DE60016047D1 - Dihydrobenzopyrane, dihydrobenzothiopyrane und tetrahydrochinoline zur behandlung cox-2-abhängiger krankheiten - Google Patents
Dihydrobenzopyrane, dihydrobenzothiopyrane und tetrahydrochinoline zur behandlung cox-2-abhängiger krankheitenInfo
- Publication number
- DE60016047D1 DE60016047D1 DE60016047T DE60016047T DE60016047D1 DE 60016047 D1 DE60016047 D1 DE 60016047D1 DE 60016047 T DE60016047 T DE 60016047T DE 60016047 T DE60016047 T DE 60016047T DE 60016047 D1 DE60016047 D1 DE 60016047D1
- Authority
- DE
- Germany
- Prior art keywords
- dihydrobenzothiopyrane
- dihydrobenzopyrane
- tetrahydrochinoline
- cox
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17428100P | 2000-01-03 | 2000-01-03 | |
US174281P | 2000-01-03 | ||
PCT/US2000/034525 WO2001049675A1 (en) | 2000-01-03 | 2000-12-19 | Dihydrobenzopyrans, dihydrobenzothiopyrans, and tetrahydroquinolines for the treatment of cox-2-mediated disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60016047D1 true DE60016047D1 (de) | 2004-12-23 |
DE60016047T2 DE60016047T2 (de) | 2005-11-03 |
Family
ID=22635573
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60016047T Expired - Fee Related DE60016047T2 (de) | 2000-01-03 | 2000-12-19 | Dihydrobenzopyrane, dihydrobenzothiopyrane und tetrahydrochinoline zur behandlung cox-2-abhängiger krankheiten |
Country Status (16)
Country | Link |
---|---|
US (2) | US6822102B2 (de) |
EP (1) | EP1274700B1 (de) |
JP (1) | JP2003519221A (de) |
AR (1) | AR026784A1 (de) |
AT (1) | ATE282604T1 (de) |
AU (1) | AU2584001A (de) |
CA (1) | CA2395795A1 (de) |
DE (1) | DE60016047T2 (de) |
EC (1) | ECSP013867A (de) |
ES (1) | ES2231301T3 (de) |
MX (1) | MXPA02006617A (de) |
PE (1) | PE20010995A1 (de) |
PT (1) | PT1274700E (de) |
TW (1) | TWI227234B (de) |
WO (1) | WO2001049675A1 (de) |
ZA (1) | ZA200205098B (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030100594A1 (en) * | 2001-08-10 | 2003-05-29 | Pharmacia Corporation | Carbonic anhydrase inhibitor |
CA2500582A1 (en) | 2002-10-04 | 2004-04-22 | Millennium Pharmaceuticals, Inc. | Pgd2 receptor antagonists for the treatment of inflammatory diseases |
US7504508B2 (en) | 2002-10-04 | 2009-03-17 | Millennium Pharmaceuticals, Inc. | PGD2 receptor antagonists for the treatment of inflammatory diseases |
US7299448B2 (en) | 2003-03-28 | 2007-11-20 | International Business Machines Corporation | Context-sensitive attributes |
GB0407908D0 (en) * | 2004-04-07 | 2004-05-12 | Univ York | Ionic liquids |
TW200603792A (en) * | 2004-04-23 | 2006-02-01 | Pharmacia & Upjohn Co Llc | Monotherapy for the treatment of psoriasis with cyclooxygenase-2 selective inhibitors |
US7122700B2 (en) | 2004-07-30 | 2006-10-17 | Xerox Corporation | Arylamine processes |
WO2006040672A1 (en) * | 2004-10-12 | 2006-04-20 | Pharmacia & Upjohn Company Llc | Substituted cyclopropyl chromene compounds for use in the treatment and prevention of inflammation related conditions |
ZA200707498B (en) | 2005-02-24 | 2008-11-26 | Millennium Pharm Inc | PGD2 receptor antagonists for the treatment of inflammatory diseases |
US7999107B2 (en) | 2007-01-31 | 2011-08-16 | Merck Sharp & Dohme Corp. | Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators |
BR112013000946B1 (pt) | 2010-07-14 | 2020-09-08 | Novartis Ag | Compostos heterocíclicos agonistas de receptor de ip, seus usos, composição e combinação farmacêuticas |
JP6073923B2 (ja) | 2012-01-13 | 2017-02-01 | ノバルティス アーゲー | 肺動脈高血圧症(pah)および関連障害の治療のためのip受容体アゴニストとしての縮合ピロール |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100343832B1 (ko) * | 1996-08-27 | 2002-07-20 | 시오노기세이야쿠가부시키가이샤 | 크로멘-3-카르복실산 유도체 |
DE19638484A1 (de) * | 1996-09-20 | 1998-03-26 | Basf Ag | Hetaroylderivate |
US6034256A (en) * | 1997-04-21 | 2000-03-07 | G.D. Searle & Co. | Substituted benzopyran derivatives for the treatment of inflammation |
US6077850A (en) * | 1997-04-21 | 2000-06-20 | G.D. Searle & Co. | Substituted benzopyran analogs for the treatment of inflammation |
-
2000
- 2000-12-19 PT PT00989326T patent/PT1274700E/pt unknown
- 2000-12-19 ES ES00989326T patent/ES2231301T3/es not_active Expired - Lifetime
- 2000-12-19 DE DE60016047T patent/DE60016047T2/de not_active Expired - Fee Related
- 2000-12-19 AT AT00989326T patent/ATE282604T1/de not_active IP Right Cessation
- 2000-12-19 MX MXPA02006617A patent/MXPA02006617A/es unknown
- 2000-12-19 EP EP00989326A patent/EP1274700B1/de not_active Expired - Lifetime
- 2000-12-19 WO PCT/US2000/034525 patent/WO2001049675A1/en active Search and Examination
- 2000-12-19 US US10/169,443 patent/US6822102B2/en not_active Expired - Fee Related
- 2000-12-19 AU AU25840/01A patent/AU2584001A/en not_active Abandoned
- 2000-12-19 CA CA002395795A patent/CA2395795A1/en not_active Abandoned
- 2000-12-19 JP JP2001550215A patent/JP2003519221A/ja not_active Withdrawn
- 2000-12-29 PE PE2000001413A patent/PE20010995A1/es not_active Application Discontinuation
-
2001
- 2001-01-03 AR ARP010100018A patent/AR026784A1/es not_active Application Discontinuation
- 2001-01-03 EC EC2001003867A patent/ECSP013867A/es unknown
- 2001-03-20 TW TW090100116A patent/TWI227234B/zh not_active IP Right Cessation
-
2002
- 2002-06-25 ZA ZA200205098A patent/ZA200205098B/xx unknown
-
2004
- 2004-08-02 US US10/909,589 patent/US20050010050A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE282604T1 (de) | 2004-12-15 |
ECSP013867A (es) | 2002-09-27 |
US20030232844A1 (en) | 2003-12-18 |
WO2001049675A1 (en) | 2001-07-12 |
JP2003519221A (ja) | 2003-06-17 |
US20050010050A1 (en) | 2005-01-13 |
AU2584001A (en) | 2001-07-16 |
US6822102B2 (en) | 2004-11-23 |
EP1274700A1 (de) | 2003-01-15 |
CA2395795A1 (en) | 2001-07-12 |
EP1274700B1 (de) | 2004-11-17 |
TWI227234B (en) | 2005-02-01 |
PE20010995A1 (es) | 2001-09-21 |
AR026784A1 (es) | 2003-02-26 |
PT1274700E (pt) | 2005-02-28 |
ES2231301T3 (es) | 2005-05-16 |
ZA200205098B (en) | 2004-03-31 |
MXPA02006617A (es) | 2004-09-10 |
DE60016047T2 (de) | 2005-11-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |