ATE246807T1 - Adduktabschirmungstest - Google Patents
AdduktabschirmungstestInfo
- Publication number
- ATE246807T1 ATE246807T1 AT96108880T AT96108880T ATE246807T1 AT E246807 T1 ATE246807 T1 AT E246807T1 AT 96108880 T AT96108880 T AT 96108880T AT 96108880 T AT96108880 T AT 96108880T AT E246807 T1 ATE246807 T1 AT E246807T1
- Authority
- AT
- Austria
- Prior art keywords
- signal
- label
- binding partner
- adduct
- alteration
- Prior art date
Links
- 239000012491 analyte Substances 0.000 abstract 3
- 230000004075 alteration Effects 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 2
- 239000003446 ligand Substances 0.000 abstract 2
- 230000035945 sensitivity Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/13—Tracers or tags
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/478,221 US5731148A (en) | 1995-06-07 | 1995-06-07 | Adduct protection assay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE246807T1 true ATE246807T1 (de) | 2003-08-15 |
Family
ID=23899023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96108880T ATE246807T1 (de) | 1995-06-07 | 1996-06-03 | Adduktabschirmungstest |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5731148A (de) |
| EP (1) | EP0747706B1 (de) |
| JP (1) | JP3577085B2 (de) |
| KR (1) | KR19990022460A (de) |
| AT (1) | ATE246807T1 (de) |
| AU (1) | AU703605B2 (de) |
| CA (1) | CA2222556C (de) |
| DE (1) | DE69629333T2 (de) |
| DK (1) | DK0747706T3 (de) |
| ES (1) | ES2203656T3 (de) |
| WO (1) | WO1996041197A1 (de) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5714380A (en) | 1986-10-23 | 1998-02-03 | Amoco Corporation | Closed vessel for isolating target molecules and for performing amplification |
| US7070925B1 (en) * | 1996-07-16 | 2006-07-04 | Gen-Probe Incorporated | Method for determining the presence of an RNA analyte in a sample using a modified oligonucleotide probe |
| US6130038A (en) * | 1996-07-16 | 2000-10-10 | Gen-Probe Incorporated | Method for amplifying target nucleic acids using modified primers |
| AU7019498A (en) | 1997-04-10 | 1998-10-30 | Diagnocure Inc. | Pca3, pca3 genes, and methods of use |
| EP0975807B1 (de) | 1997-05-02 | 2006-09-27 | Gen-Probe Incorporated | Zwei-schritt hybridisierung und einfang von einem polynukleotid |
| US6534273B2 (en) | 1997-05-02 | 2003-03-18 | Gen-Probe Incorporated | Two-step hybridization and capture of a polynucleotide |
| US6180340B1 (en) | 1997-10-31 | 2001-01-30 | Gen-Probe Incorporated | Extended dynamic range assays |
| WO1999049293A2 (en) | 1998-03-24 | 1999-09-30 | Boston Probes, Inc. | Methods, kits and compositions pertaining to detection complexes |
| WO2000001850A2 (en) * | 1998-07-02 | 2000-01-13 | Gen-Probe Incorporated | Molecular torches |
| US5998175A (en) * | 1998-07-24 | 1999-12-07 | Lumigen, Inc. | Methods of synthesizing and amplifying polynucleotides by ligation of multiple oligomers |
| AU776290B2 (en) | 1999-02-12 | 2004-09-02 | Gen-Probe Incorporated | Protection probes |
| US6623920B1 (en) | 1999-07-09 | 2003-09-23 | Gen-Probe Incorporated | Detection of HIV-1 by nucleic acid amplification |
| US6506887B1 (en) * | 1999-07-29 | 2003-01-14 | Somalogic, Incorporated | Conditional-selex |
| JP2003510075A (ja) | 1999-09-29 | 2003-03-18 | ディグノキュアー・インコーポレーテッド | 良性および悪性の前立腺組織におけるpca3メッセンジャーrna種 |
| US6506567B2 (en) * | 2000-01-31 | 2003-01-14 | Fuji Photo Film Co., Ltd. | Water-soluble flourescent intercalator compound |
| EP1252335A4 (de) * | 2000-02-03 | 2005-03-02 | Res Dev Foundation | SIGNALüBERMITTELNDE APTAMERE,WELCHE MOLEKULARE ERKENNUNG ZU EINEM DIFFERENTIELLEN SIGNAL üBERMITTELN |
| JP2004537263A (ja) * | 2000-12-14 | 2004-12-16 | ジェン−プローブ・インコーポレーテッド | ポリヌクレオチドの会合速度を増強するための方法およびキット |
| CA2434845C (en) | 2001-01-23 | 2013-11-19 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. | Hepatitis c virus replicons and replicon enhanced cells |
| US6780602B2 (en) | 2001-11-01 | 2004-08-24 | Microbiosystems, Limited Partnership | Taxonomic identification of pathogenic microorganisms and their toxic proteins |
| EP1513958B1 (de) | 2002-06-14 | 2011-08-10 | Gen-Probe Incorporated | Zusammensetzungen zum nachweis von hepatitis-b-virus |
| EP3241915B1 (de) | 2002-10-16 | 2021-06-23 | Gen-Probe Incorporated | Zusammensetzungen und verfahren zum nachweis des west-nil-viruses |
| WO2004070056A2 (en) | 2003-02-07 | 2004-08-19 | Diagnocure Inc. | Method to detect prostate cancer in a sample |
| US20060257929A1 (en) * | 2003-11-12 | 2006-11-16 | Microbiosystems, Limited Partnership | Method for the rapid taxonomic identification of pathogenic microorganisms and their toxic proteins |
| EP1694871B1 (de) | 2003-12-19 | 2010-08-25 | Gen-Probe Incorporated | Zusammensetzungen, verfahren und kits zum nachweis der nukleinsäuren von hiv-1 und hiv-2 |
| US8916503B2 (en) | 2004-02-18 | 2014-12-23 | Chromocell Corporation | Methods and materials using signaling probes |
| EP1745120A4 (de) | 2004-04-16 | 2010-04-14 | Spartan Bioscience Inc | System zur schnellen nukleinsäureamplifikation und -detektion |
| DK1778867T3 (da) | 2004-07-01 | 2010-08-02 | Gen Probe Inc | Fremgangsmåder og sammensætninger til detektering af nucleinsyrer i en biologisk prøve |
| EP2402465B1 (de) | 2004-07-13 | 2014-11-19 | Gen-Probe Incorporated | Verfahren und Kit zur Detektion von Hepatitis-A-Virus-Nukleinsäure |
| ES2759991T3 (es) | 2004-09-30 | 2020-05-12 | Gen Probe Inc | Ensayo para detectar y cuantificar el VIH-1 |
| US20060223080A1 (en) | 2004-11-09 | 2006-10-05 | Gen-Probe Incorporated | Compositions and methods for detecting group a streptococci |
| CA2491067A1 (en) | 2004-12-24 | 2006-06-24 | Stichting Katholieke Universiteit | Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer |
| ATE551433T1 (de) | 2005-05-06 | 2012-04-15 | Gen Probe Inc | Verfahren und produkte zum erfassen von nukleinsäurezielen |
| WO2006121773A2 (en) | 2005-05-06 | 2006-11-16 | Gen-Probe Incorporated | Compositions and assays to detect influenza virus a and b nucleic acids |
| EP2092056A1 (de) * | 2006-11-30 | 2009-08-26 | Chromocell Corporation | Optimierte wirtszellen zur proteinherstellung |
| EP1978111B1 (de) | 2007-04-02 | 2013-03-27 | Gen-Probe Incorporated | Zusammensetzungen, Kits und zugehörige Verfahren zur Erkennung und/oder Überwachung von Pseudomonas aeruginosa |
| WO2009002447A1 (en) | 2007-06-21 | 2008-12-31 | Gen-Probe Incorporated | Instrument and receptacles for use in performing processes |
| CA2721536A1 (en) | 2008-04-21 | 2009-10-29 | Gen-Probe Incorporated | Method for detecting chikungunya virus |
| US10316352B2 (en) * | 2008-05-13 | 2019-06-11 | Gen-Probe Incorporated | Methods of capturing a target nucleic acid for amplification and detection using an inactivatable target capture oligomer |
| AU2009262870B2 (en) | 2008-05-30 | 2014-03-20 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of Salmonella |
| US8097412B2 (en) * | 2008-07-12 | 2012-01-17 | Biodiagnostics, Inc. | DNA-based test for detection of annual and intermediate ryegrass |
| CA2638458A1 (en) * | 2008-07-31 | 2010-01-31 | Spartan Bioscience Inc. | Thermal recycling by positioning relative to fixed-temperature source |
| CN102292457B (zh) * | 2008-11-25 | 2014-04-09 | 简·探针公司 | 检测小rna的组合物和方法及其用途 |
| JP5793085B2 (ja) | 2008-12-30 | 2015-10-14 | ジェン−プローブ・インコーポレーテッド | Listeriaを検出およびモニターするための組成物、キットおよび関連する方法 |
| AU2010208085B2 (en) | 2009-01-30 | 2014-02-06 | Gen-Probe Incorporated | Systems and methods for detecting a signal and applying thermal energy to a signal transmission element |
| CA2756659A1 (en) | 2009-02-26 | 2010-09-02 | Gen-Probe Incorporated | Assay for detection of human parvovirus nucleic acid |
| EP2588629B1 (de) | 2010-06-30 | 2017-05-17 | Gen-Probe Incorporated | Methode und apparatur zur identifizierung von analyt-beinhaltenden proben unter verwendung von single-read determination des analyten und prozesskontrollsignalen |
| EP3305920B1 (de) | 2010-07-12 | 2020-02-12 | Gen-Probe Incorporated | Zusammensetzungen und assays zur erkennung von saisonaler h3-influenza a-virus-nukleinsäure |
| AU2011301804B2 (en) | 2010-09-16 | 2015-07-16 | Gen-Probe Incorporated | Capture probes immobilizable via L-nucleotide tail |
| EP2625297B1 (de) | 2010-10-04 | 2018-10-10 | Gen-Probe Prodesse, Inc. | Zusammensetzungen, verfahren und kits für den nachweis von adenovirus-nukleinsäuren |
| EP2732054B1 (de) | 2011-07-15 | 2019-04-03 | Gen-Probe Incorporated | Verfahren zum nachweis von menschlichen parvovirus nukleinsäuren in einem single-plex- oder multiplex-testverfahren |
| DE102011120550B4 (de) | 2011-12-05 | 2013-11-07 | Gen-Probe Prodesse, Inc. | Zusammensetzungen, Verfahren und Kits zur Detektion von Adenovirusnukleinsäuren |
| US20160123959A1 (en) | 2013-03-15 | 2016-05-05 | Chromocell Corporation | Methods and materials using signaling probes |
| CA2962956C (en) | 2014-10-20 | 2023-09-05 | Gen-Probe Incorporated | Red blood cell lysis solution |
| WO2017098321A1 (en) | 2015-12-11 | 2017-06-15 | Spartan Bioscience Inc. | Tube sealing system and methods for nucleic acid amplification |
| DE202017007129U1 (de) | 2016-04-27 | 2019-08-29 | Gen-Probe Incorporated | Lysereagenz für Blutzellen |
| EP3601619B1 (de) | 2017-03-24 | 2024-06-26 | Gen-Probe Incorporated | Zusammensetzungen und verfahren zum nachweis viraler pathogene in proben |
| CA3241799A1 (en) | 2017-03-24 | 2018-09-27 | Gen-Probe Incorporated | Compositions and methods for detecting or quantifying parainfluenza virus |
| US11384387B2 (en) | 2017-03-25 | 2022-07-12 | Gen-Probe Incorporated | Compositions, methods and kits to detect adenovirus nucleic acid |
| CA3155859A1 (en) | 2017-07-10 | 2019-01-17 | Gen-Probe Incorporated | Analytical systems and methods for nucleic acid amplification using sample assigning parameters |
| CN111094595A (zh) | 2017-08-11 | 2020-05-01 | 简·探针公司 | 用于检测金黄色葡萄球菌的组合物和方法 |
| US12110540B2 (en) | 2017-12-15 | 2024-10-08 | Gen-Probe Incorporated | Compositions and methods for detecting toxigenic Clostridium difficile |
| CA3089078A1 (en) | 2018-01-29 | 2019-08-01 | Gen-Probe Incorporated | Analytical systems and methods |
| US11453919B2 (en) | 2018-06-13 | 2022-09-27 | Gen-Probe Incorporated | Compositions and methods for detecting group B Streptococcus nucleic acid |
| EP3820616A1 (de) | 2018-07-10 | 2021-05-19 | Gen-Probe Incorporated | Verfahren und systeme zur detektion und quantifizierung von nukleinsäuren |
| EP3830302B1 (de) | 2018-08-01 | 2022-10-05 | Gen-Probe Incorporated | Zusammensetzungen und verfahren zum nachweis von nukleinsäuren des epstein-barr-virus |
| EP3841223A1 (de) | 2018-08-08 | 2021-06-30 | Gen-Probe Incorporated | Zusammensetzungen, verfahren und kits zum nachweis von mycoplasma genitalium |
| AU2019326462B2 (en) | 2018-08-21 | 2025-11-27 | Gen-Probe Incorporated | Compositions and methods for amplifying, detecting or quantifying human cytomegalovirus |
| AU2019350777B2 (en) | 2018-09-27 | 2025-11-27 | Gen-Probe Incorporated | Compositions and methods for detecting Bordetella pertussis and Bordetellaparapertussis nucleic acid |
| CA3112342A1 (en) | 2018-10-01 | 2020-04-09 | Gen-Probe Incorporated | Compositions and methods for amplifying or detecting varicella-zoster virus |
| US12054793B2 (en) | 2018-10-22 | 2024-08-06 | Gen-Probe Incorporated | Compositions and methods for amplifying, detecting or quantifying human polyomavirus BK virus |
| EP3942078A1 (de) | 2019-03-22 | 2022-01-26 | Gen-Probe Incorporated | Zusammensetzungen und verfahren zur detektion von gruppe-a-streptococcus |
| EP4371667A3 (de) | 2019-05-03 | 2024-07-31 | Gen-Probe Incorporated | Behältertransportsystem für ein analytisches system |
| JP7742830B2 (ja) | 2019-08-23 | 2025-09-22 | ジェン-プローブ・インコーポレーテッド | Treponema pallidumを検出するための組成物、方法、およびキット |
| AU2020343334A1 (en) | 2019-09-05 | 2022-04-07 | Gen-Probe Incorporated | Detection of Chlamydia trachomatis nucleic acid variants |
| EP4582563A3 (de) | 2020-03-04 | 2025-10-08 | Gen-Probe Incorporated | Zusammensetzungen und verfahren zum nachweis von sars-cov-2-nukleinsäure |
| WO2022087257A2 (en) | 2020-10-21 | 2022-04-28 | Gen-Probe Incorporated | Fluid container management system |
| EP4382620A3 (de) | 2021-07-27 | 2024-08-07 | Gen-Probe Incorporated | Zusammensetzungen und verfahren zum nachweis von c. jejuni und mindestens einer von salmonella, c. coli, shigella und stec. |
| CA3254118A1 (en) | 2022-03-15 | 2023-09-21 | Diagenode S.A. | DETECTION OF THE METHYLATION STATE OF A DNA SAMPLE |
| WO2024054924A1 (en) | 2022-09-08 | 2024-03-14 | Gen-Probe Incorporated | Method of detecting nucleic acid analytes using dual-specificity primers |
| EP4638804A2 (de) | 2022-12-19 | 2025-10-29 | Gen-Probe Incorporated | Zusammensetzungen und verfahren zum nachweis von gastrointestinalen pathogenen |
| AU2024234681A1 (en) | 2023-03-16 | 2025-09-04 | Gen-Probe Incorporated | Compositions and methods for detecting gastrointestinal parasites |
| KR20240153658A (ko) | 2023-04-17 | 2024-10-24 | 김보라 | 슬라이딩 강대상 |
Family Cites Families (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6515469A (de) * | 1965-01-22 | 1966-07-25 | ||
| US3817837A (en) * | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US4190496A (en) * | 1971-05-14 | 1980-02-26 | Syva Company | Homogeneous enzyme assay for antibodies |
| US4199559A (en) * | 1974-08-12 | 1980-04-22 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4383031A (en) * | 1975-04-28 | 1983-05-10 | Miles Laboratories, Inc. | Homogeneous chemiluminescent specific binding assay |
| US4174384A (en) * | 1975-06-30 | 1979-11-13 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| FR2422956A1 (fr) * | 1978-04-13 | 1979-11-09 | Pasteur Institut | Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede |
| US4318707A (en) * | 1978-11-24 | 1982-03-09 | Syva Company | Macromolecular fluorescent quencher particle in specific receptor assays |
| CA1185177A (en) * | 1981-07-17 | 1985-04-09 | Larry E. Morrison | Non-radiative energy transfer immunochemical technique |
| CA1190838A (en) * | 1981-07-17 | 1985-07-23 | Cavit Akin | Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer |
| DE3279029D1 (en) * | 1981-12-11 | 1988-10-20 | Welsh Nat School Med | Luminescent labelling materials and procedures |
| US4668640A (en) * | 1981-12-11 | 1987-05-26 | Abbott Laboratories | Fluorescence polarization immunoassay utilizing substituted carboxyfluoresceins |
| US4462931A (en) * | 1982-06-16 | 1984-07-31 | American Cyanamid Company | Enhanced aqueous chemiluminescent systems |
| US4508642A (en) * | 1983-04-21 | 1985-04-02 | World Victor B | Method of obtaining greater lifetime duration from chemiluminescent systems |
| US4640898A (en) * | 1983-08-01 | 1987-02-03 | University Of Health Sciences/The Chicago Medical School | Homogeneous fluorescence ligang binding assay based upon preferential alteration of the respective intensities of bound and free label by solvent components |
| US4816419A (en) * | 1983-08-01 | 1989-03-28 | University Of Health Sciences/The Chicago Medical School | Fluorescence ligand binding assay using charge-matched dye and solvent components |
| US4582789A (en) * | 1984-03-21 | 1986-04-15 | Cetus Corporation | Process for labeling nucleic acids using psoralen derivatives |
| AU580042B2 (en) * | 1984-03-22 | 1988-12-22 | Bresatec Limited | Non-radioactive biological probes |
| CA1260372A (en) * | 1984-04-27 | 1989-09-26 | Elazar Rabbani | Hybridization method for the detection of genetic materials |
| US4670379A (en) * | 1984-12-19 | 1987-06-02 | E. I. Du Pont De Nemours And Company | Polynucleotide hydridization assays employing catalyzed luminescence |
| ATE40572T1 (de) * | 1985-01-10 | 1989-02-15 | Molecular Diagnostics Inc | Photochemisches verfahren zum markieren von nucleinsaeuren zum nachweis in hybridisationsproben. |
| US4655969A (en) * | 1985-04-03 | 1987-04-07 | Richter Herbert P | Chemiluminescent systems |
| JP2509574B2 (ja) * | 1985-08-15 | 1996-06-19 | アモコ・コーポレーション | 標識付けした核酸 |
| JPS6261969A (ja) * | 1985-09-06 | 1987-03-18 | アモコ・コーポレーション | アクリジニウムエステルの合成法 |
| DE3545398A1 (de) * | 1985-12-20 | 1987-06-25 | Boehringer Mannheim Gmbh | Verfahren zur steigerung der quanten-ausbeute bei der oxidation von luminol durch peroxide in gegenwart von peroxidase |
| US4698183A (en) * | 1986-02-04 | 1987-10-06 | American Cyanamid Company | High light output-short duration chemiluminescent compositions |
| DE3645292C2 (de) * | 1986-08-22 | 1997-12-11 | Hoechst Ag | Chemilumineszenzimmunoassays und ein Verfahren zu ihrer Herstellung |
| US5110932A (en) * | 1986-10-06 | 1992-05-05 | Ciba Corning Diagnostics Corp. | Polysubstituted aryl acridinium esters |
| US4745181A (en) * | 1986-10-06 | 1988-05-17 | Ciba Corning Diagnostics Corp. | Polysubstituted aryl acridinium esters |
| US4918192A (en) * | 1986-10-06 | 1990-04-17 | Ciba Corning Diagnostics Corp. | Polysubstituted aryl acridinium esters |
| EP0273115B1 (de) * | 1986-10-22 | 1994-09-07 | Abbott Laboratories | Chemilumineszierende Acridinium- und Phenantridiniumsalze |
| JPS63107898A (ja) * | 1986-10-23 | 1988-05-12 | Natl Inst For Res In Inorg Mater | プラズマを用いるダイヤモンドの合成法 |
| US4927769A (en) * | 1987-07-08 | 1990-05-22 | Ciba Corning Diagnostics Corp. | Method for enhancement of chemiluminescence |
| KR970005898B1 (ko) * | 1987-09-21 | 1997-04-21 | 젠- 프로우브 인코퍼레이티드 | 뉴클레오티드 프로브에 대한 비-뉴클레오티드 연결시약 |
| US5283174A (en) * | 1987-09-21 | 1994-02-01 | Gen-Probe, Incorporated | Homogenous protection assay |
| PT88562B (pt) * | 1987-09-21 | 1994-02-28 | Ml Technology Ventures | Metodo de ensaio de proteccao homogeneo para a deteccao de um analito |
| US5185439A (en) * | 1987-10-05 | 1993-02-09 | Gen-Probe Incorporated | Acridinium ester labelling and purification of nucleotide probes |
| US4883898A (en) * | 1987-12-10 | 1989-11-28 | University Of Chicago | Chemiluminescent compounds |
| NL8703075A (nl) * | 1987-12-18 | 1989-07-17 | Nederlanden Staat | Acridiniumverbindingen als chemiluminescentie-merkstof. |
| US5321136A (en) * | 1987-12-31 | 1994-06-14 | London Diagnostics, Inc. | Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom |
| US5290936A (en) * | 1987-12-31 | 1994-03-01 | London Diagnostics, Inc. | Nitro substituted chemiluminescent labels and their conjugates, and assays therefrom |
| NZ227506A (en) * | 1987-12-31 | 1992-06-25 | London Diagnostics Inc | Specific binding assays using chemiluminescent compounds |
| US5338847A (en) * | 1987-12-31 | 1994-08-16 | London Diagnostics, Inc. | Hydrolytically stable chemiluminescent labels and their conjugates, and assays therefrom by adduct formation |
| DE3844954C2 (de) * | 1988-02-20 | 1998-07-16 | Hoechst Ag | Spezielle chemilumineszierende Acridinderivate und ihre Verwendung in Lumineszenzimmunoassays |
| US4950613A (en) * | 1988-02-26 | 1990-08-21 | Gen-Probe Incorporated | Proteted chemiluminescent labels |
| AU634716B2 (en) * | 1988-08-01 | 1993-03-04 | Ciba Corning Diagnostics Corp. | Method for detection of an analyte using acridinium esters and liposomes |
| US5241070A (en) * | 1988-09-26 | 1993-08-31 | Ciba Corning Diagnostics Corp. | Nucleophilic polysubstituted aryl acridinium esters and uses thereof |
| CA1339491C (en) * | 1988-09-26 | 1997-10-07 | Say-Jong Law | Nucleophilic polysubstituted aryl acridinium ester and uses thereof |
| US5093270A (en) * | 1989-05-24 | 1992-03-03 | Ciba Corning Diagnostics Corp. | Method for enhancing signal release from liposomes using water-miscible alcohols |
| GB2233451B (en) * | 1989-06-27 | 1993-09-15 | Tropix Inc | Chemiluminescence enhancement |
| JPH0335147A (ja) * | 1989-07-03 | 1991-02-15 | Doujin Kagaku Kenkyusho:Kk | 化学発光の検出 |
| CA2094803A1 (en) * | 1990-10-26 | 1992-04-27 | Robert E. Klem | Process for the synthesis of oligomers |
| WO1992009580A1 (en) * | 1990-11-21 | 1992-06-11 | Beckman Instruments, Inc. | Chemiluminescent compounds |
| DE69132765T2 (de) * | 1990-12-24 | 2002-02-21 | Enzo Diagnostics, Inc. | Verfahren zum Nachweis eines Zielpolynukleotids in einer Probe unter Verwendung eines Reagenz, das den Hintergrund verringert, und eine dieses Reagenz enthaltende Zusammensetzung und Kit. |
| JPH0579985A (ja) * | 1991-09-24 | 1993-03-30 | Kyoto Daiichi Kagaku:Kk | 化学発光増強剤及び増強方法 |
| JPH05255264A (ja) * | 1992-03-13 | 1993-10-05 | Sanyo Chem Ind Ltd | 標識剤および標識されたリガンドの製法 |
| KR950701392A (ko) * | 1992-05-06 | 1995-03-23 | 다니엘 엘. 카시안 | 인체 B형 간염 바이러스에 대한 핵산 증폭 올리고뉴클레오티드 및 프로브(Nucleic Acide Amplification Oligonucleotides and Probes to Human Hepatitis B Birus) |
| JP3248628B2 (ja) * | 1992-06-25 | 2002-01-21 | 国際試薬株式会社 | 化学発光性化合物およびこれを用いるアッセイ法 |
| EP0651752A1 (de) * | 1992-07-20 | 1995-05-10 | Behringwerke Ag | Chemilumineszierende derivate und methoden deren anwendung |
| JP3207933B2 (ja) * | 1992-09-09 | 2001-09-10 | 株式会社ヤトロン | アクリジニウム誘導体の発光方法及びそれを用いた検査対象物質の検出方法 |
| EP0602524A1 (de) * | 1992-12-15 | 1994-06-22 | Hoechst Aktiengesellschaft | Chemilumineszenzmarkierte Gensonden und ihre Verwendung in Gensondentesten |
| JP3584379B2 (ja) * | 1993-02-04 | 2004-11-04 | 持田製薬株式会社 | アクリジニウム化合物およびアクリジニウム化合物複合体 |
| AU686616B2 (en) * | 1993-03-26 | 1998-02-12 | Gen-Probe Incorporated | Detection of human immunodeficiency virus type 1 |
| US5491072A (en) * | 1993-05-17 | 1996-02-13 | Lumigen, Inc. | N-alkylacridan carboxyl derivatives useful for chemiluminescent detection |
| AU692816B2 (en) * | 1993-07-19 | 1998-06-18 | Gen-Probe Incorporated | Oligonucleotide screening assay |
| JPH07330838A (ja) * | 1994-06-10 | 1995-12-19 | Nippon Oil & Fats Co Ltd | アクリダン基含有高分子および化学発光方法 |
| JP3694044B2 (ja) * | 1994-06-22 | 2005-09-14 | 株式会社三菱化学ヤトロン | アクリジニウム誘導体の発光方法及びその方法を用いた検査対象物質の検出方法 |
| ATE340866T1 (de) * | 1994-10-28 | 2006-10-15 | Gen Probe Inc | Zusammensetzungen und verfahren für die gleichzeitige detektion und quantifizierung von einer mehrheit spezifischer nuklein säure sequenzen |
-
1995
- 1995-06-07 US US08/478,221 patent/US5731148A/en not_active Expired - Lifetime
-
1996
- 1996-05-23 CA CA002222556A patent/CA2222556C/en not_active Expired - Fee Related
- 1996-05-23 AU AU60244/96A patent/AU703605B2/en not_active Ceased
- 1996-05-23 JP JP50074597A patent/JP3577085B2/ja not_active Expired - Lifetime
- 1996-05-23 WO PCT/US1996/007776 patent/WO1996041197A1/en not_active Ceased
- 1996-05-23 KR KR1019970708941A patent/KR19990022460A/ko not_active Withdrawn
- 1996-06-03 AT AT96108880T patent/ATE246807T1/de not_active IP Right Cessation
- 1996-06-03 DK DK96108880T patent/DK0747706T3/da active
- 1996-06-03 ES ES96108880T patent/ES2203656T3/es not_active Expired - Lifetime
- 1996-06-03 EP EP96108880A patent/EP0747706B1/de not_active Expired - Lifetime
- 1996-06-03 DE DE69629333T patent/DE69629333T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU703605B2 (en) | 1999-03-25 |
| CA2222556C (en) | 2002-06-11 |
| DE69629333T2 (de) | 2004-06-24 |
| KR19990022460A (ko) | 1999-03-25 |
| EP0747706A1 (de) | 1996-12-11 |
| ES2203656T3 (es) | 2004-04-16 |
| JP3577085B2 (ja) | 2004-10-13 |
| DK0747706T3 (da) | 2003-11-24 |
| DE69629333D1 (de) | 2003-09-11 |
| US5731148A (en) | 1998-03-24 |
| WO1996041197A1 (en) | 1996-12-19 |
| EP0747706B1 (de) | 2003-08-06 |
| CA2222556A1 (en) | 1996-12-19 |
| JP2002515118A (ja) | 2002-05-21 |
| AU6024496A (en) | 1996-12-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE246807T1 (de) | Adduktabschirmungstest | |
| DK0941468T3 (da) | Et-trins-hybridimmunochromatografisk udstyr og fremgangsmåde til anvendelse heraf | |
| BR9710836A (pt) | Ensaio de analitos usando marcas em partìculas | |
| EP0805215A3 (de) | Diagnostische Methoden und Proben | |
| ATE515693T1 (de) | Nachweis einer zielsubstanz in einer probe | |
| ATE128237T1 (de) | Test für hepatitis-c. | |
| ATE371189T1 (de) | Liganden-bindetest und kit mit einer abtrennzone für störende probenkomponenten | |
| AU637489B2 (en) | Conjugate recovery binding assays and devices | |
| ES2079434T3 (es) | Ensayos de ligandos-receptores que utilizan un umbral. | |
| AU2001289853A1 (en) | Multianalyte determination system and methods | |
| EP1019724A4 (de) | Diagnostische tests und kits für clostridium difficile | |
| BR9811406A (pt) | Dispositivo para detenção da presença de pelo menos um analito em uma amostra biológica, kit para detenção da presença de pelo menos um analito em uma amostra biológica, e, processo de detecção da presença de pelo menos um analito em uma amostra biológica | |
| ATE343134T1 (de) | Detektionsvorrichtung und -verfahren | |
| FI964003A0 (fi) | Kemiallisten analyysien kalibrointimenetelmä | |
| ES2184260T3 (es) | Sistema de ensayo que utiliza particulas magneticas. | |
| ES2145746T3 (es) | Analisis de deteccion de hepatitis c. | |
| KR970022313A (ko) | 요중 단백질의 검출 방법 | |
| ES2112898T3 (es) | Metodo de ensayo. | |
| CA2303123A1 (en) | Method for detecting antibodies in a sample | |
| ES2094124T3 (es) | Ensayo-inmunologico de anticuerpos contra hiv. | |
| NO911001L (no) | Lysstabile fysikalske fremkallere. | |
| AU4624200A (en) | Identification of ligands for orphan receptors using mass spectrometry | |
| ES2169211T3 (es) | Ensayos de proteccion de micelas. | |
| ATE278193T1 (de) | Verfahren zum testen eines asialoglycoproteinrezeptors und testreagenz dafür | |
| ATE128552T1 (de) | Kalibrierungsmethode von systemen für enzymimmuntests. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0747706 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |