EP (1) | EP1426353B1 (de) |
JP (1) | JP4198592B2 (de) |
AT (1) | ATE382033T1 (de) |
DE (1) | DE60224289T2 (de) |
WO (1) | WO2003018530A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005048987A1 (en) * | 2003-11-21 | 2005-06-02 | Fuji Photo Film Co., Ltd. | Contrast medium comprising liposomes containing hydrophobic chelate compound |
JP2006335745A (ja) * | 2005-06-06 | 2006-12-14 | Fujifilm Holdings Corp | リポソームを含むmri造影剤 |
JP5064761B2 (ja) * | 2005-12-21 | 2012-10-31 | 富士フイルム株式会社 | ジエチレントリアミン型金属キレート構造を有する高級脂肪酸トリエステル及びアミド誘導体 |
CN112933255A (zh) * | 2020-12-17 | 2021-06-11 | 太阳雨林(厦门)生物医药有限公司 | 一种负载放射性核素碘油制剂及其制备方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4873075A (en) * | 1985-09-10 | 1989-10-10 | The University Of Michigan | Polyiodinated triglyceride analogs as radiologic agents |
AU5260301A (en) * | 2000-04-28 | 2001-11-12 | Fuji Photo Film Co Ltd | Liposomes containing hydrophobic iodo compound |
US20030194372A1 (en) * | 2000-06-08 | 2003-10-16 | Hu Liu | Radioimaging probes and the use thereof |
-
2002
- 2002-08-22 DE DE60224289T patent/DE60224289T2/de not_active Expired - Lifetime
- 2002-08-22 AT AT02758864T patent/ATE382033T1/de not_active IP Right Cessation
- 2002-08-22 US US10/487,319 patent/US7264790B2/en not_active Expired - Fee Related
- 2002-08-22 EP EP02758864A patent/EP1426353B1/de not_active Expired - Lifetime
- 2002-08-22 WO PCT/JP2002/008461 patent/WO2003018530A1/ja active IP Right Grant
- 2002-08-22 JP JP2003523195A patent/JP4198592B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2003018530A1 (fr) | 2003-03-06 |
EP1426353A4 (de) | 2006-03-01 |
DE60224289T2 (de) | 2009-01-02 |
ATE382033T1 (de) | 2008-01-15 |
JPWO2003018530A1 (ja) | 2004-12-09 |
US20050002864A1 (en) | 2005-01-06 |
US7264790B2 (en) | 2007-09-04 |
EP1426353A1 (de) | 2004-06-09 |
EP1426353B1 (de) | 2007-12-26 |
JP4198592B2 (ja) | 2008-12-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8381 | Inventor (new situation) |
Inventor name: TAKAHASHI, KAZUNOBU, MINAMI-ASHIGARA-SHI, KANA, JP Inventor name: KITAGUCHI, HIROSHI, MINAMI-ASHIGARA-SHI, KANAG, JP Inventor name: AIKAWA, KAZUHIRO, MINAMI-ASHIGARA-SHI, KANAGAW, JP |
|
8364 | No opposition during term of opposition |