ATE342738T1 - Kontrastmittel für diagnostische bildgebung mit verlängerter verweilzeit im blut - Google Patents

Kontrastmittel für diagnostische bildgebung mit verlängerter verweilzeit im blut

Info

Publication number
ATE342738T1
ATE342738T1 AT96902106T AT96902106T ATE342738T1 AT E342738 T1 ATE342738 T1 AT E342738T1 AT 96902106 T AT96902106 T AT 96902106T AT 96902106 T AT96902106 T AT 96902106T AT E342738 T1 ATE342738 T1 AT E342738T1
Authority
AT
Austria
Prior art keywords
blood
retention time
contrast agents
diagnostic imaging
extended retention
Prior art date
Application number
AT96902106T
Other languages
German (de)
English (en)
Inventor
Thomas J Mcmurry
Hironao Sajiki
Daniel M Scott
Randall B Lauffer
Original Assignee
Epix Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epix Pharm Inc filed Critical Epix Pharm Inc
Application granted granted Critical
Publication of ATE342738T1 publication Critical patent/ATE342738T1/de

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/101Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/103Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/101Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/091Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50Clinical applications
    • A61B6/507Clinical applications involving determination of haemodynamic parameters, e.g. perfusion CT
AT96902106T 1995-02-01 1996-01-16 Kontrastmittel für diagnostische bildgebung mit verlängerter verweilzeit im blut ATE342738T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38231795A 1995-02-01 1995-02-01

Publications (1)

Publication Number Publication Date
ATE342738T1 true ATE342738T1 (de) 2006-11-15

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AT96902106T ATE342738T1 (de) 1995-02-01 1996-01-16 Kontrastmittel für diagnostische bildgebung mit verlängerter verweilzeit im blut

Country Status (25)

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US (8) US6676929B2 (US20040208827A1-20041021-C00014.png)
EP (2) EP1716871A3 (US20040208827A1-20041021-C00014.png)
JP (4) JP4064458B2 (US20040208827A1-20041021-C00014.png)
KR (1) KR100403755B1 (US20040208827A1-20041021-C00014.png)
CN (3) CN1177806C (US20040208827A1-20041021-C00014.png)
AR (1) AR006510A1 (US20040208827A1-20041021-C00014.png)
AT (1) ATE342738T1 (US20040208827A1-20041021-C00014.png)
AU (1) AU689700B2 (US20040208827A1-20041021-C00014.png)
BR (1) BR9607136A (US20040208827A1-20041021-C00014.png)
CA (1) CA2211100C (US20040208827A1-20041021-C00014.png)
DE (3) DE69636635T2 (US20040208827A1-20041021-C00014.png)
DK (1) DK0806968T3 (US20040208827A1-20041021-C00014.png)
ES (1) ES2274523T3 (US20040208827A1-20041021-C00014.png)
FI (1) FI973183A0 (US20040208827A1-20041021-C00014.png)
HK (2) HK1002551A1 (US20040208827A1-20041021-C00014.png)
IL (1) IL116847A (US20040208827A1-20041021-C00014.png)
IS (1) IS2505B (US20040208827A1-20041021-C00014.png)
MY (1) MY128089A (US20040208827A1-20041021-C00014.png)
NL (1) NL300253I2 (US20040208827A1-20041021-C00014.png)
NO (2) NO326114B1 (US20040208827A1-20041021-C00014.png)
NZ (1) NZ301181A (US20040208827A1-20041021-C00014.png)
PT (1) PT806968E (US20040208827A1-20041021-C00014.png)
TW (1) TW319763B (US20040208827A1-20041021-C00014.png)
WO (1) WO1996023526A2 (US20040208827A1-20041021-C00014.png)
ZA (1) ZA96417B (US20040208827A1-20041021-C00014.png)

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US20070020185A1 (en) 2007-01-25
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