ATE430154T1 - Amino-substituierte cyclohexan derivate zur behandlung bakterieller infektionen - Google Patents

Amino-substituierte cyclohexan derivate zur behandlung bakterieller infektionen

Info

Publication number
ATE430154T1
ATE430154T1 AT03747857T AT03747857T ATE430154T1 AT E430154 T1 ATE430154 T1 AT E430154T1 AT 03747857 T AT03747857 T AT 03747857T AT 03747857 T AT03747857 T AT 03747857T AT E430154 T1 ATE430154 T1 AT E430154T1
Authority
AT
Austria
Prior art keywords
amino
treatment
bacterial infections
substituted cyclohexane
cyclohexane derivatives
Prior art date
Application number
AT03747857T
Other languages
German (de)
English (en)
Inventor
Jeffrey Axten
Robert Daines
David Davies
Timothy Gallagher
Graham Jones
William Miller
Neil Pearson
Israil Pendrak
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE430154T1 publication Critical patent/ATE430154T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT03747857T 2002-06-26 2003-06-25 Amino-substituierte cyclohexan derivate zur behandlung bakterieller infektionen ATE430154T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39170002P 2002-06-26 2002-06-26
US46096103P 2003-04-07 2003-04-07
PCT/EP2003/006756 WO2004002992A1 (en) 2002-06-26 2003-06-25 Compounds

Publications (1)

Publication Number Publication Date
ATE430154T1 true ATE430154T1 (de) 2009-05-15

Family

ID=30003201

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03747857T ATE430154T1 (de) 2002-06-26 2003-06-25 Amino-substituierte cyclohexan derivate zur behandlung bakterieller infektionen

Country Status (10)

Country Link
US (2) US7622481B2 (https=)
EP (1) EP1537123B1 (https=)
JP (1) JP4522262B2 (https=)
AR (1) AR040335A1 (https=)
AT (1) ATE430154T1 (https=)
AU (1) AU2003266949A1 (https=)
DE (1) DE60327438D1 (https=)
ES (1) ES2325831T3 (https=)
TW (1) TW200406413A (https=)
WO (1) WO2004002992A1 (https=)

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WO2010084152A1 (en) 2009-01-21 2010-07-29 Basilea Pharmaceutica Ag Novel bicyclic antibiotics
AR076222A1 (es) * 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
US8394858B2 (en) 2009-12-03 2013-03-12 Novartis Ag Cyclohexane derivatives and uses thereof
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TW201309689A (zh) 2011-02-07 2013-03-01 Daiichi Sankyo Co Ltd 含胺基之吡咯啶酮衍生物
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US9359275B2 (en) * 2012-02-23 2016-06-07 Children's Medical Center Corporation Natural product antibiotics and analogs thereof
KR20150138214A (ko) * 2013-03-29 2015-12-09 다이이찌 산쿄 가부시키가이샤 (1s,4s,5s)-4-브로모-6-옥사비시클로[3.2.1]옥탄-7-온의 제조 방법
CN103145709A (zh) * 2013-04-12 2013-06-12 苏州科捷生物医药有限公司 一种4-氯-1,6-萘啶的合成工艺
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WO2015193506A1 (en) * 2014-06-20 2015-12-23 Institut Pasteur Korea Anti-infective compounds
JP6546654B2 (ja) 2014-08-22 2019-07-17 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ 淋菌感染を治療するための三環式含窒素化合物
AR102256A1 (es) 2014-10-15 2017-02-15 Actelion Pharmaceuticals Ltd Derivados biaromáticos básicos antibacterianos con sustitución de aminoalcoxi
KR20200087273A (ko) 2014-10-24 2020-07-20 란도스 바이오파마, 인크. 란티오닌 합성효소 c-유사 2-계 치료제
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
WO2019032956A1 (en) 2017-08-10 2019-02-14 President And Fellows Of Harvard College LINCONSAMIDE ANTIBIOTICS AND USES THEREOF
EP3664799B1 (en) * 2017-08-10 2025-10-01 President And Fellows Of Harvard College Lincosamide antibiotics and uses thereof
BR112020010983A2 (pt) 2017-11-30 2020-11-17 Landos Biopharma, Inc método in vitro para gerar células preparadas a partir de células precursoras, células isoladas e método para tratar uma afecção em um animal com as células isoladas
CN108003100A (zh) * 2017-12-20 2018-05-08 北京六合宁远科技有限公司 一种药物中间体含氮杂环的胺类化合物的合成方法
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Also Published As

Publication number Publication date
ES2325831T3 (es) 2009-09-21
JP4522262B2 (ja) 2010-08-11
US20100081650A1 (en) 2010-04-01
EP1537123B1 (en) 2009-04-29
AU2003266949A1 (en) 2004-01-19
US20060189604A1 (en) 2006-08-24
DE60327438D1 (de) 2009-06-10
EP1537123A1 (en) 2005-06-08
JP2005539087A (ja) 2005-12-22
WO2004002992A1 (en) 2004-01-08
TW200406413A (en) 2004-05-01
AR040335A1 (es) 2005-03-30
US7622481B2 (en) 2009-11-24

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