ATE282604T1 - Dihydrobenzopyrane, dihydrobenzothiopyrane und tetrahydrochinoline zur behandlung cox-2- abhängiger krankheiten - Google Patents
Dihydrobenzopyrane, dihydrobenzothiopyrane und tetrahydrochinoline zur behandlung cox-2- abhängiger krankheitenInfo
- Publication number
- ATE282604T1 ATE282604T1 AT00989326T AT00989326T ATE282604T1 AT E282604 T1 ATE282604 T1 AT E282604T1 AT 00989326 T AT00989326 T AT 00989326T AT 00989326 T AT00989326 T AT 00989326T AT E282604 T1 ATE282604 T1 AT E282604T1
- Authority
- AT
- Austria
- Prior art keywords
- tetrahydrocinolines
- dihydrobenzothiopyrans
- dihydrobenzopyrans
- cox
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Quinoline Compounds (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17428100P | 2000-01-03 | 2000-01-03 | |
PCT/US2000/034525 WO2001049675A1 (en) | 2000-01-03 | 2000-12-19 | Dihydrobenzopyrans, dihydrobenzothiopyrans, and tetrahydroquinolines for the treatment of cox-2-mediated disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE282604T1 true ATE282604T1 (de) | 2004-12-15 |
Family
ID=22635573
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00989326T ATE282604T1 (de) | 2000-01-03 | 2000-12-19 | Dihydrobenzopyrane, dihydrobenzothiopyrane und tetrahydrochinoline zur behandlung cox-2- abhängiger krankheiten |
Country Status (16)
Country | Link |
---|---|
US (2) | US6822102B2 (de) |
EP (1) | EP1274700B1 (de) |
JP (1) | JP2003519221A (de) |
AR (1) | AR026784A1 (de) |
AT (1) | ATE282604T1 (de) |
AU (1) | AU2584001A (de) |
CA (1) | CA2395795A1 (de) |
DE (1) | DE60016047T2 (de) |
EC (1) | ECSP013867A (de) |
ES (1) | ES2231301T3 (de) |
MX (1) | MXPA02006617A (de) |
PE (1) | PE20010995A1 (de) |
PT (1) | PT1274700E (de) |
TW (1) | TWI227234B (de) |
WO (1) | WO2001049675A1 (de) |
ZA (1) | ZA200205098B (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030100594A1 (en) * | 2001-08-10 | 2003-05-29 | Pharmacia Corporation | Carbonic anhydrase inhibitor |
US7504508B2 (en) | 2002-10-04 | 2009-03-17 | Millennium Pharmaceuticals, Inc. | PGD2 receptor antagonists for the treatment of inflammatory diseases |
BR0315041A (pt) | 2002-10-04 | 2005-08-16 | Millennium Pharm Inc | Métodos para inibir crth2 em um indivìduo que necessita inibição de crth2; composto; e composição farmacêutica |
US7299448B2 (en) | 2003-03-28 | 2007-11-20 | International Business Machines Corporation | Context-sensitive attributes |
GB0407908D0 (en) * | 2004-04-07 | 2004-05-12 | Univ York | Ionic liquids |
TW200603792A (en) * | 2004-04-23 | 2006-02-01 | Pharmacia & Upjohn Co Llc | Monotherapy for the treatment of psoriasis with cyclooxygenase-2 selective inhibitors |
US7122700B2 (en) | 2004-07-30 | 2006-10-17 | Xerox Corporation | Arylamine processes |
WO2006040672A1 (en) * | 2004-10-12 | 2006-04-20 | Pharmacia & Upjohn Company Llc | Substituted cyclopropyl chromene compounds for use in the treatment and prevention of inflammation related conditions |
MX2007010215A (es) | 2005-02-24 | 2007-11-07 | Millennium Pharm Inc | Antagonistas del receptor pgd2 para el tratamiento de enfermedades inflamatorias. |
US7999107B2 (en) | 2007-01-31 | 2011-08-16 | Merck Sharp & Dohme Corp. | Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators |
UA109786C2 (xx) | 2010-07-14 | 2015-10-12 | Гетероциклічні сполуки як агоністи ір-рецептора | |
EP2802589B1 (de) | 2012-01-13 | 2016-01-06 | Novartis AG | Annelierte pyrrole als ip-rezeptor-agonisten zur behandlung von pulmonaler arterieller hypertonie (pah) pah und verwandten erkrankungen |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3076066B2 (ja) * | 1996-08-27 | 2000-08-14 | 塩野義製薬株式会社 | クロメン−3−カルボン酸誘導体 |
DE19638484A1 (de) * | 1996-09-20 | 1998-03-26 | Basf Ag | Hetaroylderivate |
US6034256A (en) * | 1997-04-21 | 2000-03-07 | G.D. Searle & Co. | Substituted benzopyran derivatives for the treatment of inflammation |
US6077850A (en) * | 1997-04-21 | 2000-06-20 | G.D. Searle & Co. | Substituted benzopyran analogs for the treatment of inflammation |
-
2000
- 2000-12-19 JP JP2001550215A patent/JP2003519221A/ja not_active Withdrawn
- 2000-12-19 CA CA002395795A patent/CA2395795A1/en not_active Abandoned
- 2000-12-19 ES ES00989326T patent/ES2231301T3/es not_active Expired - Lifetime
- 2000-12-19 MX MXPA02006617A patent/MXPA02006617A/es unknown
- 2000-12-19 AU AU25840/01A patent/AU2584001A/en not_active Abandoned
- 2000-12-19 AT AT00989326T patent/ATE282604T1/de not_active IP Right Cessation
- 2000-12-19 EP EP00989326A patent/EP1274700B1/de not_active Expired - Lifetime
- 2000-12-19 PT PT00989326T patent/PT1274700E/pt unknown
- 2000-12-19 DE DE60016047T patent/DE60016047T2/de not_active Expired - Fee Related
- 2000-12-19 US US10/169,443 patent/US6822102B2/en not_active Expired - Fee Related
- 2000-12-19 WO PCT/US2000/034525 patent/WO2001049675A1/en active Search and Examination
- 2000-12-29 PE PE2000001413A patent/PE20010995A1/es not_active Application Discontinuation
-
2001
- 2001-01-03 AR ARP010100018A patent/AR026784A1/es not_active Application Discontinuation
- 2001-01-03 EC EC2001003867A patent/ECSP013867A/es unknown
- 2001-03-20 TW TW090100116A patent/TWI227234B/zh not_active IP Right Cessation
-
2002
- 2002-06-25 ZA ZA200205098A patent/ZA200205098B/xx unknown
-
2004
- 2004-08-02 US US10/909,589 patent/US20050010050A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20030232844A1 (en) | 2003-12-18 |
MXPA02006617A (es) | 2004-09-10 |
EP1274700A1 (de) | 2003-01-15 |
AR026784A1 (es) | 2003-02-26 |
EP1274700B1 (de) | 2004-11-17 |
DE60016047T2 (de) | 2005-11-03 |
DE60016047D1 (de) | 2004-12-23 |
ES2231301T3 (es) | 2005-05-16 |
CA2395795A1 (en) | 2001-07-12 |
PT1274700E (pt) | 2005-02-28 |
US6822102B2 (en) | 2004-11-23 |
PE20010995A1 (es) | 2001-09-21 |
US20050010050A1 (en) | 2005-01-13 |
ECSP013867A (es) | 2002-09-27 |
TWI227234B (en) | 2005-02-01 |
WO2001049675A1 (en) | 2001-07-12 |
AU2584001A (en) | 2001-07-16 |
JP2003519221A (ja) | 2003-06-17 |
ZA200205098B (en) | 2004-03-31 |
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Legal Events
Date | Code | Title | Description |
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UEP | Publication of translation of european patent specification |
Ref document number: 1274700 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |