|
US6379971B1
(en)
|
1998-02-24 |
2002-04-30 |
Target Discovery, Inc. |
Methods for sequencing proteins
|
|
AU755334C
(en)
*
|
1998-08-25 |
2004-02-26 |
University Of Washington |
Rapid quantitative analysis of proteins or protein function in complex mixtures
|
|
CA2361384A1
(en)
*
|
1999-02-11 |
2000-08-17 |
Sun Ai Raillard |
High throughput mass spectrometry
|
|
US6629040B1
(en)
|
1999-03-19 |
2003-09-30 |
University Of Washington |
Isotope distribution encoded tags for protein identification
|
|
CA2369868A1
(en)
*
|
1999-04-15 |
2000-10-26 |
The University Of Virginia Patent Foundation |
Proteome mining
|
|
US6716636B1
(en)
|
1999-04-20 |
2004-04-06 |
Target Discovery, Inc. |
Methods for sequencing proteins
|
|
US6764817B1
(en)
|
1999-04-20 |
2004-07-20 |
Target Discovery, Inc. |
Methods for conducting metabolic analyses
|
|
US6937330B2
(en)
|
1999-04-23 |
2005-08-30 |
Ppd Biomarker Discovery Sciences, Llc |
Disposable optical cuvette cartridge with low fluorescence material
|
|
EP1179175A2
(en)
*
|
1999-05-14 |
2002-02-13 |
Karolinska Innovations AB |
Materials and methods relating to disease diagnosis
|
|
US6960439B2
(en)
|
1999-06-28 |
2005-11-01 |
Source Precision Medicine, Inc. |
Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
|
|
US6692916B2
(en)
|
1999-06-28 |
2004-02-17 |
Source Precision Medicine, Inc. |
Systems and methods for characterizing a biological condition or agent using precision gene expression profiles
|
|
US6687395B1
(en)
*
|
1999-07-21 |
2004-02-03 |
Surromed, Inc. |
System for microvolume laser scanning cytometry
|
|
US6783929B1
(en)
|
1999-11-02 |
2004-08-31 |
Chiron Corporation |
Biological sample component purification and differential display
|
|
ATE340025T1
(de)
*
|
2000-01-06 |
2006-10-15 |
Caliper Life Sciences Inc |
Vorrichtungen und verfahren für hochdurchsatz- probenentnahme und analyse
|
|
AU2001227280A1
(en)
|
2000-04-10 |
2001-10-23 |
The Scripps Research Institute |
Proteomic analysis using activity-based probe libraries
|
|
DE10021737C2
(de)
*
|
2000-05-04 |
2002-10-17 |
Hermann Haller |
Verfahren und Vorrichtung zur qualitativen und/oder quantitativen Bestimmung eines Protein- und/oder Peptidmusters einer Flüssigkeitsprobe, die dem menschlichen oder tierischen Körper entnommen wird
|
|
ATE344456T1
(de)
*
|
2000-05-05 |
2006-11-15 |
Purdue Research Foundation |
Durch affinität ausgewählte unterschriftspeptide zur identifizierung und quantifizierung von proteinen
|
|
US7153682B2
(en)
|
2000-06-05 |
2006-12-26 |
Chiron Corporation |
Microarrays on mirrored substrates for performing proteomic analyses
|
|
US7148058B2
(en)
|
2000-06-05 |
2006-12-12 |
Chiron Corporation |
Protein microarrays on mirrored surfaces for performing proteomic analyses
|
|
DE10027794A1
(de)
*
|
2000-06-07 |
2001-12-13 |
Basf Ag |
Verfahren zur Analyse Enzym-katalysierter Umsetzungen mit MALDI-TOF-Massenspektrometrie
|
|
AU2001269058A1
(en)
*
|
2000-06-07 |
2001-12-17 |
Basf Aktiengesellschaft |
Method for the qualitative and quantitative analysis of complex mixtures of chemical compounds, using maldi-tof mass spectrometry
|
|
CA2411126A1
(en)
|
2000-06-09 |
2001-12-13 |
Mds Proteomics, Inc. |
Labeling of proteomic samples during proteolysis for quantitation and sample multiplexing
|
|
AU2001266894B2
(en)
|
2000-06-12 |
2006-03-16 |
University Of Washington |
Selective labeling and isolation of phosphopeptides and applications to proteomeanalysis
|
|
US7567870B1
(en)
|
2000-07-31 |
2009-07-28 |
Institute For Systems Biology |
Multiparameter analysis for predictive medicine
|
|
EP1350106A2
(en)
*
|
2000-08-11 |
2003-10-08 |
Agilix Corporation |
Ultra-sensitive detection systems
|
|
EP1332513A2
(en)
*
|
2000-08-25 |
2003-08-06 |
Genencor International, Inc. |
Detecting polymers and polymer fragments
|
|
DE10043470B4
(de)
*
|
2000-09-04 |
2006-01-19 |
Mpb Meltec Patent- Und Beteiligungsgesellschaft Mbh |
Verfahren zur Identifizierung von zellspezifischen Proteinen
|
|
WO2002029032A2
(en)
*
|
2000-09-30 |
2002-04-11 |
Diversa Corporation |
Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating
|
|
SE0003566D0
(sv)
*
|
2000-10-02 |
2000-10-02 |
Amersham Pharm Biotech Ab |
A method for the quantitative determination of one or more compounds
|
|
EP1325322A2
(en)
*
|
2000-10-03 |
2003-07-09 |
Dionex Corporation |
Method and system for peak parking in liquid chromatography-mass spectrometer (lc-ms) analysis
|
|
US20040209251A1
(en)
|
2000-10-19 |
2004-10-21 |
Schneider Luke V |
Methods for determining protein and peptide terminal sequences
|
|
EP1330654B1
(en)
|
2000-10-23 |
2006-03-08 |
Genetics Institute, LLC |
Acid-labile isotope-coded extractant (alice) in mass spectometric analysis
|
|
AU4173202A
(en)
|
2000-10-23 |
2002-06-18 |
Inst Genetics Llc |
Isotope-coded ionization-enhancing reagents (icier) for high-throughput protein identification and quantitation using matrix-assisted laser desorption ionization mass spectrometry
|
|
WO2002042427A2
(en)
*
|
2000-10-25 |
2002-05-30 |
Surromed, Inc. |
Mass tags for quantitative analysis
|
|
SE0004094D0
(sv)
*
|
2000-11-09 |
2000-11-09 |
Amersham Pharm Biotech Ab |
A method for the quantification of carbohudrates
|
|
US6787761B2
(en)
*
|
2000-11-27 |
2004-09-07 |
Surromed, Inc. |
Median filter for liquid chromatography-mass spectrometry data
|
|
US20020095260A1
(en)
*
|
2000-11-28 |
2002-07-18 |
Surromed, Inc. |
Methods for efficiently mining broad data sets for biological markers
|
|
US6797523B2
(en)
*
|
2000-11-30 |
2004-09-28 |
Affinium Pharmaceuticals, Inc. |
Methods for systematic identification of protein—protein interactions
|
|
US20020090652A1
(en)
*
|
2000-12-22 |
2002-07-11 |
Fu Emil Wei-Ming |
Inverse labeling method for the rapid identification of marker/target proteins
|
|
US20020115056A1
(en)
|
2000-12-26 |
2002-08-22 |
Goodlett David R. |
Rapid and quantitative proteome analysis and related methods
|
|
WO2002055989A2
(en)
*
|
2001-01-12 |
2002-07-18 |
The Regents Of The University Of California |
Stable isotope, site-specific mass tagging for protein identification
|
|
US7166436B2
(en)
|
2001-01-26 |
2007-01-23 |
Syngenta Participations, Ag |
Differential labeling for quantitative analysis of complex protein mixtures
|
|
US6969757B2
(en)
|
2001-01-26 |
2005-11-29 |
Syngenta Participations Ag |
Differential labeling for quantitative analysis of complex protein mixtures
|
|
WO2002063271A2
(en)
*
|
2001-02-05 |
2002-08-15 |
Activx Biosciences, Inc. |
Activity based probe analysis
|
|
US6818454B2
(en)
|
2001-02-16 |
2004-11-16 |
Battelle Memorial Institute |
Phosphoprotein binding agents and methods of their use
|
|
DE60237194D1
(de)
|
2001-03-02 |
2010-09-16 |
Activx Biosciences Inc |
Plattform für protein-profiling
|
|
WO2002077016A2
(en)
*
|
2001-03-22 |
2002-10-03 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Methods and apparatus for gel-free qualitative and quantitative proteome analysis, and uses therefore
|
|
EP1383920B1
(en)
*
|
2001-04-03 |
2010-09-29 |
Thermo Finnigan Llc |
Methods and kits useful for the simplification of complex peptide mixtures
|
|
CN1463291A
(zh)
*
|
2001-04-19 |
2003-12-24 |
赛弗根生物系统股份有限公司 |
用质谱法和亲和标记物鉴定生物分子的特性
|
|
US7045296B2
(en)
*
|
2001-05-08 |
2006-05-16 |
Applera Corporation |
Process for analyzing protein samples
|
|
US7183116B2
(en)
|
2001-05-14 |
2007-02-27 |
The Institute For Systems Biology |
Methods for isolation and labeling of sample molecules
|
|
JP2005502030A
(ja)
*
|
2001-05-29 |
2005-01-20 |
リージェンツ オブ ザ ユニバーシティ オブ ミシガン |
タンパク質解析のシステムおよび方法
|
|
CA2349265A1
(en)
*
|
2001-05-30 |
2002-11-30 |
Andrew Emili |
Protein expression profile database
|
|
CA2453725A1
(en)
*
|
2001-07-13 |
2003-01-23 |
Syngenta Participations Ag |
System and method of determining proteomic differences
|
|
US6800449B1
(en)
|
2001-07-13 |
2004-10-05 |
Syngenta Participations Ag |
High throughput functional proteomics
|
|
AU2002322506A1
(en)
*
|
2001-07-16 |
2003-03-03 |
President And Fellows Of Harvard College |
Non-affinity based isotope tagged peptides and methods for using the same
|
|
EP2053406A3
(en)
|
2001-07-16 |
2009-06-24 |
caprotec bioanalytics GmbH |
Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
|
|
US7343247B2
(en)
|
2001-07-30 |
2008-03-11 |
The Institute For Systems Biology |
Methods of classifying drug responsiveness using multiparameter analysis
|
|
WO2003016861A2
(en)
*
|
2001-08-14 |
2003-02-27 |
President And Fellows Of Harvard College |
Absolute quantification of proteins and modified forms thereof by multistage mass spectrometry
|
|
US6873915B2
(en)
*
|
2001-08-24 |
2005-03-29 |
Surromed, Inc. |
Peak selection in multidimensional data
|
|
AU2002341862C1
(en)
*
|
2001-09-27 |
2009-01-29 |
Purdue Research Foundation |
Controlling isotope effects during fractionation of analytes
|
|
US20030078739A1
(en)
*
|
2001-10-05 |
2003-04-24 |
Surromed, Inc. |
Feature list extraction from data sets such as spectra
|
|
US6756586B2
(en)
|
2001-10-15 |
2004-06-29 |
Vanderbilt University |
Methods and apparatus for analyzing biological samples by mass spectrometry
|
|
DE10153631B4
(de)
*
|
2001-10-31 |
2006-04-13 |
Lottspeich, Friedrich, Dr. |
Verfahren zum Vergleich zweier Proteinzustände
|
|
US7132295B2
(en)
|
2001-11-09 |
2006-11-07 |
Bayer Aktiengesellschaft |
Isotopically coded affinity markers 3
|
|
KR20040064275A
(ko)
|
2001-11-09 |
2004-07-16 |
소스 프리시전 메디슨, 인코포레이티드 |
유전자 발현 프로파일을 이용한 질병의 동정, 모니터링,치료 및 생물학적 상태의 확인
|
|
CA2466356A1
(en)
*
|
2001-11-09 |
2003-05-15 |
Bayer Healthcare Ag |
Isotopically coded affinity marker 2
|
|
DE10154744A1
(de)
*
|
2001-11-09 |
2003-05-22 |
Bayer Ag |
Isotopencodierte Affinitätsmarker
|
|
WO2003042774A2
(en)
*
|
2001-11-13 |
2003-05-22 |
Caprion Pharmaceuticals Inc. |
Mass intensity profiling system and uses thereof
|
|
US20030091976A1
(en)
*
|
2001-11-14 |
2003-05-15 |
Ciphergen Biosystems, Inc. |
Methods for monitoring polypeptide production and purification using surface enhanced laser desorption/ionization mass spectrometry
|
|
DE10158860B4
(de)
|
2001-11-30 |
2007-04-05 |
Bruker Daltonik Gmbh |
Massenspektrometrische Proteingemischanalyse
|
|
EP1319954A1
(en)
*
|
2001-12-12 |
2003-06-18 |
Centre National de Genotypage |
Methods for protein analysis using protein capture arrays
|
|
US7623969B2
(en)
|
2002-01-31 |
2009-11-24 |
The Institute For Systems Biology |
Gene discovery for the system assignment of gene function
|
|
EP1483399B1
(en)
*
|
2002-02-12 |
2008-10-29 |
The Regents of the University of California |
Measurement of biosynthesis and breakdown rates of biological molecules that are inaccessible or not easily accessible to direct sampling, non-invasively, by label incorporation into metabolic derivatives and catabolitic products
|
|
CA2475011C
(en)
*
|
2002-02-14 |
2015-07-07 |
Ajinomoto Co., Inc. |
Method for analysis of compounds with amino group and analytical reagent therefor
|
|
DK1502102T3
(da)
*
|
2002-03-11 |
2009-05-04 |
Caprotec Bioanalytics Gmbh |
Forbindelser og fremgangsmåder til analysering af proteomet
|
|
US7288382B2
(en)
|
2002-03-14 |
2007-10-30 |
The Board Of Trustees Od The Leland Stanford Junior University |
Methods for structural analysis of proteins
|
|
KR20040094856A
(ko)
*
|
2002-03-25 |
2004-11-10 |
데이진 가부시키가이샤 |
생체 시료내 보효소 a 류의 측정방법
|
|
WO2003087834A2
(en)
*
|
2002-04-08 |
2003-10-23 |
Affinium Pharmaceuticals, Inc. |
High throughput analysis of recombinant proteins in multi-well plates
|
|
US6989100B2
(en)
*
|
2002-05-09 |
2006-01-24 |
Ppd Biomarker Discovery Sciences, Llc |
Methods for time-alignment of liquid chromatography-mass spectrometry data
|
|
AU2003261074A1
(en)
*
|
2002-05-20 |
2003-12-02 |
Jason M. Hogan |
Protein identification from protein product ion spectra
|
|
US20040229294A1
(en)
|
2002-05-21 |
2004-11-18 |
Po-Ying Chan-Hui |
ErbB surface receptor complexes as biomarkers
|
|
US7052916B2
(en)
*
|
2002-05-24 |
2006-05-30 |
Immunex Corporation |
Polypeptide analyses using stable isotope labeling
|
|
GB0212522D0
(en)
*
|
2002-05-31 |
2002-07-10 |
Shimadzu Res Lab Europe Ltd |
Selective binding and analysis of macromolecules
|
|
EP1514107B1
(en)
|
2002-06-03 |
2013-05-15 |
The Institute for Systems Biology |
Methods for quantitative proteome analysis of glycoproteins
|
|
AU2003259029A1
(en)
|
2002-06-04 |
2003-12-19 |
The Institute For Systems Biology |
Methods for high throughput and quantitative proteome analysis
|
|
JP2005529335A
(ja)
*
|
2002-06-10 |
2005-09-29 |
フィネクサス, インク. |
開放チャンネルを使って生体分子を固体相として抽出するシステムと方法
|
|
DE10227599B4
(de)
*
|
2002-06-20 |
2005-04-28 |
Proteome Factory Ag |
Verfahren und Reagenz zur spezifischen Identifizierung und Quantifizierung von einem oder mehreren Proteinen in einer Probe
|
|
AU2003236369A1
(en)
*
|
2002-06-28 |
2004-01-19 |
Shimadzu Corporation |
Sulfenyl compound, labeling reagent, and method of analyzing peptide
|
|
AU2003252593A1
(en)
|
2002-07-10 |
2004-02-02 |
Seikagaku Corporation |
Sulfotransferase inhibitors
|
|
CA2393726A1
(en)
*
|
2002-07-16 |
2004-01-16 |
Steven J. Locke |
Quantitative proteomics via isotopically differentiated derivatization
|
|
GB0305796D0
(en)
|
2002-07-24 |
2003-04-16 |
Micromass Ltd |
Method of mass spectrometry and a mass spectrometer
|
|
US7409296B2
(en)
*
|
2002-07-29 |
2008-08-05 |
Geneva Bioinformatics (Genebio), S.A. |
System and method for scoring peptide matches
|
|
AU2003256819B2
(en)
*
|
2002-07-30 |
2009-11-12 |
The Regents Of The University Of California |
Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome using mass spectrometry
|
|
US7501286B2
(en)
|
2002-08-14 |
2009-03-10 |
President And Fellows Of Harvard College |
Absolute quantification of proteins and modified forms thereof by multistage mass spectrometry
|
|
US7473535B2
(en)
|
2002-08-20 |
2009-01-06 |
The Institute For Systems Biology |
Chemical reagents and methods for detection and quantification of proteins in complex mixtures
|
|
JP4395439B2
(ja)
*
|
2002-09-12 |
2010-01-06 |
フラームス・インテルウニフェルシタイル・インステイチュート・フォール・ビオテヒノロヒー・ヴェーゼットウェー(ヴェーイーベー・ヴェーゼットウェー) |
薬物標的の同定のための方法
|
|
EP1546359A4
(en)
|
2002-09-12 |
2007-05-09 |
Molecular Probes Inc |
JOB-SPECIFIC MARKING OF AFFINITY DAYS IN FUSION PROTEINS
|
|
WO2004036189A2
(en)
|
2002-10-18 |
2004-04-29 |
Promega Corporation |
Methods for separating molecules
|
|
US6944549B2
(en)
*
|
2002-10-25 |
2005-09-13 |
Syngenta Participations Ag |
Method and apparatus for automated detection of peaks in spectroscopic data
|
|
EP2595173B1
(en)
|
2002-10-29 |
2016-09-14 |
Target Discovery, Inc. |
Method for increasing ionization efficiency in mass spectroscopy
|
|
US7846748B2
(en)
|
2002-12-02 |
2010-12-07 |
The University Of North Carolina At Chapel Hill |
Methods of quantitation and identification of peptides and proteins
|
|
US7425451B2
(en)
|
2002-12-13 |
2008-09-16 |
Agilent Technologies, Inc. |
Triazine derivatives as universal peptide isotope tag reagents (U-PIT)
|
|
US7109040B2
(en)
*
|
2002-12-13 |
2006-09-19 |
Agilent Technologies, Inc. |
Modular isotope coding approach to proteomic analysis
|
|
US20060105343A1
(en)
*
|
2003-01-09 |
2006-05-18 |
Children's Medical Center Corporation |
Methods for diagnosis and prognosis of cancer
|
|
US7422865B2
(en)
*
|
2003-01-13 |
2008-09-09 |
Agilent Technologies, Inc. |
Method of identifying peptides in a proteomic sample
|
|
EP1583972B1
(en)
*
|
2003-01-16 |
2010-11-24 |
caprotec bioanalytics GmbH |
Methods for identifying drug non-target proteins
|
|
US20040219685A1
(en)
|
2003-01-30 |
2004-11-04 |
Applera Corporation |
Methods and mixtures pertaining to analyte determination using electrophilic labeling reagents
|
|
WO2004079370A1
(en)
*
|
2003-03-03 |
2004-09-16 |
Universiteit Leiden |
Analysis of the proteome of a living cell by labelling the proteins in the intact cell
|
|
TW200508606A
(en)
*
|
2003-03-07 |
2005-03-01 |
Nard Kenkyusho Kk |
Method of finding molecular weight of phosphoric acid monoester compound, and additive for mass spectrometric measurement
|
|
CA2521130C
(en)
|
2003-04-01 |
2013-05-14 |
Activx Biosciences, Inc. |
Acyl-phosphate and phosphonate probes and methods of their synthesis and use in proteomic analysis
|
|
WO2004097372A2
(en)
|
2003-04-28 |
2004-11-11 |
The Regents Of The University Of California |
Element-coded affinity tags
|
|
US7267994B2
(en)
|
2003-04-28 |
2007-09-11 |
Regents Of The University Of California |
Element-coded affinity tags
|
|
GB0311961D0
(en)
|
2003-05-23 |
2003-06-25 |
Health Prot Agency |
Mass-based toxin assay and substrates therefor
|
|
EP1631553A4
(en)
*
|
2003-06-06 |
2008-09-10 |
Harvard College |
PEPTIDES BASED ON CAPTURE AND RELEASE BASED ISOTOPES AND METHODS OF USING PEPTIDES
|
|
CA2529863A1
(en)
*
|
2003-06-17 |
2004-12-23 |
Vib Vzw |
Peptide combos and their uses
|
|
GB0314209D0
(en)
*
|
2003-06-19 |
2003-07-23 |
Amersham Biosciences Ab |
Novel MS reagents
|
|
WO2005007677A2
(en)
|
2003-07-10 |
2005-01-27 |
The Institute For Systems Biology |
Affinity capture of peptides by microarray and related methods
|
|
FR2857451B1
(fr)
*
|
2003-07-11 |
2005-09-30 |
Commissariat Energie Atomique |
Procede et dispositif pour l'analyse de milieux reactionnels vivants
|
|
CA2535510C
(en)
*
|
2003-08-11 |
2013-10-15 |
Monogram Biosciences, Inc. |
Detecting and profiling molecular complexes
|
|
US20050048499A1
(en)
*
|
2003-08-29 |
2005-03-03 |
Perkin Elmer Life Sciences, Inc. |
Tandem mass spectrometry method for the genetic screening of inborn errors of metabolism in newborns
|
|
WO2005022156A1
(ja)
*
|
2003-08-29 |
2005-03-10 |
Reverse Proteomics Research Institute Co., Ltd. |
タンパク質の固定化方法
|
|
US7485435B2
(en)
*
|
2004-08-30 |
2009-02-03 |
Perkinelmer Las, Inc. |
Simultaneous detection of metabolic enzyme activity and metabolite levels
|
|
US20050074895A1
(en)
*
|
2003-09-05 |
2005-04-07 |
Bio-Rad Laboratories, Inc. |
Alkyl-substituted vinyl pyridines for mass-coded tagging of proteins
|
|
US7081623B2
(en)
|
2003-09-05 |
2006-07-25 |
Lucent Technologies Inc. |
Wafer-based ion traps
|
|
WO2005031304A2
(en)
*
|
2003-09-22 |
2005-04-07 |
Becton, Dickinson And Company |
Quantification of analytes using internal standards
|
|
US7145019B2
(en)
*
|
2003-10-16 |
2006-12-05 |
Ambergen, Inc. |
Photocleavable isotope-coded affinity tags
|
|
US7348416B2
(en)
*
|
2003-11-21 |
2008-03-25 |
Applera Corporation |
Selective capture and enrichment of proteins expressed on the cell surface
|
|
EP1686372A4
(en)
*
|
2003-11-21 |
2009-04-01 |
Eisai R&D Man Co Ltd |
QUANTIFICATION METHOD USING AN ISOTOPE-MARKED INTERNAL CALIBRATION, ANALYSIS SYSTEM FOR EXECUTING THE QUANTIFICATION METHOD AND ASSOCIATED SEPARATION PROGRAM
|
|
US20050202406A1
(en)
*
|
2003-11-25 |
2005-09-15 |
The Regents Of The University Of California |
Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systems
|
|
US20050148771A1
(en)
|
2004-01-05 |
2005-07-07 |
Applera Corporation. |
Active esters of N-substituted piperazine acetic acids, including isotopically enriched versions thereof
|
|
US7355045B2
(en)
|
2004-01-05 |
2008-04-08 |
Applera Corporation |
Isotopically enriched N-substituted piperazine acetic acids and methods for the preparation thereof
|
|
WO2005069891A2
(en)
*
|
2004-01-15 |
2005-08-04 |
Cedars-Sinai Medical Center |
System and method for expression proteomics based on isotope ratio modification
|
|
US20070087448A1
(en)
*
|
2004-02-16 |
2007-04-19 |
Nelsestuen Gary L |
Biological profiles and methods of use
|
|
TW200538738A
(en)
|
2004-02-20 |
2005-12-01 |
Univ California |
Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity
|
|
EP1731908B1
(en)
*
|
2004-03-31 |
2010-09-01 |
Kazuo Shinya |
Method of biosubstance trapping, structural analysis or/and identification with use of a labeling substance
|
|
US7248360B2
(en)
*
|
2004-04-02 |
2007-07-24 |
Ppd Biomarker Discovery Sciences, Llc |
Polychronic laser scanning system and method of use
|
|
JP4861308B2
(ja)
*
|
2004-04-07 |
2012-01-25 |
ジェネンテック, インコーポレイテッド |
抗体結合体の質量分析
|
|
US20080206737A1
(en)
*
|
2004-05-19 |
2008-08-28 |
Hunter Christie L |
Expression quantification using mass spectrometry
|
|
US20070054345A1
(en)
*
|
2004-05-19 |
2007-03-08 |
Hunter Christie L |
Expression quantification using mass spectrometry
|
|
EP1766413A2
(en)
*
|
2004-05-19 |
2007-03-28 |
Applera Corporation |
Expression quantification using mass spectrometry
|
|
DK1766412T3
(da)
|
2004-05-21 |
2009-05-25 |
Inst Systems Biology |
Sammensætninger og fremgangsmåder til kvantificering af serumglycoproteiner
|
|
US20080044857A1
(en)
*
|
2004-05-25 |
2008-02-21 |
The Gov Of Usa As Represented By The Secretary Of |
Methods For Making And Using Mass Tag Standards For Quantitative Proteomics
|
|
WO2005116629A1
(ja)
*
|
2004-05-26 |
2005-12-08 |
Ajinomoto Co., Inc. |
アミノ官能性化合物の分析方法及び装置
|
|
JP4317083B2
(ja)
|
2004-06-04 |
2009-08-19 |
株式会社日立ハイテクノロジーズ |
質量分析方法及び質量分析システム
|
|
WO2006091214A2
(en)
*
|
2004-06-18 |
2006-08-31 |
Molecular Probes, Inc. |
Fluorescent isotope tags and their method of use
|
|
CA2572754A1
(en)
*
|
2004-07-12 |
2006-02-16 |
Applera Corporation |
Mass tags for quantitative analyses
|
|
US20070048752A1
(en)
|
2004-07-12 |
2007-03-01 |
Applera Corporation |
Mass tags for quantitative analyses
|
|
US20060024757A1
(en)
|
2004-07-30 |
2006-02-02 |
Robert Hussa |
Detection of oncofetal fibronectin for selection of concepti
|
|
US7592139B2
(en)
*
|
2004-09-24 |
2009-09-22 |
Sandia National Laboratories |
High temperature flow-through device for rapid solubilization and analysis
|
|
JP4563764B2
(ja)
*
|
2004-10-01 |
2010-10-13 |
丸善製薬株式会社 |
ペプチドの定量方法
|
|
EP1814908A4
(en)
*
|
2004-11-22 |
2009-07-01 |
Biosight Ltd |
Activated labeling reagents and method for their preparation and use
|
|
US20060183238A1
(en)
|
2005-02-09 |
2006-08-17 |
Applera Corporation |
Amine-containing compound analysis methods
|
|
US20070037286A1
(en)
*
|
2005-02-09 |
2007-02-15 |
Subhasish Purkayastha |
Thyroxine-containing compound analysis methods
|
|
WO2006096704A2
(en)
|
2005-03-07 |
2006-09-14 |
Invitrogen Corporation |
Isotopically-labeled proteome standards
|
|
US20060251576A1
(en)
*
|
2005-05-03 |
2006-11-09 |
The Regents Of The University Of California |
Methods for measuring cholesterol metabolism and transport
|
|
US10687785B2
(en)
|
2005-05-12 |
2020-06-23 |
The Trustees Of Columbia Univeristy In The City Of New York |
System and method for electromechanical activation of arrhythmias
|
|
DE602005004902T2
(de)
*
|
2005-06-02 |
2008-10-16 |
Entelechon Gmbh |
Künstliches Protein, Verfahren für absolute Quantifizierung der Proteine und seine Benutzung
|
|
JP2006337176A
(ja)
*
|
2005-06-02 |
2006-12-14 |
Eisai R & D Management Co Ltd |
代謝物の定量方法
|
|
TW200711660A
(en)
*
|
2005-06-10 |
2007-04-01 |
Univ California |
Monitoring two dimensions of diabetes pathogenesis separately or concurrently (insulin sensitivity and beta-cell sufficiency): uses in diagnosis, prognosis, assessment of disease risk, and drug development
|
|
EP1754972A1
(en)
|
2005-08-17 |
2007-02-21 |
Agilent Technologies, Inc. |
Folded peptides containing metal binding pockets for protein tagging
|
|
JP5199101B2
(ja)
*
|
2005-10-13 |
2013-05-15 |
アプライド バイオシステムズ リミテッド ライアビリティー カンパニー |
生体分子の検定を開発するための方法
|
|
US7998717B2
(en)
|
2005-12-02 |
2011-08-16 |
Pacific Biosciences Of California, Inc. |
Mitigation of photodamage in analytical reactions
|
|
WO2007065273A1
(en)
*
|
2005-12-08 |
2007-06-14 |
The University Of British Columbia |
Mucopolysaccharidosis (mps) diagnostic methods, systems, kits and assays associated therewith
|
|
US20070140967A1
(en)
*
|
2005-12-19 |
2007-06-21 |
Wood Nichole L |
Agents and methods for analyzing protein interactions
|
|
US20070166810A1
(en)
*
|
2005-12-23 |
2007-07-19 |
Perkinelmer Las, Inc. |
Methods and compositions for detecting enzymatic activity
|
|
US20070148721A1
(en)
*
|
2005-12-28 |
2007-06-28 |
Agilent Technologies, Inc. |
Compositions, methods, systems, and kits for affinity purification
|
|
WO2007078229A1
(en)
*
|
2006-01-05 |
2007-07-12 |
Ge Healthcare Bio-Sciences Ab |
Kit and method for mass labelling
|
|
WO2008048345A2
(en)
*
|
2006-02-14 |
2008-04-24 |
Perkinelmer Las, Inc. |
Detection systems for mass labels
|
|
WO2008076139A1
(en)
|
2006-03-10 |
2008-06-26 |
Tethys Bioscience, Inc. |
Multiplex protein fractionation
|
|
EP1999270A4
(en)
*
|
2006-03-13 |
2010-04-28 |
Perkinelmer Las Inc |
SUBSTRATES AND INTERNAL STANDARDS FOR MASS SPECTROSCOPY DETECTION
|
|
US20090215098A1
(en)
*
|
2006-04-28 |
2009-08-27 |
Ucl Business Plc. |
Quantification of enzyme activity by mass spectrometry
|
|
US20100216657A1
(en)
*
|
2006-05-16 |
2010-08-26 |
Arcxis Biotechnologies, Inc. |
Pcr-free sample preparation and detection systems for high speed biologic analysis and identification
|
|
WO2008094205A2
(en)
*
|
2006-08-04 |
2008-08-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
A mild chemically cleavable linker system
|
|
US7879799B2
(en)
*
|
2006-08-10 |
2011-02-01 |
Institute For Systems Biology |
Methods for characterizing glycoproteins and generating antibodies for same
|
|
EP1916526A1
(en)
*
|
2006-10-26 |
2008-04-30 |
Koninklijke Philips Electronics N.V. |
Method for diagnostic and therapeutic target discovery by combining isotopic and isobaric labels
|
|
EP1921081A1
(en)
*
|
2006-11-06 |
2008-05-14 |
Koninklijke Philips Electronics N.V. |
Use of arylboronic acids in protein labelling
|
|
SI2436696T1
(sl)
|
2007-01-05 |
2017-10-30 |
University Of Zurich |
Anti-beta-amiloidno protitelo in načini njegove uporabe
|
|
KR100805777B1
(ko)
*
|
2007-02-22 |
2008-02-21 |
한국기초과학지원연구원 |
질량 스펙트럼 데이터 및 1차원 젤에서의 밴드 위치분석을 포함하는 단백질 수식화 분석 시스템 및 이를이용한 단백질 수식화 분석 방법
|
|
CA2690612C
(en)
|
2007-05-14 |
2016-07-05 |
Historx, Inc. |
Compartment segregation by pixel characterization using image data clustering
|
|
JP5003274B2
(ja)
*
|
2007-05-16 |
2012-08-15 |
株式会社日立製作所 |
質量分析システムおよび質量分析方法
|
|
WO2008150488A1
(en)
*
|
2007-06-01 |
2008-12-11 |
Laboratory Corporation Of America Holdings |
Methods and systems for quantification of peptides and other analytes
|
|
JP5593221B2
(ja)
|
2007-06-15 |
2014-09-17 |
ヒストロックス,インコーポレイテッド. |
顕微鏡機器を標準化するための方法およびシステム
|
|
JP4883540B2
(ja)
*
|
2007-06-21 |
2012-02-22 |
国立大学法人福井大学 |
同位体化合物を標識として使用するタンパク質の分析方法
|
|
EP2015076A1
(en)
*
|
2007-07-11 |
2009-01-14 |
Koninklijke Philips Electronics N.V. |
Protein labelling with tags comprising isotope-coded sub-tags and isobaric sub-tags
|
|
CA2604317C
(en)
|
2007-08-06 |
2017-02-28 |
Historx, Inc. |
Methods and system for validating sample images for quantitative immunoassays
|
|
CA2596204C
(en)
|
2007-08-07 |
2019-02-26 |
Historx, Inc. |
Method and system for determining an optimal dilution of a reagent
|
|
WO2009026252A1
(en)
*
|
2007-08-17 |
2009-02-26 |
University Of Washington |
Methods for assaying alpha-l-iduronidase enzymatic activity
|
|
US7978258B2
(en)
|
2007-08-31 |
2011-07-12 |
Historx, Inc. |
Automatic exposure time selection for imaging tissue
|
|
JP4921302B2
(ja)
*
|
2007-09-26 |
2012-04-25 |
株式会社日立ハイテクノロジーズ |
質量分析システム
|
|
US8604692B2
(en)
|
2007-11-06 |
2013-12-10 |
Translational Therapeutics, Inc. |
Mass spectrometry assay for eIF4E and eIF4E regulon activity
|
|
WO2009061904A2
(en)
*
|
2007-11-06 |
2009-05-14 |
Translational Therapeutics, Inc. |
MASS SPECTROMETRY ASSAY FOR eIF4E AND eIF4E REGULON ACTIVITY
|
|
US8334506B2
(en)
|
2007-12-10 |
2012-12-18 |
1St Detect Corporation |
End cap voltage control of ion traps
|
|
BRPI0906090A2
(pt)
*
|
2008-03-13 |
2016-05-03 |
Perkinelmar Las Inc |
substrato para análise de uma enzima, molécula e método para detectar atividade enzimática .
|
|
EP2108957A1
(en)
*
|
2008-04-07 |
2009-10-14 |
Koninklijke Philips Electronics N.V. |
Compounds and methods for the labelling and affinity-selection of proteins
|
|
US7973277B2
(en)
|
2008-05-27 |
2011-07-05 |
1St Detect Corporation |
Driving a mass spectrometer ion trap or mass filter
|
|
CA2725599A1
(en)
|
2008-05-30 |
2009-12-03 |
The University Of British Columbia |
Methods of diagnosing rejection of a kidney allograft using genomic or proteomic expression profiling
|
|
US20110151494A1
(en)
|
2008-06-30 |
2011-06-23 |
H. Lee Moffit Cancer & Research Institute |
Methods and materials for monitoring myeloma using quantitative mass spectrometry
|
|
US9240043B2
(en)
|
2008-09-16 |
2016-01-19 |
Novartis Ag |
Reproducible quantification of biomarker expression
|
|
US20100081924A1
(en)
*
|
2008-09-29 |
2010-04-01 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Histological facilitation systems and methods
|
|
US20100081915A1
(en)
*
|
2008-09-29 |
2010-04-01 |
Searete Llc, Alimited Liability Corporation Of The State Of Delaware |
Histological facilitation systems and methods
|
|
US20100081927A1
(en)
*
|
2008-09-29 |
2010-04-01 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Histological facilitation systems and methods
|
|
US20100081928A1
(en)
*
|
2008-09-29 |
2010-04-01 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Histological Facilitation systems and methods
|
|
US20100081916A1
(en)
*
|
2008-09-29 |
2010-04-01 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware. |
Histological facilitation systems and methods
|
|
US20100081926A1
(en)
*
|
2008-09-29 |
2010-04-01 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Histological facilitation systems and methods
|
|
US8673267B2
(en)
|
2009-03-02 |
2014-03-18 |
Massachusetts Institute Of Technology |
Methods and products for in vivo enzyme profiling
|
|
US8227251B2
(en)
*
|
2009-04-14 |
2012-07-24 |
Institute For Systems Biology |
Mass spectrum-based identification and quantitation of proteins and peptides
|
|
WO2010133173A1
(en)
*
|
2009-05-21 |
2010-11-25 |
Rongxiu Li |
Process for differential polypeptides detection and uses thereof
|
|
GB0916881D0
(en)
|
2009-09-25 |
2009-11-11 |
Electrophoretics Ltd |
Mass labels
|
|
EP2309262A1
(en)
|
2009-10-06 |
2011-04-13 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Method for quantifying biomolecules
|
|
WO2011075530A1
(en)
*
|
2009-12-15 |
2011-06-23 |
Dh Technologies Development Pte. Ltd. |
Analysis of amino acids and amine-containing compounds using tagging reagents and lc-ms workflow
|
|
AU2010340358B2
(en)
|
2009-12-21 |
2014-07-24 |
Pharmathene, Inc. |
Recombinant butyrylcholinesterases and truncates thereof
|
|
WO2011087869A1
(en)
*
|
2009-12-22 |
2011-07-21 |
Expression Pathology, Inc. |
Secreted protein acidic and rich in cysteine (sparc) protein srm/mrm assay
|
|
DK2517011T3
(en)
*
|
2009-12-22 |
2015-11-23 |
Expression Pathology Inc |
SRM / MRM analysis for the receptor protein for the insulin-like growth factor 1 (IGF-1R)
|
|
US9453845B2
(en)
|
2010-02-01 |
2016-09-27 |
Cell Signaling Technology, Inc. |
Mass spectroscopy analysis of mutant polypeptides in biological samples
|
|
DE102011017084B4
(de)
|
2010-04-14 |
2020-07-09 |
Wisconsin Alumni Research Foundation |
Massenspektrometriedaten-Erfassungsmodus zur Erzielung einer zuverlässigeren Proteinquantifizierung
|
|
WO2012003478A2
(en)
|
2010-07-02 |
2012-01-05 |
Ventana Medical Systems, Inc. |
Detecting targets using mass tags and mass spectrometry
|
|
WO2012021733A2
(en)
|
2010-08-12 |
2012-02-16 |
Pacific Biosciences Of California, Inc. |
Photodamage mitigation compounds and systems
|
|
US8742333B2
(en)
|
2010-09-17 |
2014-06-03 |
Wisconsin Alumni Research Foundation |
Method to perform beam-type collision-activated dissociation in the pre-existing ion injection pathway of a mass spectrometer
|
|
CN103547679A
(zh)
*
|
2010-11-24 |
2014-01-29 |
Dh科技发展私人贸易有限公司 |
葡萄糖-6-磷酸脱氢酶的高产量、灵敏检测
|
|
US8492163B2
(en)
|
2011-01-31 |
2013-07-23 |
Dh Technologies Development Pte. Ltd. |
Methods, mixtures, kits and compositions pertaining to analyte determination
|
|
ES2881535T3
(es)
|
2011-03-15 |
2021-11-29 |
Massachusetts Inst Technology |
Detección multiplexada con indicadores codificados con isótopos
|
|
DE102012102875B4
(de)
|
2011-04-04 |
2024-04-18 |
Wisconsin Alumni Research Foundation |
Vorläuferauswahl mit einem Artificial-Intelligence-Algorithmus erhöht Abdeckung und Reproduzierbarkeit von proteomischen Proben
|
|
US9659146B2
(en)
|
2011-05-02 |
2017-05-23 |
Tyler Stuart Bray |
Method for quantitative analysis of complex proteomic data
|
|
WO2012162664A1
(en)
|
2011-05-26 |
2012-11-29 |
The Trustees Of Columbia University In The City Of New York |
Systems and methods for opening of a tissue barrier in primates
|
|
WO2013036885A1
(en)
|
2011-09-08 |
2013-03-14 |
The Regents Of The University Of California |
Metabolic flux measurement, imaging and microscopy
|
|
EP2802670B1
(en)
|
2011-11-08 |
2019-12-25 |
University of Washington |
Lysosomal enzyme assay methods and compositions
|
|
EP2788772B1
(en)
|
2011-12-07 |
2018-02-14 |
GlaxoSmithKline LLC |
Methods for determining total body skeletal muscle mass
|
|
DE102013212179A1
(de)
*
|
2012-07-31 |
2014-02-06 |
Agilent Technologies, Inc. |
Derivatisierung von PNGase F-freigesetzter Glykane auf einem HPLC-Chip
|
|
RU2015126651A
(ru)
|
2012-12-10 |
2017-01-16 |
Фред Хатчинсон Кэнсер Рисёрч Сентер |
Способы скрининга
|
|
EP4414372A3
(en)
|
2013-03-15 |
2024-10-02 |
Perkinelmer Health Sciences Inc. |
Compounds and methods relating to testing for lysosomal storage disorders
|
|
US9134319B2
(en)
|
2013-03-15 |
2015-09-15 |
The Regents Of The University Of California |
Method for replacing biomarkers of protein kinetics from tissue samples by biomarkers of protein kinetics from body fluids after isotopic labeling in vivo
|
|
WO2014190234A1
(en)
|
2013-05-23 |
2014-11-27 |
Iphenotype Llc |
Method and system for maintaining or improving wellness
|
|
JP6847660B2
(ja)
|
2013-06-07 |
2021-03-24 |
マサチューセッツ インスティテュート オブ テクノロジー |
リガンドをコードする合成バイオマーカーのアフィニティベースの検出
|
|
CN109813914A
(zh)
*
|
2013-06-07 |
2019-05-28 |
皮尔斯生物科技有限公司 |
通过质谱分析用复用内标物对蛋白质和蛋白质修饰的绝对定量
|
|
JP6482577B2
(ja)
*
|
2014-12-29 |
2019-03-13 |
株式会社日立ハイテクノロジーズ |
分析方法、及び分析装置
|
|
EP3289107B1
(en)
|
2015-05-01 |
2024-12-11 |
The University of British Columbia |
Biomarkers for the detection of acute rejection in heart transplantation
|
|
WO2017040976A1
(en)
*
|
2015-09-02 |
2017-03-09 |
Erkki Ruoslahti |
Compounds and compositions for targeting brain injuries and methods of use thereof
|
|
CN105384785B
(zh)
*
|
2015-11-24 |
2018-06-19 |
中国人民解放军第二军医大学 |
含有半乳糖类脂肪酸衍生物的制备方法及其在医药领域的应用
|
|
AU2016380362B2
(en)
*
|
2015-12-31 |
2021-07-01 |
University Of Notre Dame Du Lac |
ESI-MS via an electrokinetically pumped interface
|
|
EP3405783B1
(en)
|
2016-01-22 |
2022-03-09 |
Purdue Research Foundation |
Charged mass labeling system
|
|
CN105911101B
(zh)
*
|
2016-04-08 |
2018-09-11 |
中南大学 |
一种简单灵敏的膜性能检测方法
|
|
WO2017177115A1
(en)
|
2016-04-08 |
2017-10-12 |
Massachusetts Institute Of Technology |
Methods to specifically profile protease activity at lymph nodes
|
|
WO2017193070A1
(en)
|
2016-05-05 |
2017-11-09 |
Massachusetts Institute Of Technology |
Methods and uses for remotely triggered protease activity measurements
|
|
JPWO2018003652A1
(ja)
*
|
2016-06-29 |
2019-05-16 |
株式会社日立ハイテクノロジーズ |
酵素反応及び質量分析方法に用いる化合物
|
|
US11339434B2
(en)
*
|
2016-07-29 |
2022-05-24 |
The Regents Of The University Of California |
Methods for determining gene functions
|
|
DE102017103600A1
(de)
*
|
2017-02-22 |
2018-08-23 |
Eberhard Karls Universität Tübingen Medizinische Fakultät |
Radioaktiv markiertes beta-Galactosidase Substrat für PET Bildgebung der Seneszenz
|
|
US11519905B2
(en)
|
2017-04-07 |
2022-12-06 |
Massachusetts Institute Of Technology |
Methods to spatially profile protease activity in tissue and sections
|
|
WO2018213331A1
(en)
*
|
2017-05-16 |
2018-11-22 |
Lankenau Institute For Medical Research |
Compositions comprising ligands to rhob protein and the uses thereof
|
|
CN107325154B
(zh)
*
|
2017-06-23 |
2020-11-20 |
广东华肽生物科技有限公司 |
一种具有改善记忆功效的多肽及其分离制备方法和用途
|
|
CN108169397B
(zh)
*
|
2017-11-30 |
2019-11-15 |
中国农业科学院北京畜牧兽医研究所 |
一种相对定量分析肉鸡谷胱甘肽s转移酶gsta2的方法
|
|
EP3739328A4
(en)
*
|
2018-01-09 |
2021-10-20 |
Shimadzu Corporation |
PROCESS FOR IDENTIFYING PROTEINS
|
|
WO2019173332A1
(en)
|
2018-03-05 |
2019-09-12 |
Massachusetts Institute Of Technology |
Inhalable nanosensors with volatile reporters and uses thereof
|
|
US10656059B2
(en)
|
2018-03-07 |
2020-05-19 |
Alcala Pharmaceutical, Inc. |
Method for qualitative and quantitative multiplexing of drug analytes from biological samples
|
|
RU2678090C1
(ru)
*
|
2018-05-28 |
2019-01-23 |
Федеральное государственное бюджетное научное учреждение "Федеральный научный центр пищевых систем им. В.М. Горбатова" РАН |
Способ подтверждения аутентичности вареных колбасных изделий
|
|
US12173349B2
(en)
|
2018-09-25 |
2024-12-24 |
Massachusetts Institute Of Technology |
Lung protease nanosensors and uses thereof
|
|
US11835522B2
(en)
|
2019-01-17 |
2023-12-05 |
Massachusetts Institute Of Technology |
Sensors for detecting and imaging of cancer metastasis
|
|
WO2020154541A1
(en)
*
|
2019-01-24 |
2020-07-30 |
The Board Of Trustees Of The Leland Stanford Junior University |
Compact hydroxamate-based affinity tags for artificially tagging biological macromolecules
|
|
CN110280229B
(zh)
*
|
2019-06-28 |
2022-03-11 |
东南大学 |
喋呤类化合物选择性分离富集材料制备与应用方法
|
|
CN115769056A
(zh)
*
|
2020-06-09 |
2023-03-07 |
里珍纳龙药品有限公司 |
用于定量抗体的高通量和基于质谱的方法
|
|
EP4229074A1
(en)
|
2020-10-16 |
2023-08-23 |
Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis |
Anti-tumor immunity induces the presentation of aberrant peptides
|
|
CN116829922A
(zh)
*
|
2020-12-17 |
2023-09-29 |
豪夫迈·罗氏有限公司 |
用于质谱法的基于蒸发的样品制备工作流程
|
|
CN113156002A
(zh)
*
|
2021-04-01 |
2021-07-23 |
河北利德检测技术有限公司 |
一种葡萄糖酸钙中5种有关物质的检测方法
|
|
WO2023080788A1
(en)
|
2021-11-05 |
2023-05-11 |
Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis |
Tryptophan depletion induces production and presentation of tryptophan to phenylalanine substitutions
|
|
WO2024238393A1
(en)
*
|
2023-05-10 |
2024-11-21 |
Northwestern University |
Proteoform imaging and characterization mass spectrometry
|