ATE233264T1 - Polynalbuphinderivat - Google Patents

Polynalbuphinderivat

Info

Publication number
ATE233264T1
ATE233264T1 AT00303532T AT00303532T ATE233264T1 AT E233264 T1 ATE233264 T1 AT E233264T1 AT 00303532 T AT00303532 T AT 00303532T AT 00303532 T AT00303532 T AT 00303532T AT E233264 T1 ATE233264 T1 AT E233264T1
Authority
AT
Austria
Prior art keywords
polynalbuphine
derivative
chem
substituted
compound
Prior art date
Application number
AT00303532T
Other languages
English (en)
Inventor
Oliver Yoa-Pu Hu
Cheng-Huei Hsiong
Original Assignee
Oliver Yoa-Pu Hu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oliver Yoa-Pu Hu filed Critical Oliver Yoa-Pu Hu
Application granted granted Critical
Publication of ATE233264T1 publication Critical patent/ATE233264T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
AT00303532T 2000-04-27 2000-04-27 Polynalbuphinderivat ATE233264T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00303532A EP1149836B1 (de) 2000-04-27 2000-04-27 Polynalbuphinderivat

Publications (1)

Publication Number Publication Date
ATE233264T1 true ATE233264T1 (de) 2003-03-15

Family

ID=8172948

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00303532T ATE233264T1 (de) 2000-04-27 2000-04-27 Polynalbuphinderivat

Country Status (4)

Country Link
EP (1) EP1149836B1 (de)
AT (1) ATE233264T1 (de)
DE (1) DE60001487T2 (de)
ES (1) ES2188481T3 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005009377A2 (en) * 2003-07-23 2005-02-03 University Of Kentucky Research Foundation Novel oral bioavailable prodrugs
PT2402005T (pt) 2005-08-24 2021-04-14 Endo Pharmaceuticals Inc Formulações de libertação sustentada de nalbufina
US8394812B2 (en) 2005-08-24 2013-03-12 Penwest Pharmaceuticals Co. Sustained release formulations of nalbuphine
US10736889B2 (en) * 2011-04-29 2020-08-11 Rutgers, The State University Of New Jersey Method of treating dyskinesia
US9918980B2 (en) * 2011-04-29 2018-03-20 Rutgers, The State University Of New Jersey Method of treating dyskinesia
EP2701707B1 (de) 2011-04-29 2020-09-02 Rutgers, the State University of New Jersey Verfahren zur behandlung von dyskinesie
TWI729371B (zh) * 2018-03-29 2021-06-01 順天醫藥生技股份有限公司 治療搔癢症的組合物與方法
WO2020012245A1 (en) 2018-07-13 2020-01-16 Alkermes Pharma Ireland Limited Thienothiophene-naltrexone prodrugs for long-acting injectable compositions
US10799496B2 (en) 2018-07-13 2020-10-13 Alkermes Pharma Ireland Limited Naphthylenyl compounds for long-acting injectable compositions and related methods
US11186585B2 (en) 2018-08-17 2021-11-30 Kappa-Pharma LLC Compositions and methods of enhancing opioid receptor engagement by opioid hexadienoates and optionally substituted hexadienoates
US10975099B2 (en) 2018-11-05 2021-04-13 Alkermes Pharma Ireland Limited Thiophene compounds for long-acting injectable compositions and related methods
MX2022001520A (es) 2019-08-11 2022-07-21 Kappa Pharma Llc Composiciones y metodos para mejorar activacion de receptor de opioide por hexadienoatos opioides y hexadienoatos opcionalmente sustituidos.
EP4087569A4 (de) 2020-01-10 2024-01-24 Trevi Therapeutics, Inc. Verfahren zur verabreichung von nalbuphin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2323192A1 (de) * 1972-05-10 1973-12-13 Endo Lab Injizierbare, langwirkende antagonistpraeparate gegen narkotika und rauschgifte
US4668685A (en) * 1984-07-05 1987-05-26 E.I. Du Pont De Nemours And Company Substituted benzoate ester prodrug derivatives of 3-hydroxymorphinans, which are analgesics or narcotic antagonists
EP0615756B1 (de) * 1993-03-15 2001-06-27 National Science Council Nalbuphinester und diese enthaltende Arzneimittel mit verzögerter Wirkstoffabgabe

Also Published As

Publication number Publication date
EP1149836B1 (de) 2003-02-26
DE60001487D1 (de) 2003-04-03
ES2188481T3 (es) 2003-07-01
DE60001487T2 (de) 2003-12-24
EP1149836A1 (de) 2001-10-31

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Legal Events

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